GB491212A - An improved process for the production of activated gelatin preparations in finely divided form - Google Patents
An improved process for the production of activated gelatin preparations in finely divided formInfo
- Publication number
- GB491212A GB491212A GB556937A GB556937A GB491212A GB 491212 A GB491212 A GB 491212A GB 556937 A GB556937 A GB 556937A GB 556937 A GB556937 A GB 556937A GB 491212 A GB491212 A GB 491212A
- Authority
- GB
- United Kingdom
- Prior art keywords
- gelatine
- water
- oil
- alcohol
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Colloid Chemistry (AREA)
Abstract
A preparation of vitamin A or other food or medicinal substance in gelatine is produced by incorporating the desired substance in aqueous gelatine, emulsifying in an oil which is soluble in an organic water-extracting liquid, causing the gelatine particles to gel, and removing the oil and at least a part of the water by means of the water-extracting liquid. Alternatively the oil may be partly removed by a solvent such as ether, and then the rest of the oil and at least part of the water is removed by the water-extracting agent. Suitable water-extracting liquids are alcohol, acetone, propyl and isopropyl alcohols and dioxane, and suitable oils are castor, soya bean, cottonseed, and mineral oils. Anti-oxidants and sugar and/or glycerine may be added to improve the keeping qualities of the product. In examples: (1) a vitamin A solution or concentrate is incorporated with 40 per cent aqueous glycerine at 65 DEG C., castor oil with or without alcohol is added and a polyphase emulsion is produced and the mixture is cooled to or below 8 DEG C. to cause the gelatine to gel. Alcohol is then added and the mixture is treated in a mortar or jarmill, filtered, and the gelatine particles are washed with alcohol and allowed to stand in alcohol until dehydrated; the particles are finally dried preferably not above 30 DEG C.; (2) vitamin A solution is emulsified at 65 DEG C. in 35 per cent aqueous gelatine containing sugar and glycerine, and the mixture is emulsified with castor oil at 65 DEG C., cooled to gel the gelatine, and the oil and water are extracted with acetone, the particles being dried in an air-chamber. Specification 490,001 is referred to.ALSO:A preparation of vitamin A or other food or medicinal substance in gelatine is produced by incorporating the desired substance in aqueous gelatine, emulsifying in an oil which is soluble in an organic water-extracting liquid, causing the gelatine particles to gel, and removing the oil and at least a part of the water by means of the water-extracting liquid. Alternatively the oil may be partly removed by a solvent such as ether, and then the rest of the oil and at least part of the water is removed by the water-extracting agent. Suitable water-extracting liquids are alcohol, acetone, propyl and isopropyl alcohols and dioxane, and suitable oils are castor, soya bean, cottonseed, and mineral oils. Anti-oxidants and sugar and/or glycerine may be added to improve the keeping qualities of the product. In examples, (1) a vitamin A solution or concentrate is incorporated with 40 per cent aqueous gelatine at 65 DEG C., castor oil with or without alcohol is added, a polyphase emulsion is produced, and the mixture is cooled to or below 8 DEG C. to cause the gelatine to gel. Alcohol is then added and the mixture is treated in a mortar or jar-mill, filtered, and the gelatine particles are washed with alcohol and allowed to stand in alcohol until dehydrated; the particles are finally dried preferably not above 30 DEG C.; (2) vitamin A solution is emulsified at 65 DEG C. in 35 per cent aqueous gelatine containing sugar and glycerine, and the mixture is emulsified with castor oil at 65 DEG C., cooled to gel the gelatine, and the oil and water are extracted with acetone, the particles being dried in an air-chamber. Specification 490,001 is referred to.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB556937A GB491212A (en) | 1937-02-24 | 1937-02-24 | An improved process for the production of activated gelatin preparations in finely divided form |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB556937A GB491212A (en) | 1937-02-24 | 1937-02-24 | An improved process for the production of activated gelatin preparations in finely divided form |
Publications (1)
Publication Number | Publication Date |
---|---|
GB491212A true GB491212A (en) | 1938-08-24 |
Family
ID=9798581
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB556937A Expired GB491212A (en) | 1937-02-24 | 1937-02-24 | An improved process for the production of activated gelatin preparations in finely divided form |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB491212A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020035376A1 (en) * | 2018-08-13 | 2020-02-20 | Unilever Plc | Gel compositions |
-
1937
- 1937-02-24 GB GB556937A patent/GB491212A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020035376A1 (en) * | 2018-08-13 | 2020-02-20 | Unilever Plc | Gel compositions |
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