HK1002031A1 - Compounds having antihypertensive and anti-ischemic properties - Google Patents
Compounds having antihypertensive and anti-ischemic propertiesInfo
- Publication number
- HK1002031A1 HK1002031A1 HK98101096A HK98101096A HK1002031A1 HK 1002031 A1 HK1002031 A1 HK 1002031A1 HK 98101096 A HK98101096 A HK 98101096A HK 98101096 A HK98101096 A HK 98101096A HK 1002031 A1 HK1002031 A1 HK 1002031A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- compounds
- antihypertensive
- ischemic properties
- ischemic
- properties
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58788490A | 1990-09-25 | 1990-09-25 | |
PCT/US1991/006990 WO1992005177A1 (en) | 1990-09-25 | 1991-09-25 | Compounds having antihypertensive and anti-ischemic properties |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1002031A1 true HK1002031A1 (en) | 1998-07-24 |
Family
ID=24351576
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK98101096A HK1002031A1 (en) | 1990-09-25 | 1998-02-12 | Compounds having antihypertensive and anti-ischemic properties |
Country Status (14)
Country | Link |
---|---|
US (1) | US5364862A (ja) |
EP (1) | EP0550631B1 (ja) |
JP (1) | JP2505085B2 (ja) |
AT (1) | ATE147074T1 (ja) |
AU (1) | AU654507B2 (ja) |
CA (1) | CA2092305C (ja) |
DE (1) | DE69123974T2 (ja) |
DK (1) | DK0550631T3 (ja) |
ES (1) | ES2095960T3 (ja) |
GR (1) | GR3022207T3 (ja) |
HK (1) | HK1002031A1 (ja) |
MX (1) | MX9203771A (ja) |
SG (1) | SG80526A1 (ja) |
WO (1) | WO1992005177A1 (ja) |
Families Citing this family (93)
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EP0550631B1 (en) * | 1990-09-25 | 1997-01-02 | Rhone-Poulenc Rorer International (Holdings) Inc. | Compounds having antihypertensive and anti-ischemic properties |
FR2685918B1 (fr) * | 1992-01-08 | 1995-06-23 | Union Pharma Scient Appl | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. |
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US5683989A (en) * | 1993-12-17 | 1997-11-04 | Novo Nordisk A/S | Treatment of ischemias by administration of 2,N6 -substituted adenosines |
WO1995018817A1 (fr) * | 1994-01-07 | 1995-07-13 | Laboratoires Upsa | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant |
FR2714907B1 (fr) * | 1994-01-07 | 1996-03-29 | Union Pharma Scient Appl | Nouveaux dérivés de l'Adénosine, leurs procédés de préparation, compositions pharmaceutiques les contenant. |
GB9414208D0 (en) * | 1994-07-14 | 1994-08-31 | Glaxo Group Ltd | Compounds |
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FR2734822B1 (fr) * | 1995-05-30 | 1997-07-04 | Rhone Poulenc Rorer Sa | Nouveaux derives du 2-azabicyclo(2.2.1)heptane, leur preparation et leur application |
US5684159A (en) * | 1995-05-30 | 1997-11-04 | Rhone-Poulenc Rorer S.A. | L-tartaric acid salt of a (1R) diastereomer of a 2-azadihydroxybicyclo 2.2.1!heptane compound and the preparation of 2-azabicyclo 2.2.1!heptane compounds |
ZA9756B (en) * | 1996-01-16 | 1997-07-17 | Warner Lambert Co | Process for preparing 4,6-disubstituted pyrido[3,4-d]-pyrimidines |
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UA51716C2 (uk) * | 1996-07-08 | 2002-12-16 | Авентіс Фармасьютікалз Продактс Інк. | Сполуки, що мають гіпотензивну, кардіопротекторну, анти-ішемічну та антиліполітичну властивості, фармацевтична композиція та способи лікування |
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AU9790998A (en) | 1997-10-07 | 1999-04-27 | Regents Of The University Of California Corporation | Treating occlusive peripheral vascular disease and coronary disease with combinations of heparin and an adenoside a2 agonist, or with adenosine |
