JPS5990947A
(ja)
*
|
1982-11-16 |
1984-05-25 |
Matsushita Electronics Corp |
半導体装置
|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
US20040141983A1
(en)
*
|
1999-03-15 |
2004-07-22 |
Protein Design Labs, Inc. |
Compositions against cancer antigen LIV-1 and uses thereof
|
US7244827B2
(en)
|
2000-04-12 |
2007-07-17 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer
|
US7358353B2
(en)
|
2000-08-22 |
2008-04-15 |
Agensys, Inc. |
Nucleic acid and corresponding protein named 158P1D7 useful in the treatment and detection of bladder and other cancers
|
US20040018194A1
(en)
*
|
2000-11-28 |
2004-01-29 |
Francisco Joseph A. |
Recombinant anti-CD30 antibodies and uses thereof
|
US7256257B2
(en)
|
2001-04-30 |
2007-08-14 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
WO2002092771A2
(en)
|
2001-05-11 |
2002-11-21 |
Ludwig Institute For Cancer Research |
Specific binding proteins and uses thereof
|
US20100056762A1
(en)
|
2001-05-11 |
2010-03-04 |
Old Lloyd J |
Specific binding proteins and uses thereof
|
US20110313230A1
(en)
|
2001-05-11 |
2011-12-22 |
Terrance Grant Johns |
Specific binding proteins and uses thereof
|
US20050272120A1
(en)
*
|
2001-06-20 |
2005-12-08 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
US20110045005A1
(en)
|
2001-10-19 |
2011-02-24 |
Craig Crowley |
Compositions and methods for the treatment of tumor of hematopoietic origin
|
US20050215472A1
(en)
|
2001-10-23 |
2005-09-29 |
Psma Development Company, Llc |
PSMA formulations and uses thereof
|
SG108837A1
(en)
|
2002-03-11 |
2005-02-28 |
Pi Eta Consulting Co Pte Ltd |
An enterprise knowledge and information acquisition, management and communications system with intelligent user interfaces
|
US20090068178A1
(en)
*
|
2002-05-08 |
2009-03-12 |
Genentech, Inc. |
Compositions and Methods for the Treatment of Tumor of Hematopoietic Origin
|
EP1545613B9
(en)
*
|
2002-07-31 |
2012-01-25 |
Seattle Genetics, Inc. |
Auristatin conjugates and their use for treating cancer, an autoimmune disease or an infectious disease
|
US20040081653A1
(en)
*
|
2002-08-16 |
2004-04-29 |
Raitano Arthur B. |
Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer
|
WO2004067564A2
(en)
*
|
2003-01-29 |
2004-08-12 |
Protein Design Labs, Inc. |
Compositions against cancer antigen liv-1 and uses thereof
|
JP5356648B2
(ja)
|
2003-02-20 |
2013-12-04 |
シアトル ジェネティックス, インコーポレイテッド |
抗cd70抗体−医薬結合体、ならびに癌および免疫障害の処置のためのそれらの使用
|
US20080025989A1
(en)
|
2003-02-20 |
2008-01-31 |
Seattle Genetics, Inc. |
Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
|
WO2011008992A2
(en)
|
2009-07-15 |
2011-01-20 |
The Regents Of The University Of California |
Peptides whose uptake in cells is controllable
|
US7985401B2
(en)
|
2003-10-31 |
2011-07-26 |
The Regents Of The University Of California |
Peptides whose uptake by cells is controllable
|
SI2489364T1
(sl)
|
2003-11-06 |
2015-04-30 |
Seattle Genetics, Inc. |
Monometilvalinske spojine, konjugirane s protitelesi
|
US20050175619A1
(en)
*
|
2004-02-05 |
2005-08-11 |
Robert Duffy |
Methods of producing antibody conjugates
|
WO2005082023A2
(en)
*
|
2004-02-23 |
2005-09-09 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
EP1725586B1
(en)
*
|
2004-03-02 |
2015-01-14 |
Seattle Genetics, Inc. |
Partially loaded antibodies and methods of their conjugation
|
AU2004319915B9
(en)
|
2004-04-22 |
2011-12-22 |
Agensys, Inc. |
Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
|
EP3088004B1
(en)
|
2004-09-23 |
2018-03-28 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
US20060073152A1
(en)
*
|
2004-10-05 |
2006-04-06 |
Genentech, Inc. |
Therapeutic agents with decreased toxicity
|
US7491390B2
(en)
|
2004-10-15 |
2009-02-17 |
Seattle Genetics, Inc. |
Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
|
US7641903B2
(en)
*
|
2004-10-15 |
2010-01-05 |
Seattle Genetics, Inc. |
Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
|
US8337838B2
(en)
*
|
2004-10-15 |
2012-12-25 |
Seattle Genetics, Inc. |
Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
|
AU2005332660A1
(en)
|
2004-11-12 |
2006-12-14 |
Seattle Genetics, Inc. |
Auristatins having an aminobenzoic acid unit at the N terminus
|
JP4993645B2
(ja)
|
2004-12-01 |
2012-08-08 |
ジェネンテック, インコーポレイテッド |
抗体薬剤結合体および方法
|
AU2006210837B2
(en)
*
|
2005-01-31 |
2012-07-12 |
Genentech, Inc. |
Anti-EphB2 antibodies and methods using same
|
US8759490B2
(en)
|
2005-03-24 |
2014-06-24 |
Millennium Pharamaceuticals, Inc. |
Antibodies that bind OV064 and methods of use therefor
|
EP2384767B1
(en)
*
|
2005-03-24 |
2016-03-09 |
Millennium Pharmaceuticals, Inc. |
Antibodies that bind OV064 and methods of use therefor
|
US8067546B2
(en)
|
2005-04-19 |
2011-11-29 |
Seattle Genetics, Inc. |
Humanized anti-CD70 binding agents and uses thereof
|
KR20140084242A
(ko)
*
|
2005-06-20 |
2014-07-04 |
피에스엠에이 디벨롭먼트 캄파니, 엘엘씨 |
Psma 항체-약물 접합체
|
USRE47223E1
(en)
|
2005-06-20 |
2019-02-05 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
EP2135881B1
(en)
|
2005-06-20 |
2011-09-07 |
Genentech, Inc. |
Antibodies binding to the tumour associated antigen TAT10772 for the diagnosis and treatment of tumor
|
US20070003559A1
(en)
*
|
2005-07-01 |
2007-01-04 |
Wyeth |
Methods of determining pharmacokinetics of targeted therapies
|
JP5171621B2
(ja)
*
|
2005-07-07 |
2013-03-27 |
シアトル ジェネティックス, インコーポレイテッド |
フェニルアラニン側鎖修飾をc末端に有するモノメチルバリン化合物
|
WO2007008848A2
(en)
|
2005-07-07 |
2007-01-18 |
Seattle Genetics, Inc. |
Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus
|
SI3248613T1
(sl)
|
2005-07-18 |
2022-04-29 |
Seagen Inc. |
Konjugati beta-glukuronidni linker-zdravilo
|
WO2007027941A2
(en)
|
2005-08-31 |
2007-03-08 |
Abraxis Bioscience, Llc. |
Compositions and methods for preparation of poorly water soluble drugs with increased stability
|
CN104189905A
(zh)
|
2005-08-31 |
2014-12-10 |
阿布拉科斯生物科学有限公司 |
包含水难溶性药剂和抗微生物剂的组合物
|
CA2623652C
(en)
*
|
2005-09-26 |
2013-11-26 |
Medarex, Inc. |
Antibody-drug conjugates and methods of use
|
ES2527961T3
(es)
*
|
2005-09-26 |
2015-02-02 |
Medarex, L.L.C. |
Anticuerpos monoclonales humanos para CD70
|
WO2007100385A2
(en)
*
|
2005-10-31 |
2007-09-07 |
Genentech, Inc. |
Macrocyclic depsipeptide antibody-drug conjugates and methods
|
ES2547689T3
(es)
|
2005-12-02 |
2015-10-08 |
Genentech, Inc. |
Composiciones y métodos para el tratamiento de enfermedades y trastornos asociados con la señalización de citocinas que implican anticuerpos que se unen a IL-22 y a IL-22R
|
CA2630483C
(en)
*
|
2005-12-08 |
2015-05-19 |
Medarex, Inc. |
Human monoclonal antibodies to o8e
|
EP1806365A1
(en)
|
2006-01-05 |
2007-07-11 |
Boehringer Ingelheim International GmbH |
Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them
|
JP5368110B2
(ja)
|
2006-01-20 |
2013-12-18 |
ジェネンテック, インコーポレイテッド |
抗エフリンb2抗体とその使用方法
|
US7750116B1
(en)
*
|
2006-02-18 |
2010-07-06 |
Seattle Genetics, Inc. |
Antibody drug conjugate metabolites
|
AR059851A1
(es)
|
2006-03-16 |
2008-04-30 |
Genentech Inc |
Anticuerpos de la egfl7 y metodos de uso
|
AR059900A1
(es)
|
2006-03-17 |
2008-05-07 |
Genentech Inc |
Anticuerpos anti-tat226 e inmunoconjugados
|
JP2009531324A
(ja)
|
2006-03-20 |
2009-09-03 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
癌標的化のための操作された抗前立腺幹細胞抗原(psca)抗体
|
CN103030696B
(zh)
|
2006-05-30 |
2016-09-28 |
健泰科生物技术公司 |
抗体和免疫偶联物及其用途
|
WO2008033782A2
(en)
|
2006-09-12 |
2008-03-20 |
Genentech, Inc. |
Methods and compositions for the diagnosis and treatment of lung cancer using pdgfra, kit or kdr gene as genetic marker
|
CA2667019C
(en)
*
|
2006-10-27 |
2016-03-29 |
Genentech, Inc. |
Antibodies and immunoconjugates and uses therefor
|
US8455622B2
(en)
|
2006-12-01 |
2013-06-04 |
Seattle Genetics, Inc. |
Variant target binding agents and uses thereof
|
MX2009006277A
(es)
*
|
2006-12-14 |
2009-07-24 |
Medarex Inc |
Anticuerpos humanos que se enlazan a cd70 y usos de los mismos.
|
US9090693B2
(en)
|
2007-01-25 |
2015-07-28 |
Dana-Farber Cancer Institute |
Use of anti-EGFR antibodies in treatment of EGFR mutant mediated disease
|
WO2008100805A2
(en)
|
2007-02-09 |
2008-08-21 |
Genentech, Inc. |
Anti-robo4 antibodies and uses therefor
|
JP5618549B2
(ja)
|
2007-03-15 |
2014-11-05 |
ルードヴィッヒ インスティテュート フォー キャンサーリサーチ リミテッド |
Egfr抗体及びsrc阻害剤を用いる治療方法及び関連製剤
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
WO2008118970A2
(en)
|
2007-03-27 |
2008-10-02 |
Sea Lane Biotechnologies, Llc |
Constructs and libraries comprising antibody surrogate light chain sequences
|
CN101687037B
(zh)
*
|
2007-05-08 |
2013-07-10 |
健泰科生物技术公司 |
半胱氨酸改造的抗muc16抗体和抗体药物偶联物
|
TWI439286B
(zh)
|
2007-07-16 |
2014-06-01 |
Genentech Inc |
抗-cd79b抗體及免疫共軛物及使用方法
|
UA103004C2
(ru)
|
2007-07-16 |
2013-09-10 |
Дженентек, Інк. |
Гуманизированное антитело против cd79b и иммуноконъюгаты и способы применения
|
ES2609915T3
(es)
|
2007-08-14 |
2017-04-25 |
Ludwig Institute For Cancer Research Ltd. |
Anticuerpo monoclonal 175 direccionado al receptor de EGF y derivados y usos del mismo
|
EP2197491A4
(en)
|
2007-09-04 |
2011-01-12 |
Univ California |
HIGHAFFINE ANTI-PROSTATE STEM CELL ANTIGEN (PSCA) ANTIBODIES TO CANCER AND TO THE DETECTION OF CANCER
|
CA2978687C
(en)
|
2007-09-26 |
2020-02-18 |
Chugai Seiyaku Kabushiki Kaisha |
Modified antibody constant region
|
CA2700410C
(en)
*
|
2007-10-03 |
2020-10-06 |
Cornell University |
Treatment of proliferative disorders using antibodies to psma
|
HUE031533T2
(hu)
*
|
2007-10-19 |
2017-07-28 |
Seattle Genetics Inc |
CD19-kötõszerek valamint alkalmazásuk
|
US8937161B2
(en)
*
|
2007-10-19 |
2015-01-20 |
Genentech, Inc. |
Cysteine engineered anti-TENB2 antibodies and antibody drug conjugates
|
JP5580205B2
(ja)
|
2007-11-19 |
2014-08-27 |
セレラ コーポレーション |
肺癌マーカーとその使用
|
JP2011509675A
(ja)
|
2008-01-18 |
2011-03-31 |
メディミューン,エルエルシー |
部位特異的コンジュゲーションのためのシステイン操作抗体
|
SG187517A1
(en)
|
2008-01-31 |
2013-02-28 |
Genentech Inc |
Anti-cd79b antibodies and immunoconjugates and methods of use
|
NO2842575T3
(el)
*
|
2008-03-18 |
2018-02-24 |
|
|
BRPI0906261A2
(pt)
*
|
2008-03-31 |
2015-07-07 |
Genentech Inc |
"métodos de diagnóstico de um subtipo de asma em uma amostra de paciente, usos de um agente terapêutico e kits de diagnóstico de um subtipo de asma em uma amostra de paciente"
|
CN102076865B
(zh)
|
2008-05-02 |
2016-03-16 |
西雅图基因公司 |
用于制造核心岩藻糖基化降低的抗体和抗体衍生物的方法和组合物
|
EP2318832B1
(en)
|
2008-07-15 |
2013-10-09 |
Academia Sinica |
Glycan arrays on ptfe-like aluminum coated glass slides and related methods
|
CA2727915C
(en)
|
2008-07-15 |
2016-04-26 |
Genentech, Inc. |
Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
|
US20100069616A1
(en)
*
|
2008-08-06 |
2010-03-18 |
The Regents Of The University Of California |
Engineered antibody-nanoparticle conjugates
|
EP2727606A3
(en)
|
2008-09-08 |
2015-09-23 |
Psma Development Company, L.L.C. |
Compounds for killing psma-expressing, taxane-resistant cancer cells
|
UA109633C2
(uk)
|
2008-12-09 |
2015-09-25 |
|
Антитіло людини проти тканинного фактора
|
WO2010081004A1
(en)
|
2009-01-09 |
2010-07-15 |
Seattle Genetics, Inc. |
Weekly dosing regimens for anti-cd30 vc-pab-mmae antibody drug-conjugates
|
WO2010083104A2
(en)
*
|
2009-01-13 |
2010-07-22 |
Emory University |
Conjugates of noscapine and folic acid and their use in treating cancer
|
ES2712732T3
(es)
*
|
2009-02-17 |
2019-05-14 |
Cornell Res Foundation Inc |
Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico
|
US9238878B2
(en)
*
|
2009-02-17 |
2016-01-19 |
Redwood Bioscience, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
BRPI1013645A2
(pt)
*
|
2009-03-06 |
2019-07-02 |
Agensys Inc |
conjugado de fármaco anticorpo e sua composição farmacêutica
|
SG174515A1
(en)
|
2009-03-25 |
2011-10-28 |
Genentech Inc |
NOVEL ANTI-a5ß1 ANTIBODIES AND USES THEREOF
|
KR101822663B1
(ko)
|
2009-03-25 |
2018-01-29 |
제넨테크, 인크. |
항-fgfr3 항체 및 그의 사용 방법
|
CA2757382A1
(en)
|
2009-04-01 |
2010-10-21 |
Kristi Elkins |
Anti-fcrh5 antibodies and immunoconjugates
|
AU2010232682A1
(en)
|
2009-04-01 |
2011-11-10 |
Genentech, Inc. |
Anti-FcRH5 antibodies and immunoconjugates and methods of use
|
PE20120591A1
(es)
|
2009-04-02 |
2012-05-23 |
Roche Glycart Ag |
Anticuerpos multiespecificos que comprenden anticuerpos de longitud completa y fragmentos fab de cadena sencilla
|
US8722860B2
(en)
|
2009-04-16 |
2014-05-13 |
Abbvie Biotherapeutics Inc. |
Anti-TNF-α antibodies and their uses
|
US20120128671A1
(en)
|
2009-05-13 |
2012-05-24 |
Lawrence Horowitz |
Neutralizing molecules to influenza viruses
|
KR20180056805A
(ko)
|
2009-06-04 |
2018-05-29 |
노파르티스 아게 |
IgG 콘쥬게이션을 위한 자리의 확인 방법
|
TWI510248B
(zh)
|
2009-06-17 |
2015-12-01 |
Abbvie Biotherapeutics Inc |
抗-vegf抗體及其用途
|
CA2766405A1
(en)
|
2009-06-22 |
2011-01-13 |
Medimmune, Llc |
Engineered fc regions for site-specific conjugation
|
WO2011015920A2
(en)
*
|
2009-08-03 |
2011-02-10 |
Avesthagen Limited |
A highly efficient process of purification and production of recombinant trastuzumab
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
WO2011034605A2
(en)
|
2009-09-16 |
2011-03-24 |
Genentech, Inc. |
Coiled coil and/or tether containing protein complexes and uses thereof
|
EP2477629B1
(en)
*
|
2009-09-17 |
2016-08-03 |
Vanderbilt University |
Substituted heteroarylamide analogs as mglur5 negative allosteric modulators and methods of making and using the same
|
WO2011038159A2
(en)
*
|
2009-09-24 |
2011-03-31 |
Seattle Genetics, Inc. |
Dr5 ligand drug conjugates
|
US20110076232A1
(en)
|
2009-09-29 |
2011-03-31 |
Ludwig Institute For Cancer Research |
Specific binding proteins and uses thereof
|
MY173390A
(en)
|
2009-10-23 |
2020-01-22 |
Takeda Pharmaceuticals Co |
Anti-gcc antibody molecules and related compositions and methods
|
EP2493929B1
(en)
|
2009-10-28 |
2017-08-16 |
AbbVie Biotherapeutics Inc. |
Anti-egfr antibodies and their uses
|
KR101884028B1
(ko)
|
2009-11-30 |
2018-08-01 |
제넨테크, 인크. |
Slc34a2 (tat211 = 서열 2)를 발현하는 종양의 치료 및 진단을 위한 항체
|
US11377485B2
(en)
|
2009-12-02 |
2022-07-05 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
EP3511023A1
(en)
|
2009-12-02 |
2019-07-17 |
Imaginab, Inc. |
J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use
|
RU2580038C2
(ru)
|
2009-12-04 |
2016-04-10 |
Дженентек, Инк. |
Мультиспецифические антитела, аналоги антител, композиции и способы
|
BR112012013717B1
(pt)
|
2009-12-10 |
2020-01-28 |
Hoffmann La Roche |
anticorpos de ligação ao csf-1r humano, composição farmacêutica e usos do anticorpo
|
WO2011084496A1
(en)
|
2009-12-16 |
2011-07-14 |
Abbott Biotherapeutics Corp. |
Anti-her2 antibodies and their uses
|
WO2011075185A1
(en)
|
2009-12-18 |
2011-06-23 |
Oligasis |
Targeted drug phosphorylcholine polymer conjugates
|
PL2516465T3
(pl)
|
2009-12-23 |
2016-11-30 |
|
Przeciwciała anty-bv8 i ich zastosowania
|
KR101510413B1
(ko)
|
2010-02-08 |
2015-04-08 |
어젠시스 인코포레이티드 |
161p2f10b 단백질에 결합하는 항체 약물 컨쥬게이트
|
JP5981853B2
(ja)
|
2010-02-18 |
2016-08-31 |
ジェネンテック, インコーポレイテッド |
ニューレグリンアンタゴニスト及び癌の治療におけるそれらの使用
|
NZ601293A
(en)
|
2010-02-23 |
2014-10-31 |
Genentech Inc |
Compositions and methods for the diagnosis and treatment of tumor
|
DK2542576T3
(en)
|
2010-03-02 |
2016-08-01 |
Seattle Genetics Inc |
METHODS OF SCREENING ANTIBODIES
|
MX2012010014A
(es)
|
2010-03-05 |
2012-09-21 |
Hoffmann La Roche |
Anticuerpos contra csf-1r humano y sus usos.
|
BR112012022046A2
(pt)
|
2010-03-05 |
2017-02-14 |
F Hoffamann-La Roche Ag |
''anticorpo,composição farmacêutica,ácido nucleico ,vetores de expressão,célula hospedeira e método para a produção de um anticorpo recombinante''.
|
US8642557B2
(en)
|
2010-03-12 |
2014-02-04 |
Abbvie Biotherapeutics Inc. |
CTLA4 proteins and their uses
|
TW201138823A
(en)
|
2010-03-24 |
2011-11-16 |
Genentech Inc |
Anti-LRP6 antibodies
|
TW201138821A
(en)
|
2010-03-26 |
2011-11-16 |
Roche Glycart Ag |
Bispecific antibodies
|
PT3178851T
(pt)
|
2010-03-31 |
2020-07-17 |
Boehringer Ingelheim Int |
Anticorpos anti-cd40
|
EP2552967A4
(en)
|
2010-04-02 |
2014-10-08 |
Amunix Operating Inc |
BINDING FUSION PROTEINS, BINDING FUSION PROTEIN MEDICINAL CONJUGATES, XTEN MEDICAMENT CONJUGATES, AND METHOD FOR THEIR PREPARATION AND USE
|
WO2011130332A1
(en)
|
2010-04-12 |
2011-10-20 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
WO2011130616A1
(en)
|
2010-04-15 |
2011-10-20 |
Spirogen Limited |
Pyrrolobenzodiazepines used to treat proliferative diseases
|
WO2011133886A2
(en)
|
2010-04-23 |
2011-10-27 |
Genentech, Inc. |
Production of heteromultimeric proteins
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
MX336109B
(es)
|
2010-06-03 |
2016-01-08 |
Genentech Inc |
Formacion de imagenes inmuno-tep de anticuerpos e inmunoconjugados y usos de lo mismo.
