GB969359A - Improvements in or relating to phenthiazine derivatives - Google Patents
Improvements in or relating to phenthiazine derivativesInfo
- Publication number
- GB969359A GB969359A GB4491861A GB4491861A GB969359A GB 969359 A GB969359 A GB 969359A GB 4491861 A GB4491861 A GB 4491861A GB 4491861 A GB4491861 A GB 4491861A GB 969359 A GB969359 A GB 969359A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reacting
- group
- phenothiazine
- carbon atoms
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical class C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- -1 pyrrolidino, morpholino, piperidino piperazino Chemical group 0.000 abstract 3
- CLXYGCPNHLXLPD-UHFFFAOYSA-N 3-nitro-10h-phenothiazine Chemical compound C1=CC=C2SC3=CC([N+](=O)[O-])=CC=C3NC2=C1 CLXYGCPNHLXLPD-UHFFFAOYSA-N 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- PYSGFFTXMUWEOT-UHFFFAOYSA-N 3-(dimethylamino)propan-1-ol Chemical compound CN(C)CCCO PYSGFFTXMUWEOT-UHFFFAOYSA-N 0.000 abstract 1
- RTJZBBSYKAIPAF-UHFFFAOYSA-N 3-(dimethylamino)propyl 3-nitrophenothiazine-10-carboxylate Chemical compound [N+](=O)([O-])C=1C=CC=2N(C3=CC=CC=C3SC2C1)C(=O)OCCCN(C)C RTJZBBSYKAIPAF-UHFFFAOYSA-N 0.000 abstract 1
- NDRQUXNAAPWWMA-UHFFFAOYSA-N 3-nitrophenothiazine-10-carbonyl chloride Chemical compound [N+](=O)([O-])C=1C=CC=2N(C3=CC=CC=C3SC2C1)C(=O)Cl NDRQUXNAAPWWMA-UHFFFAOYSA-N 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003474 anti-emetic effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 229940125683 antiemetic agent Drugs 0.000 abstract 1
- 239000002111 antiemetic agent Substances 0.000 abstract 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 230000000911 decarboxylating effect Effects 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000008016 pharmaceutical coating Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229950000688 phenothiazine Drugs 0.000 abstract 1
- 150000002990 phenothiazines Chemical class 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 150000003873 salicylate salts Chemical class 0.000 abstract 1
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003204 tranquilizing agent Substances 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR847019A FR1403607A (fr) | 1960-12-15 | 1960-12-15 | Nouveaux dérivés de la phénothiazine et leur procédé de préparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB969359A true GB969359A (en) | 1964-09-09 |
Family
ID=8744819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4491861A Expired GB969359A (en) | 1960-12-15 | 1961-12-14 | Improvements in or relating to phenthiazine derivatives |
Country Status (6)
| Country | Link |
|---|---|
| CH (1) | CH408925A (enrdf_load_stackoverflow) |
| DE (1) | DE1161902B (enrdf_load_stackoverflow) |
| ES (1) | ES272766A1 (enrdf_load_stackoverflow) |
| FR (1) | FR1403607A (enrdf_load_stackoverflow) |
| GB (1) | GB969359A (enrdf_load_stackoverflow) |
| NL (1) | NL271900A (enrdf_load_stackoverflow) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1056611B (de) * | 1955-11-15 | 1959-05-06 | Rhone Poulenc Sa | Verfahren zur Herstellung von Phenthiazinderivaten |
-
0
- NL NL271900D patent/NL271900A/xx unknown
-
1960
- 1960-12-15 FR FR847019A patent/FR1403607A/fr not_active Expired
-
1961
- 1961-12-01 CH CH1400461A patent/CH408925A/fr unknown
- 1961-12-04 DE DE1961S0076981 patent/DE1161902B/de active Pending
- 1961-12-07 ES ES0272766A patent/ES272766A1/es not_active Expired
- 1961-12-14 GB GB4491861A patent/GB969359A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR1403607A (fr) | 1965-06-25 |
| CH408925A (fr) | 1966-03-15 |
| NL271900A (enrdf_load_stackoverflow) | |
| ES272766A1 (es) | 1962-03-01 |
| DE1161902B (de) | 1964-01-30 |
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