GR3033870T3 - Process for making lipid conjugates. - Google Patents

Process for making lipid conjugates.

Info

Publication number
GR3033870T3
GR3033870T3 GR20000401505T GR20000401505T GR3033870T3 GR 3033870 T3 GR3033870 T3 GR 3033870T3 GR 20000401505 T GR20000401505 T GR 20000401505T GR 20000401505 T GR20000401505 T GR 20000401505T GR 3033870 T3 GR3033870 T3 GR 3033870T3
Authority
GR
Greece
Prior art keywords
lipid
biologically active
acetoacetylated
mixed
active agent
Prior art date
Application number
GR20000401505T
Other languages
English (en)
Inventor
Barbara Yu-Fong Wan
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of GR3033870T3 publication Critical patent/GR3033870T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544—Phospholipids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/21—Hydrocarbon
    • Y10T436/214—Acyclic [e.g., methane, octane, isoparaffin, etc.]
    • Y10T436/216—Unsaturated [e.g., ethylene, diene, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR20000401505T 1992-11-05 2000-07-20 Process for making lipid conjugates. GR3033870T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/972,361 US5329029A (en) 1992-11-05 1992-11-05 Phosphatidylalkanolamine derivatives and their use in generating phospholipid conjugates
PCT/US1993/010601 WO1994009827A1 (en) 1992-11-05 1993-11-05 Process for making lipid conjugates

Publications (1)

Publication Number Publication Date
GR3033870T3 true GR3033870T3 (en) 2000-10-31

Family

ID=25519564

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000401505T GR3033870T3 (en) 1992-11-05 2000-07-20 Process for making lipid conjugates.

Country Status (9)

Country Link
US (2) US5329029A (el)
EP (1) EP0666762B1 (el)
AT (1) ATE194776T1 (el)
DE (1) DE69329069T2 (el)
DK (1) DK0666762T3 (el)
ES (1) ES2148310T3 (el)
GR (1) GR3033870T3 (el)
PT (1) PT666762E (el)
WO (1) WO1994009827A1 (el)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869534A (en) * 1992-05-21 1999-02-09 The Picower Institute For Medical Research Glycosylation of lipids and lipid-containing particles, and diagnostic and therapeutic methods and materials derived therefrom
FR2714830B1 (fr) * 1994-01-10 1996-03-22 Rhone Poulenc Rorer Sa Composition contenant des acides nucléiques, préparation et utilisations.
AUPM747694A0 (en) * 1994-08-16 1994-09-08 Commonwealth Scientific And Industrial Research Organisation Delivery of nucleic acids and peptides
AU1085297A (en) * 1995-11-29 1997-06-19 Nexstar Pharmaceuticals, Inc. Methods for optimizing multicomponent formulations
AUPN741696A0 (en) * 1996-01-05 1996-01-25 Commonwealth Scientific And Industrial Research Organisation Delivery of nucleic acids ii
EP0784984B1 (en) * 1996-01-17 2003-07-02 F. Hoffmann-La Roche Ag Transfection competent molecules
ATE333892T1 (de) * 1996-02-09 2006-08-15 Pi-Wan Cheng Kationisches lipid und rezeptorligand erleichterte gabe von biologisch aktiven molekuelen
US20020102253A1 (en) * 1997-02-25 2002-08-01 Mynott Tracey Lehanne Component of bromelain
WO1999015206A1 (en) * 1997-09-23 1999-04-01 Megabios Corporation Methods for preparing lipids/polynucleotide transfection complexes
US6749865B2 (en) 2000-02-15 2004-06-15 Genzyme Corporation Modification of biopolymers for improved drug delivery
JP2003522806A (ja) 2000-02-15 2003-07-29 ジェンザイム、コーポレーション 改良された薬物送達のための生体高分子の修飾
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
US20030229013A1 (en) * 2001-12-07 2003-12-11 Shih-Kwang Wu Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same
US7299805B2 (en) * 2002-06-07 2007-11-27 Marctec, Llc Scaffold and method for implanting cells
US10858384B2 (en) 2004-03-22 2020-12-08 Kode Biotech Limited Synthetic molecule constructs
ES2654578T3 (es) 2004-03-22 2018-02-14 Kode Biotech Limited Anclajes de membrana sintética
WO2008133534A2 (en) * 2007-04-27 2008-11-06 Kode Biotech Limited Carbohydrate-lipid constructs and their use in preventing or treating viral infection
US7968124B2 (en) * 2004-07-13 2011-06-28 Lyotropic Therapeutics, Inc. Compositions for the reversal and detoxification of anesthetics and other compounds and methods of their use
US20090162277A1 (en) * 2005-11-03 2009-06-25 Clemson University Lysophospholipids Solubilized Single-Walled Carbon Nanotubes
US8426152B2 (en) 2007-01-03 2013-04-23 Lamdagen Corporation Enzymatic assay for LSPR
US8105809B2 (en) * 2008-07-03 2012-01-31 Accera, Inc. Enzymatic synthesis of acetoacetate esters and derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2645866B1 (fr) * 1989-04-17 1991-07-05 Centre Nat Rech Scient Nouvelles lipopolyamines, leur preparation et leur emploi
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
EP0625207A1 (en) * 1991-12-17 1994-11-23 The Regents Of The University Of California Gene therapy for cystic fibrosis transmembrane conductance regulator activity (cftr)

Also Published As

Publication number Publication date
US5329029A (en) 1994-07-12
EP0666762A1 (en) 1995-08-16
WO1994009827A1 (en) 1994-05-11
EP0666762B1 (en) 2000-07-19
ES2148310T3 (es) 2000-10-16
PT666762E (pt) 2000-12-29
US5451661A (en) 1995-09-19
DK0666762T3 (da) 2000-09-18
DE69329069T2 (de) 2000-12-21
DE69329069D1 (de) 2000-08-24
ATE194776T1 (de) 2000-08-15

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