HK1118577A1 - Rnai expression constructs rnai - Google Patents
Rnai expression constructs rnaiInfo
- Publication number
- HK1118577A1 HK1118577A1 HK08112495.7A HK08112495A HK1118577A1 HK 1118577 A1 HK1118577 A1 HK 1118577A1 HK 08112495 A HK08112495 A HK 08112495A HK 1118577 A1 HK1118577 A1 HK 1118577A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- rnai
- expression constructs
- organs
- genes
- disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/51—Physical structure in polymeric form, e.g. multimers, concatemers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
- C12N2310/531—Stem-loop; Hairpin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/30—Production chemically synthesised
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64964105P | 2005-02-03 | 2005-02-03 | |
US65358005P | 2005-02-15 | 2005-02-15 | |
PCT/US2006/004003 WO2006084209A2 (fr) | 2005-02-03 | 2006-02-03 | Produits de synthese d'expression d'arni |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1118577A1 true HK1118577A1 (en) | 2009-02-13 |
Family
ID=36603389
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK08112495.7A HK1118577A1 (en) | 2005-02-03 | 2008-11-14 | Rnai expression constructs rnai |
Country Status (10)
Country | Link |
---|---|
US (4) | US8076471B2 (fr) |
EP (2) | EP1844145A2 (fr) |
CN (1) | CN101180394B (fr) |
AU (1) | AU2006210443B2 (fr) |
CA (1) | CA2596711C (fr) |
DK (1) | DK2172549T3 (fr) |
HK (1) | HK1118577A1 (fr) |
IL (1) | IL185315A0 (fr) |
NZ (1) | NZ560936A (fr) |
WO (1) | WO2006084209A2 (fr) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ560936A (en) | 2005-02-03 | 2010-04-30 | Benitec Inc | RNAI expression constructs |
GB0708662D0 (en) * | 2007-05-04 | 2007-06-13 | Galapagos Nv | shRNA sequences |
EP2173900A4 (fr) * | 2007-06-22 | 2010-12-29 | Alnylam Pharmaceuticals Inc | Molécules effectrices d'arn double brin d'hépatite c, constructions d'expression, compositions, et procédés d'utilisation |
US9217155B2 (en) | 2008-05-28 | 2015-12-22 | University Of Massachusetts | Isolation of novel AAV'S and uses thereof |
US8435790B2 (en) * | 2008-07-25 | 2013-05-07 | The Regents Of The University Of California | Methods of modulating lipid concentrations in eukaryotic cells |
US8734809B2 (en) | 2009-05-28 | 2014-05-27 | University Of Massachusetts | AAV's and uses thereof |
US9200276B2 (en) | 2009-06-01 | 2015-12-01 | Halo-Bio Rnai Therapeutics, Inc. | Polynucleotides for multivalent RNA interference, compositions and methods of use thereof |
AU2011223820B2 (en) | 2010-03-01 | 2016-01-14 | The Children's Hospital Of Philadelphia | Nucleic acids for targeting multiple regions of the HCV genome |
ES2631458T3 (es) | 2010-03-04 | 2017-08-31 | Interna Technologies B.V. | Molécula de ARNmi definida por su fuente y sus usos terapéuticos en el cáncer asociado a la EMT |
CA2833912C (fr) | 2010-04-23 | 2021-09-21 | University Of Massachusetts | Traitement a base d'aav pour des troubles lies au cholesterol |
US9546369B2 (en) | 2010-04-23 | 2017-01-17 | University Of Massachusetts | Multicistronic expression constructs |
