GB500354A - Improvements in the preservation of desiccated biologically active substances in evacuated containers - Google Patents

Improvements in the preservation of desiccated biologically active substances in evacuated containers

Info

Publication number
GB500354A
GB500354A GB1526237A GB1526237A GB500354A GB 500354 A GB500354 A GB 500354A GB 1526237 A GB1526237 A GB 1526237A GB 1526237 A GB1526237 A GB 1526237A GB 500354 A GB500354 A GB 500354A
Authority
GB
Grant status
Application
Patent type
Prior art keywords
stopper
neck
sealed
under vacuum
whilst
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1526237A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp & Dohme Corp
Original Assignee
Merck Sharp & Dohme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00Closing containers or receptacles after filling
    • B65B7/16Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/28Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
    • B65B7/2821Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers applying plugs or threadless stoppers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003Filling medical containers such as ampoules, vials, syringes or the like

Abstract

500,354. Evacuated sealed containers for medical preparations. SHARP & DOHME, Inc. June 1, 1937, No. 15262. Convention date, July 10, 1936. [Class 81. (i)] Desiccated biologically active substances such as sera, bacterial cultures, glandular preparations and the like, and in particular such substances as have been dried whilst frozen, as described in Specification 450,147, are preserved under vacuum in a glass container 10 closed by a perforable self-sealing stopper 14 and having its neck 12 sealed by fusion so as to enclose the stopper. The frozen material 11 is desiccated by the application of vacuum through the neck 12, the vacuum is then released, the stopper 14 inserted, the container re-evacuated through a needle 16 passed through the stopper, and thereafter the neck sealed at 18, preferably whilst the portion of the neck beyond the stopper is under vacuum. In use the sealed neck is broken away and water is introduced from a hypodermic syringe through the stopper 14 so as to make intimate contact with and dissolve the material 11 whilst this is still under vacuum. Specification 500,255 also is referred to.
GB1526237A 1936-07-10 1937-06-01 Improvements in the preservation of desiccated biologically active substances in evacuated containers Expired GB500354A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US500354X true 1936-07-10 1936-07-10

Publications (1)

Publication Number Publication Date
GB500354A true true GB500354A (en) 1939-02-01

Family

ID=21963044

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1526237A Expired GB500354A (en) 1936-07-10 1937-06-01 Improvements in the preservation of desiccated biologically active substances in evacuated containers

Country Status (2)

Country Link
FR (1) FR824186A (en)
GB (1) GB500354A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641004A (en) * 1994-04-26 1997-06-24 Py; Daniel Process for filling a sealed receptacle under aseptic conditions
US7669390B2 (en) 2004-03-08 2010-03-02 Medical Instill Technologies, Inc. Method for molding and assembling containers with stoppers and filling same
US7707807B2 (en) 2004-03-08 2010-05-04 Medical Instill Technologies, Inc. Apparatus for molding and assembling containers with stoppers and filling same
US7779609B2 (en) 2001-10-03 2010-08-24 Medical Instill Technologies, Inc. Method of filling a device
US8071009B2 (en) 2005-10-17 2011-12-06 Medical Instill Technologies, Inc. Sterile de-molding apparatus and method

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641004A (en) * 1994-04-26 1997-06-24 Py; Daniel Process for filling a sealed receptacle under aseptic conditions
US9102097B2 (en) 2000-02-11 2015-08-11 Medinstill Development Llc Resealable member and method of resealing same
US7779609B2 (en) 2001-10-03 2010-08-24 Medical Instill Technologies, Inc. Method of filling a device
US7669390B2 (en) 2004-03-08 2010-03-02 Medical Instill Technologies, Inc. Method for molding and assembling containers with stoppers and filling same
US7975453B2 (en) 2004-03-08 2011-07-12 Medical Instill Technologies, Inc. Apparatus for molding and assembling containers with stoppers and filling same
US8112972B2 (en) 2004-03-08 2012-02-14 Medical Instill Technologies, Inc. Method for molding and assembling containers with stoppers and filling same
US7707807B2 (en) 2004-03-08 2010-05-04 Medical Instill Technologies, Inc. Apparatus for molding and assembling containers with stoppers and filling same
US8071009B2 (en) 2005-10-17 2011-12-06 Medical Instill Technologies, Inc. Sterile de-molding apparatus and method
US8550799B2 (en) 2005-10-17 2013-10-08 Medical Instill Technologies, Inc. Sterile de-molding apparatus and method

Also Published As

Publication number Publication date Type
FR824186A (en) 1938-02-02 grant

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