GT200100213A - Inhibidores de espiropirimidin-2,4,6-triona metaloproteinasas. - Google Patents
Inhibidores de espiropirimidin-2,4,6-triona metaloproteinasas.Info
- Publication number
- GT200100213A GT200100213A GT200100213A GT200100213A GT200100213A GT 200100213 A GT200100213 A GT 200100213A GT 200100213 A GT200100213 A GT 200100213A GT 200100213 A GT200100213 A GT 200100213A GT 200100213 A GT200100213 A GT 200100213A
- Authority
- GT
- Guatemala
- Prior art keywords
- ethnic
- heads
- diseases
- spiropirimidin
- triona
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Virology (AREA)
- Pregnancy & Childbirth (AREA)
- Tropical Medicine & Parasitology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24338900P | 2000-10-26 | 2000-10-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
GT200100213A true GT200100213A (es) | 2002-07-03 |
Family
ID=22918584
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT200100213A GT200100213A (es) | 2000-10-26 | 2001-10-25 | Inhibidores de espiropirimidin-2,4,6-triona metaloproteinasas. |
Country Status (32)
Country | Link |
---|---|
EP (1) | EP1332146A2 (fr) |
JP (1) | JP2004518635A (fr) |
KR (1) | KR20040004412A (fr) |
CN (1) | CN1501937A (fr) |
AP (1) | AP2001002318A0 (fr) |
AR (1) | AR035069A1 (fr) |
AU (1) | AU2002210813A1 (fr) |
BG (1) | BG107653A (fr) |
BR (1) | BR0114913A (fr) |
CA (1) | CA2425283A1 (fr) |
CZ (1) | CZ20031083A3 (fr) |
EA (1) | EA005762B1 (fr) |
EC (1) | ECSP034567A (fr) |
EE (1) | EE200300196A (fr) |
GT (1) | GT200100213A (fr) |
HN (1) | HN2001000244A (fr) |
HR (1) | HRP20030332A2 (fr) |
HU (1) | HUP0301577A3 (fr) |
IL (1) | IL154948A0 (fr) |
IS (1) | IS6762A (fr) |
MA (1) | MA26957A1 (fr) |
MX (1) | MXPA03003735A (fr) |
NO (1) | NO20031853L (fr) |
OA (1) | OA12529A (fr) |
PA (1) | PA8531401A1 (fr) |
PE (1) | PE20020589A1 (fr) |
PL (1) | PL366201A1 (fr) |
SK (1) | SK4972003A3 (fr) |
SV (1) | SV2003000705A (fr) |
TN (1) | TNSN01149A1 (fr) |
WO (1) | WO2002034753A2 (fr) |
ZA (1) | ZA200302190B (fr) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DOP2002000333A (es) | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz |
DE60236851D1 (en) | 2001-02-14 | 2010-08-12 | Warner Lambert Co | Pyrimidinmatrixmetalloproteinaseinhibitoren |
DOP2002000332A (es) | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Inhibidores de piridina de metaloproteinasas de la matriz |
PA8539501A1 (es) | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Compuestos triazolo como inhibidores de mmp |
BR0207865A (pt) | 2001-02-14 | 2004-03-23 | Warner Lambert Co | Benzotiadiazinas inibidores de metaloproteinases de matriz |
US6924276B2 (en) | 2001-09-10 | 2005-08-02 | Warner-Lambert Company | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors |
JP4164028B2 (ja) | 2001-10-12 | 2008-10-08 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | アルキンマトリックスメタロプロテイナーゼ阻害剤 |
US6962922B2 (en) | 2001-10-12 | 2005-11-08 | Warner-Lambert Company Llc | Alkynylated quinazoline compounds |
US6894057B2 (en) | 2002-03-08 | 2005-05-17 | Warner-Lambert Company | Oxo-azabicyclic compounds |
AU2003228701A1 (en) * | 2002-04-25 | 2003-11-10 | Bristol-Myers Squibb Company | Spirobarbituric acid derivatives useful as inhibitors of matrix metalloproteases |
JP2005527598A (ja) * | 2002-04-26 | 2005-09-15 | ファイザー・プロダクツ・インク | トリアリール−オキシ−アリール−スピロ−ピリミジン−2,4,6−トリオンメタロプロテイナーゼ阻害剤 |
EP1501833B1 (fr) * | 2002-04-26 | 2005-11-02 | Pfizer Products Inc. | Inhibiteurs de la metalloproteinase n-substitues-heteroaryloxy-aryl-spiro-pyrimidine-2,4,6-trione |
WO2004014923A1 (fr) | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Inhibiteurs de metalloprotease bicycliques condenses avec la pyrimidinone |
AU2003250466A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | 3-isoquinolinone derivatives as matrix metalloproteinase inhiitors |
AU2003249540A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Fused bicyclic metalloproteinase inhibitors |
CA2497658A1 (fr) | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Derives de chromone inhibiteurs de metalloproteinase de matrice |
EP1537098A1 (fr) * | 2002-08-13 | 2005-06-08 | Warner-Lambert Company LLC | Derives monocycliques en tant qu'inhibiteurs de metalloproteinases matricielles |
PA8578101A1 (es) | 2002-08-13 | 2004-05-07 | Warner Lambert Co | Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz |
MXPA05001786A (es) | 2002-08-13 | 2005-04-25 | Warner Lambert Co | Derivados de azaisoquinolina como inhibidores de la metaloproteinasa de matriz. |
AU2003253186A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Fused tetrahydropyridine derivatives as matrix metalloproteinase inhibitors |
JP2006500351A (ja) | 2002-08-13 | 2006-01-05 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | マトリックスメタロプロテアーゼ−13阻害剤としてのピリミジン−2,4−ジオン誘導体 |
WO2004014908A1 (fr) | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Inhibiteurs de metalloproteinases heterobicycliques |
US7208490B2 (en) | 2002-10-07 | 2007-04-24 | Pharmacia & Upjohn Company Llc | Tricyclic tetrahydroquinoline antibacterial agents |
GB0223249D0 (en) * | 2002-10-08 | 2002-11-13 | Amersham Plc | Improved imaging agents |
WO2004084903A1 (fr) * | 2003-03-27 | 2004-10-07 | F. Hoffmann-La Roche Ag | Utilisation d'une trioxopyrimidine pour le traitement et la prevention de l'angiogenese pathologique oculaire |
WO2004084902A1 (fr) * | 2003-03-28 | 2004-10-07 | F. Hoffmann-La Roche Ag | Utilisation d'une trioxopyrimidine dans le traitement de lesions chroniques |
FR2858232B1 (fr) * | 2003-07-29 | 2006-03-03 | Pierre Potier | Utilisation d'un derive de biguanide pour proteger la peau des radiations uvb |
CA2561828C (fr) * | 2004-04-01 | 2012-05-22 | F. Hoffmann-La Roche Ag | Utilisation d'une trioxopyrimidine pour le traitement et la prevention de maladies inflammatoires bronchiques |
DOP2006000268A (es) | 2005-12-22 | 2007-07-31 | Pfizer Prod Inc | Agentes antibacterianos |
US8153166B2 (en) * | 2006-06-08 | 2012-04-10 | Chih-Hsiung Lin | Composition for prophylaxis or treatment of urinary system infection and method thereof |
CN102285934B (zh) * | 2009-01-08 | 2013-08-14 | 四川大学 | 螺环二烯酮衍生物及其制备方法和用途 |
HUE037530T2 (hu) * | 2012-12-10 | 2018-09-28 | Chugai Pharmaceutical Co Ltd | Hidantoinszármazékok |
KR101594506B1 (ko) * | 2014-03-20 | 2016-02-17 | 한국화학연구원 | 골 관련 질환 치료용 조성물 |
BR112016003511B8 (pt) | 2014-06-09 | 2023-10-03 | Chugai Pharmaceutical Co Ltd | Composição farmacêutica que contém derivados de hidantoína e uso dos mesmos |
AU2019387367A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Diarylhydantoin compounds and methods of use thereof |
CN110092790B (zh) * | 2019-06-11 | 2020-07-24 | 东北农业大学 | 一种生物碱类化合物及其制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3714093A (en) * | 1970-05-19 | 1973-01-30 | American Home Prod | Spiro [heterocycloalkyl-2'(1'h)-quinazoline]-4'(3'h)-ones |
CN1295227C (zh) * | 1997-06-21 | 2007-01-17 | 罗赫诊断器材股份有限公司 | 具有抗转移和抗肿瘤活性的巴比土酸衍生物 |
US6265578B1 (en) * | 1999-02-12 | 2001-07-24 | Hoffmann-La Roche Inc. | Pyrimidine-2,4,6-triones |
PA8498701A1 (es) * | 1999-08-12 | 2002-08-26 | Pfizer Prod Inc | Pirimidina-2,4,6-trionas inhibidores de metaloproteinasas |
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2001
- 2001-10-23 EA EA200300306A patent/EA005762B1/ru not_active IP Right Cessation
- 2001-10-23 CA CA002425283A patent/CA2425283A1/fr not_active Abandoned
- 2001-10-23 CZ CZ20031083A patent/CZ20031083A3/cs unknown
- 2001-10-23 EP EP01978721A patent/EP1332146A2/fr not_active Withdrawn
- 2001-10-23 CN CNA018179231A patent/CN1501937A/zh active Pending
- 2001-10-23 AP APAP/P/2001/002318A patent/AP2001002318A0/en unknown
- 2001-10-23 HU HU0301577A patent/HUP0301577A3/hu unknown
- 2001-10-23 IL IL15494801A patent/IL154948A0/xx unknown
- 2001-10-23 JP JP2002537743A patent/JP2004518635A/ja not_active Withdrawn
- 2001-10-23 OA OA1200300123A patent/OA12529A/en unknown
- 2001-10-23 BR BR0114913-0A patent/BR0114913A/pt not_active IP Right Cessation
- 2001-10-23 EE EEP200300196A patent/EE200300196A/xx unknown
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- 2001-10-23 KR KR10-2003-7005753A patent/KR20040004412A/ko not_active Application Discontinuation
- 2001-10-23 WO PCT/IB2001/001986 patent/WO2002034753A2/fr not_active Application Discontinuation
- 2001-10-23 PL PL01366201A patent/PL366201A1/xx not_active Application Discontinuation
- 2001-10-23 AU AU2002210813A patent/AU2002210813A1/en not_active Abandoned
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- 2001-10-25 PE PE2001001060A patent/PE20020589A1/es not_active Application Discontinuation
- 2001-10-25 TN TNTNSN01149A patent/TNSN01149A1/fr unknown
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2003
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