|
WO2011156328A1
(en)
|
2010-06-08 |
2011-12-15 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
JP6093696B2
(ja)
|
2010-06-09 |
2017-03-08 |
ゲンマブ エー/エス |
ヒトcd38に対する抗体
|
JP5791707B2
(ja)
|
2010-06-10 |
2015-10-07 |
シアトル ジェネティックス, インコーポレイテッド |
新規アウリスタチン誘導体およびその使用
|
AU2011267106B2
(en)
*
|
2010-06-15 |
2015-05-14 |
Genmab A/S |
Human antibody drug conjugates against tissue factor
|
EP2582729A4
(en)
|
2010-06-18 |
2014-05-28 |
Hoffmann La Roche |
ANTI-AXL ANTIBODIES AND METHOD FOR THEIR USE
|
WO2011161119A1
(en)
|
2010-06-22 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Antibodies against insulin-like growth factor i receptor and uses thereof
|
WO2011161189A1
(en)
|
2010-06-24 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Anti-hepsin antibodies and methods of use
|
CN103052649B
(zh)
|
2010-07-29 |
2015-12-16 |
Xencor公司 |
具有修改的等电点的抗体
|
JP2013541501A
(ja)
|
2010-08-03 |
2013-11-14 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
慢性リンパ性白血病(cll)のバイオマーカー
|
WO2012020006A2
(en)
|
2010-08-13 |
2012-02-16 |
Roche Glycart Ag |
Anti-fap antibodies and methods of use
|
EP2603529A1
(en)
|
2010-08-13 |
2013-06-19 |
Roche Glycart AG |
Anti-tenascin-c a2 antibodies and methods of use
|
EP2603525A1
(en)
|
2010-08-13 |
2013-06-19 |
F.Hoffmann-La Roche Ag |
Antibodies to il-1beta and il-18, for treatment of disease
|
CN103068846B9
(zh)
|
2010-08-24 |
2016-09-28 |
弗·哈夫曼-拉罗切有限公司 |
包含二硫键稳定性Fv片段的双特异性抗体
|
US20120089541A1
(en)
|
2010-08-31 |
2012-04-12 |
Genentech, Inc. |
Biomarkers and methods of treatment
|
LT2621526T
(lt)
|
2010-09-29 |
2018-09-25 |
Agensys, Inc. |
Antikūno-vaisto konjugatai (adc), kurie jungiasi prie 191p4d12 baltymų
|
EP2621508B1
(de)
|
2010-09-29 |
2015-08-26 |
Seattle Genetics, Inc. |
N-carboxyalkyl-auristatine und ihre verwendung
|
EP3828205A1
(en)
|
2010-10-01 |
2021-06-02 |
Oxford BioTherapeutics Ltd |
Anti-ror1 antibodies
|
EP2629801B3
(en)
|
2010-10-22 |
2019-11-27 |
Seattle Genetics, Inc. |
Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the pi3k-akt mtor pathway
|
JP6163429B2
(ja)
|
2010-11-10 |
2017-07-12 |
ジェネンテック, インコーポレイテッド |
神経疾患免疫治療のための方法及び組成物
|
EP2637692A4
(en)
|
2010-11-12 |
2014-09-10 |
Scott & White Healthcare |
ANTIBODIES TO THE ENDOTHELIAL TUMOR MARKER 8
|
BR112013013781A2
(pt)
|
2010-12-06 |
2016-09-13 |
Seattle Genetics Inc |
anticorpos humanizados para liv-1 e uso dos mesmos para tratar câncer
|
EP3447491A3
(en)
|
2010-12-16 |
2019-06-05 |
F. Hoffmann-La Roche AG |
Diagnosis and treatments relating to th2 inhibition
|
NZ610976A
(en)
*
|
2010-12-20 |
2015-07-31 |
Genentech Inc |
Anti-mesothelin antibodies and immunoconjugates
|
US20120195910A1
(en)
|
2010-12-22 |
2012-08-02 |
Genentech, Inc. |
Anti-pcsk9 antibodies and methods of use
|
WO2012085111A1
(en)
|
2010-12-23 |
2012-06-28 |
F. Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
JP6162606B2
(ja)
|
2011-01-14 |
2017-07-12 |
レッドウッド バイオサイエンス, インコーポレイテッド |
アルデヒド−タグ付き免疫グロブリンポリペプチド及びその使用方法
|
CN103649117B
(zh)
|
2011-02-04 |
2016-09-14 |
霍夫曼-拉罗奇有限公司 |
Fc变体及其生成方法
|
US10689447B2
(en)
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
CA2829736C
(en)
*
|
2011-03-16 |
2020-07-21 |
Seattle Genetics, Inc. |
N-carboxyalkylauristatins and use thereof
|
CA2828289C
(en)
|
2011-03-29 |
2020-07-21 |
Roche Glycart Ag |
Antibody fc variants
|
US9044518B2
(en)
|
2011-03-30 |
2015-06-02 |
Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University |
Auristatin tyramine phosphate salts and auristatin aminoquinoline derivatives and prodrugs thereof
|
KR101783529B1
(ko)
*
|
2011-04-01 |
2017-09-29 |
와이어쓰 엘엘씨 |
항체-약물 접합체
|
KR20140021589A
(ko)
|
2011-04-07 |
2014-02-20 |
제넨테크, 인크. |
항-fgfr4 항체 및 사용 방법
|
WO2012143523A1
(en)
|
2011-04-20 |
2012-10-26 |
Genmab A/S |
Bispecifc antibodies against her2
|
RU2013150331A
(ru)
|
2011-04-20 |
2015-05-27 |
Рош Гликарт Аг |
СПОСОБ И УСТРОЙСТВА ДЛЯ рН-ЗАВИСИМОГО ПРОХОЖДЕНИЯ ГЕМАТОЭНЦЕФАЛИЧЕСКОГО БАРЬЕРА
|
JP2014515753A
(ja)
|
2011-04-21 |
2014-07-03 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
新規な結合剤−薬物複合体(adc)およびそれらの使用
|
BR112013028907A2
(pt)
|
2011-05-08 |
2017-01-31 |
Legochem Biosciences Inc |
conjugados de proteína-agente ativo e método para preparar os mesmos
|
JP2014513692A
(ja)
|
2011-05-09 |
2014-06-05 |
ユニバーシティ オブ バージニア パテント ファウンデーション |
癌を治療するための組成物及び方法
|
RU2638806C2
(ru)
|
2011-05-12 |
2017-12-15 |
Дженентек, Инк. |
Lc-ms/ms способ мониторинга множественных реакций для выявления терапевтических антител в образцах животных с помощью каркасных сигнатурных пептидов
|
HUE033584T2
(hu)
|
2011-05-16 |
2017-12-28 |
Hoffmann La Roche |
FGFR1 agonisták és alkalmazási eljárások
|
US9790253B2
(en)
|
2011-05-19 |
2017-10-17 |
President And Fellows Of Harvard College |
OSW-1 analogs and conjugates, and uses thereof
|
WO2012162561A2
(en)
|
2011-05-24 |
2012-11-29 |
Zyngenia, Inc. |
Multivalent and monovalent multispecific complexes and their uses
|
CN106279418A
(zh)
|
2011-05-27 |
2017-01-04 |
葛兰素集团有限公司 |
Bcma(cd269/tnfrsf17)结合蛋白
|
UA112434C2
(uk)
|
2011-05-27 |
2016-09-12 |
Ґлаксо Ґруп Лімітед |
Антигензв'язувальний білок, який специфічно зв'язується з всма
|
WO2012166559A1
(en)
*
|
2011-05-27 |
2012-12-06 |
Ambrx, Inc. |
Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives
|
ES2690993T3
(es)
*
|
2011-05-27 |
2018-11-23 |
Ambrx, Inc. |
Composiciones que contienen y métodos que implican derivados de dolastatina enlazados con aminoácidos no naturales y usos de los mismos
|
CN103747804B
(zh)
|
2011-06-10 |
2016-08-17 |
梅尔莎纳医疗公司 |
蛋白质-聚合物-药物共轭物
|
US8815226B2
(en)
|
2011-06-10 |
2014-08-26 |
Mersana Therapeutics, Inc. |
Protein-polymer-drug conjugates
|
WO2012171987A1
(en)
*
|
2011-06-16 |
2012-12-20 |
Lonza Ltd |
A process for extraction of peptides and its application in liquid phase peptide synthesis
|
US9442092B2
(en)
|
2011-06-20 |
2016-09-13 |
Kerry Lane |
Methods for treatment of autism
|
AU2015224535B2
(en)
*
|
2011-06-21 |
2017-07-20 |
Immunogen, Inc. |
Novel maytansinoid derivatives with peptide linker and conjugates thereof
|
EA029797B1
(ru)
*
|
2011-06-21 |
2018-05-31 |
Иммуноджен, Инк. |
Новые производные майтанзиноида с пептидным линкером и их конъюгаты
|
EP2726098A1
(en)
|
2011-06-30 |
2014-05-07 |
F.Hoffmann-La Roche Ag |
Anti-c-met antibody formulations
|
UA117901C2
(uk)
|
2011-07-06 |
2018-10-25 |
Ґенмаб Б.В. |
Спосіб посилення ефекторної функції вихідного поліпептиду, його варіанти та їх застосування
|
WO2013015821A1
(en)
|
2011-07-22 |
2013-01-31 |
The Research Foundation Of State University Of New York |
Antibodies to the b12-transcobalamin receptor
|
US9120858B2
(en)
|
2011-07-22 |
2015-09-01 |
The Research Foundation Of State University Of New York |
Antibodies to the B12-transcobalamin receptor
|
EP2736928B1
(en)
|
2011-07-28 |
2019-01-09 |
i2 Pharmaceuticals, Inc. |
Sur-binding proteins against erbb3
|
CN103874512B
(zh)
|
2011-07-29 |
2016-11-16 |
艾维拉斯生物科学公司 |
选择性递送分子及使用方法
|
WO2013022855A1
(en)
|
2011-08-05 |
2013-02-14 |
Xencor, Inc. |
Antibodies with modified isoelectric points and immunofiltering
|
CN103890007A
(zh)
|
2011-08-17 |
2014-06-25 |
霍夫曼-拉罗奇有限公司 |
神经调节蛋白抗体及其用途
|
BR112014004166A2
(pt)
|
2011-08-23 |
2018-05-29 |
Roche Glycart Ag |
anticorpo biespecífico compreendendo pelo menos dois fragmentos fab, célula hospedeira procariótica ou eucariótica, metodo de produção de um anticorpo, imunoconjugado e invenção
|
BR112014004168A2
(pt)
|
2011-08-23 |
2017-12-12 |
Roche Glycart Ag |
anticorpo biespecífico, composição farmacêutica, uso do anticorpo biespecífico, célula hospedeira procariótica ou eucariótica, método de produção de anticorpo e invenção
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
UY34317A
(es)
|
2011-09-12 |
2013-02-28 |
Genzyme Corp |
Anticuerpo antireceptor de célula T (alfa)/ß
|
KR20140068062A
(ko)
|
2011-09-15 |
2014-06-05 |
제넨테크, 인크. |
분화의 촉진 방법
|
EP2758055A1
(en)
|
2011-09-19 |
2014-07-30 |
F.Hoffmann-La Roche Ag |
Combination treatments comprising c-met antagonists and b-raf antagonists
|
EP2751120B1
(en)
|
2011-09-20 |
2018-08-22 |
MedImmune Limited |
Pyrrolobenzodiazepines as unsymmetrical dimeric pbd compounds for inclusion in targeted conjugates
|
KR101684750B1
(ko)
|
2011-09-23 |
2016-12-08 |
로슈 글리카트 아게 |
이중특이적 항-egfr/항-igf-1r 항체
|
HUE043154T2
(hu)
|
2011-09-29 |
2019-08-28 |
Seattle Genetics Inc |
Proteinnel konjugált hatóanyag vegyületek intakt tömegének meghatározására
|
CA2849011A1
(en)
|
2011-10-05 |
2013-04-11 |
Genentech, Inc. |
Methods of treating liver conditions using notch2 antagonists
|
CA2851534C
(en)
|
2011-10-10 |
2023-02-14 |
Xencor, Inc. |
A method for purifying antibodies
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
EP3388435B1
(en)
|
2011-10-14 |
2023-05-03 |
Seagen Inc. |
Pyrrolobenzodiazepines and targeted conjugates
|
CN103974709B
(zh)
|
2011-10-14 |
2016-12-14 |
霍夫曼-拉罗奇有限公司 |
Bace1的肽抑制剂
|
CA2850032C
(en)
|
2011-10-14 |
2022-06-07 |
Genentech, Inc. |
Anti-htra1 antibodies and methods of use
|
BR112014008888A2
(pt)
|
2011-10-14 |
2017-04-18 |
Seattle Genetics Inc |
pirrolobenzodiazepinas
|
BR112014008981A2
(pt)
|
2011-10-14 |
2017-05-02 |
Spirogen Sàrl |
pirrolobenzodiazepinas
|
AU2012322613B2
(en)
|
2011-10-14 |
2016-04-21 |
Medimmune Limited |
Pyrrolobenzodiazepines and targeted conjugates
|
CA2850836A1
(en)
|
2011-10-15 |
2013-04-18 |
Genentech, Inc. |
Methods of using scd1 antagonists
|
EA201490879A1
(ru)
|
2011-10-28 |
2014-08-29 |
Дженентек, Инк. |
Терапевтические комбинации и способы лечения меланомы
|
WO2013068874A1
(en)
*
|
2011-11-11 |
2013-05-16 |
Pfizer Inc. |
Antibody-drug conjugates
|
SI2780039T1
(en)
*
|
2011-11-17 |
2018-06-29 |
Pfizer Inc. |
Cytotoxic peptides and their conjugates between the antibody and the drug
|
AU2015264844B2
(en)
*
|
2011-11-17 |
2016-09-01 |
Pfizer Inc. |
Cytotoxic peptides and antibody drug conjugates thereof
|
BR112014012005A2
(pt)
|
2011-11-21 |
2017-12-19 |
Genentech Inc |
composições, métodos, formulação farmacêutica e artigo
|
IN2014CN04961A
(el)
*
|
2011-12-05 |
2015-09-18 |
Igenica Biotherapeutics Inc |
|
BR112014014763A8
(pt)
*
|
2011-12-14 |
2017-07-04 |
Seattle Genetics Inc |
novos conjugados de anticorpo-medicamento (adcs) e uso dos mesmos
|
CA2853889A1
(en)
|
2011-12-15 |
2013-06-20 |
F. Hoffmann-La Roche Ag |
Antibodies against human csf-1r and uses thereof
|
EP3446707A1
(en)
|
2011-12-22 |
2019-02-27 |
i2 Pharmaceuticals, Inc. |
Surrogate binding proteins
|
AU2012356894B2
(en)
|
2011-12-23 |
2018-01-18 |
Innate Pharma |
Enzymatic conjugation of polypeptides
|
WO2013093809A1
(en)
|
2011-12-23 |
2013-06-27 |
Pfizer Inc. |
Engineered antibody constant regions for site-specific conjugation and methods and uses therefor
|
JP2015509091A
(ja)
|
2012-01-09 |
2015-03-26 |
ザ スクリプス リサーチ インスティテュート |
ヒト化抗体
|
EP2802603A4
(en)
|
2012-01-09 |
2015-11-04 |
Scripps Research Inst |
REGIONS DETERMINING ULTRALONGUAL COMPLEMENTARYITY AND USES THEREOF
|
BR112014017518A2
(pt)
|
2012-01-18 |
2018-09-04 |
Genentech Inc |
anticorpo e ácido nucleico isolados, célula hospedeira, métodos, imunoconjugado, formulação farmacêutica e uso do anticorpo
|
EP2804630B1
(en)
|
2012-01-18 |
2017-10-18 |
F. Hoffmann-La Roche AG |
Methods of using fgf19 modulators
|
JP2015505537A
(ja)
|
2012-01-20 |
2015-02-23 |
シー レーン バイオテクノロジーズ, エルエルシー |
結合分子コンジュゲート
|
CN104254778A
(zh)
|
2012-02-10 |
2014-12-31 |
西雅图遗传学公司 |
Cd30+癌症的检测和治疗
|
CA2861124A1
(en)
|
2012-02-10 |
2013-08-15 |
Genentech, Inc. |
Single-chain antibodies and other heteromultimers
|
AU2013216753B2
(en)
|
2012-02-11 |
2017-09-21 |
Genentech, Inc. |
R-spondin translocations and methods using the same
|
CN104125852B9
(zh)
|
2012-02-15 |
2017-05-17 |
弗·哈夫曼-拉罗切有限公司 |
基于Fc‑受体的亲和色谱
|
RU2582259C2
(ru)
|
2012-02-24 |
2016-04-20 |
Алтеоген Инк. |
Модифицированные антитела, с которыми связан мотив, включающий остаток цистеина, конъюгаты этих модифицированных антител с лекарственными веществами и способ их получения
|
EP2817339B1
(en)
|
2012-02-24 |
2019-05-15 |
AbbVie Stemcentrx LLC |
Anti sez6 antibodies and methods of use
|
ES2645272T3
(es)
|
2012-02-24 |
2017-12-04 |
Abbvie Stemcentrx Llc |
Moduladores de DLL3 y procedimientos de utilización
|
WO2013130093A1
(en)
|
2012-03-02 |
2013-09-06 |
Genentech, Inc. |
Biomarkers for treatment with anti-tubulin chemotherapeutic compounds
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
US20130280282A1
(en)
*
|
2012-04-24 |
2013-10-24 |
Daiichi Sankyo Co., Ltd. |
Dr5 ligand drug conjugates
|
US9156915B2
(en)
|
2012-04-26 |
2015-10-13 |
Thomas Jefferson University |
Anti-GCC antibody molecules
|
WO2013165940A1
(en)
|
2012-05-01 |
2013-11-07 |
Genentech, Inc. |
Anti-pmel17 antibodies and immunoconjugates
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
EP2849789A4
(en)
*
|
2012-05-14 |
2016-02-24 |
Hoffmann La Roche |
COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING TUMORS
|
US9504756B2
(en)
*
|
2012-05-15 |
2016-11-29 |
Seattle Genetics, Inc. |
Self-stabilizing linker conjugates
|
CN107982545B
(zh)
*
|
2012-05-15 |
2021-04-09 |
联宁(苏州)生物制药有限公司 |
药物偶联物,偶联方法,及其用途
|
JP6423340B2
(ja)
|
2012-05-15 |
2018-11-14 |
シアトル ジェネティクス,インコーポレイティド |
自己安定化リンカー結合体
|
US20130309223A1
(en)
|
2012-05-18 |
2013-11-21 |
Seattle Genetics, Inc. |
CD33 Antibodies And Use Of Same To Treat Cancer
|
CN104540519B
(zh)
|
2012-05-21 |
2018-06-01 |
基因泰克公司 |
抗Ly6E抗体和免疫缀合物及使用方法
|
US9522940B2
(en)
|
2012-05-23 |
2016-12-20 |
Pieris Pharmaceuticals Gmbh |
Lipocalin muteins with binding-affinity for glypican-3 (GPC-3) and use of lipocalin muteins for target-specific delivery to cells expressing GPC-3
|
EP3505534A1
(en)
|
2012-06-08 |
2019-07-03 |
Sutro Biopharma, Inc. |
Antibodies comprising sitespecific nonnatural amino acid residues, methods of their preparation and methods of their use
|
CA2875096A1
(en)
|
2012-06-15 |
2013-12-19 |
Genentech, Inc. |
Anti-pcsk9 antibodies, formulations, dosing, and methods of use
|
DK2863955T3
(en)
|
2012-06-26 |
2017-01-23 |
Sutro Biopharma Inc |
MODIFIED FC PROTEINS, INCLUDING LOCATION-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES THEREOF, METHODS OF PRODUCING ITS AND PROCEDURES FOR USE THEREOF
|
CN104395340B9
(zh)
|
2012-06-27 |
2018-11-30 |
弗·哈夫曼-拉罗切有限公司 |
包含至少两个不同靶向实体的定制选择性和多特异性治疗分子的方法及其用途
|
MX2014014804A
(es)
|
2012-06-27 |
2015-02-12 |
Hoffmann La Roche |
Metodo para la elaboracion de conjugados de la region fc de anticuerpos que comprenden por lo menos una entidad de union que se une especificamente a un objetivo y usos del mismo.
|
CA2871880A1
(en)
|
2012-06-27 |
2014-01-03 |
F. Hoffmann-La Roche Ag |
Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof
|
CN104394886B
(zh)
|
2012-07-04 |
2017-05-24 |
弗·哈夫曼-拉罗切有限公司 |
抗茶碱抗体及使用方法
|
EP3138580B1
(en)
|
2012-07-04 |
2021-03-03 |
F. Hoffmann-La Roche AG |
Covalently linked antigen-antibody conjugates
|
BR112014030844A2
(pt)
|
2012-07-04 |
2019-10-15 |
Hoffmann La Roche |
anticorpo anti-biotina humanizado, formulação farmacêutica e uso do anticorpo
|
EP3632462A1
(en)
|
2012-07-06 |
2020-04-08 |
Genmab B.V. |
Dimeric protein with triple mutations
|
EP2869845B1
(en)
|
2012-07-06 |
2019-08-28 |
Genmab B.V. |
Dimeric protein with triple mutations
|
BR112015000439A2
(pt)
|
2012-07-09 |
2017-12-19 |
Genentech Inc |
imunoconjugado , formulação farmacêutica e métodos de tratamento de um indivíduo e de inibição da proliferação
|
US20140030279A1
(en)
|
2012-07-09 |
2014-01-30 |
Spirogen Sarl |
Anti-cd22 antibodies and immunoconjugates
|
CN104411337A
(zh)
|
2012-07-09 |
2015-03-11 |
基因泰克公司 |
包含抗cd79b抗体的免疫偶联物
|
EA201590171A1
(ru)
|
2012-07-09 |
2015-09-30 |
Дженентек, Инк. |
ИММУНОКОНЪЮГАТЫ, СОДЕРЖАЩИЕ АНТИТЕЛА К CD79b
|
HUE061182T2
(hu)
|
2012-07-12 |
2023-05-28 |
Hangzhou Dac Biotech Co Ltd |
Sejtkötõ molekulák konjugátumai citotoxikus szerekkel
|
US11873281B2
(en)
*
|
2012-07-12 |
2024-01-16 |
Hangzhou Dac Biotech Co., Ltd. |
Conjugates of cell binding molecules with cytotoxic agents
|
EP2872894B1
(en)
|
2012-07-13 |
2019-04-17 |
Innate Pharma |
Screening of conjugated antibodies
|
RS57704B1
(sr)
|
2012-07-13 |
2018-12-31 |
Roche Glycart Ag |
Bispecifična anti-vegf/anti-ang-2 antitela i njihova primena u lečenju vaskularnih bolesti oka
|
CN103566377A
(zh)
|
2012-07-18 |
2014-02-12 |
上海博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
CN104717979A
(zh)
|
2012-08-02 |
2015-06-17 |
基因泰克公司 |
抗etbr抗体和免疫偶联物
|
WO2014022680A1
(en)
|
2012-08-02 |
2014-02-06 |
Genentech, Inc. |
Anti-etbr antibodies and immunoconjugates
|
JP6302909B2
(ja)
|
2012-08-18 |
2018-03-28 |
アカデミア シニカAcademia Sinica |
シアリダーゼの同定および画像化のための細胞透過性プローブ
|
MX364265B
(es)
|
2012-08-23 |
2019-04-17 |
Agensys Inc |
Conjugados de anticuerpo farmaco (adc) que enlazan a las proteinas 158p1d7.
|
SI2890402T1
(sl)
|
2012-08-31 |
2019-07-31 |
Sutro Biopharma, Inc. |
Modificirane aminokisline vsebujoče acido skupino
|
US9790268B2
(en)
|
2012-09-12 |
2017-10-17 |
Genzyme Corporation |
Fc containing polypeptides with altered glycosylation and reduced effector function
|
US9279016B2
(en)
|
2012-09-19 |
2016-03-08 |
Abbvie Biotherapeutics Inc. |
Methods for identifying antibodies with reduced immunogenicity
|
WO2014046441A1
(ko)
|
2012-09-20 |
2014-03-27 |
(주)셀트리온 |
돌라스타틴 10 유도체, 그의 제조방법 및 그를 포함하는 항암제 조성물
|
CN104704004B
(zh)
|
2012-10-08 |
2019-12-31 |
罗切格利卡特公司 |
包含两个Fab片段的无Fc的抗体及使用方法
|
CN110256469B
(zh)
|
2012-10-12 |
2022-05-17 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓及其结合物
|
PL2906298T3
(pl)
|
2012-10-12 |
2019-04-30 |
Adc Therapeutics Sa |
Koniugaty pirolobenzodiazepina - przeciwciało
|
MX364327B
(es)
|
2012-10-12 |
2019-04-23 |
Medimmune Ltd |
Conjugados del anticuerpo pirrolobenzodiazepina - anti-cd22.
