GB861900A - New amino ethers and their process of preparation - Google Patents

New amino ethers and their process of preparation

Info

Publication number
GB861900A
GB861900A GB26884/59A GB2688459A GB861900A GB 861900 A GB861900 A GB 861900A GB 26884/59 A GB26884/59 A GB 26884/59A GB 2688459 A GB2688459 A GB 2688459A GB 861900 A GB861900 A GB 861900A
Authority
GB
United Kingdom
Prior art keywords
ethyl
formula
norpin
homomyrtenyl
menth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB26884/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE581863D priority Critical patent/BE581863A/xx
Priority to NL246462D priority patent/NL246462A/xx
Application filed by Individual filed Critical Individual
Priority to GB26884/59A priority patent/GB861900A/en
Priority to DEG28093A priority patent/DE1126383B/en
Priority to FR833056A priority patent/FR39M/en
Priority to DEG30156A priority patent/DE1157607B/en
Priority to FR834570A priority patent/FR1266743A/en
Publication of GB861900A publication Critical patent/GB861900A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/28—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system containing seven carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline

Abstract

The invention comprises amino-ethers of the formula R.O.CH2.CH2.N(R1)R2, wherein R is homomyrtenyl, i.e. 2-(6 : 6-dimethyl-norpin-2-en-2-yl)-ethyl, isobornyl or p-menth-1-en-8-yl radical and R1 and R2 are each alkyl, e.g. ethyl, radicals or form with the nitrogen atom a heterocyclic ring such as piperidine, and their preparation by condensing an amino-halogeno-alkane of the formula R2(R1)N.CH2.CH2.Hal with an alcohol ROH in the presence of an alkali metal amide.ALSO:Preparations for use as local an sthetics, analgesics and anti-spasmodics comprise compounds of the formula R.O.CH2.CH2.N(R1)R2 wherein R is a homomyrtenyl, i.e. 2-(6 : 6-dimethyl - norpin - 2 - en - 2 - yl) - ethyl, isobornyl or p-menth-1-en-8-yl radical and R1 and R2 are each alkyl, e.g. ethyl, radicals, or together with the nitrogen form a heterocyclic nucleus, in association with a vehicle. Examples describe compositions containing 2-homomyrtenyloxy - 1 - diethylamino ethane (a) in association with ointment and suppository media, (b) as a mouth-wash containing glycerine, (c) as a throat-wash with opium extract, alcohol aqueous sugar solution and cherry laurel water, (d) as a glycerine composition containing resorcinol and (e) as drops containing chloroformed water.
GB26884/59A 1959-08-06 1959-08-06 New amino ethers and their process of preparation Expired GB861900A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
BE581863D BE581863A (en) 1959-08-06
NL246462D NL246462A (en) 1959-08-06
GB26884/59A GB861900A (en) 1959-08-06 1959-08-06 New amino ethers and their process of preparation
DEG28093A DE1126383B (en) 1959-08-06 1959-10-06 Process for the production of locally anesthetically effective amino ethers
FR833056A FR39M (en) 1959-08-06 1960-07-15 New drug usable as local anesthetic and spasmolytic, based on homomyrtenyloxy-2 diethylamino-1 ethane
DEG30156A DE1157607B (en) 1959-08-06 1960-07-26 Process for the production of locally anesthetically effective amino ethers
FR834570A FR1266743A (en) 1959-08-06 1960-07-30 New amino ethers-oxides and their preparation process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB26884/59A GB861900A (en) 1959-08-06 1959-08-06 New amino ethers and their process of preparation

Publications (1)

Publication Number Publication Date
GB861900A true GB861900A (en) 1961-03-01

Family

ID=10250724

Family Applications (1)

Application Number Title Priority Date Filing Date
GB26884/59A Expired GB861900A (en) 1959-08-06 1959-08-06 New amino ethers and their process of preparation

Country Status (5)

Country Link
BE (1) BE581863A (en)
DE (2) DE1126383B (en)
FR (2) FR39M (en)
GB (1) GB861900A (en)
NL (1) NL246462A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK156825B (en) * 1979-12-14 1989-10-09 Egyt Gyogyszervegyeszeti Gyar ANALOGUE PROCEDURE FOR PREPARING A BASIC ETHER OR A PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALT OR QUATERNARY SALT THEREOF
US6537548B1 (en) * 2000-07-27 2003-03-25 The Regents Of The University Of California Antibodies specific for ungulate PrP

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3397053A (en) * 1965-08-11 1968-08-13 Scm Corp Method of killing plants

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2316625A (en) * 1940-08-21 1943-04-13 Hercules Powder Co Ltd Terpene halo-alkyl-ether-amine condensation product
DE941908C (en) * 1953-01-23 1956-04-19 Basf Ag Process for the production of basic ethers
DE955595C (en) * 1954-04-15 1957-01-03 Thomae Gmbh Dr K Process for the production of spasmolytically effective basic ethers of endocyclically substituted carbinols and their salts

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK156825B (en) * 1979-12-14 1989-10-09 Egyt Gyogyszervegyeszeti Gyar ANALOGUE PROCEDURE FOR PREPARING A BASIC ETHER OR A PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALT OR QUATERNARY SALT THEREOF
US6537548B1 (en) * 2000-07-27 2003-03-25 The Regents Of The University Of California Antibodies specific for ungulate PrP
US7094553B2 (en) * 2000-07-27 2006-08-22 The Regents Of The University Of California Antibodies specific for ungulate PrP

Also Published As

Publication number Publication date
FR1266743A (en) 1961-07-17
DE1126383B (en) 1962-03-29
FR39M (en) 1960-11-28
NL246462A (en)
DE1157607B (en) 1963-11-21
BE581863A (en)

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