HK1155450A1 - Tertiary amine derivatives as phosphodiesterase-4 inhibitors -4 - Google Patents
Tertiary amine derivatives as phosphodiesterase-4 inhibitors -4Info
- Publication number
- HK1155450A1 HK1155450A1 HK11109767.9A HK11109767A HK1155450A1 HK 1155450 A1 HK1155450 A1 HK 1155450A1 HK 11109767 A HK11109767 A HK 11109767A HK 1155450 A1 HK1155450 A1 HK 1155450A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- phosphodiesterase
- inhibitors
- tertiary amine
- amine derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08007284A EP2110375A1 (en) | 2008-04-14 | 2008-04-14 | Phosphodiesterase-4 inhibitors belonging to the tertiary amine class |
PCT/EP2009/002242 WO2009127320A1 (en) | 2008-04-14 | 2009-03-27 | Tertiary amine derivatives as phosphodiesterase-4 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1155450A1 true HK1155450A1 (en) | 2012-05-18 |
Family
ID=39731427
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11109767.9A HK1155450A1 (en) | 2008-04-14 | 2011-09-16 | Tertiary amine derivatives as phosphodiesterase-4 inhibitors -4 |
Country Status (13)
Country | Link |
---|---|
US (1) | US7820698B2 (es) |
EP (2) | EP2110375A1 (es) |
JP (1) | JP5492190B2 (es) |
KR (1) | KR101208193B1 (es) |
CN (1) | CN102007117B (es) |
AU (1) | AU2009238014B2 (es) |
BR (1) | BRPI0907267A2 (es) |
CA (1) | CA2721240A1 (es) |
EA (1) | EA018069B1 (es) |
HK (1) | HK1155450A1 (es) |
MX (1) | MX2010011016A (es) |
WO (1) | WO2009127320A1 (es) |
ZA (1) | ZA201007317B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2022783A1 (en) | 2007-08-08 | 2009-02-11 | CHIESI FARMACEUTICI S.p.A. | "Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors" |
EP2216327A1 (en) | 2009-02-06 | 2010-08-11 | CHIESI FARMACEUTICI S.p.A. | Benzoic acid (1-phenyl-2-pyridin-4-yl)ethyl esters as phosphodiesterase inhibitors |
CA2807406C (en) | 2010-08-03 | 2018-12-11 | Chiesi Farmaceutici S.P.A. | Pharmaceutical formulation comprising a phosphodiesterase inhibitor |
CA2838435A1 (en) | 2011-06-06 | 2012-12-13 | Chiesi Farmaceutici S.P.A. | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors |
CN103827088B (zh) | 2011-09-26 | 2017-10-13 | 奇斯药制品公司 | 作为磷酸二酯酶抑制剂的1‑苯基‑2‑吡啶基烷基醇的衍生物 |
KR20150022789A (ko) | 2012-06-04 | 2015-03-04 | 키에시 파르마슈티시 엣스. 피. 에이. | 포스포디에스테라제 억제제로서 1-페닐-2-피리디닐 알킬 알코올의 유도체 |
WO2014086855A1 (en) | 2012-12-05 | 2014-06-12 | Chiesi Farmaceutici S.P.A. | Phenylethylpyridine derivatives as pde4-inhibitors |
RU2015121043A (ru) | 2012-12-05 | 2017-01-11 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Производные фенилэтилпиридина в качестве ингибиторов PDE-4 |
KR20150090253A (ko) | 2012-12-05 | 2015-08-05 | 키에시 파르마슈티시 엣스. 피. 에이. | Pde4-억제제로서 페닐에틸피리딘 유도체 |
KR102192739B1 (ko) | 2012-12-05 | 2020-12-18 | 키에시 파르마슈티시 엣스. 피. 에이. | 포스포디에스테라제 억제제로서 1-페닐-2-피리디닐 알킬 알코올의 유도체 |
US9427376B2 (en) | 2013-10-10 | 2016-08-30 | Chiesi Farmaceutici S.P.A. | Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient |
WO2017089347A1 (en) | 2015-11-25 | 2017-06-01 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and pharmaceutical compositions for the treatment of braf inhibitor resistant melanomas |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
YU57603A (sh) * | 2001-01-22 | 2006-08-17 | Memory Pharmaceuticals Corporation | Inhibitori fosfodiesteraze 4 |
CA2492907A1 (en) * | 2002-07-19 | 2004-01-29 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors, including n-substituted aniline and diphenylamine analogs |
EP1569908B1 (en) * | 2002-11-19 | 2010-09-15 | Memory Pharmaceuticals Corporation | Pyridine n-oxide compounds as phosphodiesterase 4 inhibitors |
EP1443330A1 (en) * | 2003-02-03 | 2004-08-04 | Gilson Sas | Methods, rack and device for preparing samples for analysis |