|
DK2906253T3
(en)
|
2012-10-12 |
2018-10-22 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine anti-PSMA antibody conjugates
|
ES2660029T3
(es)
|
2012-10-12 |
2018-03-20 |
Medimmune Limited |
Conjugados de anticuerpo-pirrolobenzodiazepinas
|
EP2906296B1
(en)
|
2012-10-12 |
2018-03-21 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine-antibody conjugates
|
ES2680153T3
(es)
|
2012-10-12 |
2018-09-04 |
Adc Therapeutics Sa |
Conjugados de anticuerpos anti-PSMA-pirrolobenzodiazepinas
|
EP2906249B1
(en)
|
2012-10-12 |
2018-06-27 |
MedImmune Limited |
Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
|
NO2789793T3
(el)
*
|
2012-10-24 |
2018-01-27 |
|
|
BR112015008376A2
(pt)
|
2012-10-24 |
2017-09-26 |
Polytherics Ltd |
conjugados fármaco-proteína
|
US10189906B2
(en)
|
2012-11-01 |
2019-01-29 |
Max-Delrück-Centrum Für Molekulare Medizin |
Antibody that binds CD269 (BCMA) suitable for use in the treatment of plasma cell diseases such as multiple myeloma and autoimmune diseases
|
CA2890571A1
(en)
|
2012-11-07 |
2014-05-15 |
Kenneth G. Geles |
Anti-notch3 antibodies and antibody-drug conjugates
|
EP2917243B1
(en)
|
2012-11-08 |
2018-03-14 |
F.Hoffmann-La Roche Ag |
Her3 antigen binding proteins binding to the beta-hairpin of her3
|
EP3564259A3
(en)
|
2012-11-09 |
2020-02-12 |
Innate Pharma |
Recognition tags for tgase-mediated conjugation
|
EP3461501A1
(en)
|
2012-11-13 |
2019-04-03 |
F. Hoffmann-La Roche AG |
Anti-hemagglutinin antibodies and methods of use
|
EP2922818B1
(en)
|
2012-11-24 |
2018-09-05 |
Hangzhou Dac Biotech Co., Ltd |
Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
|
US20140154255A1
(en)
|
2012-11-30 |
2014-06-05 |
Abbvie Biotherapeutics Inc. |
Anti-vegf antibodies and their uses
|
US9353150B2
(en)
|
2012-12-04 |
2016-05-31 |
Massachusetts Institute Of Technology |
Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment
|
EP2928504B1
(en)
|
2012-12-10 |
2019-02-20 |
Mersana Therapeutics, Inc. |
Protein-polymer-drug conjugates
|
EP2928503B1
(en)
|
2012-12-10 |
2019-02-20 |
Mersana Therapeutics, Inc. |
Conjugates of auristatin compounds
|
US9872918B2
(en)
|
2012-12-12 |
2018-01-23 |
Mersana Therapeutics, Inc. |
Hydroxyl-polymer-drug-protein conjugates
|
CA2896690A1
(en)
|
2012-12-21 |
2014-06-26 |
Abgenomics International Inc. |
Hydrophilic self-immolative linkers and conjugates thereof
|
JP6449777B2
(ja)
|
2012-12-21 |
2019-01-09 |
シアトル ジェネティックス, インコーポレイテッド |
抗ntb−a抗体ならびに関連する組成物および方法
|
US9814784B2
(en)
|
2013-01-03 |
2017-11-14 |
Celltrion, Inc. |
Antibody-linker-drug conjugate, preparation method therefor, and anticancer drug composition containing same
|
WO2014107739A1
(en)
|
2013-01-07 |
2014-07-10 |
Eleven Biotherapeutics, Inc. |
Antibodies against pcsk9
|
EA201500741A1
(ru)
|
2013-01-10 |
2016-01-29 |
Генмаб Б.В. |
ВАРИАНТЫ Fc-ОБЛАСТИ IGG1 ЧЕЛОВЕКА И ИХ ПРИМЕНЕНИЕ
|
SI2943511T1
(sl)
|
2013-01-14 |
2020-01-31 |
Xencor, Inc. |
Novi heterodimerni proteini
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
WO2014113510A1
(en)
|
2013-01-15 |
2014-07-24 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
RU2519546C1
(ru)
|
2013-01-16 |
2014-06-10 |
Общество С Ограниченной Ответственностью "Биоинтегратор" (Ооо "Биоинтегратор") |
КОНЪЮГАТЫ И МАЛЫЕ МОЛЕКУЛЫ, ВЗАИМОДЕЙСТВУЮЩИЕ С РЕЦЕПТОРОМ CD16а
|
CN103933575B
(zh)
*
|
2013-01-23 |
2017-09-29 |
上海新理念生物医药科技有限公司 |
一种三齿型连接子及其应用
|
US10029017B2
(en)
|
2013-01-29 |
2018-07-24 |
The Regents Of The University Of California |
Pretargeted activatable cell penetrating peptide with intracellularly releasable prodrug
|
MX366375B
(es)
|
2013-01-30 |
2019-07-05 |
Avelas Biosciences Inc |
Moleculas de administracion selectiva y metodos de uso.
|
PT2958944T
(pt)
|
2013-02-22 |
2019-06-27 |
Medimmune Ltd |
Conjugados de anticorpos anti-dll3 e pbd e suas utilizações
|
MX2015010791A
(es)
|
2013-02-22 |
2015-11-26 |
Hoffmann La Roche |
Metodos para tratar el cancer y prevenir la resistencia a farmacos.
|
CA2896259A1
(en)
|
2013-02-26 |
2014-09-04 |
Roche Glycart Ag |
Anti-mcsp antibodies
|
JP2016510751A
(ja)
|
2013-03-06 |
2016-04-11 |
ジェネンテック, インコーポレイテッド |
抗がん剤耐性を治療及び予防する方法
|
SG11201506088RA
(en)
|
2013-03-11 |
2015-09-29 |
Genzyme Corp |
Hyperglycosylated binding polypeptides
|
EP3299391B1
(en)
|
2013-03-14 |
2019-12-04 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
RU2015139054A
(ru)
|
2013-03-14 |
2017-04-19 |
Дженентек, Инк. |
Способы лечения рака и профилактики лекарственной резистентности рака
|
KR20150128707A
(ko)
|
2013-03-15 |
2015-11-18 |
제넨테크, 인크. |
간암의 진단 및 치료를 위한 조성물 및 방법
|
EP4137160A1
(en)
|
2013-03-15 |
2023-02-22 |
AbbVie Inc. |
Antibody drug conjugate (adc) purification
|
MX2015012872A
(es)
|
2013-03-15 |
2016-02-03 |
Ac Immune Sa |
Anticuerpos anti-tau y metodos de uso.
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
EP2968582B1
(en)
|
2013-03-15 |
2020-07-01 |
Innate Pharma |
Solid phase tgase-mediated conjugation of antibodies
|
US20150010539A1
(en)
|
2013-03-15 |
2015-01-08 |
Abbvie Biotherapeutics Inc. |
Anti-cd25 antibodies and their uses
|
CA2904527A1
(en)
|
2013-03-15 |
2014-09-18 |
Abbvie Biotechnology Ltd. |
Anti-cd25 antibodies and their uses
|
KR20150130451A
(ko)
|
2013-03-15 |
2015-11-23 |
제넨테크, 인크. |
암 치료 방법 및 항암제 내성 예방을 위한 방법
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
DK2970486T3
(en)
|
2013-03-15 |
2018-08-06 |
Xencor Inc |
MODULATION OF T-CELLS WITH BISPECIFIC ANTIBODIES AND FC-FUSIONS
|
KR20150131177A
(ko)
|
2013-03-15 |
2015-11-24 |
제넨테크, 인크. |
항-CRTh2 항체 및 그의 용도
|
JP6449229B2
(ja)
|
2013-03-15 |
2019-01-09 |
アッヴィ・バイオセラピューティクス・インコーポレイテッド |
Fc変異体
|
TW201945032A
(zh)
|
2013-03-15 |
2019-12-01 |
德商艾伯維德國有限及兩合公司 |
抗-egfr抗體藥物結合物調配物
|
KR102211176B1
(ko)
|
2013-03-15 |
2021-02-01 |
젠코어 인코포레이티드 |
이형이량체 단백질
|
CN118547067A
(zh)
|
2013-03-15 |
2024-08-27 |
豪夫迈·罗氏有限公司 |
治疗pd-1和pd-l1相关疾患的生物标志物和方法
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
EP2976362B1
(en)
|
2013-03-19 |
2019-10-23 |
Beijing Shenogen Pharma Group Ltd. |
Antibodies and methods for treating estrogen receptor-associated diseases
|
AR095882A1
(es)
|
2013-04-22 |
2015-11-18 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9
|
WO2014177459A2
(en)
|
2013-04-29 |
2014-11-06 |
F. Hoffmann-La Roche Ag |
Fc-receptor binding modified asymmetric antibodies and methods of use
|
CA2910945A1
(en)
|
2013-05-08 |
2014-11-13 |
Zymeworks Inc. |
Bispecific her2 and her3 antigen binding constructs
|
US9708406B2
(en)
|
2013-05-20 |
2017-07-18 |
Genentech, Inc. |
Anti-transferrin receptor antibodies and methods of use
|
BR112015029838A2
(pt)
*
|
2013-05-31 |
2017-09-26 |
Genentech Inc |
anticorpos, composições, ácido nucleico isolado, vetor, célula hospedeira isolada, método de produção de anticorpos, composto, conjugado de anticorpo e antibiótico, processo de elaboração do composto, intermediário entre ligante e antibiótico, método de tratamento de infecções bacterianas e método de matar staphylococcus aureus
|
RU2687044C2
(ru)
|
2013-05-31 |
2019-05-06 |
Дженентек, Инк. |
Антитела против стеночной тейхоевой кислоты и их конъюгаты
|
US9803002B2
(en)
|
2013-05-31 |
2017-10-31 |
Genentench, Inc. |
Anti-wall teichoic antibodies and conjugates
|
US20140356375A1
(en)
*
|
2013-05-31 |
2014-12-04 |
Genentech, Inc. |
Anti-wall teichoic antibodies and conjugates
|
CN105658240A
(zh)
|
2013-06-04 |
2016-06-08 |
西托姆克斯治疗公司 |
用于缀合可活化抗体的组合物和方法
|
NZ714765A
(en)
*
|
2013-06-06 |
2021-12-24 |
Pf Medicament |
Anti-c10orf54 antibodies and uses thereof
|
WO2014197866A1
(en)
|
2013-06-06 |
2014-12-11 |
Igenica Biotherapeutics, Inc. |
Modified antibodies and related compounds, compositions, and methods of use
|
US11229711B2
(en)
*
|
2013-06-06 |
2022-01-25 |
Magenta Therapeutics, Inc. |
Linkers for antibody-drug conjugates and related compounds, compositions, and methods of use
|
WO2014202773A1
(en)
|
2013-06-20 |
2014-12-24 |
Innate Pharma |
Enzymatic conjugation of polypeptides
|
EP3010548A1
(en)
|
2013-06-21 |
2016-04-27 |
Innate Pharma |
Enzymatic conjugation of polypeptides
|
TWI725931B
(zh)
|
2013-06-24 |
2021-05-01 |
美商建南德克公司 |
抗fcrh5抗體
|
EP3013365B1
(en)
|
2013-06-26 |
2019-06-05 |
Academia Sinica |
Rm2 antigens and use thereof
|
US9981030B2
(en)
|
2013-06-27 |
2018-05-29 |
Academia Sinica |
Glycan conjugates and use thereof
|
EP3019522B1
(en)
|
2013-07-10 |
2017-12-13 |
Sutro Biopharma, Inc. |
Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
US10208125B2
(en)
|
2013-07-15 |
2019-02-19 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Anti-mucin 1 binding agents and uses thereof
|
AU2014290361B2
(en)
|
2013-07-18 |
2019-04-18 |
Taurus Biosciences, Llc |
Humanized antibodies with ultralong complementarity determining regions
|
US20160168231A1
(en)
|
2013-07-18 |
2016-06-16 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
UA118198C2
(uk)
|
2013-08-01 |
2018-12-10 |
Ейдженсіс, Інк. |
Кон'югат антитіло-лікарський засіб, який зв'язується з білком cd37
|
JP6993084B2
(ja)
|
2013-08-12 |
2022-02-03 |
ジェネンテック, インコーポレイテッド |
1-(クロロメチル)-2,3-ジヒドロ-1h-ベンゾ[e]インドール二量体抗体 - 薬物コンジュゲート化合物、並びに使用及び処置の方法
|
EP3041507B1
(en)
|
2013-08-26 |
2021-06-30 |
BioNTech Research and Development, Inc. |
Nucleic acids encoding human antibodies to sialyl-lewis a
|
AU2014312310A1
(en)
|
2013-08-28 |
2016-04-07 |
Abbvie Stemcentrx Llc |
Novel SEZ6 modulators and methods of use
|
SG11201601424PA
(en)
|
2013-08-28 |
2016-03-30 |
Stemcentrx Inc |
Site-specific antibody conjugation methods and compositions
|
WO2015035044A2
(en)
|
2013-09-04 |
2015-03-12 |
Abbvie Biotherapeutics Inc. |
Fc VARIANTS WITH IMPROVED ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY
|
AU2014317889B2
(en)
|
2013-09-06 |
2020-03-05 |
Academia Sinica |
Human iNKT cell activation using glycolipids with altered glycosyl groups
|
AR097584A1
(es)
|
2013-09-12 |
2016-03-23 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano
|
EP3044236A2
(en)
|
2013-09-12 |
2016-07-20 |
Halozyme, Inc. |
Modified anti-epidermal growth factor receptor antibodies and methods of use thereof
|
CN105518027A
(zh)
|
2013-09-17 |
2016-04-20 |
豪夫迈·罗氏有限公司 |
使用抗lgr5抗体的方法
|
WO2015052534A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
BR112016007736B1
(pt)
|
2013-10-11 |
2022-09-27 |
Mersana Therapeutics, Inc |
Armação polimérica, e, composição farmacêutica
|
EP3054983B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
EP3055298B1
(en)
|
2013-10-11 |
2020-04-29 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
WO2015052535A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
EP3620470B1
(en)
|
2013-10-11 |
2023-07-26 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Tem8 antibodies and their use
|
KR102357173B1
(ko)
|
2013-10-11 |
2022-01-27 |
옥스포드 바이오테라퓨틱스 리미티드 |
암을 치료하기 위한 ly75에 대한 접합 항체
|
KR102572149B1
(ko)
|
2013-10-11 |
2023-08-30 |
아사나 바이오사이언시스 엘엘씨 |
단백질-폴리머-약물 접합체
|
PL3057585T3
(pl)
|
2013-10-15 |
2020-12-28 |
Seagen Inc. |
Pegylowane elementy lek-łącznik do poprawy farmakokinetyki koniugatu ligand-lek
|
AU2014337317A1
(en)
|
2013-10-15 |
2016-09-15 |
Sorrento Therapeutics Inc. |
Drug-conjugates with a targeting molecule and two different drugs
|
MX2016004802A
(es)
|
2013-10-18 |
2016-07-18 |
Genentech Inc |
Anticuerpos anti-r-espondina (anti-rspo) y metodos de uso.
|
WO2015057461A2
(en)
|
2013-10-18 |
2015-04-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibodies that specifically bind ataxia telangiectasia-mutated and rad3-related kinase phosphorylated at position 1989 and their use
|
KR20160068963A
(ko)
|
2013-10-21 |
2016-06-15 |
제넨테크, 인크. |
항-Ly6E 항체 및 사용 방법
|
US20160280798A1
(en)
|
2013-11-06 |
2016-09-29 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Service |
Alk antibodies, conjugates, and chimeric antigen receptors, and their use
|
AU2014353150A1
(en)
|
2013-11-19 |
2016-07-07 |
Vanderbilt University |
Substituted imidazopyridine and triazolopyridine compounds as negative allosteric modulators of mGluR5
|
EP3071237B1
(en)
|
2013-11-21 |
2024-06-26 |
Genmab A/S |
Antibody-drug conjugate lyophilised formulation
|
EP3074036B1
(en)
|
2013-11-25 |
2019-09-18 |
Seattle Genetics, Inc. |
Preparing antibodies from cho cell cultures for conjugation
|
AU2014357292B2
(en)
|
2013-11-27 |
2020-06-25 |
Zymeworks Bc Inc. |
Bispecific antigen-binding constructs targeting HER2
|
CN103665104B
(zh)
*
|
2013-12-09 |
2015-05-20 |
天津市康信医药科技有限公司 |
一种mmaf中间体五肽的合成方法
|
AR098743A1
(es)
|
2013-12-13 |
2016-06-08 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-cd33
|
CA2929565A1
(en)
|
2013-12-16 |
2015-06-25 |
Genentech, Inc. |
1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
|
MX371092B
(es)
|
2013-12-16 |
2020-01-16 |
Genentech Inc |
Compuestos peptidomimeticos y conjugados de anticuerpo-farmaco de los mismos.
|
SG11201604877UA
(en)
|
2013-12-17 |
2016-07-28 |
Novartis Ag |
Cytotoxic peptides and conjugates thereof
|
EP3083689B1
(en)
|
2013-12-17 |
2020-05-27 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
TWI777502B
(zh)
|
2013-12-19 |
2022-09-11 |
美商西雅圖遺傳學公司 |
與標的-藥物結合物併用之亞甲基胺基甲酸酯連接物
|
EP3086814B1
(de)
|
2013-12-23 |
2020-06-24 |
Bayer Pharma Aktiengesellschaft |
Binder-konjugate (adcs) mit ksp-inhibitoren
|
TWI670283B
(zh)
|
2013-12-23 |
2019-09-01 |
美商建南德克公司 |
抗體及使用方法
|
BR112016015105A8
(pt)
|
2013-12-27 |
2018-04-24 |
Var2 Pharmaceuticals Aps |
conjugados var2csa-droga
|
KR102384740B1
(ko)
|
2013-12-27 |
2022-04-07 |
자임워크스 인코포레이티드 |
약물 접합체를 위한 설폰아마이드-함유 연결 시스템
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
JP6521464B2
(ja)
|
2014-01-03 |
2019-05-29 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
共有結合で連結されたポリペプチド毒素−抗体コンジュゲート
|
EP3089996B1
(en)
|
2014-01-03 |
2021-07-28 |
F. Hoffmann-La Roche AG |
Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles
|
BR112016012666A2
(pt)
|
2014-01-03 |
2017-09-26 |
Hoffmann La Roche |
conjugado, anticorpos, formulação farmacêutica e usos de conjugado
|
CN104861067A
(zh)
*
|
2014-01-10 |
2015-08-26 |
博笛生物科技有限公司 |
用于免疫疗法的化合物和组合物
|
WO2015103989A1
(en)
|
2014-01-10 |
2015-07-16 |
Shanghai Birdie Biotech, Inc. |
Compounds and compositions for immunotherapy
|
CN104861064A
(zh)
*
|
2014-01-10 |
2015-08-26 |
博笛生物科技有限公司 |
靶向表达egfr的肿瘤的化合物和组合物
|
CN104861063A
(zh)
*
|
2014-01-10 |
2015-08-26 |
博笛生物科技有限公司 |
靶向her2阳性肿瘤的化合物和组合物
|
CA2931005A1
(en)
|
2014-01-15 |
2015-07-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Cartilage targeting agents and their use
|
WO2015109180A2
(en)
|
2014-01-16 |
2015-07-23 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
CN106413756A
(zh)
|
2014-01-24 |
2017-02-15 |
豪夫迈·罗氏有限公司 |
使用抗steap1抗体和免疫缀合物的方法
|
CN105636591B
(zh)
*
|
2014-01-29 |
2020-04-07 |
上海恒瑞医药有限公司 |
配体-细胞毒性药物偶联物、其制备方法及其应用
|
MX2016010295A
(es)
|
2014-02-11 |
2016-10-17 |
Seattle Genetics Inc |
Reduccion selectiva de proteinas.
|
AU2015217271B2
(en)
|
2014-02-12 |
2018-10-25 |
Genentech, Inc. |
Anti-Jagged1 antibodies and methods of use
|
SG11201605886RA
(en)
*
|
2014-02-17 |
2016-09-29 |
Seattle Genetics Inc |
Hydrophilic antibody-drug conjugates
|
CR20160437A
(es)
|
2014-02-21 |
2017-02-20 |
Abbvie Stemcentrx Llc |
Conjugados de anticuerpos anti-drosophila similar a delta 3 (anti-dll3) y medicamentos para uso en el tratamiento contra melanoma
|
WO2015127405A2
(en)
|
2014-02-21 |
2015-08-27 |
Genentech, Inc. |
Anti-il-13/il-17 bispecific antibodies and uses thereof
|
CN114262344A
(zh)
|
2014-02-28 |
2022-04-01 |
杭州多禧生物科技有限公司 |
带电荷链接体及其在共轭反应上的应用
|
JP6644717B2
(ja)
|
2014-03-14 |
2020-02-12 |
ジェネンテック, インコーポレイテッド |
異種ポリペプチドを分泌させるための方法及び組成物
|
CN116333148A
(zh)
|
2014-03-19 |
2023-06-27 |
建新公司 |
靶向模块的位点特异性糖工程化
|
AU2015231210B2
(en)
|
2014-03-20 |
2019-09-12 |
Bristol-Myers Squibb Company |
Stabilized fibronectin based scaffold molecules
|
US9533982B2
(en)
|
2014-03-20 |
2017-01-03 |
Vanderbilt University |
Substituted bicyclic heteroaryl carboxamide analogs as mGluR5 negative allosteric modulators
|
PE20161211A1
(es)
|
2014-03-21 |
2016-11-27 |
Abbvie Inc |
Anticuerpos y conjugados de anticuerpo y farmaco anti-egfr
|
MA39776A
(fr)
|
2014-03-24 |
2017-02-01 |
Hoffmann La Roche |
Traitement du cancer avec des antagonistes de c-met et corrélation de ces derniers avec l'expression de hgf
|
WO2015148915A1
(en)
|
2014-03-27 |
2015-10-01 |
Academia Sinica |
Reactive labelling compounds and uses thereof
|
SG10202008629XA
(en)
|
2014-03-28 |
2020-10-29 |
Xencor Inc |
Bispecific antibodies that bind to cd38 and cd3
|
CR20160500A
(es)
|
2014-03-31 |
2016-12-14 |
Genentech Inc |
Anticuerpos anti-ox40 y métodos de uso
|
BR112016022345A2
(pt)
|
2014-03-31 |
2017-10-10 |
Genentech Inc |
terapia de combinação compreendendo agentes antiangiogênese e agonistas de ligação de ox40
|
US9260478B2
(en)
|
2014-04-04 |
2016-02-16 |
Shanghui Hu |
Potent and efficient cytotoxic peptides and antibody-drug conjugates thereof and their synthesis
|
MX2016012258A
(es)
*
|
2014-04-08 |
2017-01-06 |
Seattle Genetics Inc |
Dosificacion optima de un conjugado del farmaco del anticuerpo-cd19.
