GR1007520B - Ταυτοχρονη εκχυλιση και σχηματισμος συμπλοκων εγκλεισμου των δραστικων συστατικων της προπολης με υδροξυπροπυλο-β-κυκλοδεξτρινη - Google Patents

Ταυτοχρονη εκχυλιση και σχηματισμος συμπλοκων εγκλεισμου των δραστικων συστατικων της προπολης με υδροξυπροπυλο-β-κυκλοδεξτρινη

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Publication number
GR1007520B
GR1007520B GR20100100695A GR20100100695A GR1007520B GR 1007520 B GR1007520 B GR 1007520B GR 20100100695 A GR20100100695 A GR 20100100695A GR 20100100695 A GR20100100695 A GR 20100100695A GR 1007520 B GR1007520 B GR 1007520B
Authority
GR
Greece
Prior art keywords
extraction
cyclodextrin
formation
active components
inclusion complexes
Prior art date
Application number
GR20100100695A
Other languages
English (en)
Inventor
Ιωαννης Μουρτζινος
Παναγιωτα Δραγανη
Αννα Πατερα
Νικολαος Κουτσιανας
Original Assignee
Apivita - Καλλυντικα - Διαιτητικα - Φαρμακα Ανωνυμη Εμπορικη Και Βιοτεχνικη Εταιρεια,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apivita - Καλλυντικα - Διαιτητικα - Φαρμακα Ανωνυμη Εμπορικη Και Βιοτεχνικη Εταιρεια, filed Critical Apivita - Καλλυντικα - Διαιτητικα - Φαρμακα Ανωνυμη Εμπορικη Και Βιοτεχνικη Εταιρεια,
Priority to GR20100100695A priority Critical patent/GR1007520B/el
Priority to EP11797026.9A priority patent/EP2646041A1/en
Priority to PCT/GR2011/000054 priority patent/WO2012073051A1/en
Publication of GR1007520B publication Critical patent/GR1007520B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988—Honey; Royal jelly, Propolis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L21/00—Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
    • A23L21/20—Products from apiculture, e.g. royal jelly or pollen; Substitutes therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/738—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Η εκχύλιση της πρόπολης γίνεται σε θερμοκρασία περιβάλλοντος, χωρίς τη χρήση υπερήχων ή μικροκυμάτων, με εισαγωγή στο σύστημα του διαλύτη εκχύλισης της υδροξυπρόπυλο-β-κυκλοδεξτρίνης. Η διαλυτότητα των δραστικών συστατικών αυξάνεται με τη δημιουργία συμπλοκών εγκλεισμού κατά τη διάρκεια της εκχύλισης και αυτό έχει ως αποτέλεσμα την αύξηση της απόδοσης της εκχύλισης. Το τελικό εκχύλισμα είναι πιο σταθερό και ταυτόχρονα έχει συγκεκριμένες προδιαγραφές ως προς την αντιοξειδωτική ικανότητα και την συνολική περιεκτικότητα σε πολυφαινόλες και φλαβονοειδή. Το εκχύλισμα μπορεί να χρησιμοποιηθεί για τον εμπλουτισμό τροφίμων, παρασκευή συμπληρωμάτων διατροφής, καλλυντικών προϊόντων περιποίησης προσώπου και σώματος και φαρμάκων.
GR20100100695A 2010-12-01 2010-12-02 Ταυτοχρονη εκχυλιση και σχηματισμος συμπλοκων εγκλεισμου των δραστικων συστατικων της προπολης με υδροξυπροπυλο-β-κυκλοδεξτρινη GR1007520B (el)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GR20100100695A GR1007520B (el) 2010-12-02 2010-12-02 Ταυτοχρονη εκχυλιση και σχηματισμος συμπλοκων εγκλεισμου των δραστικων συστατικων της προπολης με υδροξυπροπυλο-β-κυκλοδεξτρινη
EP11797026.9A EP2646041A1 (en) 2010-12-02 2011-11-30 Extraction and formation of inclusion complexes of propolis active components with hydroxypropyl - beta - cyclodextrin
PCT/GR2011/000054 WO2012073051A1 (en) 2010-12-01 2011-11-30 Extraction and formation of inclusion complexes of propolis active components with hydroxypropyl - beta - cyclodextrin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20100100695A GR1007520B (el) 2010-12-02 2010-12-02 Ταυτοχρονη εκχυλιση και σχηματισμος συμπλοκων εγκλεισμου των δραστικων συστατικων της προπολης με υδροξυπροπυλο-β-κυκλοδεξτρινη