MY141255A (en) * | 2003-12-11 | 2010-03-31 | Memory Pharm Corp | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs |
US20070049611A1 (en) * | 2005-06-10 | 2007-03-01 | Talamas Francisco X | Phosphodiesterase 4 inhibitors |
CN101490004B (zh) * | 2006-07-14 | 2012-01-11 | 奇斯药制品公司 | 作为磷酸二酯酶抑制剂的1-苯基-2-吡啶基烯基醇的衍生物 |
JP5254231B2 (ja) * | 2006-08-09 | 2013-08-07 | バジリア ファルマスーチカ アーゲー | 炎症性及びアレルギー性疾患に対して有用な新規マクロライド |
-
2008
- 2008-04-14 EP EP08007284A patent/EP2110375A1/en not_active Withdrawn
-
2009
- 2009-03-27 EA EA201001481A patent/EA018069B1/ru not_active IP Right Cessation
- 2009-03-27 BR BRPI0907267-5A patent/BRPI0907267A2/pt not_active IP Right Cessation
- 2009-03-27 CN CN200980113261.1A patent/CN102007117B/zh not_active Expired - Fee Related
- 2009-03-27 AU AU2009238014A patent/AU2009238014B2/en not_active Ceased
- 2009-03-27 WO PCT/EP2009/002242 patent/WO2009127320A1/en active Application Filing
- 2009-03-27 CA CA2721240A patent/CA2721240A1/en not_active Abandoned
- 2009-03-27 MX MX2010011016A patent/MX2010011016A/es active IP Right Grant
- 2009-03-27 JP JP2011504342A patent/JP5492190B2/ja not_active Expired - Fee Related
- 2009-03-27 EP EP09731537A patent/EP2268632B1/en active Active
- 2009-03-27 KR KR1020107023045A patent/KR101208193B1/ko not_active IP Right Cessation
- 2009-04-14 US US12/423,227 patent/US7820698B2/en not_active Expired - Fee Related
-
2010
- 2010-10-13 ZA ZA2010/07317A patent/ZA201007317B/en unknown
-
2011
- 2011-09-16 HK HK11109767.9A patent/HK1155450A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EA201001481A1 (ru) | 2011-06-30 |
AU2009238014A1 (en) | 2009-10-22 |
CN102007117B (zh) | 2014-06-25 |
JP5492190B2 (ja) | 2014-05-14 |
CN102007117A (zh) | 2011-04-06 |
EA018069B1 (ru) | 2013-05-30 |
BRPI0907267A2 (pt) | 2015-07-21 |
MX2010011016A (es) | 2010-11-09 |
WO2009127320A1 (en) | 2009-10-22 |
KR101208193B1 (ko) | 2012-12-04 |
KR20100128330A (ko) | 2010-12-07 |
EP2268632A1 (en) | 2011-01-05 |
JP2011517687A (ja) | 2011-06-16 |
EP2268632B1 (en) | 2012-08-08 |
US7820698B2 (en) | 2010-10-26 |
AU2009238014B2 (en) | 2013-07-18 |
US20090258905A1 (en) | 2009-10-15 |
CA2721240A1 (en) | 2009-10-22 |
EP2110375A1 (en) | 2009-10-21 |
ZA201007317B (en) | 2012-01-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1256310A1 (zh) | N-磺酰基吡咯衍生物 | |
HK1155450A1 (en) | Tertiary amine derivatives as phosphodiesterase-4 inhibitors -4 | |
IL210548A (en) | History of spiroamino dihydraziazine | |
EP2376493A4 (en) | DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVE | |
EP2376494A4 (en) | DIHYDROPYRIMIDOPIRYMIDINE DERIVATIVES | |
EP2380877A4 (en) | PYRIDINE-3-CARBONSÄUREAMIDDERIVAT | |
EP2331543A4 (en) | 3-DÉSAZANEPLANOCINE DERIVATIVES | |
IL210406A0 (en) | Pyrrolopyridinylpyrimidin - 2 - ylamine derivatives | |
HK1158189A1 (en) | Morpholinopurine derivative | |
EP2291078A4 (en) | OXAZOLBENZIMIDAZOLDERIVATE | |
EP2269993A4 (en) | 2-aminoquinazoline DERIVATIVE | |
EP2279532A4 (en) | OXAZOLBENZIMIDAZOLDERIVATE | |
ZA201005769B (en) | Bicycloamine derivative | |
IL208623A0 (en) | Cyclopentylacrylamide derivative | |
IL210613A0 (en) | Novel acylaminobenzamide derivatives | |
IL208336A0 (en) | Pyrisazinone derivatives | |
IL210164A0 (en) | Thiazolylpiperidine derivatives | |
IL208548A0 (en) | 2-phenyl-4-cyclopropyl-pyrimidine derivatives | |
ZA201006992B (en) | Hydroxyquinoxalinecarboxamide derivative | |
EP2292613A4 (en) | DIHYDROINDOLINONDERIVATE | |
GB0921210D0 (en) | Novel heterocyclic derivatives | |
EP2248811A4 (en) | 2-OXOCHROMENE DERIVATIVE | |
IL212683A0 (en) | Biphenylacetamide derivative | |
EP2332925A4 (en) | NOVEL DIHYDROTRIAZINE DERIVATIVE | |
GB0921967D0 (en) | Novel Aryloxyanilide Derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20190327 |