|
ES2736505T3
(es)
|
2014-04-29 |
2020-01-02 |
For All Designated States |
Nuevo conjugado estable de anticuerpo-fármaco, método de preparación y uso del mismo
|
KR102603417B1
(ko)
|
2014-05-06 |
2023-11-20 |
제넨테크, 인크. |
포유동물 세포를 사용한 이종다량체 단백질의 생산
|
MX2016015162A
(es)
|
2014-05-22 |
2017-03-03 |
Genentech Inc |
Anticuerpos anti - gpc3 e inmunoconjugados.
|
RU2016144405A
(ru)
|
2014-05-23 |
2018-06-26 |
Дженентек, Инк. |
MiT БИОМАРКЕРЫ И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
EP3149037A4
(en)
|
2014-05-27 |
2018-01-10 |
Academia Sinica |
Anti-her2 glycoantibodies and uses thereof
|
CA2950415A1
(en)
|
2014-05-27 |
2015-12-03 |
Academia Sinica |
Anti-cd20 glycoantibodies and uses thereof
|
JP6894239B2
(ja)
|
2014-05-27 |
2021-06-30 |
アカデミア シニカAcademia Sinica |
増強された抗体の有効性のための普遍的グリコフォームに関する組成物および方法
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
EP3154582A4
(en)
|
2014-05-28 |
2018-01-10 |
Academia Sinica |
Anti-tnf-alpha glycoantibodies and uses thereof
|
KR101628872B1
(ko)
|
2014-05-28 |
2016-06-09 |
주식회사 레고켐 바이오사이언스 |
자가-희생 기를 포함하는 화합물
|
CA3121083C
(en)
|
2014-06-04 |
2023-08-15 |
Biontech Research And Development, Inc. |
Human monoclonal antibodies to ganglioside gd2
|
JP6663863B2
(ja)
|
2014-06-12 |
2020-03-13 |
シーダーズ−サイナイ メディカル センター |
がん治療のための組成物及び方法
|
CN113332449B
(zh)
|
2014-06-12 |
2023-12-22 |
石药集团巨石生物制药有限公司 |
酶法制备同质的抗体-药物缀合物
|
EA201692530A1
(ru)
|
2014-06-13 |
2017-07-31 |
Новартис Аг |
Цитотоксические пептиды и их конъюгаты
|
CN107073121A
(zh)
|
2014-06-13 |
2017-08-18 |
基因泰克公司 |
治疗及预防癌症药物抗性的方法
|
TWI695011B
(zh)
|
2014-06-18 |
2020-06-01 |
美商梅爾莎納醫療公司 |
抗her2表位之單株抗體及其使用之方法
|
JP2017525755A
(ja)
*
|
2014-06-20 |
2017-09-07 |
アブジェノミクス インターナショナル インコーポレイテッド.Abgenomics International Inc. |
Her2抗体−薬物抱合体
|
EP3157960A4
(en)
|
2014-06-20 |
2018-01-24 |
BioAlliance C.V. |
Anti-folate receptor aplha (fra) antibody-drug conjugates and methods of using thereof
|
CA2947504A1
(en)
|
2014-06-26 |
2015-12-30 |
F. Hoffmann-La Roche Ag |
Anti-brdu antibodies and methods of use
|
EP3160513B1
(en)
|
2014-06-30 |
2020-02-12 |
Glykos Finland Oy |
Saccharide derivative of a toxic payload and antibody conjugates thereof
|
JP6760919B2
(ja)
|
2014-07-09 |
2020-09-23 |
バーディー バイオファーマシューティカルズ インコーポレイテッド |
腫瘍を治療するための抗pd−l1組み合わせ
|
IL296633A
(en)
|
2014-07-11 |
2022-11-01 |
Genmab As |
Antibodies that bind axl
|
BR112017000130A2
(pt)
|
2014-07-11 |
2018-01-09 |
Genentech Inc |
método para atenuar a toxicidade associada à inibição da via de notch e método de tratamento do câncer
|
WO2016008112A1
(en)
*
|
2014-07-16 |
2016-01-21 |
Medshine Discovery Inc. |
Linkers and application towards adc thereof
|
WO2016014984A1
(en)
|
2014-07-24 |
2016-01-28 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
ES2848857T3
(es)
|
2014-07-31 |
2021-08-12 |
Us Gov Health & Human Services |
Anticuerpos monoclonales humanos contra EphA4 y su uso
|
KR20230172625A
(ko)
|
2014-08-28 |
2023-12-22 |
바이오아트라, 인코퍼레이티드 |
변형된 t 세포에 대한 조건부 활성 키메라 항원 수용체
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
CN112587672A
(zh)
|
2014-09-01 |
2021-04-02 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
WO2016040369A2
(en)
|
2014-09-08 |
2016-03-17 |
Academia Sinica |
HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS
|
SG10202006504QA
(en)
|
2014-09-11 |
2020-08-28 |
Seattle Genetics Inc |
Targeted delivery of tertiary amine-containing drug substances
|
CN113698488A
(zh)
|
2014-09-12 |
2021-11-26 |
基因泰克公司 |
抗-b7-h4抗体及免疫缀合物
|
US10077318B2
(en)
|
2014-09-12 |
2018-09-18 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
AR101846A1
(es)
|
2014-09-12 |
2017-01-18 |
Genentech Inc |
Anticuerpos anti-cll-1 e inmunoconjugados
|
ES2830385T3
(es)
|
2014-09-12 |
2021-06-03 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-HER2
|
JP6730261B2
(ja)
|
2014-09-17 |
2020-07-29 |
ジェネンテック, インコーポレイテッド |
抗her2抗体を含む免疫複合体
|
HUE057768T2
(hu)
|
2014-09-17 |
2022-06-28 |
Zymeworks Inc |
Citotoxikus és antimitotikus vegyületek és azok alkalmazásának módszerei
|
RS60349B8
(sr)
|
2014-09-23 |
2022-10-31 |
Hoffmann La Roche |
Postupak upotrebe anti-cd79b imunokonjugata
|
US10385380B2
(en)
|
2014-10-02 |
2019-08-20 |
The Regents Of The University Of California |
Personalized protease assay to measure protease activity in neoplasms
|
US9550778B2
(en)
|
2014-10-03 |
2017-01-24 |
Vanderbilt University |
Substituted 6-aryl-imidazopyridine and 6-aryl-triazolopyridine carboxamide analogs as negative allosteric modulators of mGluR5
|
US10064952B2
(en)
|
2014-10-09 |
2018-09-04 |
Genzyme Corporation |
Glycoengineered antibody drug conjugates
|
EP3204005A1
(en)
*
|
2014-10-10 |
2017-08-16 |
Pfizer Inc |
Synergistic auristatin combinations
|
JP2017536102A
(ja)
|
2014-10-16 |
2017-12-07 |
ジェネンテック, インコーポレイテッド |
抗アルファ−シヌクレイン抗体及び使用方法
|
GB201418809D0
(en)
|
2014-10-22 |
2014-12-03 |
Univ Swansea |
Therapeutic agents and uses thereof
|
EP3220956B1
(en)
*
|
2014-10-24 |
2023-08-09 |
Abzena (UK) Limited |
Conjugates and conjugating reagents
|
GB201419108D0
(en)
*
|
2014-10-27 |
2014-12-10 |
Glythera Ltd |
Materials and methods relating to linkers for use in antibody drug conjugates
|
JP2017537891A
(ja)
|
2014-10-31 |
2017-12-21 |
ジェネンテック, インコーポレイテッド |
抗il−17a及びil−17f交差反応性抗体変異体、ならびにそれらを含む組成物、それらを作製する方法、及び使用する方法
|
US20160161485A1
(en)
|
2014-11-03 |
2016-06-09 |
Genentech, Inc. |
Assays for detecting t cell immune subsets and methods of use thereof
|
CN114381521A
(zh)
|
2014-11-03 |
2022-04-22 |
豪夫迈·罗氏有限公司 |
用于ox40激动剂治疗的功效预测和评估的方法和生物标志物
|
WO2016073157A1
(en)
|
2014-11-06 |
2016-05-12 |
Genentech, Inc. |
Anti-ang2 antibodies and methods of use thereof
|
MX2017005148A
(es)
|
2014-11-06 |
2017-08-08 |
Hoffmann La Roche |
Variantes de region fc con union del receptor fc neonatal (fcrn) modificado y metodos de uso.
|
US10093730B2
(en)
|
2014-11-10 |
2018-10-09 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
WO2016081640A1
(en)
|
2014-11-19 |
2016-05-26 |
Genentech, Inc. |
Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use
|
BR112017010498A2
(pt)
|
2014-11-19 |
2017-12-26 |
Axon Neuroscience Se |
anticorpos tau humanizados em doença de alzheimer
|
US10882920B2
(en)
|
2014-11-19 |
2021-01-05 |
Genentech, Inc. |
Antibodies against BACE1 and use thereof for neural disease immunotherapy
|
EP3221362B1
(en)
|
2014-11-19 |
2019-07-24 |
F.Hoffmann-La Roche Ag |
Anti-transferrin receptor antibodies and methods of use
|
JP6805142B2
(ja)
|
2014-11-21 |
2020-12-23 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
Cd73に対する抗体およびその使用
|
WO2016081746A2
(en)
|
2014-11-21 |
2016-05-26 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
EP3702367B1
(en)
|
2014-11-25 |
2024-05-15 |
Bristol-Myers Squibb Company |
Novel pd-l1 binding polypeptides for imaging
|
CA2968447A1
(en)
|
2014-11-25 |
2016-06-02 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates and their use to treat neoplasms
|
AU2015353416C1
(en)
|
2014-11-26 |
2022-01-27 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and CD38
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
NZ732144A
(en)
|
2014-11-26 |
2020-04-24 |
Xencor Inc |
Heterodimeric antibodies that bind cd3 and tumor antigens
|
CA2968258A1
(en)
|
2014-11-27 |
2016-06-02 |
Zymeworks Inc. |
Methods of using bispecific antigen-binding constructs targeting her2
|
EP3227332B1
(en)
|
2014-12-03 |
2019-11-06 |
F.Hoffmann-La Roche Ag |
Multispecific antibodies
|
RU2731055C2
(ru)
*
|
2014-12-03 |
2020-08-28 |
Дженентек, Инк. |
Конъюгаты антитела к staphylococcus aureus с рифамицином и их применение
|
MX2017007231A
(es)
|
2014-12-03 |
2017-11-08 |
Genentech Inc |
Conjugados de rifamicina y anticuerpos contra el staphylococcuss aureus y usos de estos.
|
SG10202008302XA
(en)
|
2014-12-04 |
2020-10-29 |
Celgene Corp |
Biomolecule conjugates
|
LT3227336T
(lt)
|
2014-12-05 |
2019-09-25 |
F. Hoffmann-La Roche Ag |
Anti-cd79b antikūnai ir jų naudojimo būdai
|
WO2016094517A1
(en)
*
|
2014-12-09 |
2016-06-16 |
Abbvie Inc. |
Bcl-xl inhibitory compounds and antibody drug conjugates including the same
|
EP3735990A1
(en)
*
|
2014-12-09 |
2020-11-11 |
Abbvie Inc. |
Antibody drug conjugates with cell permeable bcl-xl inhibitors
|
US10398774B2
(en)
|
2014-12-09 |
2019-09-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Human monoclonal antibodies against AXL
|
KR20170093943A
(ko)
*
|
2014-12-09 |
2017-08-16 |
애브비 인코포레이티드 |
낮은 세포 투과성을 갖는 bcl xl 억제 화합물 및 이를 포함하는 항체 약물 접합체
|
RU2017120039A
(ru)
|
2014-12-10 |
2019-01-10 |
Дженентек, Инк. |
Антитела к рецепторам гематоэнцефалического барьера и способы их применения
|
JP6743015B2
(ja)
|
2014-12-15 |
2020-08-19 |
バイエル ファーマ アクチエンゲゼルシャフト |
Ksp阻害剤の脱グリコシル化抗tweakr抗体との抗体薬物複合体(adc類)
|
AR103162A1
(es)
|
2014-12-19 |
2017-04-19 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos anti-c5 y métodos para su uso
|
CN107108726A
(zh)
|
2014-12-19 |
2017-08-29 |
中外制药株式会社 |
抗‑肌肉生长抑制因子抗体、包含变体fc区的多肽及使用方法
|
EP3237449A2
(en)
|
2014-12-22 |
2017-11-01 |
Xencor, Inc. |
Trispecific antibodies
|
KR20170128234A
(ko)
|
2015-01-16 |
2017-11-22 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Ror1에 특이적인 항체 및 키메라 항원 수용체
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
JP2018511557A
(ja)
|
2015-01-22 |
2018-04-26 |
中外製薬株式会社 |
2種以上の抗c5抗体の組み合わせおよび使用方法
|
EP3248005B1
(en)
|
2015-01-24 |
2020-12-09 |
Academia Sinica |
Novel glycan conjugates and methods of use thereof
|
US10590165B2
(en)
|
2015-01-28 |
2020-03-17 |
Sorrento Therapeutics, Inc. |
Antibody drug conjugates
|
SG11201706014PA
(en)
|
2015-02-05 |
2017-08-30 |
Chugai Pharmaceutical Co Ltd |
Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof
|
MX2017010102A
(es)
*
|
2015-02-15 |
2017-11-23 |
Jiangsu Hengrui Medicine Co |
Conjugado farmaco citotoxico-ligando, metodo de preparacion del mismo, y sus aplicaciones.
|
EP3261665A1
(en)
|
2015-02-24 |
2018-01-03 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Middle east respiratory syndrome coronavirus immunogens, antibodies, and their use
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
US10472395B2
(en)
|
2015-03-05 |
2019-11-12 |
Sirenas Llc |
Cyclic peptide analogs and conjugates thereof
|
AR103896A1
(es)
|
2015-03-09 |
2017-06-14 |
Agensys Inc |
Conjugados de fármacos de anticuerpos (adc) anti-proteínas flt3
|
US10676773B2
(en)
|
2015-03-10 |
2020-06-09 |
Bristol-Myers Squibb Company |
Antibodies conjugatable by transglutaminase and conjugates made therefrom
|
MX2017011432A
(es)
|
2015-03-18 |
2017-11-10 |
Seattle Genetics Inc |
Anticuerpos contra cumulo de diferenciacion 48 (cd48) y sus conjugados.
|
RU2739163C2
(ru)
|
2015-03-23 |
2020-12-21 |
Байер Фарма Акциенгезельшафт |
Анти-сеасам6 антитела и их применения
|
GB201505585D0
(en)
*
|
2015-03-31 |
2015-05-13 |
Immatics Biotechnologies Gmbh |
Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers
|
AU2016246737B2
(en)
|
2015-04-07 |
2019-11-21 |
Cornell University |
Nanoparticle immunoconjugates
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
CN106188293A
(zh)
*
|
2015-04-17 |
2016-12-07 |
江苏恒瑞医药股份有限公司 |
抗c-Met抗体和抗c-Met抗体-细胞毒性药物偶联物及其医药用途
|
WO2016165580A1
(zh)
*
|
2015-04-17 |
2016-10-20 |
江苏恒瑞医药股份有限公司 |
抗c-Met抗体和抗c-Met抗体-细胞毒性药物偶联物及其医药用途
|
CA2980189A1
(en)
|
2015-04-24 |
2016-10-27 |
Genentech, Inc. |
Multispecific antigen-binding proteins
|
JP7044553B2
(ja)
|
2015-04-24 |
2022-03-30 |
ジェネンテック, インコーポレイテッド |
結合ポリペプチドを含む細菌を特定する方法
|
CN107709363A
(zh)
|
2015-05-01 |
2018-02-16 |
基因泰克公司 |
掩蔽抗cd3抗体和使用方法
|
EP4238994A3
(en)
|
2015-05-11 |
2024-02-07 |
F. Hoffmann-La Roche AG |
Compositions and methods of treating lupus nephritis
|
CN107667119A
(zh)
|
2015-05-12 |
2018-02-06 |
豪夫迈·罗氏有限公司 |
用于癌症的治疗和诊断方法
|
CN104910277B
(zh)
*
|
2015-05-19 |
2016-02-24 |
北京东方百泰生物科技有限公司 |
新型人源化抗cd22抗体-单甲基阿里他汀e偶联物及其制备方法
|
US10596259B2
(en)
|
2015-05-20 |
2020-03-24 |
The Regents Of The University Of California |
Tumor radiosensitization with monomethyl auristatin E (MMAE) and derivatives thereof
|
KR20180010264A
(ko)
|
2015-05-29 |
2018-01-30 |
브리스톨-마이어스 스큅 컴퍼니 |
Ox40에 대한 항체 및 그의 용도
|
EP3708681A1
(en)
|
2015-05-29 |
2020-09-16 |
F. Hoffmann-La Roche AG |
Therapeutic and diagnostic methods for cancer
|
CN106267225B
(zh)
*
|
2015-05-29 |
2020-03-06 |
上海新理念生物医药科技有限公司 |
三马来酰亚胺型连接子及其应用
|
CN106279352B
(zh)
|
2015-05-29 |
2020-05-22 |
上海新理念生物医药科技有限公司 |
海兔毒素10的衍生物及其应用
|
CN107771182A
(zh)
|
2015-05-29 |
2018-03-06 |
豪夫迈·罗氏有限公司 |
人源化抗埃博拉病毒糖蛋白抗体和使用方法
|
WO2016200835A1
(en)
|
2015-06-08 |
2016-12-15 |
Genentech, Inc. |
Methods of treating cancer using anti-ox40 antibodies and pd-1 axis binding antagonists
|
WO2016200836A1
(en)
|
2015-06-08 |
2016-12-15 |
Genentech, Inc. |
Methods of treating cancer using anti-ox40 antibodies
|
CN106267226A
(zh)
*
|
2015-06-09 |
2017-01-04 |
北京和理咨询有限公司 |
治疗骨肉瘤的雷公藤甲素衍生物及其制备方法
|
WO2016201394A1
(en)
|
2015-06-12 |
2016-12-15 |
Miltenyi Biotec Technology, Inc. |
Method to treat cancer with engineered t-cells
|
TW201709934A
(zh)
|
2015-06-15 |
2017-03-16 |
建南德克公司 |
抗體及免疫結合物
|
SI3310814T1
(sl)
|
2015-06-16 |
2023-11-30 |
F. Hoffmann - La Roche Ag |
HUMANIZIRANA IN AFINITETNO DOZORELA PROTITELESA PROTI FcRH5 IN METODE ZA NJIHOVO UPORABO
|
JP6996983B2
(ja)
|
2015-06-16 |
2022-02-21 |
ジェネンテック, インコーポレイテッド |
抗cll-1抗体及び使用方法
|
WO2016204966A1
(en)
|
2015-06-16 |
2016-12-22 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
CN107787331B
(zh)
|
2015-06-17 |
2022-01-11 |
豪夫迈·罗氏有限公司 |
抗her2抗体和使用方法
|
CN116726190A
(zh)
*
|
2015-06-20 |
2023-09-12 |
杭州多禧生物科技有限公司 |
澳瑞他汀类似物及其与细胞结合分子的共轭偶联物
|
CN114917361A
(zh)
|
2015-06-22 |
2022-08-19 |
拜耳医药股份有限公司 |
具有酶可裂解基团的抗体药物缀合物(adc)和抗体前药缀合物(apdc)
|
JP6905941B2
(ja)
|
2015-06-23 |
2021-07-21 |
バイエル ファーマ アクチエンゲゼルシャフト |
キネシンスピンドルタンパク質(ksp)阻害剤の抗b7h3抗体との抗体薬物複合体
|
BR112017024610A2
(pt)
|
2015-06-24 |
2018-07-31 |
F. Hoffmann-La Roche Ag |
anticorpos para receptor antitransferrina com afinidade especificada
|
KR20180021864A
(ko)
|
2015-06-29 |
2018-03-05 |
제넨테크, 인크. |
장기 이식에서 사용하기 위한 유형 ii 항-cd20 항체
|
DK3316909T3
(da)
|
2015-06-30 |
2023-11-13 |
Seagen Inc |
Anti-ntb-a-antistoffer og relaterede sammensætninger og fremgangsmåder
|
JP6892431B2
(ja)
|
2015-07-10 |
2021-06-23 |
ゲンマブ エー/エス |
癌治療用のaxl特異的抗体−薬物コンジュゲート
|
WO2015151081A2
(en)
|
2015-07-12 |
2015-10-08 |
Suzhou M-Conj Biotech Co., Ltd |
Bridge linkers for conjugation of a cell-binding molecule
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
WO2017019489A1
(en)
|
2015-07-24 |
2017-02-02 |
George Robert Pettit |
Quinstatin compounds
|
CN106380508A
(zh)
*
|
2015-07-28 |
2017-02-08 |
上海皓元生物医药科技有限公司 |
一种抗体偶联药物连接子的工业化生产方法
|
KR20180030917A
(ko)
|
2015-08-05 |
2018-03-26 |
얀센 바이오테크 인코포레이티드 |
항-cd154 항체 및 그의 사용 방법
|
SG10201913625XA
(en)
|
2015-08-07 |
2020-03-30 |
Imaginab Inc |
Antigen binding constructs to target molecules
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
US11197934B2
(en)
*
|
2015-09-17 |
2021-12-14 |
The Scripps Research Institute |
Dual variable domain immunoconjugates and uses thereof
|
EP3353198B1
(en)
|
2015-09-23 |
2020-06-17 |
Bristol-Myers Squibb Company |
Glypican-3binding fibronectin based scafflold molecules
|
BR112018005737A2
(pt)
|
2015-09-23 |
2018-10-09 |
Genentech Inc |
anticorpos, polinucleotídeo, vetor, célula hospedeira, método para produzir o anticorpo, para reduzir ou inibir a angiogênese, para tratar um distúrbio associado à angiogênese, para inibir a permeabilidade vascular, composição, conjugado de anticorpo, proteína de fusão, para identificar uma alteração de resíduos, utilização do anticorpo, utilização do conjugado e utilização da proteína
|
RU2757135C2
(ru)
|
2015-09-24 |
2021-10-11 |
АБВИТРО ЭлЭлСи |
Композиции антител к вич и способы их применения
|
IL298355A
(en)
|
2015-09-25 |
2023-01-01 |
Genentech Inc |
Anti-tigit antibodies and methods of use
|
IL258268B
(en)
|
2015-09-30 |
2022-09-01 |
Janssen Biotech Inc |
Agonist antibodies that specifically bind to human cd40 and methods of use
|
CA2992853A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies specific for pd1 and tim3
|
AR106189A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
MA43023A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Anticorps de récepteur de la transferrine humaine/anti-humaine cd20 bispécifique et leurs procédés d'utilisation
|
WO2017058808A1
(en)
|
2015-10-02 |
2017-04-06 |
Sirenas Llc |
Anti-cancer compounds and conjugates thereof
|
US20170247454A1
(en)
|
2015-10-02 |
2017-08-31 |
Hoffmann-La Roche Inc. |
Anti-pd1 antibodies and methods of use
|
WO2017062748A1
(en)
|
2015-10-07 |
2017-04-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Il-7r-alpha specific antibodies for treating acute lymphoblastic leukemia
|
JP6821688B2
(ja)
|
2015-10-09 |
2021-01-27 |
ミルテニー・バイオテク・テクノロジー・インコーポレイテッドMiltenyi Biotec Technology, Inc. |
キメラ抗原受容体および使用方法
|
WO2017060397A1
(en)
|
2015-10-09 |
2017-04-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of subjects suffering from melanoma metastases
|
WO2017060322A2
(en)
|
2015-10-10 |
2017-04-13 |
Bayer Pharma Aktiengesellschaft |
Ptefb-inhibitor-adc
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
WO2017067944A1
(en)
|
2015-10-19 |
2017-04-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of subjects suffering from triple negative breast cancer
|
MA45326A
(fr)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
HRP20220064T1
