HK1022838A1 - Phenylethylamine derivatives - Google Patents

Phenylethylamine derivatives

Info

Publication number
HK1022838A1
HK1022838A1 HK00101884A HK00101884A HK1022838A1 HK 1022838 A1 HK1022838 A1 HK 1022838A1 HK 00101884 A HK00101884 A HK 00101884A HK 00101884 A HK00101884 A HK 00101884A HK 1022838 A1 HK1022838 A1 HK 1022838A1
Authority
HK
Hong Kong
Prior art keywords
dementia
alkyl
hydrogen
compounds
directed
Prior art date
Application number
HK00101884A
Other languages
English (en)
Inventor
Michael Chorev
Tamar Goren
Yacov Herzig
Jeffrey Sterling
Marta Weinstock-Rosin
Moussa B H Youdim
Original Assignee
Teva Pharma
Yissum Res Dev Co
Technion Res & Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL11985296A external-priority patent/IL119852A0/xx
Priority claimed from IL12050997A external-priority patent/IL120509A0/xx
Application filed by Teva Pharma, Yissum Res Dev Co, Technion Res & Dev Foundation filed Critical Teva Pharma
Publication of HK1022838A1 publication Critical patent/HK1022838A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/56—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK00101884A 1996-12-18 2000-03-28 Phenylethylamine derivatives HK1022838A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL11985296A IL119852A0 (en) 1996-12-18 1996-12-18 Phenylethylamine derivatives
IL12050997A IL120509A0 (en) 1997-03-24 1997-03-24 Phenylethylamine derivatives
PCT/US1997/023897 WO1998026775A1 (en) 1996-12-18 1997-12-18 Phenylethylamine derivatives

Publications (1)

Publication Number Publication Date
HK1022838A1 true HK1022838A1 (en) 2000-08-25

Family

ID=26323337

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00101884A HK1022838A1 (en) 1996-12-18 2000-03-28 Phenylethylamine derivatives

Country Status (12)

Country Link
EP (1) EP0951284B1 (pt)
JP (1) JP4116085B2 (pt)
AT (1) ATE251456T1 (pt)
AU (1) AU5620998A (pt)
CA (1) CA2275371C (pt)
DE (1) DE69725467T2 (pt)
DK (1) DK0951284T3 (pt)
ES (1) ES2208967T3 (pt)
HK (1) HK1022838A1 (pt)
HU (1) HU226526B1 (pt)
PT (1) PT951284E (pt)
WO (1) WO1998026775A1 (pt)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7625946B2 (en) 2006-02-24 2009-12-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Propargylated aminoindans, processes for preparation, and uses thereof
US8420696B2 (en) 2005-12-09 2013-04-16 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of low-dose ladostigil for neuroprotection

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
EP1686973A4 (en) * 2003-11-25 2009-03-25 Technion Res & Dev Foundation COMPOSITIONS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND DISEASES
US8097608B2 (en) 2003-11-25 2012-01-17 Technion Research And Development Foundation Ltd. Methods for treatment of cardiovascular disorders and diseases
JP2008526908A (ja) * 2005-01-13 2008-07-24 エフ．ホフマン−ラ ロシュ アーゲー 有用な二置換アミンの新規な一段合成法
US8022104B2 (en) 2005-02-24 2011-09-20 Yissum Research Development Company Of The Hebrew University Of Jerusalem Formulations of ladostigil tartrate
IL311050A (en) 2021-08-23 2024-04-01 Alexander Shulgin Res Institute Inc Deuterated empathogens
US20240287016A1 (en) * 2021-08-23 2024-08-29 Alexander Shulgin Research Institute, Inc. Fluorinated Empathogens

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6408165A (pt) * 1964-07-17 1966-01-18
US3507962A (en) * 1969-05-09 1970-04-21 Thompson Chem Co Hayward Controlling leafminer insects with selected carbamate insecticides,including 3,5-dimethyl-4-dimethylamino-methyl phenyl-n-methylcarbamate
IL74497A (en) * 1985-03-05 1990-02-09 Proterra Ag Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives
HU201906B (en) * 1987-03-04 1991-01-28 Sandoz Ag Process for producing phenyl-carbamate derivative and acid additional salts and pharmaceutical compositions containing them

