HK1153268A1 - Methods and compositions for diagnosis and prognosis of renal injury and renal failure - Google Patents

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Info

Publication number
HK1153268A1
HK1153268A1 HK11107251.6A HK11107251A HK1153268A1 HK 1153268 A1 HK1153268 A1 HK 1153268A1 HK 11107251 A HK11107251 A HK 11107251A HK 1153268 A1 HK1153268 A1 HK 1153268A1
Authority
HK
Hong Kong
Prior art keywords
renal
prognosis
diagnosis
compositions
methods
Prior art date
Application number
HK11107251.6A
Other languages
English (en)
Chinese (zh)
Inventor
Joseph Anderberg
Jeff Gray
Paul Mcpherson
Kevin Nakamura
Original Assignee
Astute Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astute Medical Inc filed Critical Astute Medical Inc
Publication of HK1153268A1 publication Critical patent/HK1153268A1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK11107251.6A 2008-08-28 2011-07-12 Methods and compositions for diagnosis and prognosis of renal injury and renal failure HK1153268A1 (en)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US9273308P 2008-08-28 2008-08-28
US9324408P 2008-08-29 2008-08-29
US9327208P 2008-08-29 2008-08-29
US9292608P 2008-08-29 2008-08-29
US9315408P 2008-08-29 2008-08-29
US9326408P 2008-08-29 2008-08-29
US9324708P 2008-08-29 2008-08-29
US9326208P 2008-08-29 2008-08-29
US9290508P 2008-08-29 2008-08-29
US9326608P 2008-08-29 2008-08-29
US9326308P 2008-08-29 2008-08-29
US9324908P 2008-08-29 2008-08-29
US9291208P 2008-08-29 2008-08-29
PCT/US2009/055449 WO2010025424A1 (en) 2008-08-28 2009-08-28 Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Publications (1)

Publication Number Publication Date
HK1153268A1 true HK1153268A1 (en) 2012-03-23

Family

ID=41721965

Family Applications (3)

Application Number Title Priority Date Filing Date
HK11107251.6A HK1153268A1 (en) 2008-08-28 2011-07-12 Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK14111890A HK1198391A1 (en) 2008-08-28 2014-11-25 Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK16101184.6A HK1213320A1 (zh) 2008-08-28 2016-02-02 用於診斷和預後腎損傷和腎衰竭的方法和組合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
HK14111890A HK1198391A1 (en) 2008-08-28 2014-11-25 Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK16101184.6A HK1213320A1 (zh) 2008-08-28 2016-02-02 用於診斷和預後腎損傷和腎衰竭的方法和組合物

Country Status (12)