(hr)
|
2015-10-30 |
2022-04-15 |
F. Hoffmann - La Roche Ag |
Zglobno modificirani fragmenti protutijela i postupci za pripravu
|
EP3165237B1
(en)
*
|
2015-11-03 |
2018-12-19 |
Industrial Technology Research Institute |
Antibody-drug conjugate (adc) and method for forming the same
|
CA3004117A1
(en)
|
2015-11-03 |
2017-05-11 |
Janssen Biotech, Inc. |
Antibodies specifically binding pd-1 and their uses
|
WO2017079768A1
(en)
|
2015-11-08 |
2017-05-11 |
Genentech, Inc. |
Methods of screening for multispecific antibodies
|
CN106729743B
(zh)
|
2015-11-23 |
2021-09-21 |
四川科伦博泰生物医药股份有限公司 |
抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用
|
CA3006247A1
(en)
|
2015-11-25 |
2017-06-01 |
Legochem Biosciences, Inc. |
Conjugates comprising peptide groups and methods related thereto
|
WO2017089895A1
(en)
|
2015-11-25 |
2017-06-01 |
Legochem Biosciences, Inc. |
Antibody-drug conjugates comprising branched linkers and methods related thereto
|
CA3006242A1
(en)
|
2015-11-25 |
2017-06-01 |
Legochem Biosciences, Inc. |
Conjugates comprising self-immolative groups and methods related thereto
|
US10689458B2
(en)
|
2015-11-30 |
2020-06-23 |
Pfizer Inc. |
Site specific HER2 antibody drug conjugates
|
JP2019500327A
(ja)
*
|
2015-11-30 |
2019-01-10 |
アッヴィ・インコーポレイテッド |
抗huLRRC15抗体薬物コンジュゲート及びその使用方法
|
US11793880B2
(en)
|
2015-12-04 |
2023-10-24 |
Seagen Inc. |
Conjugates of quaternized tubulysin compounds
|
EP3383420B1
(en)
|
2015-12-04 |
2022-03-23 |
Seagen Inc. |
Conjugates of quaternized tubulysin compounds
|
CN108699136B
(zh)
|
2015-12-07 |
2022-03-18 |
Xencor股份有限公司 |
结合cd3和psma的异二聚抗体
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
IL257696B1
(en)
|
2015-12-09 |
2024-07-01 |
Hoffmann La Roche |
Antibody against CD20 type II to reduce the formation of antibodies against drugs
|
JP6088703B1
(ja)
|
2015-12-18 |
2017-03-01 |
中外製薬株式会社 |
抗c5抗体および使用方法
|
KR20180089433A
(ko)
|
2015-12-21 |
2018-08-08 |
브리스톨-마이어스 스큅 컴퍼니 |
부위-특이적 접합을 위한 변이체 항체
|
CN115554406A
(zh)
|
2016-01-07 |
2023-01-03 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-cd20组合
|
CN106943598A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-her2组合
|
CN106943597A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-egfr组合
|
CN108713026B
(zh)
|
2016-01-08 |
2023-01-06 |
美国全心医药生技股份有限公司 |
四价抗psgl-1抗体及其用途
|
JP2019505520A
(ja)
|
2016-01-13 |
2019-02-28 |
ゲンマブ エー/エス |
抗体およびその薬物コンジュゲートの製剤
|
US11583593B2
(en)
|
2016-01-14 |
2023-02-21 |
Synthis Therapeutics, Inc. |
Antibody-ALK5 inhibitor conjugates and their uses
|
RU2018130757A
(ru)
|
2016-01-27 |
2020-02-27 |
Сутро Биофарма, Инк. |
Конъюгаты антитела к cd74, композиции, содержащие конъюгаты антитела к cd74, и способы использования конъюгатов антитела к cd74
|
CN107029244B
(zh)
*
|
2016-02-04 |
2021-04-27 |
浙江昭华生物医药有限公司 |
抗her2抗体-药物偶联物及其应用
|
AU2017213826A1
(en)
|
2016-02-04 |
2018-08-23 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
SG11201806261XA
(en)
|
2016-02-17 |
2018-09-27 |
Seattle Genetics Inc |
Bcma antibodies and use of same to treat cancer and immunological disorders
|
CN107531680B
(zh)
*
|
2016-02-26 |
2020-09-11 |
江苏恒瑞医药股份有限公司 |
一种毒素及其中间体的制备方法
|
WO2017147597A1
(en)
|
2016-02-27 |
2017-08-31 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Peptide vaccines comprising self-assembling polymer nanoparticles
|
TW201740979A
(zh)
|
2016-02-29 |
2017-12-01 |
瑪德瑞高製藥公司 |
熱休克蛋白(hsp)90抑制劑藥物共軛物
|
EP4155415A1
(en)
|
2016-02-29 |
2023-03-29 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
WO2017151947A1
(en)
|
2016-03-02 |
2017-09-08 |
George Robert Pettit |
4-azapodophylotoxins compounds
|
JP2019514844A
(ja)
|
2016-03-04 |
2019-06-06 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
抗cd73抗体を用いた併用療法
|
AU2017228468B2
(en)
|
2016-03-04 |
2019-12-05 |
Genentech, Inc. |
Process for the preparation of an antibody-rifamycin conjugate
|
TW201808978A
(zh)
|
2016-03-08 |
2018-03-16 |
中央研究院 |
N-聚醣及其陣列之模組化合成方法
|
MA45324A
(fr)
|
2016-03-15 |
2019-01-23 |
Seattle Genetics Inc |
Polythérapie utilisant un adc-liv1 et un agent chimiothérapeutique
|
EP4302782A3
(en)
|
2016-03-15 |
2024-03-27 |
Mersana Therapeutics, Inc. |
Napi2b-targeted antibody-drug conjugates and methods of use thereof
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
KR102438140B1
(ko)
|
2016-03-22 |
2022-08-31 |
엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔 |
인간화 항-클라우딘-1 항체 및 이의 용도
|
CN108883195A
(zh)
|
2016-03-24 |
2018-11-23 |
拜耳制药股份公司 |
具有酶促可裂解基团的细胞毒性活性物质的前药
|
EP3433278A4
(en)
*
|
2016-03-25 |
2019-11-06 |
Seattle Genetics, Inc. |
PROCESS FOR THE PREPARATION OF PEGYLATED MEDICINE LINKS AND INTERMEDIATES THEREOF
|
MA45328A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Compositions acide nucléique-polypeptide et utilisations de celles-ci
|
JP2019515025A
(ja)
*
|
2016-04-04 |
2019-06-06 |
ラトガース ザ ステイト ユニバーシティー オブ ニュージャージー |
トポイソメラーゼ毒
|
EP3865511A1
(en)
|
2016-04-14 |
2021-08-18 |
F. Hoffmann-La Roche AG |
Anti-rspo3 antibodies and methods of use
|
KR20190003957A
(ko)
|
2016-04-15 |
2019-01-10 |
제넨테크, 인크. |
암 모니터링 및 치료 방법
|
KR102514317B1
(ko)
|
2016-04-15 |
2023-03-27 |
마크로제닉스, 인크. |
신규 b7-h3-결합 분자, 그것의 항체 약물 콘쥬게이트 및 그것의 사용 방법
|
JP6735355B2
(ja)
|
2016-04-15 |
2020-08-05 |
バイオアトラ、エルエルシー |
抗Axl抗体、抗体断片およびそれらの免疫コンジュゲートならびにそれらの使用
|
EP3443350B1
(en)
|
2016-04-15 |
2020-12-09 |
H. Hoffnabb-La Roche Ag |
Methods for monitoring and treating cancer
|
CA3019398A1
(en)
|
2016-04-26 |
2017-11-02 |
R.P. Scherer Technologies, Llc |
Antibody conjugates and methods of making and using the same
|
EP3889175A1
(en)
|
2016-05-02 |
2021-10-06 |
F. Hoffmann-La Roche AG |
The contorsbody - a single chain target binder
|
WO2017197045A1
(en)
|
2016-05-11 |
2017-11-16 |
Movassaghi Mohammad |
Convergent and enantioselective total synthesis of communesin analogs
|
EP3455252B1
(en)
|
2016-05-11 |
2022-02-23 |
F. Hoffmann-La Roche AG |
Modified anti-tenascin antibodies and methods of use
|
AU2017263568B2
(en)
|
2016-05-13 |
2024-01-18 |
Bioatla, Llc |
Anti-Ror2 antibodies, antibody fragments, their immunoconjugates and uses thereof
|
US20170348429A1
(en)
*
|
2016-05-17 |
2017-12-07 |
Abbvie Biotherapeutics Inc. |
ANTI-cMET ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE
|
PL3458101T3
(pl)
|
2016-05-20 |
2021-05-31 |
F. Hoffmann-La Roche Ag |
Koniugaty PROTAC-przeciwciało i sposoby ich stosowania
|
CN109313200B
(zh)
|
2016-05-27 |
2022-10-04 |
豪夫迈·罗氏有限公司 |
用于表征位点特异性抗体-药物缀合物的生物分析性方法
|
TW201902512A
(zh)
|
2016-06-02 |
2019-01-16 |
瑞士商赫孚孟拉羅股份公司 |
治療方法
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
EP4094778B1
(en)
|
2016-06-03 |
2024-05-15 |
Novacyte Therapeutics Company.,LTD |
Polymer linkers and their uses
|
EP3464280B1
(en)
|
2016-06-06 |
2021-10-06 |
F. Hoffmann-La Roche AG |
Silvestrol antibody-drug conjugates and methods of use
|
WO2017214322A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
JP2019524651A
(ja)
|
2016-06-08 |
2019-09-05 |
アッヴィ・インコーポレイテッド |
抗cd98抗体及び抗体薬物コンジュゲート
|
CA3027046A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-cd98 antibodies and antibody drug conjugates
|
SG10201914119TA
(en)
|
2016-06-08 |
2020-02-27 |
Abbvie Inc |
Anti-b7-h3 antibodies and antibody drug conjugates
|
US20200338209A1
(en)
|
2016-06-08 |
2020-10-29 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
KR20230054508A
(ko)
|
2016-06-14 |
2023-04-24 |
젠코어 인코포레이티드 |
이중특이적 체크포인트 억제제 항체
|
CA3027445A1
(en)
|
2016-06-15 |
2017-12-21 |
Bayer Pharma Aktiengesellschaft |
Specific antibody-drug-conjugates (adcs) with ksp inhibitors and anti-cd123-antibodies
|
US11617799B2
(en)
|
2016-06-27 |
2023-04-04 |
Tagworks Pharmaceuticals B.V. |
Cleavable tetrazine used in bio-orthogonal drug activation
|
CN116063545A
(zh)
|
2016-06-28 |
2023-05-05 |
Xencor股份有限公司 |
结合生长抑素受体2的异源二聚抗体
|
CN108472371B
(zh)
*
|
2016-07-05 |
2022-05-24 |
江苏恒瑞医药股份有限公司 |
Egfr抗体-药物偶联物及其在医药上的应用
|
KR102553195B1
(ko)
|
2016-07-29 |
2023-07-07 |
주노 쎄러퓨티크스 인코퍼레이티드 |
항-cd19 항체에 대한 항-이디오타입 항체
|
CN116251182A
(zh)
|
2016-08-05 |
2023-06-13 |
中外制药株式会社 |
用于预防或治疗il-8相关疾病的组合物
|
SG11201900699QA
(en)
|
2016-08-09 |
2019-02-27 |
Seattle Genetics Inc |
Drug conjugates with self-stabilizing linkers having improved physiochemical properties
|
CN106674347B
(zh)
*
|
2016-08-16 |
2019-12-13 |
滨州医学院 |
一种新型耳抑素抗体
|
WO2018039274A1
(en)
|
2016-08-22 |
2018-03-01 |
CHO Pharma Inc. |
Antibodies, binding fragments, and methods of use
|
JP7138094B2
(ja)
|
2016-08-25 |
2022-09-15 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
マクロファージ活性化剤と組み合わせた抗csf-1r抗体の間欠投与
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
EP3507304B1
(en)
|
2016-09-02 |
2024-04-03 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with duocars
|
WO2018045245A1
(en)
|
2016-09-02 |
2018-03-08 |
Sirenas Llc |
Cyclic peptide analogs and conjugates thereof
|
WO2018048975A1
(en)
|
2016-09-09 |
2018-03-15 |
Bristol-Myers Squibb Company |
Use of an anti-pd-1 antibody in combination with an anti-mesothelin antibody in cancer treatment
|
SG10201607778XA
(en)
|
2016-09-16 |
2018-04-27 |
Chugai Pharmaceutical Co Ltd |
Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
|
WO2018050878A1
(en)
|
2016-09-19 |
2018-03-22 |
F. Hoffmann-La Roche Ag |
Complement factor based affinity chromatography
|
JP6453826B2
(ja)
*
|
2016-09-28 |
2019-01-16 |
トヨタ自動車株式会社 |
摺動部材およびその製造方法
|
US10517958B2
(en)
|
2016-10-04 |
2019-12-31 |
Zymeworks Inc. |
Compositions and methods for the treatment of platinum-drug resistant cancer
|
EP3522933B1
(en)
|
2016-10-05 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Methods for preparing antibody drug conjugates
|
AU2017339517B2
(en)
|
2016-10-06 |
2024-03-14 |
Foundation Medicine, Inc. |
Therapeutic and diagnostic methods for cancer
|
JP7273453B2
(ja)
|
2016-10-14 |
2023-05-15 |
ゼンコア インコーポレイテッド |
IL-15/IL-15RアルファFc融合タンパク質およびPD-1抗体の断片を含む二重特異性ヘテロ二量体融合タンパク質
|
EA201990890A1
(ru)
|
2016-10-18 |
2019-10-31 |
|
Целевая доставка ингибиторов реутилизационного пути никотинамидадениндинуклеотида
|
JP7261158B2
(ja)
|
2016-10-19 |
2023-04-19 |
インベンラ, インコーポレイテッド |
抗体構築物
|
US11186635B2
(en)
|
2016-10-25 |
2021-11-30 |
Institut National De La Santé Et De La Recherché Médical (Inserm) |
Monoclonal antibodies binding to the CD160 transmembrane isoform
|
EP3532091A2
(en)
|
2016-10-29 |
2019-09-04 |
H. Hoffnabb-La Roche Ag |
Anti-mic antibidies and methods of use
|
KR20190070977A
(ko)
|
2016-11-01 |
2019-06-21 |
젠맵 비. 브이 |
폴리펩티드 변이체 및 그의 용도
|
KR20190074310A
(ko)
|
2016-11-08 |
2019-06-27 |
리제너론 파마슈티칼스 인코포레이티드 |
스테로이드 및 이의 단백질-접합체
|
JP7523907B2
(ja)
*
|
2016-11-14 |
2024-07-29 |
武田薬品工業株式会社 |
非成人のヒトに対する抗cd30抗体-薬物コンジュゲートの投与
|
KR102459469B1
(ko)
|
2016-11-14 |
2022-10-26 |
항저우 디에이씨 바이오테크 씨오, 엘티디 |
결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
|
WO2018093821A1
(en)
|
2016-11-15 |
2018-05-24 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
AU2017361887B2
(en)
|
2016-11-21 |
2019-08-15 |
Cureab Gmbh |
Anti-GP73 antibodies and immunoconjugates
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
JP7244987B2
(ja)
|
2016-12-14 |
2023-03-23 |
シージェン インコーポレイテッド |
多剤抗体薬物コンジュゲート
|
US10864279B2
(en)
|
2016-12-16 |
2020-12-15 |
Industrial Technology Research Institute |
Linker-drug and antibody-drug conjugate (ADC) employing the same
|
EP3558387B1
(de)
|
2016-12-21 |
2021-10-20 |
Bayer Pharma Aktiengesellschaft |
Spezifische antikörper-wirkstoff-konjugate (adcs) mit ksp-inhibitoren
|
KR102556826B1
(ko)
|
2016-12-21 |
2023-07-18 |
바이엘 파마 악티엔게젤샤프트 |
효소적으로 절단가능한 기를 갖는 항체 약물 접합체 (adc)
|
CA3047491A1
(en)
|
2016-12-21 |
2018-06-28 |
Bayer Aktiengesellschaft |
Prodrugs of cytotoxic active agents having enzymatically cleavable groups
|
CN110072553B
(zh)
|
2016-12-22 |
2023-09-15 |
豪夫迈·罗氏有限公司 |
在抗pd-l1/pd1治疗失败之后抗csf-1r抗体与抗pd-l1抗体组合对肿瘤的治疗
|
JP2020506716A
(ja)
|
2016-12-22 |
2020-03-05 |
ウニヴェルシタ・デリ・ストゥディ・マニャ・グレチア・カタンツァーロ |
Cd43の固有のシアログリコシル化がん関連エピトープを標的化するモノクローナル抗体
|
KR102085798B1
(ko)
|
2016-12-28 |
2020-03-06 |
주식회사 인투셀 |
베타-갈락토사이드가 도입된 자가-희생 기를 포함하는 화합물
|
CN110381980A
(zh)
|
2017-01-06 |
2019-10-25 |
艾维迪提生物科学有限责任公司 |
核酸-多肽组合物以及诱导外显子跳读的方法
|
CN117946283A
(zh)
|
2017-01-09 |
2024-04-30 |
莱蒂恩技术公司 |
用于用抗间皮素免疫治疗癌症的组合物和方法
|
CN110300765B
(zh)
|
2017-01-24 |
2024-08-23 |
依奈特制药公司 |
Nkp46结合剂
|
WO2018147960A1
(en)
|
2017-02-08 |
2018-08-16 |
Imaginab, Inc. |
Extension sequences for diabodies
|
SI3544636T1
(sl)
|
2017-02-08 |
2021-08-31 |
Adc Therapeutics Sa |
Konjugati pirolobenzodiazepin-protitelo
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
MY197534A
(en)
|
2017-02-10 |
2023-06-21 |
Genentech Inc |
Anti-tryptase antibodies, compositions thereof, and uses thereof
|
EP3579872A1
(en)
|
2017-02-10 |
2019-12-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of cancers associated with activation of the mapk pathway
|
AU2018220516A1
(en)
|
2017-02-16 |
2019-09-19 |
Sonnet BioTherapeutics, Inc. |
Albumin binding domain fusion proteins
|
CN116672463A
(zh)
*
|
2017-02-17 |
2023-09-01 |
浙江特瑞思药业股份有限公司 |
靶向cd20抗体偶联药物的制备方法、抗体偶联药物及其用途
|
CN108452319A
(zh)
*
|
2017-02-20 |
2018-08-28 |
浙江特瑞思药业股份有限公司 |
靶向cd20的抗体偶联药物制剂
|
SG11201907288RA
(en)
|
2017-02-28 |
2019-09-27 |
Seattle Genetics Inc |
Cysteine mutated antibodies for conjugation
|
US20180271996A1
(en)
|
2017-02-28 |
2018-09-27 |
Mersana Therapeutics, Inc. |
Combination therapies of her2-targeted antibody-drug conjugates
|
ES2953595T3
(es)
|
2017-03-01 |
2023-11-14 |
Hoffmann La Roche |
Procedimientos diagnósticos y terapéuticos para el cáncer
|
GB201703876D0
(en)
|
2017-03-10 |
2017-04-26 |
Berlin-Chemie Ag |
Pharmaceutical combinations
|
WO2018163131A1
(en)
|
2017-03-10 |
2018-09-13 |
Quiapeg Pharmaceuticals Ab |
Releasable conjugates
|
WO2018175988A1
(en)
|
2017-03-24 |
2018-09-27 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-cd33 immunotherapy
|
MX2019010769A
(es)
|
2017-03-24 |
2019-12-11 |
Seattle Genetics Inc |
Proceso para la preparacion de enlazadores de farmacos de glucuronidos y compuestos intermediarios de los mismos.
|
IL269535B1
(en)
|
2017-03-29 |
2024-07-01 |
Ligachem Biosciences Inc |
Meters drug pyrrolobenzodiazepine dimer and its ligand-binding conjugate compound
|
BR112019018767A2
(pt)
|
2017-04-03 |
2020-05-05 |
Hoffmann La Roche |
anticorpos, molécula de ligação ao antígeno biespecífica, um ou mais polinucleotídeos isolados, um ou mais vetores, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, usos, método para tratar uma doença em um indivíduo e invenção
|
CN110730908A
(zh)
|
2017-04-07 |
2020-01-24 |
朱诺治疗学股份有限公司 |
表达前列腺特异性膜抗原(psma)或其修饰形式的工程化细胞及相关方法
|
DK3612537T3
(da)
|
2017-04-18 |
2022-08-08 |
Medimmune Ltd |
Pyrrolobenzodiazepinkonjugater
|
WO2018195302A1
(en)
|
2017-04-19 |
2018-10-25 |
Bluefin Biomedicine, Inc. |
Anti-vtcn1 antibodies and antibody drug conjugates
|
EP3617221A4
(en)
*
|
2017-04-19 |
2021-04-14 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
CYTOTOXIN AND CONJUGATE, USES THEREOF AND MANUFACTURING PROCESSES THEREFORE
|
CN110536703B
(zh)
|
2017-04-20 |
2024-07-12 |
Adc治疗有限公司 |
使用抗axl抗体-药物缀合物的组合疗法
|
AU2018258687C1
(en)
|
2017-04-27 |
2023-02-02 |
Seagen Inc. |
Quaternized nicotinamide adenine dinucleotide salvage pathway inhibitor conjugates
|
US20220135670A1
(en)
|
2017-04-27 |
2022-05-05 |
Tesaro, Inc. |
Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof
|
CN118515666A
(zh)
|
2017-04-27 |
2024-08-20 |
博笛生物科技有限公司 |
2-氨基-喹啉衍生物
|
AU2018259856A1
(en)
|
2017-04-28 |
2019-11-14 |
Ajinomoto Co., Inc. |
Compound having substance that has affinity for soluble protein, cleavable moiety, and reactive group, or salt thereof
|
WO2018209239A1
(en)
|
2017-05-11 |
2018-11-15 |
Massachusetts Institute Of Technology |
Potent agelastatin derivatives as modulators for cancer invasion and metastasis
|
US11666657B2
(en)
|
2017-05-16 |
2023-06-06 |
Universite De Strasbourg |
Protein-drug conjugates and their use in the treatment of cancers
|
JP7364471B2
(ja)
*
|
2017-05-18 |
2023-10-18 |
レゲネロン ファーマシューティカルス,インコーポレーテッド |
シクロデキストリンタンパク質薬物コンジュゲート
|
CN116333129A
(zh)
|
2017-05-25 |
2023-06-27 |
百时美施贵宝公司 |
包含经修饰的重链恒定区的抗体
|
CN111010867B
(zh)
|
2017-05-30 |
2023-05-12 |
俄克拉何马大学董事会 |
抗双皮层蛋白样激酶1抗体及其使用方法
|
CA3064804A1
(en)
|
2017-06-14 |
2018-12-20 |
Adc Therapeutics Sa |
Dosage regimes for the administration of an anti-cd19 adc
|
WO2018234843A1
(en)
|
2017-06-22 |
2018-12-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF FIBROSIS WITH AGENTS CAPABLE OF INHIBITING THE ACTIVATION OF MOSES-ASSOCIATED INVARIANT T CELLS (MAIT)
|
EP3641826B1
(en)
|
2017-06-22 |
2023-12-06 |
Mersana Therapeutics, Inc. |
Methods of producing drug-carrying polymer scaffolds and protein-polymer-drug conjugates
|
JP7080501B2
(ja)
|
2017-06-23 |
2022-06-06 |
バーディー バイオファーマシューティカルズ インコーポレイテッド |
医薬品組成物
|
KR20200062161A
(ko)
|
2017-06-23 |
2020-06-03 |
벨로스바이오 인코포레이티드 |
Ror1 항체 면역접합체
|
JP2020529832A
(ja)
|
2017-06-30 |
2020-10-15 |
ゼンコア インコーポレイテッド |
IL−15/IL−15Rαおよび抗原結合ドメインを含む標的化ヘテロダイマーFc融合タンパク質
|
CN107375941A
(zh)
*
|
2017-07-17 |
2017-11-24 |
中国药科大学 |
一种抗人dll4单克隆抗体与海兔毒素衍生物mmae的偶联物
|
CN107296961A
(zh)
*
|
2017-07-17 |
2017-10-27 |
中国药科大学 |
一种抗人dll4单克隆抗体与阿霉素的偶联物
|
GB201711809D0
(en)
|
2017-07-21 |
2017-09-06 |
Governors Of The Univ Of Alberta |
Antisense oligonucleotide
|
MX2020000604A
(es)
|
2017-07-21 |
2020-09-10 |
Genentech Inc |
Métodos terapéuticos y de diagnóstico para el cáncer.
