HK1079118A1 - Stable injectable diclofenac compositions - Google Patents
Stable injectable diclofenac compositionsInfo
- Publication number
- HK1079118A1 HK1079118A1 HK06100808A HK06100808A HK1079118A1 HK 1079118 A1 HK1079118 A1 HK 1079118A1 HK 06100808 A HK06100808 A HK 06100808A HK 06100808 A HK06100808 A HK 06100808A HK 1079118 A1 HK1079118 A1 HK 1079118A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- diclofenac
- cyclodextrin
- salt
- stable injectable
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55135104P | 2004-03-10 | 2004-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1079118A1 true HK1079118A1 (en) | 2006-03-31 |
Family
ID=34826259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK06100808A HK1079118A1 (en) | 2004-03-10 | 2006-01-18 | Stable injectable diclofenac compositions |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20050238674A1 (de) |
| EP (2) | EP1767219B1 (de) |
| JP (1) | JP2007528384A (de) |
| KR (1) | KR20070028331A (de) |
| AT (2) | ATE454905T1 (de) |
| AU (1) | AU2004317520B2 (de) |
| BR (1) | BRPI0418474A (de) |
| CA (1) | CA2555429C (de) |
| CY (1) | CY1106824T1 (de) |
| DE (2) | DE602004025151D1 (de) |
| DK (2) | DK1767219T3 (de) |
| ES (2) | ES2287658T3 (de) |
| HK (1) | HK1079118A1 (de) |
| IL (1) | IL177529A (de) |
| MX (1) | MXPA06010336A (de) |
| PL (2) | PL1767219T3 (de) |
| PT (2) | PT1767219E (de) |
| SI (2) | SI1574221T1 (de) |
| WO (2) | WO2005092387A1 (de) |
| ZA (2) | ZA200607631B (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2392097T3 (es) | 2005-02-01 | 2012-12-04 | Troikaa Pharmaceuticals Ltd. | Preparaciones inyectables de diclofenaco y sus sales farmacéuticamente aceptables |
| US20060205080A1 (en) * | 2005-03-01 | 2006-09-14 | David Frey | Formulations for therapeutic viruses having enhanced storage stability |
| MX2008012495A (es) * | 2006-03-28 | 2009-01-07 | Javelin Pharmaceuticals Inc | Formulaciones de dosis baja de diclofenaco y beta-ciclodextrina. |
| JP2009531451A (ja) * | 2006-03-28 | 2009-09-03 | ジャヴェリン ファーマシューティカルズ インコーポレイテッド | 低投与量の非ステロイド系抗炎症薬及びβ−シクロデキストリンの配合物 |
| AU2012209035B9 (en) * | 2006-03-28 | 2014-05-22 | Javelin Pharmaceuticals, Inc. | Formulations of low dose diclofenac and beta-cyclodextrin |
| CL2007003877A1 (es) | 2007-12-28 | 2008-06-27 | Univ De Concepcion Lab Androma | Composicion farmaceutica que comprende un complejo de inclusion formado por disulfiram y una ciclodextrina; y su uso para el tratamiento de la dependencia de alcohol y cocaina. |
| WO2010014306A1 (en) * | 2008-07-28 | 2010-02-04 | Tyco Healthcare Group Lp | Antimicrobial and anticoagulant compositions and methods |
| JP2012520342A (ja) | 2009-03-16 | 2012-09-06 | ジェンメディカ・セラピューティックス・ソシエダッド・リミターダ | 代謝障害を処置するのに有用な抗炎症剤および抗酸化剤のコンジュゲート |
| US8466197B2 (en) | 2010-12-14 | 2013-06-18 | Genmedica Therapeutics Sl | Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders |
| GB201021267D0 (en) * | 2010-12-15 | 2011-01-26 | Reckitt Benckiser Healthcare Int Ltd | Novel pharmaceutical formulation |
| MY166036A (en) * | 2011-07-20 | 2018-05-21 | Hospira Inc | Methods of treating pain |
| EP2741742A1 (de) * | 2011-08-11 | 2014-06-18 | Cross SA | Pharmazeutische zusammensetzung mit einem wirkstoff mit mindestens einer toxophoren funktion und n-acetyl-l-cystein |
| KR101260636B1 (ko) | 2012-11-29 | 2013-05-13 | 씨제이제일제당 (주) | 안정화된 페메트렉시드 제제 |
| US20140187635A1 (en) | 2012-12-28 | 2014-07-03 | Themis Medicare Limited | Diclofenac compositions |
| US20140275261A1 (en) | 2013-03-15 | 2014-09-18 | Dr. Reddy's Laboratories, Inc. | Diclofenac parenteral compositions |
| KR101485243B1 (ko) | 2013-05-08 | 2015-01-21 | 씨제이헬스케어 주식회사 | 안정화된 페메트렉시드 제제 |
| US11110073B2 (en) | 2017-03-24 | 2021-09-07 | Cadila Healthcare Limited | Storage stable aqueous injectable solution comprising diclofenac |
| EP3664800B1 (de) * | 2017-08-09 | 2024-05-08 | Dechra Veterinary Products, LLC | Therapeutische formulierungen enthaltend cox-2-inhibitor und verwendungen davon |
| US20220280463A1 (en) | 2019-09-09 | 2022-09-08 | Ftf Pharma Private Limited | Pharmaceutical formulations comprising diclofenac |
| US11707443B2 (en) | 2019-09-26 | 2023-07-25 | Rk Pharma Inc. | Storage stable aqueous parenteral solutions comprising diclofenac |
