HK1073295A1 - Acetyl l-carnitine acid fumarate and process for preparing the same - Google Patents

Acetyl l-carnitine acid fumarate and process for preparing the same

Info

Publication number
HK1073295A1
HK1073295A1 HK05105831A HK05105831A HK1073295A1 HK 1073295 A1 HK1073295 A1 HK 1073295A1 HK 05105831 A HK05105831 A HK 05105831A HK 05105831 A HK05105831 A HK 05105831A HK 1073295 A1 HK1073295 A1 HK 1073295A1
Authority
HK
Hong Kong
Prior art keywords
acetyl
preparing
same
acid fumarate
carnitine acid
Prior art date
Application number
HK05105831A
Other languages
English (en)
Inventor
Aldo Fassi
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of HK1073295A1 publication Critical patent/HK1073295A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/02—Preparation of carboxylic acid esters by interreacting ester groups, i.e. transesterification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK05105831A 2001-12-12 2005-07-11 Acetyl l-carnitine acid fumarate and process for preparing the same HK1073295A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001RM000729A ITRM20010729A1 (it) 2001-12-12 2001-12-12 Sale di acetil l-carnitina con un acido organico dicarbossilico e procedimento per la sua preparazione.
PCT/IT2002/000743 WO2003053911A1 (fr) 2001-12-12 2002-11-25 Sel d'acetyl l-carnitine associe a un acide organique dicarboxilique et procede de preparation correspondant

Publications (1)

Publication Number Publication Date
HK1073295A1 true HK1073295A1 (en) 2005-09-30

Family

ID=11455916

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05105831A HK1073295A1 (en) 2001-12-12 2005-07-11 Acetyl l-carnitine acid fumarate and process for preparing the same

Country Status (19)

Country Link
US (1) US6673837B2 (fr)
EP (1) EP1453791B1 (fr)
JP (1) JP4902940B2 (fr)
KR (1) KR100860386B1 (fr)
CN (1) CN1250521C (fr)
AT (1) ATE457300T1 (fr)
AU (1) AU2002358989A1 (fr)
CA (1) CA2468234C (fr)
CY (1) CY1110684T1 (fr)
DE (1) DE60235318D1 (fr)
DK (1) DK1453791T3 (fr)
ES (1) ES2339432T3 (fr)
HK (1) HK1073295A1 (fr)
HU (1) HU230034B1 (fr)
IT (1) ITRM20010729A1 (fr)
PL (1) PL207877B1 (fr)
PT (1) PT1453791E (fr)
SI (1) SI1453791T1 (fr)
WO (1) WO2003053911A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8173618B2 (en) * 2003-07-25 2012-05-08 University Of Massachusetts Formulations for reducing neuronal degeneration
CN101209975B (zh) * 2006-12-29 2010-12-01 沈阳科硕营养科技有限公司 左旋肉碱富马酸钙及其制备方法与用途
US8597640B2 (en) * 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging
JP2012092036A (ja) * 2010-10-26 2012-05-17 Mitsubishi Rayon Co Ltd カルニチンの塩の製造方法
EP2750650B1 (fr) * 2011-08-31 2021-06-16 The Procter & Gamble Company Élément de fixation comprenant une couche de renforcement liée
JP5933383B2 (ja) * 2012-07-26 2016-06-08 ロート製薬株式会社 内服用固形製剤の吸湿性・流動性の改善方法、吸湿性・流動性が改善されてなる内服用固形製剤、及び該内服用固形製剤の製造法
JP6100939B2 (ja) * 2016-02-26 2017-03-22 ロート製薬株式会社 内服用固形製剤の吸湿性・流動性の改善方法、吸湿性・流動性が改善されてなる内服用固形製剤、及び該内服用固形製剤の製造法
JP6964876B2 (ja) * 2017-11-27 2021-11-10 株式会社古川リサーチオフィス オロット酸−カルニチン混合体粉体又はフマル酸−カルニチン混合体粉体の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3463261D1 (en) * 1983-12-28 1987-05-27 Sigma Tau Ind Farmaceuti Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same

Also Published As

Publication number Publication date
CN1250521C (zh) 2006-04-12
DE60235318D1 (de) 2010-03-25
EP1453791B1 (fr) 2010-02-10
CA2468234C (fr) 2010-02-23
EP1453791A1 (fr) 2004-09-08
US20030119904A1 (en) 2003-06-26
AU2002358989A1 (en) 2003-07-09
CA2468234A1 (fr) 2003-07-03
PL371130A1 (en) 2005-06-13
DK1453791T3 (da) 2010-05-25
ES2339432T3 (es) 2010-05-20
CY1110684T1 (el) 2015-06-10
ITRM20010729A1 (it) 2003-06-12
JP2005513122A (ja) 2005-05-12
US6673837B2 (en) 2004-01-06
CN1602294A (zh) 2005-03-30
ATE457300T1 (de) 2010-02-15
HUP0402545A2 (hu) 2005-04-28
JP4902940B2 (ja) 2012-03-21
SI1453791T1 (sl) 2010-11-30
PT1453791E (pt) 2010-04-14
HUP0402545A3 (en) 2012-09-28
HU230034B1 (hu) 2015-05-28
KR20040064721A (ko) 2004-07-19
PL207877B1 (pl) 2011-02-28
WO2003053911A1 (fr) 2003-07-03
KR100860386B1 (ko) 2008-09-26

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20151125