GB720116A - Improvements in or relating to sterile, broad-spectrum antibiotic-containing wound dressings - Google Patents

Improvements in or relating to sterile, broad-spectrum antibiotic-containing wound dressings

Info

Publication number
GB720116A
GB720116A GB852152A GB852152A GB720116A GB 720116 A GB720116 A GB 720116A GB 852152 A GB852152 A GB 852152A GB 852152 A GB852152 A GB 852152A GB 720116 A GB720116 A GB 720116A
Authority
GB
United Kingdom
Prior art keywords
mixture
per cent
sterile
broad
sterilely
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB852152A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
Wyeth Holdings LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US720116XA priority Critical
Application filed by Wyeth Holdings LLC filed Critical Wyeth Holdings LLC
Publication of GB720116A publication Critical patent/GB720116A/en
Application status is Expired legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/34Oils, fats, waxes or natural resins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/46Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

Abstract

A method of prepairing a wound dressing comprises preparing a sterile mixture of a dispersing agent, anhydrous lanolin, petroleum, a wax, a mineral oil and a broad-spectrum antibiotic and sterilely adding the mixture to a sterile carrier. The sterile mixture comprises 1-10 per cent. of glyceryl monostearate or other monoglyceryl ester of a long chain fatty acid, i.e. one which contains at least twelve carbon atoms in the molecule, or an ester of cholesterol, 5-20 per cent. anhydrous lanolin, 10-30 per cent. petrolatum, 5-20 per cent wax e.g. ceresin, paraffin wax or beeswax, 0.1 per cent.- 5 per cent. of a broad-spectrum antibiotic such as aureomycin, chloramphenicol, terramycin or their therapeutically effective salts and a mineral oil, the proportions being such that the mixture melts between 33 DEG C. and 44 DEG C. The mixture may be made by sterilely preparing a mixture of the dispersing agent, lanolin, petrolatum and wax and adding it sterilely to a mixture of pulverised antibiotic and mineral oil. The resulting ointment is then applied to a sterile carrier e.g. gauze. The finished dressing is sterilely heat sealed within an aluminium foil envelope laminated on the inside to a film of copolymer of vinyl chloride and vinyl acetate by a suitable adhesive. The term broad-spectrum used throughout the Specification covers antibiotics which are effective against both Gram-positive and Gram-negative bacteria e.g. tetracycline, chlortetracycline oxytetracycline bromotetracyline, chloramphenicol, streptomycin dihydiostreptomycin, viomycin, and neomycin.
GB852152A 1951-04-24 1952-04-03 Improvements in or relating to sterile, broad-spectrum antibiotic-containing wound dressings Expired GB720116A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US720116XA true 1951-04-24 1951-04-24

Publications (1)

Publication Number Publication Date
GB720116A true GB720116A (en) 1954-12-15

Family

ID=22105000

Family Applications (1)

Application Number Title Priority Date Filing Date
GB852152A Expired GB720116A (en) 1951-04-24 1952-04-03 Improvements in or relating to sterile, broad-spectrum antibiotic-containing wound dressings

Country Status (1)

Country Link
GB (1) GB720116A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2190289A (en) * 1986-05-14 1987-11-18 Cuxson Gerrard & Co Limited Applicators for applying medicated liquids to the skin
WO1996036315A1 (en) * 1995-05-20 1996-11-21 Smith & Nephew Plc Sterilisable paste product for topical application
EP3170498A4 (en) * 2014-07-15 2018-03-14 Mitsui Chemicals, Inc. Therapeutic agent for surface wound, and material for treating surface wound

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2190289A (en) * 1986-05-14 1987-11-18 Cuxson Gerrard & Co Limited Applicators for applying medicated liquids to the skin
GB2190289B (en) * 1986-05-14 1990-07-04 Cuxson Gerrard & Co Limited Applicators for applying medicated liquids to the skin
WO1996036315A1 (en) * 1995-05-20 1996-11-21 Smith & Nephew Plc Sterilisable paste product for topical application
EP3170498A4 (en) * 2014-07-15 2018-03-14 Mitsui Chemicals, Inc. Therapeutic agent for surface wound, and material for treating surface wound

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