Publications (1)

Publication Number Publication Date
GR1007520B true GR1007520B (el) 2012-02-02

Family

ID=44534962

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20100100695A GR1007520B (el) 2010-12-01 2010-12-02 Ταυτοχρονη εκχυλιση και σχηματισμος συμπλοκων εγκλεισμου των δραστικων συστατικων της προπολης με υδροξυπροπυλο-β-κυκλοδεξτρινη

Country Status (3)

Country Link
EP (1) EP2646041A1 (el)
GR (1) GR1007520B (el)
WO (1) WO2012073051A1 (el)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104886577A (zh) * 2015-06-16 2015-09-09 福建省农业科学院农业工程技术研究所 一种李果多酚的制备方法
GR1009175B (el) * 2016-06-13 2017-12-18 Apivita Καλλυντικα Διαιτητικα Φαρμακα Ανωνυμη Εμπορικη Και Βιοτεχνικη Εταιρεια Συνδυασμος εκχυλισματος μικροφυκους nannochloropsis gaditana και εκχυλισματος προπολης ως δραστικου συστατικου σε καλλυντικοτεχνικες φορμουλες για δερματικη χρηση

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160051594A1 (en) 2013-04-05 2016-02-25 Manuka Health New Zealand Limited Therapeutic Compositions and Uses Thereof
WO2022045371A1 (ja) * 2020-08-31 2022-03-03 合同会社レビアスファーマ 組成物およびその組成物の製造方法、脂溶性成分の吸収性を向上させる方法、脂溶性成分の抽出効率を向上させる方法、脂溶性成分

Citations (1)

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KR950002774B1 (ko) * 1992-08-12 1995-03-27 주식회사유한양행 가용화 프로폴리스 조성물

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KR101563308B1 (ko) * 2008-11-11 2015-10-26 씨에스피씨 종콰이 팔마씨우티컬 테크놀로지 (스자좡) 컴퍼니 리미티드 피노셈브린과 사이클로덱스트린 또는 그의 유도체와의 포접 화합물

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KR950002774B1 (ko) * 1992-08-12 1995-03-27 주식회사유한양행 가용화 프로폴리스 조성물

Non-Patent Citations (4)

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Title
CONEAC G ET AL.: "Propolis extract/beta-cyclodextrin nanoparticles: synthesis, physico-chemical and multivariate analyses", JOURNAL OF AGROALIMENTARY PROCESSES AND TECHNOLOGIES, vol. 14, no. 1, 2008, :, pages 58 - 70, XP002658835 *
DATABASE WPI Week 199707, Derwent World Patents Index; AN 1997-075510, XP002658834 *
KALOGEROPOULOS N ET AL.: "Encapsulation of complex extracts in beta-cyclodextrin: an application to propolis ethanolic extract", JOURNAL OF MICROENCAPSULATION, vol. 26, no. 7, 2009, pages 603 - 613, XP002658837 *
NAFADY A ET AL.: "Cyclodextrin-enclosed substances of Brazilian propolis", CHEMICAL PHARMACEUTICAL BULLETIN, vol. 51, no. 8, 2003, pages 984 - 985, XP002658836 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104886577A (zh) * 2015-06-16 2015-09-09 福建省农业科学院农业工程技术研究所 一种李果多酚的制备方法
CN104886577B (zh) * 2015-06-16 2017-03-15 福建省农业科学院农业工程技术研究所 一种李果多酚的制备方法
GR1009175B (el) * 2016-06-13 2017-12-18 Apivita Καλλυντικα Διαιτητικα Φαρμακα Ανωνυμη Εμπορικη Και Βιοτεχνικη Εταιρεια Συνδυασμος εκχυλισματος μικροφυκους nannochloropsis gaditana και εκχυλισματος προπολης ως δραστικου συστατικου σε καλλυντικοτεχνικες φορμουλες για δερματικη χρηση

Also Published As

Publication number Publication date
WO2012073051A1 (en) 2012-06-07
EP2646041A1 (en) 2013-10-09

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Effective date: 20120322