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8420696B2 (en) 2005-12-09 2013-04-16 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of low-dose ladostigil for neuroprotection
US7625946B2 (en) 2006-02-24 2009-12-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Propargylated aminoindans, processes for preparation, and uses thereof
US8609719B2 (en) 2006-02-24 2013-12-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Propargylated aminoindans, processes for preparation, and uses thereof

Also Published As

Publication number Publication date
JP4116085B2 (ja) 2008-07-09
EP0951284A4 (en) 2002-03-20
CA2275371C (en) 2008-07-29
JP2001506655A (ja) 2001-05-22
HU226526B1 (en) 2009-03-30
CA2275371A1 (en) 1998-06-25
ES2208967T3 (es) 2004-06-16
AU5620998A (en) 1998-07-15
DE69725467T2 (de) 2004-07-22
DE69725467D1 (de) 2003-11-13
EP0951284B1 (en) 2003-10-08
EP0951284A1 (en) 1999-10-27
ATE251456T1 (de) 2003-10-15
PT951284E (pt) 2003-12-31
WO1998026775A1 (en) 1998-06-25
HUP0003180A2 (hu) 2001-01-29
HUP0003180A3 (en) 2002-11-28
DK0951284T3 (da) 2004-02-16

Similar Documents

Publication Publication Date Title
HK1076098A1 (en) Aminoindan derivatives
UA27749C2 (uk) Заміщені циклопропіламіно-1,3,5-триазини, їх оптичні ізомери, рацемічні суміші чи їх солі приєднання нетоксичних фармацевтично прийнятних кислот, що мають фармакологічну активність, спосіб їх одержання (варіанти) та фармацевтична композиція на їх основі
PL335696A1 (en) Substituted 4-arylmethylene-2-imino-2,3-dihydrothiasoles and their derivatives as well as their pharmaceutical application
CA2143636A1 (en) Derivatives of valproic and 2-valproenoic acid amides and use as anticonvulsants
SI1002792T1 (en) 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same
SE0104340D0 (sv) New compounds
BG104561A (en) Aryl fused azapolycyclic compounds
NZ338016A (en) Novel 2-(iminomethyl)amino-phenyl derivatives, preparation, application as medicines and pharmaceutical compositions containing same
SE9601110D0 (sv) Substituted 1,2,3,4-tetrahydronaphthalene derivatives
HK1022838A1 (en) Phenylethylamine derivatives
IL107961A0 (en) Phenoxy- and phenoxyalkyl-piperidines and pharmaceutical compositions containing them
ATE218860T1 (de) Verwendung von 3,4-diphenylchromanen zur herstellung eines arzneimittels zur behandlung bzw. vorbeugung des prostatakarzinoms
HUP0001093A2 (hu) 5-HT2A-antagonista oxazolidinon-származékok, az ezeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
KR970706826A (ko) 포스포디에스테라제 IV 억제제로서의 디아제피노-인돌(Diazepino-Indoles as Phosphodiesterase Ⅳ Inhibitors)
LV10235A (lv) Jauni esteri to iegusanas panemiens farmaceitiska kompozicija arstesanas metode
WO1999021848A3 (en) Novel 1-(n'-(arylalkylaminoalkyl))aminoisoindoles; a new class of dopamine receptor subtype specific ligands
NZ536524A (en) Anticonvulsant and central nervous system-active bis(fluorophenyl)alkylamides
BG101929A (en) Benzamides for neurodegenerative disorder treatment
ES8707951A1 (es) Derivados de tetrazol
IL93051A0 (en) ((5-oxo-2-pyrrolidinyl)methyl)cyclohexaneacetamides,their preparation and pharmaceutical compositions containing them
AU2178199A (en) Azetidinecarboxamide derivatives for the treatment of cns disorders
FI933652A0 (fi) Foerfarande foer framstaellning av 1-osubstituerade 3-aminopyrroler

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20081218