| CN110872942B (zh) * | 2019-10-24 | 2021-09-28 | 中国石油化工股份有限公司 | 油藏注采耦合方式下不同作用力对采收率贡献的研究方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3446873A1 (de) * | 1984-12-21 | 1986-07-10 | Merckle Gmbh | Fluessige diclofenac-zubereitungen |
| US5690954A (en) * | 1987-05-22 | 1997-11-25 | Danbiosyst Uk Limited | Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material |
| US5389681A (en) * | 1992-10-22 | 1995-02-14 | Ciba-Geigy Corporation | Parenteral solutions for diclofenac salts |
| IL111184A (en) * | 1993-10-08 | 2000-08-13 | Farmarc Nederland B V Of Cito | Crystalline inclusion complex of diclofenac with unsubstituted beta-cyclodextrin |
| ZA949182B (en) * | 1993-12-02 | 1995-07-26 | South African Druggists Ltd | Pharmaceutical composition |
| EP0785780A1 (de) * | 1994-10-10 | 1997-07-30 | Novartis AG | Ophthalmische und aurale zusammensetzungen enthaltende diclofenac-kalium |
| US5821237A (en) * | 1995-06-07 | 1998-10-13 | The Procter & Gamble Company | Compositions for visually improving skin |
| WO1996041646A2 (en) * | 1995-06-13 | 1996-12-27 | Dyer, Alison, Margaret | Pharmaceutical compositions containing lornoxicam and cyclodextrin |
| TW434023B (en) * | 1995-09-18 | 2001-05-16 | Novartis Ag | Preserved ophthalmic composition |
| FR2751875B1 (fr) * | 1996-08-05 | 1998-12-24 | Scr Newpharm | Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation |
| AU4979700A (en) * | 1999-05-03 | 2000-11-17 | Battelle Memorial Institute | Compositions for aerosolization and inhalation |
| EP1219304B1 (de) * | 2000-12-28 | 2004-10-20 | Fresenius Kabi Austria GmbH | Stabile Infusionslösung von Diclofenac-Salzen, deren Herstellung und Verwendung |
| WO2003063824A2 (en) * | 2002-02-01 | 2003-08-07 | Shimoda Biotech (Pty) Ltd | Pharmaceutical composition |
| AU2003213210A1 (en) * | 2002-02-22 | 2003-09-09 | Pharmacia Corporation | Ophthalmic formulation with gum system |
-
2004
- 2004-11-30 MX MXPA06010336A patent/MXPA06010336A/es active IP Right Grant
- 2004-11-30 DE DE602004025151T patent/DE602004025151D1/de active Active
- 2004-11-30 PL PL07075004T patent/PL1767219T3/pl unknown
- 2004-11-30 ZA ZA200607631A patent/ZA200607631B/xx unknown
- 2004-11-30 JP JP2007502421A patent/JP2007528384A/ja active Pending
- 2004-11-30 US US10/999,155 patent/US20050238674A1/en not_active Abandoned
- 2004-11-30 CA CA2555429A patent/CA2555429C/en not_active Expired - Fee Related
- 2004-11-30 AT AT07075004T patent/ATE454905T1/de active
- 2004-11-30 DK DK07075004.7T patent/DK1767219T3/da active
- 2004-11-30 BR BRPI0418474-2A patent/BRPI0418474A/pt not_active Application Discontinuation
- 2004-11-30 WO PCT/IB2004/003918 patent/WO2005092387A1/en active Application Filing
- 2004-11-30 KR KR1020067018393A patent/KR20070028331A/ko not_active Application Discontinuation
- 2004-11-30 DE DE602004006952T patent/DE602004006952T2/de active Active
- 2004-11-30 AU AU2004317520A patent/AU2004317520B2/en not_active Ceased
- 2004-11-30 DK DK04257437T patent/DK1574221T3/da active
- 2004-11-30 EP EP07075004A patent/EP1767219B1/de not_active Not-in-force
- 2004-11-30 SI SI200430347T patent/SI1574221T1/sl unknown
- 2004-11-30 EP EP04257437A patent/EP1574221B1/de active Active
- 2004-11-30 AT AT04257437T patent/ATE364402T1/de active
- 2004-11-30 ES ES04257437T patent/ES2287658T3/es active Active
- 2004-11-30 SI SI200431321T patent/SI1767219T1/sl unknown
- 2004-11-30 PT PT07075004T patent/PT1767219E/pt unknown
- 2004-11-30 ES ES07075004T patent/ES2336034T3/es active Active
- 2004-11-30 PL PL04257437T patent/PL1574221T3/pl unknown
- 2004-11-30 PT PT04257437T patent/PT1574221E/pt unknown
-
2005
- 2005-03-04 WO PCT/US2005/007354 patent/WO2005086763A2/en active Application Filing
-
2006
- 2006-01-18 HK HK06100808A patent/HK1079118A1/xx not_active IP Right Cessation
- 2006-08-16 IL IL177529A patent/IL177529A/en not_active IP Right Cessation
-
2007
- 2007-08-23 CY CY20071101108T patent/CY1106824T1/el unknown
-
2008
- 2008-07-04 ZA ZA200805860A patent/ZA200805860B/en unknown
-
2011
- 2011-06-03 US US13/153,283 patent/US20120142779A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20181130 |