GB516115A - Improvements in or relating to the production of ascorbic acid - Google Patents
Improvements in or relating to the production of ascorbic acidInfo
- Publication number
- GB516115A GB516115A GB17642/38A GB1764238A GB516115A GB 516115 A GB516115 A GB 516115A GB 17642/38 A GB17642/38 A GB 17642/38A GB 1764238 A GB1764238 A GB 1764238A GB 516115 A GB516115 A GB 516115A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- glacial acetic
- laevo
- keto
- hydrochloric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
516,115. Ascorbic acid. STEVENS, A. H. (Pfizer & Co., C.). June 14, 1938, No. 17642. [Class 2 (iii)] Laevo-ascorbic acid is produced by dis-. solving 2-keto-laevo-gulonic acid or a readilyhydrolyzable derivative thereof in glacial acetic acid, concentrated phosphoric acid or - concentrated sulphuric acid, adding at least two gram-equivalents per litre of a non-oxidizing .acid stronger than phosphoric acid, and heating. Suitable non-oxidizing acids are hydrochloric, hydrobromic and sulphuric acids. Sulphuric acid can therefore be used for both functions. After the reaction the mineral acid is removed as soon as possible. When acetic - acid is employed as solvent a considerable amount of esterification occurs, and hydrolysis is therefore effected by boiling with alcohols. In examples (1) 2-keto-laevo-gulonic acid is heated to 90-95‹ C. with glacial acetic acid and hydrochloric acid ; diacetone-2-keto-laevogulonic acid 'is heated with (2) glacial acetic acid and hydrochloric acid ; (3) concentrated sulphuric acid and glacial acetic acid ; and (4) concentrated sulphuric acid. After removal of acid, the ascorbic acid is recrystallized from methyl alcohol. Specification 428,815 is referred to.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB17642/38A GB516115A (en) | 1938-06-14 | 1938-06-14 | Improvements in or relating to the production of ascorbic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB17642/38A GB516115A (en) | 1938-06-14 | 1938-06-14 | Improvements in or relating to the production of ascorbic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB516115A true GB516115A (en) | 1939-12-22 |
Family
ID=10098705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB17642/38A Expired GB516115A (en) | 1938-06-14 | 1938-06-14 | Improvements in or relating to the production of ascorbic acid |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB516115A (en) |
-
1938
- 1938-06-14 GB GB17642/38A patent/GB516115A/en not_active Expired
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