GB2632086A - Compounds for use in methods for the treatment or prophylaxis of a coronavirus infection or covid 19 - Google Patents
Compounds for use in methods for the treatment or prophylaxis of a coronavirus infection or covid 19 Download PDFInfo
- Publication number
- GB2632086A GB2632086A GB2416046.7A GB202416046A GB2632086A GB 2632086 A GB2632086 A GB 2632086A GB 202416046 A GB202416046 A GB 202416046A GB 2632086 A GB2632086 A GB 2632086A
- Authority
- GB
- United Kingdom
- Prior art keywords
- infection
- compound
- atazanavir
- drug
- sars
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
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- Animal Behavior & Ethology (AREA)
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- Epidemiology (AREA)
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- Emergency Medicine (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Optics & Photonics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063012432P | 2020-04-20 | 2020-04-20 | |
| US202063018768P | 2020-05-01 | 2020-05-01 | |
| US202063032116P | 2020-05-29 | 2020-05-29 | |
| US202063037373P | 2020-06-10 | 2020-06-10 | |
| US202063041812P | 2020-06-19 | 2020-06-19 | |
| US202163170350P | 2021-04-02 | 2021-04-02 | |
| GB2217355.3A GB2613460B (en) | 2020-04-20 | 2021-04-17 | Pharmaceutical Compositions for use in methods for the prophylaxis or treatment of COVID such as COVID-19; and compound for use in the treatment of a |
Publications (2)
| Publication Number | Publication Date |
|---|---|
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| WO2021216385A1 (en) | 2020-04-20 | 2021-10-28 | Tran Lloyd Hung Loi | Methods for the prophylaxis and treatment of covid and covid-19 |
| BR112022022243A2 (pt) * | 2020-05-01 | 2022-12-20 | Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd | Bloqueadores do canal de proteína e e inibidores de orf3 como agentes anti-covid-19. |
| JP2024538711A (ja) * | 2021-10-06 | 2024-10-23 | メディエンス カンパニー リミテッド | エファビレンツ及びフルオキセチンを有効成分として含有するウイルス感染症の予防又は治療用薬学的組成物 |
| EP4427740A4 (en) * | 2021-11-05 | 2025-10-22 | G2Gbio Inc | PHARMACEUTICAL KIT FOR PARENTERAL CO-ADMINISTRATION |
| US20250025473A1 (en) * | 2021-11-12 | 2025-01-23 | Albert Einstein College Of Medicine | Cell impermeable kinase inhibitors to treat sars-cov-2 and/or hsv viral infections |
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| CN111803491A (zh) * | 2020-07-24 | 2020-10-23 | 中国人民解放军军事科学院军事医学研究院 | 青蒿素类化合物在治疗冠状病毒感染方面的应用 |
| CN114246858A (zh) * | 2020-09-21 | 2022-03-29 | 北京化工大学 | 青蒿素类化合物在治疗和预防冠状病毒感染中的应用 |
| GB2613460A (en) * | 2020-04-20 | 2023-06-07 | Lloyd Hung Loi Tran | Methods for the prophylaxis and treatment of Covid and Covid-19 |
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| US7232798B2 (en) | 2001-11-13 | 2007-06-19 | Tran Loi H | Neuroprotection and neuroegenisis by administering cyclic prolyl glycine |
| US7842719B2 (en) * | 2002-10-31 | 2010-11-30 | Kemin Foods, L.C. | Use of endoperoxides for the treatment of infections caused by flaviviridae, including hepatitis C, bovine viral diarrhea and classical swine fever virus |
| EP4368202A3 (en) | 2007-03-30 | 2024-08-21 | The Research Foundation for The State University of New York | Attenuated viruses useful for vaccines |
| AU2008287542C1 (en) * | 2007-06-01 | 2015-01-22 | The Trustees Of Princeton University | Treatment of viral infections by modulation of host cell metabolic pathways |
| CN112423774A (zh) | 2018-05-15 | 2021-02-26 | L·H·L·特兰 | 用于治疗轻度认知障碍、抑郁和心理障碍的治疗剂组成及使用方法 |
| US10980756B1 (en) * | 2020-03-16 | 2021-04-20 | First Wave Bio, Inc. | Methods of treatment |
| WO2021209740A1 (en) * | 2020-04-16 | 2021-10-21 | Mereo Biopharma 4 Limited | Methods involving neutrophil elastase inhibitor alvelestat for treating coronavirus infection |
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| GB2613460A (en) * | 2020-04-20 | 2023-06-07 | Lloyd Hung Loi Tran | Methods for the prophylaxis and treatment of Covid and Covid-19 |
| CN111803491A (zh) * | 2020-07-24 | 2020-10-23 | 中国人民解放军军事科学院军事医学研究院 | 青蒿素类化合物在治疗冠状病毒感染方面的应用 |
| CN114246858A (zh) * | 2020-09-21 | 2022-03-29 | 北京化工大学 | 青蒿素类化合物在治疗和预防冠状病毒感染中的应用 |
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| ACS Infectious Diseases, Vol. 6, No. 9, 31 July 2020, R Cao, "Anti-SARS-CoV-2 Potential of Artemisinins In Vitro, pages 2524-2531 * |
| Journal of Ethnopharmacology, Vol. 274, 5 March 2021, M S Nair, Artemisia annua L. extracts inhibit the in vitro replication of SARS-CoV-2 and two of its variants, 114016 * |
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| WO2021216385A1 (en) | 2021-10-28 |
| US20250319060A1 (en) | 2025-10-16 |
| US12239629B2 (en) | 2025-03-04 |
| JP2023526754A (ja) | 2023-06-23 |
| EP4138906A1 (en) | 2023-03-01 |
| US20230172902A1 (en) | 2023-06-08 |
| GB202416189D0 (en) | 2024-12-18 |
| CA3179317A1 (en) | 2021-10-28 |
| GB2613460A (en) | 2023-06-07 |
| AU2021259185A1 (en) | 2023-01-05 |
| GB202416046D0 (en) | 2024-12-18 |
| BR112022021304A2 (pt) | 2022-12-06 |
| GB202217355D0 (en) | 2023-01-04 |
| GB2613460B (en) | 2025-07-23 |
| EP4138906A4 (en) | 2024-10-30 |
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