|
US20200207859A1
(en)
|
2017-07-26 |
2020-07-02 |
Sutro Biopharma, Inc. |
Methods of using anti-cd74 antibodies and antibody conjugates in treatment of t-cell lymphoma
|
EP3661964A1
(en)
|
2017-07-31 |
2020-06-10 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-cd19/cd20 immunotherapy
|
CN107652219B
(zh)
|
2017-08-14 |
2021-06-08 |
上海新理念生物医药科技有限公司 |
四马来酰亚胺型连接子及其应用
|
SI3668874T1
(sl)
|
2017-08-18 |
2022-04-29 |
Medimmune Limited |
Pirolobenzodiazepinski konjugati
|
TWI783890B
(zh)
|
2017-08-24 |
2022-11-11 |
丹麥商諾佛 儂迪克股份有限公司 |
Glp-1組成物及其用途
|
JP7035170B2
(ja)
|
2017-09-15 |
2022-03-14 |
レンティジェン・テクノロジー・インコーポレイテッド |
抗cd19免疫療法によりがんを処置するための組成物および方法
|
EP3684814A1
(en)
|
2017-09-18 |
2020-07-29 |
Sutro Biopharma, Inc. |
Anti-folate receptor alpha antibody conjugates and their uses
|
WO2019060542A2
(en)
|
2017-09-20 |
2019-03-28 |
Mersana Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR PREDICTING RESPONSE TO NAPI2B TARGETING THERAPY
|
US20200216463A1
(en)
|
2017-09-20 |
2020-07-09 |
Ph Pharma Co., Ltd. |
Thailanstatin analogs
|
CN107583058B
(zh)
*
|
2017-09-20 |
2020-09-18 |
厉保秋 |
一种t-2毒素-抗体缀合物及其用途
|
AU2018346507A1
(en)
|
2017-10-04 |
2020-04-23 |
Avidity Biosciences, Inc. |
Nucleic acid-polypeptide compositions and uses thereof
|
JP7356727B2
(ja)
|
2017-10-12 |
2023-10-05 |
慶應義塾 |
アクアポリン3(aqp3)の細胞外ドメインに特異的に結合する抗aqp3モノクローナル抗体、及びその使用
|
US10640508B2
(en)
|
2017-10-13 |
2020-05-05 |
Massachusetts Institute Of Technology |
Diazene directed modular synthesis of compounds with quaternary carbon centers
|
CN111630069B
(zh)
|
2017-10-13 |
2024-05-31 |
勃林格殷格翰国际有限公司 |
针对Thomsen-nouvelle(Tn)抗原的人抗体
|
CN111629735B
(zh)
|
2017-10-16 |
2024-05-17 |
莱蒂恩技术公司 |
用于用抗cd22免疫治疗来治疗癌症的组合物和方法
|
US20210190764A1
(en)
|
2017-10-20 |
2021-06-24 |
Chugai Seiyaku Kabushiki Kaisha |
Method for measuring cellular uptake of molecules
|
TW201922782A
(zh)
|
2017-10-24 |
2019-06-16 |
美商麥珍塔治療學股份有限公司 |
去除cd117+細胞之組合物及方法
|
CN111372947A
(zh)
|
2017-10-30 |
2020-07-03 |
豪夫迈·罗氏有限公司 |
在体内从单特异性抗体产生多特异性抗体的方法
|
EP3703688A2
(en)
|
2017-11-01 |
2020-09-09 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for b-cell maturation antigen
|
WO2019086395A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
Trifab-contorsbody
|
WO2019086394A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
The compbody - a multivalent target binder
|
CN107789631B
(zh)
*
|
2017-11-03 |
2021-03-16 |
合肥瀚科迈博生物技术有限公司 |
抗人ErbB2双表位抗体-药物偶联物及其应用
|
EP3707510B1
(en)
|
2017-11-06 |
2024-06-26 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for cancer
|
KR20200085828A
(ko)
|
2017-11-08 |
2020-07-15 |
젠코어 인코포레이티드 |
신규의 항-pd-1 서열을 사용한 이중특이적 및 단일특이적 항체
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
WO2019092148A1
(en)
|
2017-11-10 |
2019-05-16 |
Innate Pharma |
Antibodies with functionalized glutamine residues
|
WO2019096325A1
(zh)
*
|
2017-11-20 |
2019-05-23 |
江苏达骏生物科技有限公司 |
一种双酰胺复合物及其制备方法和用途
|
EP3717069A1
(en)
|
2017-11-27 |
2020-10-07 |
Purdue Pharma L.P. |
Humanized antibodies targeting human tissue factor
|
CN111655287A
(zh)
|
2017-11-30 |
2020-09-11 |
拜耳股份公司 |
Ildr2拮抗剂及其组合
|
WO2019108797A1
(en)
*
|
2017-11-30 |
2019-06-06 |
Seattle Genetics, Inc. |
Process for the preparation of drug linker compounds
|
CN111448213A
(zh)
|
2017-12-01 |
2020-07-24 |
西雅图基因公司 |
Cd47抗体及其用于治疗癌症的用途
|
CN111757892A
(zh)
|
2017-12-01 |
2020-10-09 |
西雅图基因公司 |
用于治疗乳腺癌的人源化抗liv1抗体
|
AU2018378812A1
(en)
|
2017-12-06 |
2020-07-09 |
Avidity Biosciences, Inc. |
Compositions and methods of treating muscle atrophy and myotonic dystrophy
|
CN113698414A
(zh)
|
2017-12-15 |
2021-11-26 |
四川科伦博泰生物医药股份有限公司 |
生物活性物偶联物及其制备方法和用途
|
EP3498293A1
(en)
|
2017-12-15 |
2019-06-19 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Treatment of monogenic diseases with an anti-cd45rc antibody
|
US11319355B2
(en)
|
2017-12-19 |
2022-05-03 |
Xencor, Inc. |
Engineered IL-2 Fc fusion proteins
|
US10894819B2
(en)
|
2017-12-20 |
2021-01-19 |
Lentigen Technology, Inc. |
Compositions and methods for treating HIV/AIDS with immunotherapy
|
US11667713B2
(en)
|
2017-12-28 |
2023-06-06 |
Chugai Seiyaku Kabushiki Kaisha |
Cytotoxicity-inducing therapeutic agent
|
MA50259A1
(fr)
|
2018-01-08 |
2021-07-29 |
Regeneron Pharma |
Stéroïdes et leurs conjugués-anticorps
|
CA3088649A1
(en)
|
2018-01-16 |
2019-07-25 |
Lakepharma, Inc. |
Bispecific antibody that binds cd3 and another target
|
CN111447939B
(zh)
*
|
2018-01-30 |
2024-07-12 |
四川科伦博泰生物医药股份有限公司 |
制备偶联物的方法
|
AR115360A1
(es)
|
2018-02-08 |
2021-01-13 |
Genentech Inc |
Moléculas de unión al antígeno y métodos de uso
|
JP2021513990A
(ja)
|
2018-02-20 |
2021-06-03 |
シージェン インコーポレイテッド |
疎水性アウリスタチンf化合物およびそのコンジュゲート
|
JP7391027B2
(ja)
|
2018-02-26 |
2023-12-04 |
ジェネンテック, インコーポレイテッド |
抗tigit及び抗pd-l1アンタゴニスト抗体による治療のための投薬
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
AU2019232652B2
(en)
|
2018-03-09 |
2022-04-21 |
Quiapeg Pharmaceuticals Ab |
Releasable antibody conjugates
|
DK3765525T5
(da)
|
2018-03-13 |
2024-08-26 |
Zymeworks Bc Inc |
Biparatopiske anti-her2-antistof-lægemiddelkonjugater og anvendelsesfremgangsmåder
|
US20200040103A1
(en)
|
2018-03-14 |
2020-02-06 |
Genentech, Inc. |
Anti-klk5 antibodies and methods of use
|
CN116327926A
(zh)
|
2018-03-15 |
2023-06-27 |
中外制药株式会社 |
对寨卡病毒具有交叉反应性的抗登革热病毒抗体及使用方法
|
KR20200135841A
(ko)
*
|
2018-03-23 |
2020-12-03 |
시애틀 지네틱스, 인크. |
고형 종양을 치료하기 위한 튜불린 교란제들을 포함하는 항체 약물 접합체들의 용도
|
SG11202008098TA
(en)
|
2018-03-28 |
2020-10-29 |
Axon Neuroscience Se |
Antibody-based methods of detecting and treating alzheimer's disease
|
JP7104458B2
(ja)
|
2018-04-02 |
2022-07-21 |
上海博威生物医薬有限公司 |
リンパ球活性化遺伝子-3(lag-3)結合抗体およびその使用
|
TW202011029A
(zh)
|
2018-04-04 |
2020-03-16 |
美商建南德克公司 |
偵測及定量fgf21之方法
|
US10982006B2
(en)
|
2018-04-04 |
2021-04-20 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
MX2020010729A
(es)
|
2018-04-13 |
2021-03-09 |
Genentech Inc |
Formulaciones de inmunoconjugado anti-cd79b estables.
|
EP3781194A4
(en)
*
|
2018-04-16 |
2022-10-12 |
Avelas Biosciences, Inc. |
COMPOSITIONS AND METHODS FOR SELECTIVE DELIVERY OF THERAPEUTIC AND IMAGING AGENTS
|
AR114789A1
(es)
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
JP2021520829A
(ja)
|
2018-04-18 |
2021-08-26 |
ゼンコア インコーポレイテッド |
IL−15/IL−15RA Fc融合タンパク質およびTIM−3抗原結合ドメインを含む、TIM−3標的化ヘテロ二量体融合タンパク質
|
EP3781599A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
EP4382167A3
(en)
|
2018-05-04 |
2024-08-28 |
Tagworks Pharmaceuticals B.V. |
Compounds comprising a linker for increasing transcyclooctene stability
|
AU2019262520A1
(en)
|
2018-05-04 |
2021-01-14 |
Tagworks Pharmaceuticals B.V. |
Tetrazines for high click conjugation yield in vivo and high click release yield
|
JP7460608B2
(ja)
|
2018-05-07 |
2024-04-02 |
ジェンマブ エー/エス |
抗pd-1抗体と抗組織因子抗体-薬物コンジュゲートとの組み合わせを用いるがんの治療方法
|
JP7519907B2
(ja)
|
2018-05-07 |
2024-07-22 |
ジェンマブ エー/エス |
抗pd-1抗体と抗組織因子抗体-薬物コンジュゲートとの組み合わせを用いるがんの治療方法
|
AU2019265703A1
(en)
|
2018-05-09 |
2020-11-19 |
Regeneron Pharmaceuticals, Inc. |
Anti-MSR1 antibodies and methods of use thereof
|
SG11202010443WA
(en)
|
2018-05-09 |
2020-11-27 |
Legochem Biosciences Inc |
Compositions and methods related to anti-cd19 antibody drug conjugates
|
ES2955511T3
(es)
|
2018-05-14 |
2023-12-04 |
Werewolf Therapeutics Inc |
Polipéptidos de interleucina 2 activables y métodos de uso de los mismos
|
MX2020012252A
(es)
|
2018-05-14 |
2021-04-28 |
Werewolf Therapeutics Inc |
Polipeptidos de interleucina 12 activables y metodos de uso de los mismos.
|
CN110507824A
(zh)
*
|
2018-05-21 |
2019-11-29 |
荣昌生物制药(烟台)有限公司 |
一种抗间皮素抗体及其抗体药物缀合物
|
MX2020012598A
(es)
|
2018-05-24 |
2021-05-27 |
Janssen Biotech Inc |
Agentes aglutinantes del psma y usos de estos.
|
US20210246187A1
(en)
|
2018-06-05 |
2021-08-12 |
King's College London |
Btnl3/8 targeting constructs for delivery of payloads to the gastrointestinal system
|
KR20210020015A
(ko)
|
2018-06-14 |
2021-02-23 |
아지노모토 가부시키가이샤 |
항체에 대한 친화성 물질 및 생체 직교성 관능기를 갖는 화합물 또는 이의 염
|
JP7413999B2
(ja)
|
2018-06-14 |
2024-01-16 |
味の素株式会社 |
抗体に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩
|
GB201809746D0
(en)
|
2018-06-14 |
2018-08-01 |
Berlin Chemie Ag |
Pharmaceutical combinations
|
JP7273858B2
(ja)
*
|
2018-06-15 |
2023-05-15 |
シャンハイ ミラコーケン インコーポレイティド |
癌を治療するための方法と材料
|
JP7468903B2
(ja)
|
2018-06-17 |
2024-04-16 |
エルアンドエル バイオファーマ カンパニー リミテッド |
Cldn18.2を標的とする抗体、二重特異性抗体、adc及びcarならびにその使用
|
EA202190059A1
(ru)
|
2018-06-18 |
2021-04-21 |
Байер Акциенгезельшафт |
Конъюгаты связующее-активное средство, направленные против cxcr5, имеющие ферментативно расщепляемые линкеры и улучшенный профиль активности
|
BR112020024078A2
(pt)
|
2018-06-29 |
2021-02-17 |
Boehringer Ingelheim International Gmbh |
anticorpos anti-cd40 para uso no tratamento de doença autoimune
|
BR112020026724A2
(pt)
|
2018-07-02 |
2021-03-30 |
Amgen Inc. |
Proteína de ligação ao antígeno anti-steap1
|
JP7335957B2
(ja)
*
|
2018-07-09 |
2023-08-30 |
シンシス セラピューティクス,インコーポレイテッド |
抗体-alk5阻害剤コンジュゲートおよびその使用
|
EP3820909B1
(en)
|
2018-07-11 |
2023-03-01 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Monoclonal antibody for the detection of the antiretroviral drug emtricitabine (ftc, 2',3'-dideoxy-5-fluoro-3'-thiacytidine)
|
WO2020014541A2
(en)
|
2018-07-13 |
2020-01-16 |
Il-2Rx, Inc. |
Compounds, compositions, methods, and uses for treating cancer and immunological disorders
|
WO2020023561A1
(en)
|
2018-07-23 |
2020-01-30 |
Magenta Therapeutics, Inc. |
Use of anti-cd5 antibody drug conjugate (adc) in allogeneic cell therapy
|
US20210324099A1
(en)
|
2018-08-10 |
2021-10-21 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-cd137 antigen-binding molecule and utilization thereof
|
CN113194999A
(zh)
|
2018-08-17 |
2021-07-30 |
梅尔莎纳医疗公司 |
NaPi2b靶向的聚合物抗体-药物缀合物及其使用方法
|
JP2021535920A
(ja)
|
2018-09-12 |
2021-12-23 |
キアペグ ファーマシューティカルズ アクチエボラグ |
放出可能なglp−1コンジュゲート
|
WO2020060944A1
(en)
|
2018-09-17 |
2020-03-26 |
Sutro Biopharma, Inc. |
Combination therapies with anti-folate receptor antibody conjugates
|
AU2019342099A1
(en)
|
2018-09-19 |
2021-04-08 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
EP3853251A1
(en)
|
2018-09-19 |
2021-07-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of cancers resistant to immune checkpoint therapy
|
CN113260630B
(zh)
|
2018-09-20 |
2024-05-24 |
莱蒂恩技术公司 |
用于用抗cd123免疫治疗来治疗癌症的组合物和方法
|
EP3626265A1
(en)
|
2018-09-21 |
2020-03-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-human cd45rc antibodies and uses thereof
|
US20210353764A1
(en)
|
2018-09-26 |
2021-11-18 |
Jiangsu Hengrui Medicine Co., Ltd. |
Ligand-drug conjugate of exatecan analogue, preparation method therefor and application thereof
|
AU2019350865A1
(en)
|
2018-09-26 |
2021-04-29 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with Anti-CD19/CD22 immunotherapy
|
EP3856764A4
(en)
|
2018-09-27 |
2022-11-02 |
Xilio Development, Inc. |
MASKED CYTOKINE POLYPEPTIDES
|
US20210347894A1
(en)
|
2018-09-30 |
2021-11-11 |
Jiangsu Hengrui Medicine Co., Ltd. |
Anti-b7h3 antibody-exatecan analog conjugate and medicinal use thereof
|
US11358999B2
(en)
|
2018-10-03 |
2022-06-14 |
Xencor, Inc. |
IL-12 heterodimeric Fc-fusion proteins
|
WO2020076849A1
(en)
|
2018-10-11 |
2020-04-16 |
The Scripps Research Institute |
Antibody compounds with reactive arginine and related antibody drug conjugates
|
CA3116324A1
(en)
|
2018-10-18 |
2020-04-23 |
Genentech, Inc. |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
EP3867267A1
(en)
*
|
2018-10-18 |
2021-08-25 |
FundaMental Pharma GmbH |
Novel means to modulate nmda receptor-mediated toxicity
|
WO2020086858A1
(en)
|
2018-10-24 |
2020-04-30 |
Genentech, Inc. |
Conjugated chemical inducers of degradation and methods of use
|
WO2020092385A1
(en)
|
2018-10-29 |
2020-05-07 |
Mersana Therapeutics, Inc. |
Cysteine engineered antibody-drug conjugates with peptide-containing linkers
|
MX2021004045A
(es)
|
2018-10-30 |
2021-06-04 |
Genmab As |
Metodos para tratar cancer con una combinacion de un anticuerpo anti factor de crecimiento endotelial vascular (vegf) y un conjugado de anticuerpo anti factor tisular-farmaco.
|
CN113227124A
(zh)
|
2018-10-31 |
2021-08-06 |
味之素株式会社 |
具有针对抗体的亲和性物质、切割性部分及反应性基团的化合物或其盐
|
US20220025058A1
(en)
|
2018-11-06 |
2022-01-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of acute myeloid leukemia by eradicating leukemic stem cells
|
CN113348177A
(zh)
|
2018-11-28 |
2021-09-03 |
百时美施贵宝公司 |
包含经修饰的重链恒定区的抗体
|
CN113412119A
(zh)
|
2018-11-30 |
2021-09-17 |
莱蒂恩技术公司 |
用于用抗cd38免疫治疗来治疗癌症的组合物和方法
|
JP7389803B2
(ja)
|
2018-11-30 |
2023-11-30 |
ブリストル-マイヤーズ スクイブ カンパニー |
グルタミンを含有する軽鎖c末端に伸長部分を含む抗体およびそのコンジュゲートならびにその方法および用途
|
AU2018451747A1
(en)
|
2018-12-06 |
2021-06-17 |
F. Hoffmann-La Roche Ag |
Combination therapy of diffuse large B-cell lymphoma comprising an anti-CD79b immunoconjugates, an alkylating agent and an anti-CD20 antibody
|
JP2022513198A
(ja)
|
2018-12-10 |
2022-02-07 |
ジェネンテック, インコーポレイテッド |
Fc含有タンパク質への部位特異的コンジュゲーションのための光架橋性ペプチド
|
US20220031860A1
(en)
|
2018-12-12 |
2022-02-03 |
Bristol-Myers Squibb Company |
Antibodies modified for transglutaminase conjugation, conjugates thereof, and methods and uses
|
US20220064260A1
(en)
|
2018-12-14 |
2022-03-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Isolated mhc-derived human peptides and uses thereof for stimulating and activating the suppressive function of cd8+cd45rclow tregs
|
CN113227131A
(zh)
|
2018-12-20 |
2021-08-06 |
豪夫迈·罗氏有限公司 |
经修饰的抗体Fc及其使用方法
|
WO2020127968A1
(en)
|
2018-12-20 |
2020-06-25 |
Marino Stephen F |
Protein-drug conjugate comprising a monomeric form of proteinase 3
|
EP3898693A4
(en)
|
2018-12-21 |
2022-09-21 |
Avidity Biosciences, Inc. |
ANTI-TRANSFERRIN RECEPTOR ANTIBODIES AND USES THEREOF
|
MX2021007768A
(es)
|
2018-12-26 |
2021-08-24 |
Xilio Dev Inc |
Anticuerpos anti-ctla4 y metodos de uso de los mismos.
|
CA3126359A1
(en)
|
2019-01-22 |
2020-07-30 |
Genentech, Inc. |
Immunoglobulin a antibodies and methods of production and use
|
CN113329770A
(zh)
|
2019-01-24 |
2021-08-31 |
中外制药株式会社 |
新型癌抗原及所述抗原的抗体
|
AR119683A1
(es)
|
2019-01-29 |
2022-01-05 |
Juno Therapeutics Inc |
Anticuerpos y receptores de antígeno quimérico específicos para receptor huérfano 1 similar a receptor de tirosina quinasa (ror1)
|
KR20210124308A
(ko)
|
2019-01-30 |
2021-10-14 |
트루바인딩 아이엔씨. |
항-gal3 항체 및 이의 용도
|
SG11202107551WA
(en)
|
2019-02-05 |
2021-08-30 |
Seagen Inc |
Anti-cd228 antibodies and antibody-drug conjugates
|
MX2021010313A
(es)
|
2019-02-27 |
2021-09-23 |
Genentech Inc |
Dosificacion para el tratamiento con anticuerpos anti-tigit y anti-cd20 o anti-cd38.