Country Link
US (2) US11150250B2 (de)
EP (3) EP2324355B1 (de)
JP (2) JP2012501456A (de)
KR (1) KR20110073471A (de)
CN (2) CN105067819B (de)
AU (1) AU2009285550B2 (de)
BR (1) BRPI0917711A2 (de)
CA (1) CA2735587A1 (de)
HK (3) HK1153268A1 (de)
MX (2) MX2011002233A (de)
NZ (2) NZ591437A (de)
WO (1) WO2010025424A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ591437A (en) 2008-08-28 2013-07-26 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP5947544B2 (ja) * 2008-08-29 2016-07-06 アスチュート メディカル，インコーポレイテッド 腎損傷および腎不全の診断および予後のための方法および組成物
CA2740923A1 (en) * 2008-10-21 2010-04-29 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
ES2836218T3 (es) 2008-10-21 2021-06-24 Astute Medical Inc Procedimientos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal
EP2913676A1 (de) 2008-11-10 2015-09-02 Astute Medical, Inc. Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz
WO2010059996A1 (en) * 2008-11-22 2010-05-27 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US9229010B2 (en) 2009-02-06 2016-01-05 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EA201290056A1 (ru) 2009-08-07 2012-08-30 Астьют Медикал, Инк. Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
CN104793000A (zh) 2009-11-07 2015-07-22 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断及预后的方法和组合物
CA2784889C (en) 2009-12-20 2018-06-19 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US20120156701A1 (en) * 2009-12-20 2012-06-21 Joseph Anderberg Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2011097539A1 (en) 2010-02-05 2011-08-11 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP5998057B2 (ja) 2010-02-26 2016-11-30 アスチュート メディカル，インコーポレイテッド 腎損傷および腎不全の診断と予後のための方法と組成物
WO2011109446A1 (en) * 2010-03-01 2011-09-09 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure in a non-surgical icu population
NZ703055A (en) 2010-06-23 2016-07-29 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2585827A4 (de) 2010-06-23 2013-12-04 Astute Medical Inc Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
US10557856B2 (en) * 2010-09-24 2020-02-11 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biomarkers of renal injury
EP2619231B1 (de) * 2010-09-24 2016-12-21 Astute Medical, Inc. Verfahren zur bewertung von nierenläsionen mithilfe von hyaluronsäure
WO2012094658A2 (en) * 2011-01-08 2012-07-12 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2729803A4 (de) * 2011-07-09 2015-08-05 Astute Medical Inc Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
AU2012312907A1 (en) * 2011-08-26 2014-03-13 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2783213B1 (de) * 2011-11-22 2017-09-13 Astute Medical, Inc. Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
EP2788759B1 (de) 2011-12-08 2019-02-20 Astute Medical, Inc. Verfahren und verwendungen zur diagnose von nierenverletzungen und niereninsuffizienz
EP4105657A1 (de) 2013-01-17 2022-12-21 Astute Medical, Inc. Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz
WO2014134223A1 (en) * 2013-02-26 2014-09-04 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN110007084B (zh) 2013-12-03 2022-11-18 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断和预后的方法和组合物
US9957219B2 (en) 2013-12-04 2018-05-01 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds
WO2015119899A1 (en) 2014-02-06 2015-08-13 Merck Sharp & Dohme Corp. Antidiabetic compounds
GB201404789D0 (en) * 2014-03-18 2014-04-30 Univ Dundee Biomarkers
WO2016164854A1 (en) 2015-04-09 2016-10-13 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP2019523889A (ja) 2016-06-06 2019-08-29 アスチュート メディカル，インコーポレイテッド インスリン様増殖因子結合タンパク質７およびメタロプロテアーゼ２の組織阻害剤を使用する急性腎臓傷害の管理
WO2017216325A1 (en) * 2016-06-17 2017-12-21 F. Hoffmann-La Roche Ag In vitro nephrotoxicity screening assay
CN110431422A (zh) 2017-02-06 2019-11-08 机敏医药股份有限公司 用于肾损伤和肾衰竭的诊断和预后的方法和组合物
EP3695224A4 (de) * 2017-10-12 2021-12-29 Cedars-Sinai Medical Center Prognose- und progressionsbiomarker für chronische nierenkrankheit
WO2020092909A1 (en) * 2018-11-02 2020-05-07 Prevencio, Inc. Prognostic and diagnostic methods for risk of acute kidney injury
CN110221337B (zh) * 2019-06-28 2022-07-01 南华大学 一种利用α-1抗蛋白酶评价铀矿粉尘内照射生物损伤的方法