GB9723590D0 (en) * | 1997-11-08 | 1998-01-07 | Glaxo Group Ltd | Chemical compounds |
YU44900A (sh) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
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US4843066A (en) * | 1986-11-27 | 1989-06-27 | Nippon Zoki Pharmaceutical Co., Ltd. | Novel adenosine derivatives and pharmaceutical composition containing them as an active ingredient |
HU198950B (en) * | 1986-12-15 | 1989-12-28 | Sandoz Ag | Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds |
EP0277917A3 (en) * | 1987-02-04 | 1990-03-28 | Ciba-Geigy Ag | Certain adenosine 5'-carboxamide derivatives |
US4968697A (en) * | 1987-02-04 | 1990-11-06 | Ciba-Geigy Corporation | 2-substituted adenosine 5'-carboxamides as antihypertensive agents |
CA1340361C (en) * | 1987-04-24 | 1999-02-02 | Whitby Research, Inc. | N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists |
GB8729994D0 (en) * | 1987-12-23 | 1988-02-03 | Glaxo Group Ltd | Chemical compounds |
US4977144A (en) * | 1988-08-02 | 1990-12-11 | Ciba-Geigy Corporation | Imidazo[4,5-b]pyridine derivatives as cardiovascular agents |
AU3820989A (en) * | 1988-08-02 | 1990-02-08 | Ciba-Geigy Ag | 7-amino-3-beta-d-ribofuranosyl-3h-imidazo(4,5-b) pyridin-5-amine derivatives |
GB2226027B (en) * | 1988-12-13 | 1992-05-20 | Sandoz Ltd | Adenosine derivatives,their production and use |
JPH0725785B2 (ja) * | 1989-01-11 | 1995-03-22 | 日本臓器製薬株式会社 | アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物 |
GB8916480D0 (en) * | 1989-07-19 | 1989-09-06 | Glaxo Group Ltd | Chemical process |
EP0550631B1 (en) * | 1990-09-25 | 1997-01-02 | Rhone-Poulenc Rorer International (Holdings) Inc. | Compounds having antihypertensive and anti-ischemic properties |
-
1991
- 1991-09-25 EP EP91917927A patent/EP0550631B1/en not_active Expired - Lifetime
- 1991-09-25 SG SG9603118A patent/SG80526A1/en unknown
- 1991-09-25 CA CA002092305A patent/CA2092305C/en not_active Expired - Fee Related
- 1991-09-25 WO PCT/US1991/006990 patent/WO1992005177A1/en active IP Right Grant
- 1991-09-25 JP JP3516777A patent/JP2505085B2/ja not_active Expired - Fee Related
- 1991-09-25 DE DE69123974T patent/DE69123974T2/de not_active Expired - Fee Related
- 1991-09-25 AT AT91917927T patent/ATE147074T1/de not_active IP Right Cessation
- 1991-09-25 AU AU87266/91A patent/AU654507B2/en not_active Ceased
- 1991-09-25 ES ES91917927T patent/ES2095960T3/es not_active Expired - Lifetime
- 1991-09-25 DK DK91917927.5T patent/DK0550631T3/da active
-
1992
- 1992-06-29 MX MX9203771A patent/MX9203771A/es unknown
- 1992-10-02 US US07/955,783 patent/US5364862A/en not_active Expired - Fee Related
-
1997
- 1997-01-03 GR GR960402653T patent/GR3022207T3/el unknown
-
1998
- 1998-02-12 HK HK98101096A patent/HK1002031A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2505085B2 (ja) | 1996-06-05 |
CA2092305A1 (en) | 1992-03-26 |
ES2095960T3 (es) | 1997-03-01 |
ATE147074T1 (de) | 1997-01-15 |
EP0550631A4 (en) | 1994-08-10 |
JPH05508864A (ja) | 1993-12-09 |
EP0550631A1 (en) | 1993-07-14 |
CA2092305C (en) | 2003-02-11 |
GR3022207T3 (en) | 1997-04-30 |
WO1992005177A1 (en) | 1992-04-02 |
SG80526A1 (en) | 2001-05-22 |
US5364862A (en) | 1994-11-15 |
DK0550631T3 (da) | 1997-01-20 |
AU654507B2 (en) | 1994-11-10 |
AU8726691A (en) | 1992-04-15 |
DE69123974D1 (de) | 1997-02-13 |
EP0550631B1 (en) | 1997-01-02 |
MX9203771A (es) | 1992-09-01 |
DE69123974T2 (de) | 1997-05-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20080925 |