GB873464A - New orally effective blood sugar lowering substances - Google Patents

New orally effective blood sugar lowering substances

Info

Publication number
GB873464A
GB873464A GB11624/59A GB1162459A GB873464A GB 873464 A GB873464 A GB 873464A GB 11624/59 A GB11624/59 A GB 11624/59A GB 1162459 A GB1162459 A GB 1162459A GB 873464 A GB873464 A GB 873464A
Authority
GB
United Kingdom
Prior art keywords
alkylene2
alkylene1
sulphonyl
blood sugar
sugar lowering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB11624/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ERWIN DIEHL
Original Assignee
ERWIN DIEHL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ERWIN DIEHL filed Critical ERWIN DIEHL
Publication of GB873464A publication Critical patent/GB873464A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention comprises compounds of the formula X-Alkylene1-Z-SO2-NH-CO-NH. Alkylene2-Y, wherein X is a halogen atom, Z is a 1:4-phenylene or 1:4-cyclohexylene radical, Y is a halogen or hydrogen atom, Alkylene1 and Z together containing up to 8 carbon atoms and Alkylene2 containing 3-8 carbon atoms; more especially the N1-(4-halomethylphenyl)-sulphonyl-and N1-(4-halomethylcyclohexyl)-sulphonyl-, N2-alkyl ureas. The compounds are prepared by known methods for the preparation of sulphonyl ureas, for example by reacting a sulphonamide X-Alkylene1-Z-SO2-NH2 with an isocyanate Y-Alkylene2-NCO, in the presence of an alkali p metal hydroxide as a condensing agent and in a ketone solvent such as acetone. Preferred products are N1-p-chloromethylphenylsulphonyl-N2-propyl-and N-butyl urea and N1-p-chloromethylcyclo-hexylsulphonyl-N2-butyl urea. Specifications 792,776, 794,552, 808,071 and 808,073 are referred to.
GB11624/59A 1958-04-05 1959-04-06 New orally effective blood sugar lowering substances Expired GB873464A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT873464X 1958-04-05

Publications (1)

Publication Number Publication Date
GB873464A true GB873464A (en) 1961-07-26

Family

ID=3682557

Family Applications (1)

Application Number Title Priority Date Filing Date
GB11624/59A Expired GB873464A (en) 1958-04-05 1959-04-06 New orally effective blood sugar lowering substances

Country Status (1)

Country Link
GB (1) GB873464A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449417A (en) * 1964-12-28 1969-06-10 Hoechst Ag Benzenesulphonyl-ureas and process for preparing them

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449417A (en) * 1964-12-28 1969-06-10 Hoechst Ag Benzenesulphonyl-ureas and process for preparing them

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