GB692334A - Improvements in or relating to vitamin preparation - Google Patents
Improvements in or relating to vitamin preparationInfo
- Publication number
- GB692334A GB692334A GB20486/51A GB2048651A GB692334A GB 692334 A GB692334 A GB 692334A GB 20486/51 A GB20486/51 A GB 20486/51A GB 2048651 A GB2048651 A GB 2048651A GB 692334 A GB692334 A GB 692334A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vitamin
- propylene glycol
- water
- preparation
- soluble
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A stable, substantially anhydrous (not more than 1, and preferably 0.5, per cent water), homogeneous liquid polyvitamin preparation comprises both water-soluble and fat-soluble vitamins in a vehicle consisting essentially of propylene glycol and a water-soluble polyoxy-alkylene oxide derivative of a fatty acid (not less than 12 C atoms) partial ester of a hexitan, said vehicle constituting the major proportion, preferably at least 80 per cent by weight, of the preparation, the propylene glycol being 0.5 to 2 parts by weight per part of the hexitan derivative. Polyoxyalkylene derivatives of sorbitan with acids such as lauric, stearic, palmitic and oleic, where the alkylene oxide is ethylene oxide or propylene oxide, present as 16 to 25 oxide groupings, e.g. "Tweens" (Registered Trade Mark), are preferred. The "Tween" is preferably dried in vacuo. One or more fat soluble vitamins are dissolved in the "Tween," the water-soluble vitamins are dissolved in the propylene glycol, and the solutions so formed are mixed, the operations being carried out in the presence of an inert gas e.g. nitrogen or CO2. If the propylene glycol has not been previously dried, the vitamin preparation is dried over an agent insoluble in propylene glycol e.g. anhydrous sodium sulphate, anhydrous calcium sulphate or activated alumina. In one example, vitamin A, vitamin D2, oil of limes and d-pantothenyl alcohol are dissolved in polyoxyethylene sorbitan mono-oleate at 50 DEG C. under CO2. To this is added a solution of urea, nicotinamide, riboflavin, ascorbic acid, pyridoxine hydrochloride, thiamin HCl and saccharin at 50 DEG C. Other specified vitamins are vitamin A palmitate, vitamin A acetate, thiamine mono-nitrate and a -tocopherol acetate. The multi-vitamin preparation may be mixed with orange juice, milk, cereals, strained or chopped meats, vegetables, fruits, puddings, soups and other foods. Specification 588,298 is referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US692334XA | 1950-11-29 | 1950-11-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB692334A true GB692334A (en) | 1953-06-03 |
Family
ID=22087591
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB20486/51A Expired GB692334A (en) | 1950-11-29 | 1951-08-30 | Improvements in or relating to vitamin preparation |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB692334A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3149037A (en) * | 1962-09-07 | 1964-09-15 | Hoffmann La Roche | Vitamin compositions |
-
1951
- 1951-08-30 GB GB20486/51A patent/GB692334A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3149037A (en) * | 1962-09-07 | 1964-09-15 | Hoffmann La Roche | Vitamin compositions |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3760699D1 (en) | Enteral diet product, agent and methods for its production | |
US6056971A (en) | Method for enhancing dissolution properties of relatively insoluble dietary supplements and product incorporating same | |
EP0165352A3 (en) | Clear micellized solutions of fat soluble essential nutrients | |
US3692907A (en) | Treating viral infections with bis-basic ethers and thioethers of fluorenone and fluorene and pharmaceutical compositons of the same | |
US6143735A (en) | Agent for treating heart diseases | |
CN101553137B (en) | There is the Fructus Mali pumilae of high polyphenolic content | |
PT84663A (en) | Process for the preparation of new pharmaceutical preparations with extended release comprising active compounds with very low solubility especially substituted dihydropyridines | |
GB1405088A (en) | Slow release formulation | |
US2822317A (en) | Aqueous iron-ascorbic acid preparation | |
JPH0332558B2 (en) | ||
GB946086A (en) | Parenteral aqueous solutions of fat-soluble vitamins | |
GB1279895A (en) | O-acyl-lysergols and process for preparing them | |
US3436459A (en) | Fat soluble vitamin compositions | |
GB692334A (en) | Improvements in or relating to vitamin preparation | |
GB1499240A (en) | Ascorbic acid preparations | |
IE34283L (en) | Sulphonamido-anthranilic acid derivatives | |
US6071963A (en) | Water dispersible compositions | |
US2953496A (en) | Vitamin emulsion | |
US2518230A (en) | Aqueous solutions of lipoid-soluble vitamins | |
GB588298A (en) | Improvements in or relating to vitamin compositions | |
US4078065A (en) | Organic compounds | |
US2463461A (en) | Aqueous solutions of riboflavin | |
GB933108A (en) | Improvements in or relating to pharmaceutical iron preparations | |
Melcher et al. | A serologically active polysaccharide from Trichinella spiralis | |
CA2062970A1 (en) | Benzophenanthridine alkaloids for topical acne treatment |