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Process for the manufacture of a steroid lactone

Abstract

An 18, 20-lactone of a D 4-3-oxo-11a -acyloxy-20-hydroxy-pregnene -18- acid is obtained by heating an 18, 20-lactone of a 2-bromo -3- oxo-11a -acyloxy -20- hydroxy -5a - pregnane -18- acid with a lithium halide in a dialkyl-formamide, if desired in the presence of lithium carbonate, e.g. the reaction may be effected with lithium chloride above 100 DEG C. Specifications 973,143, 973,144 and 973,145 are referred to.

Classifications

C07J71/00 Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
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GB978723A

United Kingdom

Current Assignee
BASF Schweiz AG

Worldwide applications
1961 GB

Application GB2660361A events
Expired