GB683773A - New quinoline derivatives - Google Patents
New quinoline derivativesInfo
- Publication number
- GB683773A GB683773A GB5312/50A GB531250A GB683773A GB 683773 A GB683773 A GB 683773A GB 5312/50 A GB5312/50 A GB 5312/50A GB 531250 A GB531250 A GB 531250A GB 683773 A GB683773 A GB 683773A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amino
- chloro
- methochloride
- quinaldine
- methylaminopyrimidyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title abstract 2
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- SMUQFGGVLNAIOZ-UHFFFAOYSA-N methylquinoline Natural products C1=CC=CC2=NC(C)=CC=C21 SMUQFGGVLNAIOZ-UHFFFAOYSA-N 0.000 abstract 5
- 150000003839 salts Chemical group 0.000 abstract 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 4
- VUQUOGPMUUJORT-UHFFFAOYSA-N methyl 4-methylbenzenesulfonate Chemical class COS(=O)(=O)C1=CC=C(C)C=C1 VUQUOGPMUUJORT-UHFFFAOYSA-N 0.000 abstract 3
- 238000010992 reflux Methods 0.000 abstract 3
- FVAUCKIRQBBSSJ-UHFFFAOYSA-M sodium iodide Chemical compound [Na+].[I-] FVAUCKIRQBBSSJ-UHFFFAOYSA-M 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- LQNUZADURLCDLV-UHFFFAOYSA-N nitrobenzene Chemical compound [O-][N+](=O)C1=CC=CC=C1 LQNUZADURLCDLV-UHFFFAOYSA-N 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- ZPTFYJKAWRUABO-UHFFFAOYSA-N 4-n,2-dimethylquinoline-4,6-diamine Chemical compound C1=C(N)C=C2C(NC)=CC(C)=NC2=C1 ZPTFYJKAWRUABO-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003973 alkyl amines Chemical class 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- SMWDFEZZVXVKRB-UHFFFAOYSA-N anhydrous quinoline Natural products N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000004683 dihydrates Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910001502 inorganic halide Inorganic materials 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000003230 pyrimidines Chemical class 0.000 abstract 1
- 238000011946 reduction process Methods 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 235000009518 sodium iodide Nutrition 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000000654 trypanocidal effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE501634D BE501634A (en:Method) | 1950-03-02 | ||
| GB5312/50A GB683773A (en) | 1950-03-02 | 1950-03-02 | New quinoline derivatives |
| US210631A US2591545A (en) | 1950-03-02 | 1951-02-12 | Di-quaternary salts of pyrimidylaminoquinolines |
| FR1056758D FR1056758A (fr) | 1950-03-02 | 1951-02-24 | Fabrication de dérivés nouveaux de la quinoléine |
| DEI3846A DE852855C (de) | 1950-03-02 | 1951-03-03 | Verfahren zur Herstellung von neuen diquartaeren Salzen von Pyrimidylaminochinolinen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5312/50A GB683773A (en) | 1950-03-02 | 1950-03-02 | New quinoline derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB683773A true GB683773A (en) | 1952-12-03 |
Family
ID=9793738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5312/50A Expired GB683773A (en) | 1950-03-02 | 1950-03-02 | New quinoline derivatives |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US2591545A (en:Method) |
| BE (1) | BE501634A (en:Method) |
| DE (1) | DE852855C (en:Method) |
| FR (1) | FR1056758A (en:Method) |
| GB (1) | GB683773A (en:Method) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1383409A (en) * | 1972-09-09 | 1974-02-12 | Pfizer Ltd | Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them |
-
0
- BE BE501634D patent/BE501634A/xx unknown
-
1950
- 1950-03-02 GB GB5312/50A patent/GB683773A/en not_active Expired
-
1951
- 1951-02-12 US US210631A patent/US2591545A/en not_active Expired - Lifetime
- 1951-02-24 FR FR1056758D patent/FR1056758A/fr not_active Expired
- 1951-03-03 DE DEI3846A patent/DE852855C/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR1056758A (fr) | 1954-03-02 |
| US2591545A (en) | 1952-04-01 |
| BE501634A (en:Method) | |
| DE852855C (de) | 1952-10-20 |
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