ES2698203T3 (es) | 2010-04-23 | 2019-02-01 | Univ Massachusetts | Vectores de AAV que se dirigen al SNC y métodos de uso de los mismos |
NZ704322A (en) | 2010-07-06 | 2016-07-29 | Interna Technologies Bv | Mirna and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated braf pathway |
CA2853613C (fr) | 2010-10-28 | 2020-03-24 | Benitec Biopharma Limited | Traitement d'une infection par le vhb |
EP2474617A1 (fr) | 2011-01-11 | 2012-07-11 | InteRNA Technologies BV | MIR pour traiter une nouvelle angiogenèse |
US9226936B2 (en) | 2011-10-28 | 2016-01-05 | The Wistar of Anatomy and Biology | Methods and compositions for enhancing the therapeutic effect of anti-tumor T cells |
US10238755B2 (en) | 2011-11-30 | 2019-03-26 | The Wistar Institute Of Anatomy And Biology | Methods and compositions for regulation of cell aging, carcinogenesis and reprogramming |
EP2794881B1 (fr) | 2011-12-22 | 2018-06-27 | InteRNA Technologies B.V. | Miarn pour le traitement du cancer de la tête et du cou |
EP2917348A1 (fr) | 2012-11-06 | 2015-09-16 | InteRNA Technologies B.V. | Association médicamenteuse utilisable en vue du traitement de maladies ou d'affections associées au mélanome ou à l'activation de la voie de signalisation braf |
EP2943571A4 (fr) * | 2013-01-08 | 2016-11-30 | Benitec Biopharma Ltd | Traitement de la dégénérescence maculaire liée à l'âge |
KR20170045347A (ko) | 2014-09-07 | 2017-04-26 | 셀렉타 바이오사이언시즈, 인크. | 엑손 스키핑 항-바이러스 전달 벡터 면역 반응을 약화시키기 위한 방법 및 조성물 |
ES2870607T3 (es) | 2014-10-02 | 2021-10-27 | Wistar Inst | Métodos y composiciones para tratar cáncer |
WO2016065001A1 (fr) | 2014-10-21 | 2016-04-28 | University Of Massachusetts | Variants de vaa recombinants et leurs utilisations |
CN112410338A (zh) | 2014-11-14 | 2021-02-26 | 沃雅戈治疗公司 | 调节性多核苷酸 |
RU2020108189A (ru) | 2014-11-14 | 2020-03-11 | Вояджер Терапьютикс, Инк. | Композиции и способы лечения бокового амиотрофического склероза (als) |
JP2018525037A (ja) | 2015-08-24 | 2018-09-06 | ハロー−バイオ・アールエヌエーアイ・セラピューティックス、インコーポレイテッド | 遺伝子発現の調節のためのポリヌクレオチドナノ粒子及びその使用 |
EP3356531A4 (fr) * | 2015-10-01 | 2019-05-29 | Apse Llc | Procédés et compositions comprenant des noeuds apse |
EP3416668A4 (fr) | 2016-02-18 | 2020-02-19 | The Wistar Institute Of Anatomy And Biology | Méthodes et compositions pour le traitement du mélanome |
CA3024449A1 (fr) | 2016-05-18 | 2017-11-23 | Voyager Therapeutics, Inc. | Compositions et methodes de traitement de la maladie de huntington |
KR20240056729A (ko) | 2016-05-18 | 2024-04-30 | 보이저 테라퓨틱스, 인크. | 조절성 폴리뉴클레오티드 |
AU2017341849B2 (en) | 2016-10-13 | 2024-03-21 | University Of Massachusetts | AAV capsid designs |
CA3061652A1 (fr) | 2017-05-05 | 2018-11-08 | Voyager Therapeutics, Inc. | Compositions et methodes de traitement de la sclerose laterale amyotrophique (sla) |
MX2019013172A (es) | 2017-05-05 | 2020-09-07 | Voyager Therapeutics Inc | Composiciones y metodos para tratar la enfermedad de huntington. |
US20190142974A1 (en) | 2017-10-13 | 2019-05-16 | Selecta Biosciences, Inc. | Methods and compositions for attenuating anti-viral transfer vector igm responses |