|
WO2020180726A1
(en)
|
2019-03-01 |
2020-09-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
CA3132660A1
(en)
|
2019-03-06 |
2020-09-10 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with self-driving chimeric antigen receptors
|
KR20210141555A
(ko)
|
2019-03-14 |
2021-11-23 |
제넨테크, 인크. |
Her2xcd3 이중특이적 항체 및 항-her2 mab를 병용한 암의 치료
|
WO2020213084A1
(en)
|
2019-04-17 |
2020-10-22 |
Keio University |
Anti aqp3 monoclonal antibody specifically binding to extracellular domain of aquaporin 3 (aqp3) and use thereof
|
AU2020259404A1
(en)
|
2019-04-19 |
2021-09-23 |
Janssen Biotech, Inc. |
Methods of treating prostate cancer with an anti- PSMA/CD3 antibody
|
KR20220002967A
(ko)
|
2019-04-19 |
2022-01-07 |
제넨테크, 인크. |
항 mertk 항체 및 이의 사용 방법
|
JP2022530026A
(ja)
|
2019-04-24 |
2022-06-27 |
ハイデルベルク ファルマ リサーチ ゲゼルシャフト ミット ベシュレンクテル ハフツング |
アマトキシン抗体薬物複合体及びその使用
|
EP3962951A1
(en)
|
2019-05-03 |
2022-03-09 |
Sutro Biopharma, Inc. |
Anti-bcma antibody conjugates
|
CN110283766B
(zh)
*
|
2019-05-13 |
2020-12-18 |
华中科技大学 |
一种重组卡介苗及其构建与应用
|
JP2022532217A
(ja)
|
2019-05-14 |
2022-07-13 |
ウェアウルフ セラピューティクス, インコーポレイテッド |
分離部分及びその使用方法
|
EP3968993A1
(en)
|
2019-05-14 |
2022-03-23 |
F. Hoffmann-La Roche AG |
Methods of using anti-cd79b immunoconjugates to treat follicular lymphoma
|
US20230002481A1
(en)
|
2019-05-15 |
2023-01-05 |
Chugai Seiyaku Kabushiki Kaisha |
An antigen-binding molecule, a pharmaceutical composition, and a method
|
AU2020283027A1
(en)
|
2019-05-30 |
2021-12-23 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-BCMA immunotherapy
|
WO2020247054A1
(en)
|
2019-06-05 |
2020-12-10 |
Massachusetts Institute Of Technology |
Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof
|
TW202112801A
(zh)
|
2019-06-05 |
2021-04-01 |
美商西雅圖遺傳學公司 |
純化遮蔽抗體之方法
|
WO2020247572A1
(en)
|
2019-06-05 |
2020-12-10 |
Seattle Genetics, Inc. |
Masked antibody formulations
|
AU2020289464A1
(en)
|
2019-06-06 |
2022-01-20 |
Avidity Biosciences, Inc. |
Nucleic acid-polypeptide compositions and uses thereof
|
BR112021024406A2
(pt)
|
2019-06-06 |
2022-04-19 |
Jiangsu Hansoh Pharmaceutical Group Co Ltd |
Conjugado anticorpo-fármaco anti-b7-h4 e uso medicinal do mesmo
|
CA3142337A1
(en)
|
2019-06-06 |
2020-12-10 |
Avidity Biosciences, Inc. |
Una amidites and uses thereof
|
IL289094A
(en)
|
2019-06-17 |
2022-02-01 |
Tagworks Pharmaceuticals B V |
Tetrazines for increasing the speed and yield of the "click release" reaction
|
EP4382129A3
(en)
|
2019-06-17 |
2024-07-03 |
Tagworks Pharmaceuticals B.V. |
Compounds for fast and efficient click release
|
WO2020256721A1
(en)
*
|
2019-06-19 |
2020-12-24 |
Synthis, Llc |
Antib0dy-alk5 inhibitor conjugates and their uses
|
KR20220031054A
(ko)
|
2019-07-02 |
2022-03-11 |
더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 |
Egfrviii에 결합하는 단일클론 항체 및 이의 용도
|
CN114174341A
(zh)
|
2019-07-08 |
2022-03-11 |
英凯尔生物科技有限责任公司 |
抗丝氨酸蛋白酶抑制剂kazal(spik)抗体、免疫缀合物和使用方法
|
JP7359864B2
(ja)
|
2019-07-10 |
2023-10-11 |
中外製薬株式会社 |
クローディン6結合分子およびその使用
|
US20220273809A1
(en)
|
2019-07-19 |
2022-09-01 |
Genmab A/S |
Axl antibody-drug conjugates for use in treating cancer
|
MX2022000853A
(es)
|
2019-07-22 |
2022-03-17 |
Seagen Inc |
Anticuerpos anti-liv1 humanizados para el tratamiento de cancer.
|
WO2021018168A1
(zh)
|
2019-07-30 |
2021-02-04 |
上海翰森生物医药科技有限公司 |
抗bcma抗体、其抗原结合片段及其医药用途
|
US20220289859A1
(en)
|
2019-08-06 |
2022-09-15 |
Glaxosmithkline Intellectual Property Development Limited |
Biopharmacuetical Compositions and Related Methods
|
CA3076712C
(en)
|
2019-08-07 |
2022-06-21 |
Mabplex International, Ltd. |
Antibody-drug conjugates and uses thereof
|
TW202120551A
(zh)
|
2019-08-12 |
2021-06-01 |
美商普瑞諾生物科技公司 |
藉由adcc靶向cd39表現細胞促進及增強t細胞介導免疫反應之方法及組合物
|
KR20210028544A
(ko)
|
2019-09-04 |
2021-03-12 |
주식회사 레고켐 바이오사이언스 |
인간 ror1에 대한 항체를 포함하는 항체 약물 접합체 및 이의 용도
|
KR20220080098A
(ko)
|
2019-09-11 |
2022-06-14 |
아임케어 바이오테크, 엘엘씨. |
항-세린 프로테아제 억제제 카잘(spik) 항체의 에피토프
|
WO2021055306A1
(en)
|
2019-09-16 |
2021-03-25 |
Bristol-Myers Squibb Company |
Dual capture method for analysis of antibody-drug conjugates
|
BR112022004913A2
(pt)
|
2019-09-18 |
2022-06-07 |
Baili Bio Chengdu Pharmaceutical Co Ltd |
Derivado de camptotecina e conjugado do mesmo
|
EP4031186A1
(en)
|
2019-09-19 |
2022-07-27 |
Seagen Inc. |
Selective drug release from internalized conjugates of biologically active compounds
|
US20220362397A1
(en)
|
2019-09-26 |
2022-11-17 |
Nof Corporation |
Heterobifunctional monodispersed polyethylene glycol having peptide linker
|
JP2022548978A
(ja)
|
2019-09-27 |
2022-11-22 |
ジェネンテック, インコーポレイテッド |
薬抗tigit及び抗pd-l1アンタゴニスト抗体を用いた処置のための投薬
|
EP3828196A4
(en)
|
2019-09-29 |
2022-04-27 |
MabPlex International Co., Ltd. |
METHOD FOR PREPARING AN ANTIBODY-DRUG CONJUGATE INTERMEDIATE BY MEANS OF AN ACID METHOD AND USE THEREOF
|
EP4017542A1
(en)
|
2019-10-04 |
2022-06-29 |
Tae Life Sciences |
Antibody compositions comprising fc mutations and site-specific conjugation properties
|
AR120147A1
(es)
|
2019-10-04 |
2022-02-02 |
Seattle Genetics Inc |
Anticuerpos anti-pd-l1 y conjugados anticuerpo-fármaco
|
WO2021064184A1
(en)
|
2019-10-04 |
2021-04-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
WO2021072265A1
(en)
|
2019-10-10 |
2021-04-15 |
Kodiak Sciences Inc. |
Methods of treating an eye disorder
|
TW202122114A
(zh)
|
2019-10-18 |
2021-06-16 |
美商建南德克公司 |
使用抗CD79b 免疫偶聯物治療彌漫性大B 細胞淋巴瘤的方法
|
MX2022005400A
(es)
|
2019-11-06 |
2022-05-24 |
Genentech Inc |
Metodos de diagnostico y terapeuticos para el tratamiento de canceres hematologicos.
|
JP2023500888A
(ja)
|
2019-11-07 |
2023-01-11 |
ジェンマブ エー/エス |
抗pd-1抗体と抗組織因子抗体-薬物コンジュゲートとの組み合わせを用いるがんの治療方法
|
TW202131954A
(zh)
|
2019-11-07 |
2021-09-01 |
丹麥商珍美寶股份有限公司 |
利用鉑類劑與抗組織因子抗體-藥物共軛體之組合來治療癌症之方法
|
BR112022009110A2
(pt)
|
2019-11-14 |
2022-07-26 |
Werewolf Therapeutics Inc |
Polipeptídeos de citocina ativáveis e métodos de uso destes
|
RU2729192C1
(ru)
*
|
2019-11-22 |
2020-08-05 |
Общество с ограниченной ответственностью "Изварино Фарма" |
Конъюгат монометил ауристатина е для получения композиции для лечения рака предстательной железы
|
CN110964043B
(zh)
*
|
2019-12-02 |
2022-05-24 |
广州中医药大学(广州中医药研究院) |
一种瓜氨酸探针化合物及其应用
|
CA3163897A1
(en)
|
2019-12-06 |
2021-06-10 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to bcma-targeted binding domains and related compositions and methods
|
WO2021113780A1
(en)
|
2019-12-06 |
2021-06-10 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to gprc5d-targeted binding domains and related compositions and methods
|
JP2023506187A
(ja)
|
2019-12-09 |
2023-02-15 |
シージェン インコーポレイテッド |
Liv1-adcおよびpd-1アンタゴニストとの併用療法
|
JP2023505708A
(ja)
|
2019-12-12 |
2023-02-10 |
江蘇恒瑞医薬股▲ふん▼有限公司 |
抗クローディン抗体薬物複合体及びその医薬用途
|
PE20221511A1
(es)
|
2019-12-13 |
2022-10-04 |
Genentech Inc |
Anticuerpos anti-ly6g6d y metodos de uso
|
CA3163130A1
(en)
|
2019-12-16 |
2021-06-24 |
Jiangsu Hengrui Medicine Co., Ltd. |
Anti-cea antibody-exatecan analog conjugate and pharmaceutical use thereof
|
US20220372162A1
(en)
|
2019-12-18 |
2022-11-24 |
TeneoFour, Inc. |
Pct/us2020/066088
|
CR20220357A
(es)
|
2019-12-27 |
2022-08-24 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti antígeno-4 asociado al linfocito t citotóxico (ctla-4) y uso del mismo
|
TW202138388A
(zh)
|
2019-12-30 |
2021-10-16 |
美商西根公司 |
以非海藻糖苷化抗-cd70抗體治療癌症之方法
|
CN113597434B
(zh)
|
2019-12-31 |
2022-07-01 |
北京质肽生物医药科技有限公司 |
Glp-1和gdf15的融合蛋白以及其缀合物
|
AU2021205893A1
(en)
|
2020-01-08 |
2022-06-23 |
Synthis Therapeutics, Inc. |
ALK5 inhibitor conjugates and uses thereof
|
CN110818795B
(zh)
|
2020-01-10 |
2020-04-24 |
上海复宏汉霖生物技术股份有限公司 |
抗tigit抗体和使用方法
|
CN115322794A
(zh)
|
2020-01-11 |
2022-11-11 |
北京质肽生物医药科技有限公司 |
Glp-1和fgf21的融合蛋白的缀合物
|
WO2021147993A1
(zh)
|
2020-01-22 |
2021-07-29 |
江苏恒瑞医药股份有限公司 |
抗trop-2抗体-依喜替康类似物偶联物及其医药用途
|
AU2021210079A1
(en)
|
2020-01-22 |
2022-08-25 |
Jiangsu Hengrui Medicine Co., Ltd. |
Drug conjugate of Eribulin derivative, preparation method therefor and application thereof in medicine
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
WO2022050954A1
(en)
|
2020-09-04 |
2022-03-10 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
TW202144395A
(zh)
|
2020-02-12 |
2021-12-01 |
日商中外製藥股份有限公司 |
用於癌症之治療的抗cd137抗原結合分子
|
CA3165359A1
(en)
|
2020-02-18 |
2021-07-22 |
Dorthe Kot Engelund |
Glp-1 compositions and uses thereof
|
US20230095053A1
(en)
|
2020-03-03 |
2023-03-30 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use
|
PE20230252A1
(es)
|
2020-03-13 |
2023-02-07 |
Genentech Inc |
Anticuerpos anti-interleucina-33 y sus usos de estos
|
CR20220524A
(es)
|
2020-03-19 |
2022-12-02 |
Genentech Inc |
Anticuerpos anti-tgf-beta con selectividad de isoforma y métodos de uso
|
TW202144572A
(zh)
|
2020-03-19 |
2021-12-01 |
美商亞維代堤生物科學公司 |
治療臉肩胛肱骨肌肉失養症之組合物及方法
|
CN115103858A
(zh)
|
2020-03-25 |
2022-09-23 |
江苏恒瑞医药股份有限公司 |
一种抗体药物偶联物的制备方法
|
CA3175733A1
(en)
|
2020-03-25 |
2021-09-30 |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
Pharmaceutical composition comprising antibody drug conjugate and use thereof
|
CA3177279A1
(en)
|
2020-03-25 |
2021-09-30 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Anti-psma antibody-exatecan analogue conjugate and medical use thereof
|
EP4129333A4
(en)
*
|
2020-03-27 |
2024-06-12 |
PhotoQ3 Inc. |
PHARMACEUTICAL MEDICINAL PRODUCT FOR THE DESTROYING OF TUMOR CELLS
|
EP4126066A4
(en)
|
2020-03-27 |
2024-04-24 |
Avidity Biosciences, Inc. |
COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHY
|
CN115698717A
(zh)
|
2020-04-03 |
2023-02-03 |
基因泰克公司 |
癌症的治疗和诊断方法
|
BR112022020332A2
(pt)
|
2020-04-10 |
2022-12-13 |
Seagen Inc |
Composto conjugado anticorpo-droga, composição, método de tratamento de câncer e de um distúrbio autoimune
|
JP2023522930A
(ja)
|
2020-04-24 |
2023-06-01 |
ジェネンテック, インコーポレイテッド |
抗CD79b免疫抱合体の使用方法
|
CN115885050A
(zh)
|
2020-04-28 |
2023-03-31 |
基因泰克公司 |
用于非小细胞肺癌免疫疗法的方法和组合物
|
IL297830A
(en)
|
2020-05-03 |
2023-01-01 |
Levena Suzhou Biopharma Co Ltd |
Anti-drug compounds (adcs) comprising an anti-trop-2 antibody, compounds comprising such adcs, as well as methods for their production and use
|
US11919956B2
(en)
|
2020-05-14 |
2024-03-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
|
WO2021234110A1
(en)
|
2020-05-20 |
2021-11-25 |
Institut Curie |
Single domain antibodies and their use in cancer therapies
|
US20230235080A1
(en)
|
2020-06-03 |
2023-07-27 |
Bionecure Therapeutics, Inc. |
Trophoblast cell-surface antigen-2 (trop-2) antibodies
|
MX2022015695A
(es)
|
2020-06-08 |
2023-03-21 |
Baili Bio Chengdu Pharmaceutical Co Ltd |
Medicina de camptotecina con alta unidad de conexion hidrofila y conjugado de la misma.
|
EP4163294A4
(en)
|
2020-06-09 |
2024-07-24 |
Ajinomoto Kk |
MODIFIED FERRITIN AND METHOD FOR PRODUCING SAME
|
WO2021252803A1
(en)
|
2020-06-11 |
2021-12-16 |
Genentech, Inc. |
Nanolipoprotein-polypeptide conjugates and compositions, systems, and methods using same
|
CN115698719A
(zh)
|
2020-06-12 |
2023-02-03 |
基因泰克公司 |
用于癌症免疫疗法的方法和组合物
|
KR20230024368A
(ko)
|
2020-06-18 |
2023-02-20 |
제넨테크, 인크. |
항-tigit 항체 및 pd-1 축 결합 길항제를 사용한 치료
|
CN116829581A
(zh)
|
2020-06-22 |
2023-09-29 |
莱蒂恩技术公司 |
用于用tslpr-cd19或tslpr-cd22免疫治疗来治疗癌症的组合物和方法
|
AU2021299947A1
(en)
|
2020-06-29 |
2022-12-22 |
Genmab A/S |
Anti-tissue factor antibody-drug conjugates and their use in the treatment of cancer
|
EP4180422A4
(en)
|
2020-07-10 |
2024-01-24 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
SULFONYL BENZAMIDE DERIVATIVE AND CONJUGATE THEREOF, PROCESS THEREOF AND USE THEREOF
|
WO2022015726A1
(en)
|
2020-07-13 |
2022-01-20 |
Genentech, Inc. |
Cell-based methods for predicting polypeptide immunogenicity
|
JP2023535409A
(ja)
|
2020-07-21 |
2023-08-17 |
ジェネンテック, インコーポレイテッド |
Brm分解の抗体コンジュゲート化化学的誘導物質及びbrm分解の方法
|
CN115698079A
(zh)
|
2020-07-27 |
2023-02-03 |
上海拓界生物医药科技有限公司 |
抗cd79b抗体药物偶联物、其制备方法及其医药用途
|
JPWO2022025184A1
(el)
|
2020-07-29 |
2022-02-03 |
|
|
US20230323299A1
(en)
|
2020-08-03 |
2023-10-12 |
Inserm (Institut National De La Santé Et De La Recherch Médicale) |
Population of treg cells functionally committed to exert a regulatory activity and their use for adoptive therapy
|
JP2023537714A
(ja)
|
2020-08-04 |
2023-09-05 |
シージェン インコーポレイテッド |
抗cd228抗体及び抗体薬物コンジュゲート
|
EP4192868A1
(en)
|
2020-08-05 |
2023-06-14 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to ror1-targeted binding domains and related compositions and methods
|
EP4192942A1
(en)
|
2020-08-07 |
2023-06-14 |
Genentech, Inc. |
T cell-based methods for predicting polypeptide immunogenicity
|
EP4192854A1
(en)
|
2020-08-07 |
2023-06-14 |
Genentech, Inc. |
Flt3 ligand fusion proteins and methods of use
|
CN112062855B
(zh)
|
2020-08-26 |
2024-08-30 |
北京天诺健成医药科技有限公司 |
一种含有衔接器的药物治疗剂的开发和应用
|
EP4213939A1
(en)
|
2020-09-21 |
2023-07-26 |
Boehringer Ingelheim International GmbH |
Use of anti-cd40 antibodies for treatment of inflammatory conditions
|
US20220112274A1
(en)
|
2020-09-28 |
2022-04-14 |
Seagen Inc. |
Humanized anti-liv1 antibodies for the treatment of cancer
|
IL301658A
(en)
|
2020-09-30 |
2023-05-01 |
Jiangsu Hengrui Pharmaceuticals Co Ltd |
Drug compound consisting of antibody-drug conjugate and use of drug composition
|
CN114729060B
(zh)
|
2020-09-30 |
2022-11-25 |
北京质肽生物医药科技有限公司 |
多肽缀合物和使用方法
|
IL301547A
(en)
|
2020-10-05 |
2023-05-01 |
Genentech Inc |
Dosage for treatment with bispecific anti-FCRH5/anti-CD3 antibodies
|
AU2021361938A1
(en)
|
2020-10-12 |
2023-05-25 |
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. |
Deuterated camptothecin derivative and antibody-drug conjugate thereof
|
AU2021359457A1
(en)
|
2020-10-12 |
2023-05-11 |
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. |
Camptothecin derivative and its ligand-drug conjugate
|
TW202304983A
(zh)
|
2020-10-14 |
2023-02-01 |
大陸商江蘇恆瑞醫藥股份有限公司 |
抗her3抗體和抗her3抗體藥物偶聯物及其醫藥用途
|
WO2022079270A1
(en)
|
2020-10-16 |
2022-04-21 |
Université D'aix-Marseille |
Anti-gpc4 single domain antibodies
|
DK4103236T3
(en)
|
2020-10-27 |
2023-11-13 |
Elucida Oncology Inc |
Folate receptor targeted nanoparticle drug conjugates and uses thereof
|
KR20230095113A
(ko)
|
2020-11-04 |
2023-06-28 |
제넨테크, 인크. |
항-cd20/항-cd3 이중특이적 항체들과 항-cd79b 항체 약물 접합체들을 이용한 치료를 위한 투약
|
AU2021374592A1
(en)
|
2020-11-04 |
2023-06-01 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
AU2021374590A1
(en)
|
2020-11-04 |
2023-06-01 |
Genentech, Inc. |
Subcutaneous dosing of anti-cd20/anti-cd3 bispecific antibodies
|
EP4240397A1
(en)
|
2020-11-05 |
2023-09-13 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-cd19/cd22 immunotherapy
|
KR20230104659A
(ko)
|
2020-11-08 |
2023-07-10 |
씨젠 인크. |
면역 세포 억제제를 이용한 조합-요법 항체 약물 접합체
|
CN112402616A
(zh)
*
|
2020-11-23 |
2021-02-26 |
荣昌生物制药(烟台)股份有限公司 |
一种含环丙沙星和抗体药物偶联物的药物组合物及其应用
|
CN114524878B
(zh)
|
2020-11-23 |
2024-08-02 |
康诺亚生物医药科技(成都)有限公司 |
一种双特异性抗体及其用途
|
CR20230283A
(es)
|
2020-11-24 |
2023-07-27 |
Novartis Ag |
Anticuerpos anti-cd48, conjugados de anticuerpo-fármaco, y usos de los mismos
|
CA3196198A1
(en)
|
2020-11-25 |
2022-06-02 |
Manel KRAIEM |
Treatment of cancer
|
CN114573703A
(zh)
|
2020-12-02 |
2022-06-03 |
康诺亚生物医药科技(成都)有限公司 |
一种t细胞衔接器治疗剂的开发和应用
|
CN114573702A
(zh)
|
2020-12-02 |
2022-06-03 |
康诺亚生物医药科技(成都)有限公司 |
一种新型肿瘤衔接器治疗药物的开发和应用
|
TW202237638A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
烏苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
CN114685657B
(zh)
|
2020-12-31 |
2024-08-16 |
康诺亚生物医药科技(成都)有限公司 |
一种功能增强型抗体阻断剂的开发及其应用
|
IL304031A
(en)
|
2021-01-14 |
2023-08-01 |
Inst Curie |
Variants of single-domain HER2 antibodies and their chimeric antigenic receptors
|
WO2022154116A1
(ja)
|
2021-01-18 |
2022-07-21 |
味の素株式会社 |
化合物またはその塩、およびそれらにより得られる抗体
|
CA3208290A1
(en)
|
2021-01-18 |
2022-07-21 |
Ajinomoto Co., Inc. |
Compound or salt thereof, and antibody obtained by using the same
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
CN116917326A
(zh)
|
2021-01-22 |
2023-10-20 |
博泰康医药公司 |
抗her-2/trop-2构建体及其用途
|
KR20230137393A
(ko)
|
2021-01-28 |
2023-10-04 |
얀센 바이오테크 인코포레이티드 |
Psma 결합 단백질 및 이의 용도
|
TW202241508A
(zh)
|
2021-01-29 |
2022-11-01 |
美商艾歐凡斯生物治療公司 |
細胞介素相關之腫瘤浸潤性淋巴球組合物及方法
|
WO2022166779A1
(zh)
|
2021-02-04 |
2022-08-11 |
上海森辉医药有限公司 |
糖皮质激素受体激动剂的药物偶联物及其在医药上的应用
|
CA3208365A1
(en)
|
2021-02-15 |
2022-08-18 |
Chantal KUHN |
Cell therapy compositions and methods for modulating tgf-b signaling
|
EP4294453A1
(en)
|
2021-02-16 |
2023-12-27 |
Glykos Finland Oy |
Linker-payloads and conjugates thereof
|
US12030888B2
(en)
|
2021-02-24 |
2024-07-09 |
Massachusetts Institute Of Technology |
Himastatin derivatives, and processes of preparation thereof, and uses thereof
|
AU2022230384A1
(en)
|
2021-03-01 |
2023-09-07 |
Xilio Development, Inc. |
Combination of masked ctla4 and pd1/pdl1 antibodies for treating cancer
|
WO2022187270A1
(en)
|
2021-03-01 |
2022-09-09 |
Xilio Development, Inc. |
Combination of ctla4 and pd1/pdl1 antibodies for treating cancer
|
KR20230158004A
(ko)
|
2021-03-08 |
2023-11-17 |
진콴텀 헬스케어 (쑤저우) 씨오., 엘티디. |
항체 면역 작용제 접합체 및 이의 적용
|
KR20230156079A
(ko)
|
2021-03-09 |
2023-11-13 |
젠코어 인코포레이티드 |
Cd3과 cldn6에 결합하는 이종이량체 항체
|
WO2022192586A1
(en)
|
2021-03-10 |
2022-09-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and gpc3
|
CA3212822A1
(en)
|
2021-03-11 |
2022-09-15 |
Ajinomoto Co., Inc. |
Compound or salt thereof, and antibody obtained by using the same
|
EP4310096A1
(en)
|
2021-03-16 |
2024-01-24 |
Ajinomoto Co., Inc. |
Complex or salt thereof, and method for manufacturing same
|
EP4308171A1
(en)
|
2021-03-18 |
2024-01-24 |
Seagen Inc. |
Selective drug release from internalized conjugates of biologically active compounds
|
KR20230158005A
(ko)
|
2021-03-18 |
2023-11-17 |
씨젠 인크. |
생물학적 활성 화합물의 내재화된 접합체로부터의 선택적 약물 방출
|
KR20240012352A
(ko)
|
2021-03-23 |
2024-01-29 |
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) |
T 세포 림프종의 진단 및 치료 방법
|
EP4314047A1
(en)
|
2021-03-30 |
2024-02-07 |
Bayer Aktiengesellschaft |
Anti-sema3a antibodies and uses thereof
|
EP4320153A1
(en)
|
2021-04-09 |
2024-02-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the treatment of anaplastic large cell lymphoma
|
AU2022253902A1
(en)
|
2021-04-10 |
2023-11-02 |
Profoundbio Us Co. |
Folr1 binding agents, conjugates thereof and methods of using the same
|
WO2022218331A1
(en)
|
2021-04-14 |
2022-10-20 |
Genequantum Healthcare (Suzhou) Co., Ltd. |
Linkers, conjugates and applications thereof
|
AR125344A1
(es)
|
2021-04-15 |
2023-07-05 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-c1s
|
TW202308699A
(zh)
|
2021-04-23 |
2023-03-01 |
美商普方生物製藥美國公司 |
Cd70結合劑、其結合物及其使用方法
|
CN116917324A
(zh)
|
2021-04-26 |
2023-10-20 |
江苏恒瑞医药股份有限公司 |
抗Nectin-4抗体和抗Nectin-4抗体-药物偶联物及其医药用途
|
CN117321078A
(zh)
|
2021-04-30 |
2023-12-29 |
豪夫迈·罗氏有限公司 |
针对用抗cd20/抗cd3双特异性抗体和抗cd79b抗体药物缀合物进行组合治疗的给药
|
CN117396231A
(zh)
|
2021-04-30 |
2024-01-12 |
新基公司 |
使用抗BCMA抗体药物缀合物(ADC)与γ分泌酶抑制剂(GSI)的组合的组合疗法
|
MX2023012699A
(es)
|
2021-04-30 |
2023-11-21 |
Hoffmann La Roche |
Dosificacion para el tratamiento con anticuerpo biespecifico anti-cd20/anti-cd3.