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1429031A1 (ru) 1986-06-20 1988-10-07 Калининский Государственный Медицинский Институт Способ дифференциальной диагностики гломерулонефрита и пиелонефрита
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5028535A (en) 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5939272A (en) 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
WO1992005282A1 (en) 1990-09-14 1992-04-02 Biosite Diagnostics, Inc. Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
US5955377A (en) 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
JPH06506688A (ja) 1991-04-10 1994-07-28 バイオサイト・ダイアグノスティックス・インコーポレイテッド クロストークインヒビターおよびその使用
ES2150915T3 (es) 1991-04-12 2000-12-16 Biosite Diagnostics Inc Nuevos conjugados y dosificados destinados para la deteccion simultanea de ligandos multiples.
US5885527A (en) 1992-05-21 1999-03-23 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membrances
US6143576A (en) 1992-05-21 2000-11-07 Biosite Diagnostics, Inc. Non-porous diagnostic devices for the controlled movement of reagents
US5494829A (en) 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5824799A (en) 1993-09-24 1998-10-20 Biosite Diagnostics Incorporated Hybrid phthalocyanine derivatives and their uses
US6498142B1 (en) * 1996-05-06 2002-12-24 Curis, Inc. Morphogen treatment for chronic renal failure
JP4602482B2 (ja) * 1996-05-24 2010-12-22 バイオジェン・アイデック・エムエイ・インコーポレイテッド 組織再生のモジュレーター
US5753455A (en) 1996-09-03 1998-05-19 Bayer Corporation Method for the detection of lysozyme using a protein error indicator dye in conjunction with an alkane sulfonic acid
CA2270423C (en) * 1996-10-31 2009-09-15 Mochida Pharmaceutical Co., Ltd. Prophylactic/therapeutic agent
US6113855A (en) 1996-11-15 2000-09-05 Biosite Diagnostics, Inc. Devices comprising multiple capillarity inducing surfaces
US5947124A (en) 1997-03-11 1999-09-07 Biosite Diagnostics Incorporated Diagnostic for determining the time of a heart attack
US5773430A (en) 1997-03-13 1998-06-30 Research Foundation Of State University Of New York Serine proteinase inhibitory activity by hydrophobic tetracycline
US6057098A (en) 1997-04-04 2000-05-02 Biosite Diagnostics, Inc. Polyvalent display libraries
WO1998055508A2 (en) 1997-06-03 1998-12-10 Sagami Chemical Research Center HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS
US20060223077A1 (en) * 1997-06-06 2006-10-05 Human Genome Sciences, Inc. 207 human secreted proteins
US6218122B1 (en) * 1998-06-19 2001-04-17 Rosetta Inpharmatics, Inc. Methods of monitoring disease states and therapies using gene expression profiles
US6958147B1 (en) * 1998-10-26 2005-10-25 Licentia Ltd Use of VEGF-C to prevent restenosis
CN1331801A (zh) * 1998-12-21 2002-01-16 莫纳什大学 肾病检测及治疗
RU2180965C1 (ru) 2000-07-03 2002-03-27 Габбасова Наталья Вадимовна Способ дифференциальной диагностики заболеваний почек
EP1405072A2 (de) * 2000-12-29 2004-04-07 Oxford GlycoSciences (UK) Limited Proteine, gene und ihre verwendungen zur diagnose und behandlung von nierenkrankheiten
US20060088823A1 (en) * 2001-03-29 2006-04-27 Brian Haab Microarray gene expression profiling in clear cell renal cell carcinoma : prognosis and drug target identification
US20070015146A1 (en) * 2001-05-22 2007-01-18 Gene Logic, Inc. Molecular nephrotoxicology modeling
US7235358B2 (en) * 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US20030003588A1 (en) * 2001-06-28 2003-01-02 Comper Wayne D. Method for kidney disease detection by protein profiling
HUP0400659A3 (en) * 2001-07-24 2005-06-28 Zhu Zhou Woodbridge Methods, compositions and kits relating to chitinases and chitinase-like molecules and inflammatory disease
US6784154B2 (en) * 2001-11-01 2004-08-31 University Of Utah Research Foundation Method of use of erythropoietin to treat ischemic acute renal failure
US8404229B2 (en) * 2001-12-07 2013-03-26 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to treat acute tubular necrosis
GB0130557D0 (en) 2001-12-20 2002-02-06 Serono Internat S A Proteins
CA2478288A1 (en) 2002-03-07 2003-09-12 Adrian Woolfson Scd fingerprints
AU2003214604A1 (en) * 2002-03-21 2003-10-08 Hadasit Medical Research Services And Development Ltd. Peripheral blood cell markers useful for diagnosing multiple sclerosis and methods and kits utilizing same
US7138230B2 (en) * 2002-12-06 2006-11-21 Renovar, Inc. Systems and methods for characterizing kidney diseases
US7138229B2 (en) * 2002-12-06 2006-11-21 Renovar, Inc. Systems and methods for characterizing kidney diseases
EP1513543B1 (de) * 2002-05-23 2010-10-06 The Trustees of The University of Pennsylvania Fas peptid-mimetika und ihre verwendungszwecke