US20200237799A1 (en) | 2017-10-16 | 2020-07-30 | Voyager Therapeutics, Inc. | Treatment of amyotrophic lateral sclerosis (als) |
TWI804518B (zh) | 2017-10-16 | 2023-06-11 | 美商航海家醫療公司 | 肌萎縮性脊髓側索硬化症(als)之治療 |
AU2018358016A1 (en) | 2017-11-03 | 2020-05-07 | Interna Technologies B.V. | MiRNA molecule, equivalent, antagomir, or source thereof for treating and/or diagnosing a condition and/or a disease associated with neuronal deficiency or for neuronal (re)generation |
AU2020284555A1 (en) | 2019-05-28 | 2021-12-23 | Selecta Biosciences, Inc. | Methods and compositions for attenuated anti-viral transfer vector immune response |
CN111454955B (zh) * | 2020-04-27 | 2023-05-12 | 广西壮族自治区林业科学研究院 | 源于尾叶桉CAD基因序列的RNAi片段及其应用 |
WO2023064367A1 (fr) | 2021-10-12 | 2023-04-20 | Selecta Biosciences, Inc. | Méthodes et compositions permettant d'atténuer les réponses anti-igm de vecteur de transfert viral |
US20230357437A1 (en) | 2022-03-09 | 2023-11-09 | Selecta Biosciences, Inc. | Immunosuppressants in combination with anti-igm agents and related dosing |
GB202208347D0 (en) | 2022-06-07 | 2022-07-20 | Univ Court Univ Of Glasgow | Targets for cancer therapy |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6218181B1 (en) | 1998-03-18 | 2001-04-17 | The Salk Institute For Biological Studies | Retroviral packaging cell line |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
US6509323B1 (en) | 1998-07-01 | 2003-01-21 | California Institute Of Technology | Linear cyclodextrin copolymers |
EP1192455B1 (fr) * | 1999-06-08 | 2014-07-02 | Broadley Technologies Corporation | Electrode de réference avec jonction d'écoulement liquide microfluidique |
US6487450B1 (en) * | 2000-02-24 | 2002-11-26 | Cedars-Sinai Medical Center | System and method for preventing Sudden Cardiac Death by nerve sprouting from right stellate ganglion |
IL151781A0 (en) | 2000-03-16 | 2003-04-10 | Genetica Inc | Methods and compositions for rna interference |
US20020162128A1 (en) * | 2000-04-19 | 2002-10-31 | Akemichi Baba | Non-human animal deficient in function of pituitary adenylate cyclase-activating polypeptide gene |
JP4344858B2 (ja) | 2001-09-13 | 2009-10-14 | カリフォルニア インスティチュート オブ テクノロジー | 細胞内で抗ウイルス性小rna分子を発現させる方法 |
US6758254B2 (en) * | 2001-10-16 | 2004-07-06 | Nautilus Systems, Inc. | Method and apparatus for removing and applying adhesive components |
CA2457528C (fr) * | 2002-02-20 | 2011-07-12 | Sirna Therapeutics, Inc. | Inhibition a mediation par interference arn de l'expression du gene du virus de l'hepatite c (vhc) au moyen d'acide nucleique interferent court (sina) |
DE10212892A1 (de) * | 2002-03-20 | 2003-10-09 | Basf Plant Science Gmbh | Konstrukte und Verfahren zur Regulation der Genexpression |
US20040053876A1 (en) * | 2002-03-26 | 2004-03-18 | The Regents Of The University Of Michigan | siRNAs and uses therof |
DE60326961D1 (de) * | 2002-07-26 | 2009-05-14 | Novartis Vaccines & Diagnostic | Modifizierte kleine irns moleküle und methoden zu deren anwendung |
