GB2460196A - Fluidic methods - Google Patents

Fluidic methods Download PDF

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Publication number
GB2460196A
GB2460196A GB0915119A GB0915119A GB2460196A GB 2460196 A GB2460196 A GB 2460196A GB 0915119 A GB0915119 A GB 0915119A GB 0915119 A GB0915119 A GB 0915119A GB 2460196 A GB2460196 A GB 2460196A
Authority
GB
United Kingdom
Prior art keywords
methods
fluidic methods
fluidic
samples
devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0915119A
Other versions
GB0915119D0 (en
GB2460196B (en
Inventor
Edward K Y Jung
Eric C Leuthardt
Royce A Levien
Robert W Lord
Mark A Malamud
John D Rinaldo Jr
Lowell L Wood Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Searete LLC
Original Assignee
Searete LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/699,747 external-priority patent/US20080181821A1/en
Priority claimed from US11/699,920 external-priority patent/US20080181816A1/en
Priority claimed from US11/699,774 external-priority patent/US20080180259A1/en
Priority claimed from US11/699,770 external-priority patent/US8617903B2/en
Priority claimed from US11/729,275 external-priority patent/US20080241909A1/en
Priority claimed from US11/729,301 external-priority patent/US20080241935A1/en
Priority claimed from US11/729,274 external-priority patent/US20080241000A1/en
Priority claimed from US11/799,462 external-priority patent/US20080178692A1/en
Priority claimed from US11/799,465 external-priority patent/US20080179255A1/en
Application filed by Searete LLC filed Critical Searete LLC
Publication of GB0915119D0 publication Critical patent/GB0915119D0/en
Publication of GB2460196A publication Critical patent/GB2460196A/en
Publication of GB2460196B publication Critical patent/GB2460196B/en
Application granted granted Critical
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/005Pretreatment specially adapted for magnetic separation
    • B03C1/01Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/32Magnetic separation acting on the medium containing the substance being separated, e.g. magneto-gravimetric-, magnetohydrostatic-, or magnetohydrodynamic separation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/12Measuring magnetic properties of articles or specimens of solids or fluids
    • G01R33/1269Measuring magnetic properties of articles or specimens of solids or fluids of molecules labeled with magnetic beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0636Focussing flows, e.g. to laminate flows
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/18Magnetic separation whereby the particles are suspended in a liquid

Abstract

The present disclosure relates to methods and devices that may be used to separate components from one or more samples.
GB0915119A 2007-01-29 2008-01-28 Fluidic methods Expired - Fee Related GB2460196B (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US11/699,774 US20080180259A1 (en) 2007-01-29 2007-01-29 Devices for allergen detection
US11/699,770 US8617903B2 (en) 2007-01-29 2007-01-29 Methods for allergen detection
US11/699,747 US20080181821A1 (en) 2007-01-29 2007-01-29 Microfluidic chips for allergen detection
US11/699,920 US20080181816A1 (en) 2007-01-29 2007-01-29 Systems for allergen detection
US11/729,274 US20080241000A1 (en) 2007-03-27 2007-03-27 Systems for pathogen detection
US11/729,301 US20080241935A1 (en) 2007-03-27 2007-03-27 Methods for pathogen detection
US11/729,276 US20080241910A1 (en) 2007-03-27 2007-03-27 Devices for pathogen detection
US11/729,275 US20080241909A1 (en) 2007-03-27 2007-03-27 Microfluidic chips for pathogen detection
US11/799,462 US20080178692A1 (en) 2007-01-29 2007-04-30 Fluidic methods
US11/799,465 US20080179255A1 (en) 2007-01-29 2007-04-30 Fluidic devices
PCT/US2008/001255 WO2008094620A2 (en) 2007-01-29 2008-01-28 Fluidic methods

Publications (3)

Publication Number Publication Date
GB0915119D0 GB0915119D0 (en) 2009-10-07
GB2460196A true GB2460196A (en) 2009-11-25
GB2460196B GB2460196B (en) 2011-06-01

Family

ID=39674716

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0915119A Expired - Fee Related GB2460196B (en) 2007-01-29 2008-01-28 Fluidic methods

Country Status (2)

Country Link
GB (1) GB2460196B (en)
WO (1) WO2008094620A2 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922210A (en) * 1995-06-16 1999-07-13 University Of Washington Tangential flow planar microfabricated fluid filter and method of using thereof
US6221677B1 (en) * 1997-09-26 2001-04-24 University Of Washington Simultaneous particle separation and chemical reaction
US6408884B1 (en) * 1999-12-15 2002-06-25 University Of Washington Magnetically actuated fluid handling devices for microfluidic applications
US6541213B1 (en) * 1996-03-29 2003-04-01 University Of Washington Microscale diffusion immunoassay
US6716642B1 (en) * 1999-03-15 2004-04-06 Aviva Biosciences Corporation Individually addressable micro-electromagnetic unit array chips in horizontal configurations
US6877892B2 (en) * 2002-01-11 2005-04-12 Nanostream, Inc. Multi-stream microfluidic aperture mixers

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922210A (en) * 1995-06-16 1999-07-13 University Of Washington Tangential flow planar microfabricated fluid filter and method of using thereof
US6541213B1 (en) * 1996-03-29 2003-04-01 University Of Washington Microscale diffusion immunoassay
US6221677B1 (en) * 1997-09-26 2001-04-24 University Of Washington Simultaneous particle separation and chemical reaction
US6716642B1 (en) * 1999-03-15 2004-04-06 Aviva Biosciences Corporation Individually addressable micro-electromagnetic unit array chips in horizontal configurations
US6408884B1 (en) * 1999-12-15 2002-06-25 University Of Washington Magnetically actuated fluid handling devices for microfluidic applications
US6877892B2 (en) * 2002-01-11 2005-04-12 Nanostream, Inc. Multi-stream microfluidic aperture mixers

Also Published As

Publication number Publication date
WO2008094620A2 (en) 2008-08-07
GB0915119D0 (en) 2009-10-07
WO2008094620A3 (en) 2009-01-15
GB2460196B (en) 2011-06-01

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Free format text: REGISTERED BETWEEN 20141120 AND 20141126

732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)

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732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)

Free format text: REGISTERED BETWEEN 20201015 AND 20201021

PCNP Patent ceased through non-payment of renewal fee

Effective date: 20230128