AU2003281287A1 (en) 2002-07-04 2004-01-23 Oxford Glycosciences (Uk) Ltd Toxicity markers
US6941172B2 (en) * 2002-11-18 2005-09-06 Zvi Nachum Method and device for restoring kidney function using electromagnetic stimulation
US20060063156A1 (en) * 2002-12-06 2006-03-23 Willman Cheryl L Outcome prediction and risk classification in childhood leukemia
CN1791797A (zh) 2003-03-27 2006-06-21 儿童医院医疗中心 用于检测肾小管细胞损伤的早发的方法和试剂盒
AU2004229501B2 (en) * 2003-04-11 2011-08-18 Medimmune, Llc Recombinant IL-9 antibodies and uses thereof
WO2005002416A2 (en) * 2003-06-04 2005-01-13 Joslin Diabetes Center, Inc. Predictors of renal disease
US20050148029A1 (en) * 2003-09-29 2005-07-07 Biosite, Inc. Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes
US20080227733A1 (en) 2003-10-30 2008-09-18 Immune Disease Institute, Inc. Method for Treating and Preventing Ischemia-Reperfusion Injury Using Rna Interfering Agent
GB0329288D0 (en) * 2003-12-18 2004-01-21 Inverness Medical Switzerland Monitoring method and apparatus
EP1727564A1 (de) 2004-03-17 2006-12-06 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Cd44 als ziel zur verminderung/vermeidung des ischämie-reperfusionsschadens
JP2007535324A (ja) * 2004-04-26 2007-12-06 チルドレンズ メディカル センター コーポレーション 疾患検出のための血小板バイオマーカー
US20050272101A1 (en) * 2004-06-07 2005-12-08 Prasad Devarajan Method for the early detection of renal injury
US7588892B2 (en) * 2004-07-19 2009-09-15 Entelos, Inc. Reagent sets and gene signatures for renal tubule injury
US20080038192A1 (en) * 2004-07-19 2008-02-14 Neurochem Inc. Diagnostic Methods Of Multiple Organ Amyloidosis
US7141382B1 (en) * 2004-10-12 2006-11-28 Parikh Chirag R Methods for detection of IL-18 as an early marker for diagnosis of acute renal failure and predictor of mortality
SI1831699T1 (sl) 2004-12-20 2010-03-31 Antibodyshop As Določanje nevtrofilnega lipokalina asociiranega z želatinazo ngal kot diagnostičnega markerja za ledvične bolezni
WO2006083986A2 (en) 2005-02-01 2006-08-10 Government Of The U.S.A, As Represented By The Secretary Department Of Health & Human Services Biomarkers for tissue status
EP1869213A4 (de) * 2005-03-14 2008-05-14 Univ Leland Stanford Junior Verfahren und zusammensetzungen zur bewertung der haltbarkeit eines pfropfs im körper eines empfängers fester organtransplantate
US7608413B1 (en) * 2005-03-25 2009-10-27 Celera Corporation Kidney disease targets and uses thereof
US20070037232A1 (en) * 2005-03-31 2007-02-15 Barasch Jonathan M Detection of NGAL in chronic renal disease
NZ562928A (en) * 2005-04-18 2011-01-28 Mitomics Inc Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers
US20070087387A1 (en) * 2005-04-21 2007-04-19 Prasad Devarajan Method for the Early Detection of Renal Disease Using Proteomics
CA2614935A1 (en) * 2005-07-21 2007-02-01 The Johns Hopkins University Methods of detecting and treating acute kidney injury
US7759077B2 (en) * 2005-08-02 2010-07-20 Shariat Shahrokh F Soluble fas urinary marker for the detection of bladder transitional cell carcinoma
EP1757940A1 (de) * 2005-08-26 2007-02-28 Cézanne S.A.S. In vitro Methode zur Diagnose und zum Monitoring von Nierenzellkarzinom unter Verwendung von MMP-7 als humoraler Biomarker für Nierenzellkarzinom
JP2009510478A (ja) 2005-10-03 2009-03-12 バイオサイト インコーポレイテッド 全身性炎症反応症候群の診断および／または予後診断のための方法および組成物
US20080090304A1 (en) * 2006-10-13 2008-04-17 Barasch Jonathan Matthew Diagnosis and monitoring of chronic renal disease using ngal
US8329408B2 (en) * 2005-10-31 2012-12-11 Bayer Healthcare Llc Methods for prognosis and monitoring cancer therapy
US10716749B2 (en) * 2005-11-03 2020-07-21 Palo Alto Investors Methods and compositions for treating a renal disease condition in a subject
US20080133141A1 (en) * 2005-12-22 2008-06-05 Frost Stephen J Weighted Scoring Methods and Use Thereof in Screening
TW200726845A (en) * 2006-01-02 2007-07-16 Nat Defense Medical Ct Biomarker molecular of renal illness and detecting method for the same
GB0605217D0 (en) * 2006-03-15 2006-04-26 Novartis Ag Method and compositions for assessing acute rejection
GB0606776D0 (en) * 2006-04-03 2006-05-10 Novartis Pharma Ag Predictive biomarkers for chronic allograft nephropathy
US7662578B2 (en) * 2006-04-21 2010-02-16 Children's Hospital Medical Center Method and kit for the early detection of impaired renal status
US20080038269A1 (en) * 2006-05-25 2008-02-14 Mount Sinai Hospital Methods for detecting and treating kidney disease
WO2008084331A2 (en) 2006-06-21 2008-07-17 Hopitaux Universitaires De Geneve Biomarkers for renal disorders
WO2008005375A2 (en) * 2006-06-30 2008-01-10 Merck & Co., Inc. Kidney toxicity biomarkers
WO2008009132A1 (en) * 2006-07-21 2008-01-24 The Governors Of The University Of Alberta Tissue rejection