RU2005106999A (ru) | 2002-08-29 | 2005-08-27 | Дзе Борд Оф Трастиз Оф Дзе Лелэнд Стэнфорд Джуниор Юниверсити (Us) | Кольцевые векторы нуклеиновой кислоты и способы их создания и использования |
KR20050084607A (ko) * | 2002-09-28 | 2005-08-26 | 매사추세츠 인스티튜트 오브 테크놀로지 | 인플루엔자 치료제 |
WO2004078974A1 (fr) | 2003-01-24 | 2004-09-16 | Tokyo Metropolitan Organization For Medical Research | Oligoribonucleotide ou acide nucleique peptidique inhibant la fonction du virus de l'hepatite c |
WO2004085623A2 (fr) | 2003-03-24 | 2004-10-07 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Vecteur d'expression de synthese compact comprenant des molecules d'adn double brin et methodes d'utilisation de ce vecteur |
WO2004106517A1 (fr) * | 2003-06-03 | 2004-12-09 | Benitec Australia Limited | Acide nucleique double brin |
CN1276086C (zh) * | 2003-08-13 | 2006-09-20 | 复旦大学 | 一类双链rna分子及其在制备抑制乙型肝炎病毒复制药物中的应用 |
US20050087926A1 (en) * | 2003-09-26 | 2005-04-28 | Aruze Corporation | Gaming machine |
KR101246862B1 (ko) * | 2004-03-05 | 2013-03-27 | 베니텍 리미티드 | RNAi 제제의 동시 전달을 위한 다중 프로모터 발현카세트 |
NZ560936A (en) | 2005-02-03 | 2010-04-30 | Benitec Inc | RNAI expression constructs |
-
2006
- 2006-02-03 NZ NZ560936A patent/NZ560936A/en unknown
- 2006-02-03 US US11/883,645 patent/US8076471B2/en not_active Expired - Fee Related
- 2006-02-03 WO PCT/US2006/004003 patent/WO2006084209A2/fr active Application Filing
- 2006-02-03 EP EP06734372A patent/EP1844145A2/fr not_active Withdrawn
- 2006-02-03 EP EP09015950.0A patent/EP2172549B1/fr not_active Not-in-force
- 2006-02-03 DK DK09015950.0T patent/DK2172549T3/en active
- 2006-02-03 AU AU2006210443A patent/AU2006210443B2/en not_active Ceased
- 2006-02-03 CN CN2006800108113A patent/CN101180394B/zh not_active Expired - Fee Related
- 2006-02-03 CA CA2596711A patent/CA2596711C/fr not_active Expired - Fee Related
- 2006-02-03 US US11/347,028 patent/US7803611B2/en not_active Expired - Fee Related
-
2007
- 2007-08-16 IL IL185315A patent/IL185315A0/en unknown
-
2008
- 2008-11-14 HK HK08112495.7A patent/HK1118577A1/xx not_active IP Right Cessation
-
2011
- 2011-11-10 US US13/293,359 patent/US8993530B2/en not_active Expired - Fee Related
-
2015
- 2015-03-30 US US14/673,468 patent/US20150197751A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
NZ560936A (en) | 2010-04-30 |
EP1844145A2 (fr) | 2007-10-17 |
US20120058555A1 (en) | 2012-03-08 |
US8993530B2 (en) | 2015-03-31 |
EP2172549B1 (fr) | 2015-08-26 |
US20070025969A1 (en) | 2007-02-01 |
IL185315A0 (en) | 2008-02-09 |
CN101180394B (zh) | 2013-01-09 |
US20150197751A1 (en) | 2015-07-16 |
AU2006210443B2 (en) | 2011-01-27 |
CN101180394A (zh) | 2008-05-14 |
WO2006084209A3 (fr) | 2007-03-08 |
EP2172549A3 (fr) | 2010-07-07 |
EP2172549A2 (fr) | 2010-04-07 |
CA2596711A1 (fr) | 2006-08-10 |
US20100028998A1 (en) | 2010-02-04 |
AU2006210443A1 (en) | 2006-08-10 |
CA2596711C (fr) | 2015-12-15 |
US8076471B2 (en) | 2011-12-13 |
WO2006084209A2 (fr) | 2006-08-10 |
DK2172549T3 (en) | 2015-11-02 |
US7803611B2 (en) | 2010-09-28 |
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