|
CA3218170A1
(en)
|
2021-05-12 |
2022-11-17 |
Jamie Harue HIRATA |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
CN117321219A
(zh)
|
2021-05-19 |
2023-12-29 |
中外制药株式会社 |
预测分子的体内药代动力学的方法
|
BR112023023525A2
(pt)
*
|
2021-05-19 |
2024-01-30 |
Biohaven Therapeutics Ltd |
Conjugados de anticorpo-fármaco usando tecnologia mates para distribuir agentes citotóxicos
|
JP2024521667A
(ja)
|
2021-05-26 |
2024-06-04 |
オックスフォード バイオセラピューティックス リミテッド |
抗-cd205抗体及び免疫チェックポイント・インヒビターを含む組み合わせ医薬
|
WO2022248870A1
(en)
|
2021-05-28 |
2022-12-01 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapies for treating cancer
|
CN117480184A
(zh)
|
2021-06-04 |
2024-01-30 |
中外制药株式会社 |
抗ddr2抗体及其用途
|
WO2022271987A1
(en)
|
2021-06-23 |
2022-12-29 |
TeneoFour, Inc. |
Anti-cd38 antibodies and epitopes of same
|
KR102690141B1
(ko)
|
2021-06-25 |
2024-07-30 |
추가이 세이야쿠 가부시키가이샤 |
항ctla-4 항체
|
MX2023014453A
(es)
|
2021-06-25 |
2024-01-31 |
Chugai Pharmaceutical Co Ltd |
Uso de anticuerpos anti-antigeno 4 del linfocito t citotoxico (anti-ctla-4).
|
TW202317190A
(zh)
|
2021-06-29 |
2023-05-01 |
美商思進公司 |
以非岩藻糖基化抗cd70抗體及cd47拮抗劑之組合治療癌症之方法
|
TW202320857A
(zh)
|
2021-07-06 |
2023-06-01 |
美商普方生物製藥美國公司 |
連接子、藥物連接子及其結合物及其使用方法
|
JP2024526764A
(ja)
|
2021-07-13 |
2024-07-19 |
トゥルーバインディング,インコーポレイテッド |
タンパク質凝集を防止する方法
|
WO2023288236A1
(en)
|
2021-07-14 |
2023-01-19 |
Seagen Inc. |
Antibody masking domains
|
US11806405B1
(en)
|
2021-07-19 |
2023-11-07 |
Zeno Management, Inc. |
Immunoconjugates and methods
|
CN113710277B
(zh)
*
|
2021-07-19 |
2023-09-01 |
烟台迈百瑞国际生物医药股份有限公司 |
一种负载双毒素的抗体药物偶联物及其应用
|
AU2022314086A1
(en)
|
2021-07-21 |
2024-02-22 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Pharmaceutical composition containing anti-trop2 antibody drug conjugate and use thereof
|
EP4374879A1
(en)
|
2021-07-22 |
2024-05-29 |
Shanghai Senhui Medicine Co., Ltd. |
Drug conjugate of eribulin derivative
|
CA3227515A1
(en)
|
2021-08-03 |
2023-02-09 |
Glaxosmithkline Intellectual Property Development Limited |
Biopharmaceutical compositions and stable isotope labeling peptide mapping method
|
EP4380978A1
(en)
|
2021-08-07 |
2024-06-12 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
KR20240051162A
(ko)
|
2021-09-02 |
2024-04-19 |
도이체스크레브스포르슝스젠트룸스티프퉁데스외펜트리헨레크츠 |
부작용이 감소된 항-cecam6 항체
|
CN118119409A
(zh)
|
2021-09-03 |
2024-05-31 |
东丽株式会社 |
癌的治疗和/或预防用药物组合物
|
CA3230774A1
(en)
|
2021-09-06 |
2023-03-09 |
Veraxa Biotech Gmbh |
Novel aminoacyl-trna synthetase variants for genetic code expansion in eukaryotes
|
EP4401842A1
(en)
|
2021-09-16 |
2024-07-24 |
Aboleris Pharma |
Anti-human cd45rc binding domains and uses thereof
|
CA3231330A1
(en)
|
2021-09-16 |
2023-03-23 |
Avidity Biosciences, Inc. |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
EP4405387A1
(en)
|
2021-09-24 |
2024-07-31 |
Seagen Inc. |
Improved antibody masking domains
|
CA3234692A1
(en)
|
2021-09-30 |
2023-04-06 |
Ajinomoto Co., Inc. |
Conjugate of antibody and functional substance or salt thereof, and antibody derivative and compound used in production of the same or salts thereof
|
WO2023056069A1
(en)
|
2021-09-30 |
2023-04-06 |
Angiex, Inc. |
Degrader-antibody conjugates and methods of using same
|
WO2023056403A1
(en)
|
2021-09-30 |
2023-04-06 |
Genentech, Inc. |
Methods for treatment of hematologic cancers using anti-tigit antibodies, anti-cd38 antibodies, and pd-1 axis binding antagonists
|
CA3234689A1
(en)
|
2021-09-30 |
2023-04-06 |
Ajinomoto Co., Inc. |
Regioselective conjugate of antibody and functional substance or salt thereof, and antibody derivative and compound used in production of the same or salts thereof
|
KR20240112819A
(ko)
|
2021-09-30 |
2024-07-19 |
지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 |
피롤로벤조디아제핀 유도체 및 이의 접합체, 이의 제조 방법 및 이의 응용
|
WO2023057893A1
(en)
|
2021-10-05 |
2023-04-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapies for treating cancer
|
TW202333781A
(zh)
|
2021-10-08 |
2023-09-01 |
日商中外製藥股份有限公司 |
抗hla-dq2﹒5抗體製劑
|
KR20240110584A
(ko)
*
|
2021-11-03 |
2024-07-15 |
애드센트릭스 테라퓨틱스 잉크. |
신규한 오리스타틴 유사체 및 이의 면역접합체
|
AU2022386505A1
(en)
|
2021-11-15 |
2024-05-23 |
Systimmune, Inc. |
Bispecific antibody-camptothecin drug conjugate and pharmaceutical use thereof
|
WO2023089314A1
(en)
|
2021-11-18 |
2023-05-25 |
Oxford Biotherapeutics Limited |
Pharmaceutical combinations
|
CA3238167A1
(en)
|
2021-11-19 |
2023-05-25 |
Maria Leia Smith |
Gpc3 binding agents, conjugates thereof and methods of using the same
|
AU2022395626A1
(en)
|
2021-11-25 |
2024-05-30 |
Veraxa Biotech Gmbh |
Improved antibody-payload conjugates (apcs) prepared by site-specific conjugation utilizing genetic code expansion
|
EP4186529A1
(en)
|
2021-11-25 |
2023-05-31 |
Veraxa Biotech GmbH |
Improved antibody-payload conjugates (apcs) prepared by site-specific conjugation utilizing genetic code expansion
|
CN116212044A
(zh)
|
2021-12-03 |
2023-06-06 |
成都百利多特生物药业有限责任公司 |
抗人Trop2抗体-喜树碱类药物偶联物及其医药用途
|
CA3239713A1
(en)
|
2021-12-08 |
2023-06-15 |
Edward A. LEMKE |
Hydrophilic tetrazine-functionalized payloads for preparation of targeting conjugates
|
WO2023110937A1
(en)
|
2021-12-14 |
2023-06-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Depletion of nk cells for the treatment of adverse post-ischemic cardiac remodeling
|
AU2022411573A1
(en)
|
2021-12-17 |
2024-06-27 |
Shanghai Henlius Biologics Co., Ltd. |
Anti-ox40 antibodies and methods of use
|
CA3242384A1
(en)
|
2021-12-17 |
2023-06-22 |
3B Pharmaceuticals Gmbh |
Carbonic anhydrase ix ligands
|
AU2022408865A1
(en)
|
2021-12-17 |
2024-07-04 |
Shanghai Henlius Biologics Co., Ltd. |
Anti-ox40 antibodies, multispecific antibodies and methods of use
|
CA3240378A1
(en)
|
2021-12-23 |
2023-06-29 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Anti-dll3 antibody and pharmaceutical use thereof, and antibody-drug conjugate containing anti-dll3 antibody
|
CA3241529A1
(en)
|
2021-12-23 |
2023-06-29 |
Mirecule, Inc. |
Compositions for delivery of polynucleotides
|
WO2023125619A1
(zh)
|
2021-12-28 |
2023-07-06 |
江苏恒瑞医药股份有限公司 |
抗ror1抗体和抗ror1抗体药物偶联物及其医药用途
|
AU2023206045A1
(en)
|
2022-01-07 |
2024-08-22 |
Johnson & Johnson Enterprise Innovation Inc. |
Materials and methods of il-1beta binding proteins
|
AR128331A1
(es)
|
2022-01-26 |
2024-04-17 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpos y métodos de estos
|
TW202334207A
(zh)
|
2022-01-26 |
2023-09-01 |
大陸商上海邁晉生物醫藥科技有限公司 |
一種包含抗cd79b抗體藥物偶聯物的醫藥組成物及其用途
|
WO2023147488A1
(en)
|
2022-01-28 |
2023-08-03 |
Iovance Biotherapeutics, Inc. |
Cytokine associated tumor infiltrating lymphocytes compositions and methods
|
TW202340252A
(zh)
|
2022-01-29 |
2023-10-16 |
大陸商上海盛迪醫藥有限公司 |
糖皮質激素的藥物偶聯物
|
WO2023144303A1
(en)
|
2022-01-31 |
2023-08-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd38 as a biomarker and biotarget in t-cell lymphomas
|
WO2023158305A1
(en)
|
2022-02-15 |
2023-08-24 |
Tagworks Pharmaceuticals B.V. |
Masked il12 protein
|
US11590169B1
(en)
|
2022-03-02 |
2023-02-28 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-CD123 immunotherapy
|
US20230338424A1
(en)
|
2022-03-02 |
2023-10-26 |
Lentigen Technology, Inc. |
Compositions and Methods for Treating Cancer with Anti-CD123 Immunotherapy
|
WO2023169896A1
(en)
|
2022-03-09 |
2023-09-14 |
Astrazeneca Ab |
BINDING MOLECULES AGAINST FRα
|
AU2023229967A1
(en)
|
2022-03-11 |
2024-08-08 |
Astrazeneca Ab |
A SCORING METHOD FOR AN ANTI-FRα ANTIBODY-DRUG CONJUGATE THERAPY
|
AU2023238766A1
(en)
|
2022-03-23 |
2024-07-25 |
F. Hoffmann-La Roche Ag |
Combination treatment of an anti-cd20/anti-cd3 bispecific antibody and chemotherapy
|
AU2022447933A1
(en)
|
2022-03-25 |
2023-11-09 |
Baili-Bio (Chengdu) Pharmaceutical Co, Ltd. |
Dna toxic dimer compound and conjugate thereof
|
WO2023191816A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
US12071621B2
(en)
|
2022-04-05 |
2024-08-27 |
Avidity Biosciences, Inc. |
Anti-transferrin receptor antibody-PMO conjugates for inducing DMD exon 44 skipping
|
WO2023198648A1
(en)
|
2022-04-11 |
2023-10-19 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the diagnosis and treatment of t-cell malignancies
|
WO2023201299A1
(en)
|
2022-04-13 |
2023-10-19 |
Genentech, Inc. |
Pharmaceutical compositions of therapeutic proteins and methods of use
|
TW202404637A
(zh)
|
2022-04-13 |
2024-02-01 |
瑞士商赫孚孟拉羅股份公司 |
抗cd20/抗cd3雙特異性抗體之醫藥組成物及使用方法
|
WO2023198874A1
(en)
|
2022-04-15 |
2023-10-19 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the diagnosis and treatment of t cell-lymphomas
|
US20230346862A1
(en)
|
2022-05-02 |
2023-11-02 |
Athanor Biosciences, Inc. |
Cancer eradicating - bio-nanoparticles (ce-bnp)
|
WO2023215737A1
(en)
|
2022-05-03 |
2023-11-09 |
Genentech, Inc. |
Anti-ly6e antibodies, immunoconjugates, and uses thereof
|
TW202408583A
(zh)
|
2022-05-06 |
2024-03-01 |
丹麥商珍美寶股份有限公司 |
使用抗組織因子抗體-藥物共軛體以治療癌症之方法
|
WO2023219613A1
(en)
|
2022-05-11 |
2023-11-16 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2023227660A1
(en)
|
2022-05-25 |
2023-11-30 |
Innate Pharma |
Nectin-4 binding agents
|
WO2023240058A2
(en)
|
2022-06-07 |
2023-12-14 |
Genentech, Inc. |
Prognostic and therapeutic methods for cancer
|
WO2024001669A1
(zh)
|
2022-06-27 |
2024-01-04 |
昱言科技(北京)有限公司 |
靶向itga2的抗体和包含此抗体的抗体药物缀合物
|
WO2024006542A1
(en)
|
2022-06-30 |
2024-01-04 |
Sutro Biopharma, Inc. |
Anti-ror1 antibodies and antibody conjugates, compositions comprising anti-ror1 antibodies or antibody conjugates, and methods of making and using anti-ror1 antibodies and antibody conjugates
|
WO2024003310A1
(en)
|
2022-06-30 |
2024-01-04 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the diagnosis and treatment of acute lymphoblastic leukemia
|
TW202417042A
(zh)
|
2022-07-13 |
2024-05-01 |
美商建南德克公司 |
用抗fcrh5/抗cd3雙特異性抗體進行治療之給藥
|
WO2024013723A1
(en)
|
2022-07-15 |
2024-01-18 |
Pheon Therapeutics Ltd |
Antibody drug conjugates that bind cdcp1 and uses thereof
|
WO2024020432A1
(en)
|
2022-07-19 |
2024-01-25 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024018046A1
(en)
|
2022-07-22 |
2024-01-25 |
Institut National de la Santé et de la Recherche Médicale |
Garp as a biomarker and biotarget in t-cell malignancies
|
TW202417504A
(zh)
|
2022-07-22 |
2024-05-01 |
美商建南德克公司 |
抗steap1抗原結合分子及其用途
|
TW202412762A
(zh)
*
|
2022-07-27 |
2024-04-01 |
香港商祐方有限公司 |
奧瑞他汀衍生物及其結合物
|
WO2024026107A2
(en)
|
2022-07-28 |
2024-02-01 |
Lentigen Technology, Inc. |
Chimeric antigen receptor therapies for treating solid tumors
|
WO2024026474A1
(en)
|
2022-07-29 |
2024-02-01 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for transferrin receptor (tfr)-mediated delivery to the brain and muscle
|
WO2024023283A1
(en)
|
2022-07-29 |
2024-02-01 |
Institut National de la Santé et de la Recherche Médicale |
Lrrc33 as a biomarker and biotarget in cutaneous t-cell lymphomas
|
EP4321522A1
(en)
|
2022-08-12 |
2024-02-14 |
Seagen Inc. |
Cytotoxic compounds and conjugates thereof
|
US20240075142A1
(en)
|
2022-08-26 |
2024-03-07 |
Lentigen Technology, Inc. |
Compositions and Methods for Treating Cancer with Fully Human Anti-CD20/CD19 Immunotherapy
|
WO2024049949A1
(en)
|
2022-09-01 |
2024-03-07 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
WO2024064714A2
(en)
|
2022-09-21 |
2024-03-28 |
Seagen Inc. |
Antibodies that bind cd228
|
WO2024079192A1
(en)
|
2022-10-12 |
2024-04-18 |
Institut National de la Santé et de la Recherche Médicale |
Cd81 as a biomarker and biotarget in t-cell malignancies
|
WO2024080872A1
(en)
|
2022-10-12 |
2024-04-18 |
Tagworks Pharmaceuticals B.V. |
Strained bicyclononenes
|
WO2024091991A1
(en)
|
2022-10-25 |
2024-05-02 |
Genentech, Inc. |
Therapeutic and diagnostic methods for multiple myeloma
|
WO2024097816A1
(en)
|
2022-11-03 |
2024-05-10 |
Seagen Inc. |
Anti-avb6 antibodies and antibody-drug conjugates and their use in the treatment of cancer
|
WO2024102948A1
(en)
|
2022-11-11 |
2024-05-16 |
Celgene Corporation |
Fc receptor-homolog 5 (fcrh5) specific binding molecules and bispecific t-cell engaging antibodies including same and related methods
|
WO2024107765A2
(en)
|
2022-11-14 |
2024-05-23 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for fibroblast growth factor receptor 3-mediated delivery to astrocytes
|
WO2024124134A1
(en)
*
|
2022-12-09 |
2024-06-13 |
Seagen Inc. |
Process for making auristatin containing compounds
|
WO2024121632A1
(en)
|
2022-12-09 |
2024-06-13 |
Crispr Therapeutics Ag |
Use of anti-cd117 antibody drug conjugate (adc)
|
US20240226298A1
(en)
|
2022-12-13 |
2024-07-11 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for baff-r and cd19 and methods and uses thereof
|
WO2024129756A1
(en)
|
2022-12-13 |
2024-06-20 |
Seagen Inc. |
Site-specific engineered cysteine antibody drug conjugates
|
WO2024129628A1
(en)
|
2022-12-14 |
2024-06-20 |
Merck Sharp & Dohme Llc |
Auristatin linker-payloads, pharmaceutical compositions, and uses thereof
|
US20240269308A1
(en)
*
|
2022-12-21 |
2024-08-15 |
Regeneron Pharmaceuticals, Inc. |
Prodrugs of topoisomerase i inhibitor for adc conjugations and methods of use thereof
|
GB202300668D0
(en)
|
2023-01-17 |
2023-03-01 |
Univ Bradford |
Cancer treating compounds
|
WO2024153789A1
(en)
|
2023-01-20 |
2024-07-25 |
Basf Se |
Stabilized biopolymer composition, their manufacture and use
|
WO2024165484A1
(en)
|
2023-02-06 |
2024-08-15 |
Institut National de la Santé et de la Recherche Médicale |
Enrichment of genetically modified hematopoietic stem cells through multiplex base editing
|
WO2024165045A1
(en)
|
2023-02-09 |
2024-08-15 |
Beigene, Ltd. |
Self-stabilizing linker conjugates
|
WO2024173384A1
(en)
|
2023-02-14 |
2024-08-22 |
Bolt Biotherapeutics, Inc. |
Aza-benzazepine immunoconjugates, and uses thereof
|
WO2024170543A1
(en)
|
2023-02-14 |
2024-08-22 |
Institut National de la Santé et de la Recherche Médicale |
Anti-cd44 antibodies and uses thereof
|
WO2024170660A1
(en)
|
2023-02-16 |
2024-08-22 |
Astrazeneca Ab |
Combination therapies for treatment of cancer with therapeutic binding molecules
|
CN116284202B
(zh)
*
|
2023-03-28 |
2024-07-02 |
华侨大学 |
白桦脂酸的PROTACs化合物及其制备方法和应用
|