GB0617429D0 (en) 2006-09-05 2006-10-18 Electrophoretics Ltd Markers of renal transplant rejection and renal damage
US20080206794A1 (en) * 2006-09-15 2008-08-28 Renovar Incorporated Systems And Methods For Characterizing Contrast Induced-Nephropathy
WO2008060607A2 (en) 2006-11-14 2008-05-22 Biosite Incorporated Methods and compositions for monitoring and risk prediction in cardiorenal syndrome
EP2064550B1 (de) * 2006-12-08 2015-02-25 The Children's Hospital Of Philadelphia Verwendung von prrg4 in tumordiagnoseverfahren
GB0701626D0 (en) * 2007-01-22 2007-03-07 Cambridge Entpr Ltd Methods and biomarkers for diagnosing and monitoring psychotic disorders
WO2008104803A2 (en) 2007-02-26 2008-09-04 Oxford Genome Sciences (Uk) Limited Proteins
US8221995B2 (en) * 2007-03-23 2012-07-17 Seok-Won Lee Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes
EP2479570A3 (de) 2007-03-26 2012-09-26 Novartis AG Prognostische Biomarker der renalen Sicherheit und Biomarker-Signatur zur Überwachung der Nierenfunktion
WO2008122670A2 (en) 2007-04-10 2008-10-16 Integragen Human diabetes susceptibility tnfrsf10b gene
US8080394B2 (en) * 2007-04-27 2011-12-20 Brigham And Women's Hospital Method for determining predisposition to pulmonary infection
US9091695B2 (en) * 2007-06-01 2015-07-28 Laboratory Corporation Of America Holdings Methods and systems for quantification of peptides and other analytes
US20100184110A1 (en) 2007-06-06 2010-07-22 Siemens Healthcare Diagnostics Inc. Predictive diagnostics for kidney disease
US20090047689A1 (en) * 2007-06-20 2009-02-19 John Kolman Autoantigen biomarkers for early diagnosis of lung adenocarcinoma
US20100267041A1 (en) * 2007-09-14 2010-10-21 Predictive Biosciences, Inc. Serial analysis of biomarkers for disease diagnosis
WO2009038742A2 (en) 2007-09-20 2009-03-26 Caritas St. Elizabeth's Medical Center Of Boston, Inc. Method for estimating risk of acute kidney injury
US8039227B2 (en) * 2007-09-20 2011-10-18 University Of Louisville Research Foundation, Inc. Peptide biomarkers predictive of renal function decline and kidney disease
US8003333B2 (en) * 2007-09-28 2011-08-23 Mayo Foundation For Medical Education And Research Serum biomarkers for early detection of acute cellular rejection
US20110111427A1 (en) 2008-02-29 2011-05-12 Kenji Kadomatsu Biomarker for the estimation of acute renal disorder and prognosis of the disorder, and use of the biomarker
US20090298106A1 (en) * 2008-05-30 2009-12-03 Therapeutic Monitoring Services, L.L.C. Methods for Monitoring Immunosuppressant Drug Levels, Renal Function, and Hepatic Function Using Small Volume Samples
US8241861B1 (en) * 2008-07-08 2012-08-14 Insilicos, Llc Methods and compositions for diagnosis or prognosis of cardiovascular disease
EP2149613A1 (de) * 2008-07-28 2010-02-03 Greenwood Genetic Center, Inc. Verfahren zur Bestimmung der Dysregulierung der Methylation von hirnexprimierten Genen auf dem X-Chromosom zur Diagnose von autistischen Spektrumsstörungen
WO2010022210A2 (en) * 2008-08-21 2010-02-25 Pxbiosciences Llc Diagnosis and monitoring of renal failure using peptide biomarkers
NZ591437A (en) 2008-08-28 2013-07-26 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP5947544B2 (ja) 2008-08-29 2016-07-06 アスチュート メディカル，インコーポレイテッド 腎損傷および腎不全の診断および予後のための方法および組成物
US8501489B2 (en) * 2008-09-26 2013-08-06 University of Pittsburgh—of the Commonwealth System of Higher Education Urinary biomarkers to predict long-term dialysis
CA2740923A1 (en) 2008-10-21 2010-04-29 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
ES2836218T3 (es) * 2008-10-21 2021-06-24 Astute Medical Inc Procedimientos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal
EP2913676A1 (de) 2008-11-10 2015-09-02 Astute Medical, Inc. Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz
US9229010B2 (en) * 2009-02-06 2016-01-05 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CA2751435A1 (en) 2009-02-06 2010-08-12 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and failure
EP2427496A4 (de) 2009-04-03 2013-05-15 Vegenics Pty Ltd Antikörper gegen vegf-d
WO2010128158A1 (en) 2009-05-08 2010-11-11 Novartis Ag Diagnostic biomarkers for fibrotic disorders
WO2011017684A1 (en) * 2009-08-07 2011-02-10 Rules-Based Medicine, Inc. Methods and devices for detecting diabetic nephropathy and associated disorders
EP2480882A4 (de) 2009-09-21 2013-07-10 Astute Medical Inc Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
CA2784889C (en) 2009-12-20 2018-06-19 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US20130035290A1 (en) * 2011-05-17 2013-02-07 Yale University Chitinase-3-Like Protein 1 as a Biomarker of Recovery from Kidney Injury

Also Published As

Publication number Publication date
EP2324355A1 (de) 2011-05-25
HK1213320A1 (zh) 2016-06-30
US20230020055A1 (en) 2023-01-19
JP2012501456A (ja) 2012-01-19
MX2011002233A (es) 2011-09-27
US11150250B2 (en) 2021-10-19
AU2009285550B2 (en) 2015-06-18
CN105067819A (zh) 2015-11-18
MX341926B (es) 2016-09-07
US20110195429A1 (en) 2011-08-11
NZ591437A (en) 2013-07-26
KR20110073471A (ko) 2011-06-29
WO2010025424A1 (en) 2010-03-04
BRPI0917711A2 (pt) 2017-06-20
CA2735587A1 (en) 2010-03-04
EP2743702B1 (de) 2017-08-09
EP2743702A3 (de) 2014-09-17
JP6126186B2 (ja) 2017-05-10
EP2324355B1 (de) 2014-01-22
NZ610356A (en) 2015-03-27
CN102187220A (zh) 2011-09-14
EP3273246A1 (de) 2018-01-24
CN102187220B (zh) 2015-08-19
CN105067819B (zh) 2018-05-22
HK1198391A1 (en) 2015-04-17
AU2009285550A1 (en) 2010-03-04
JP2016048242A (ja) 2016-04-07
EP2743702A2 (de) 2014-06-18
EP2324355A4 (de) 2011-11-23

Similar Documents

Publication Publication Date Title
HK1212776A1 (zh) 用於診斷和預後腎損傷和腎衰竭的方法和組合物
HK1213320A1 (zh) 用於診斷和預後腎損傷和腎衰竭的方法和組合物
HK1203619A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1199929A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1199931A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1211082A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1159755A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2480882A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
HK1208074A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1167455A1 (zh) 用於腎損傷和腎衰竭的診斷及預後方法和組合物
HK1214864A1 (zh) 用於腎損傷和腎衰竭的診斷及預後的方法和組合物
EP2539712A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
HK1200218A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2531620A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
HK1167888A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1211084A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1212774A1 (zh) 用於腎損傷和腎衰竭的診斷及預後方法和組合物
EP2462446A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
EP2531622A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
EP2585825A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
EP2531621A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
EP2593794A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
HK1197298A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180823