GB2456998A - Device and method for producing therapeutic foam - Google Patents

Device and method for producing therapeutic foam Download PDF

Info

Publication number
GB2456998A
GB2456998A GB0910182A GB0910182A GB2456998A GB 2456998 A GB2456998 A GB 2456998A GB 0910182 A GB0910182 A GB 0910182A GB 0910182 A GB0910182 A GB 0910182A GB 2456998 A GB2456998 A GB 2456998A
Authority
GB
United Kingdom
Prior art keywords
foam
chamber
loop
mesh
producing therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0910182A
Other versions
GB2456998B (en
GB0910182D0 (en
Inventor
David Dakin Iorwerth Wright
Anthony David Harman
Garry Hodges
David Targell
Mark Simpson Yeoman
Jeremy Francis Donnan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
BTG International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0625649A external-priority patent/GB0625649D0/en
Priority claimed from EP06026562A external-priority patent/EP1935605A1/en
Application filed by BTG International Ltd filed Critical BTG International Ltd
Publication of GB0910182D0 publication Critical patent/GB0910182D0/en
Publication of GB2456998A publication Critical patent/GB2456998A/en
Application granted granted Critical
Publication of GB2456998B publication Critical patent/GB2456998B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B7/00—Mixing; Kneading
    • B29B7/74—Mixing; Kneading using other mixers or combinations of mixers, e.g. of dissimilar mixers ; Plant
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C44/00—Shaping by internal pressure generated in the material, e.g. swelling or foaming ; Producing porous or cellular expanded plastics articles
    • B29C44/34—Auxiliary operations
    • B29C44/3442—Mixing, kneading or conveying the foamable material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/235—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids for making foam
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/50—Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle
    • B01F25/51—Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle in which the mixture is circulated through a set of tubes, e.g. with gradual introduction of a component into the circulating flow
    • B01F3/04446—
    • B01F5/102—
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B7/00—Mixing; Kneading
    • B29B7/74—Mixing; Kneading using other mixers or combinations of mixers, e.g. of dissimilar mixers ; Plant
    • B29B7/7404—Mixing devices specially adapted for foamable substances
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B7/00—Mixing; Kneading
    • B29B7/74—Mixing; Kneading using other mixers or combinations of mixers, e.g. of dissimilar mixers ; Plant
    • B29B7/7404—Mixing devices specially adapted for foamable substances
    • B29B7/7409—Mixing devices specially adapted for foamable substances with supply of gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams

Abstract

A device and a method for generating therapeutic foam from a sclerosing solution such as polidocanol and a gas which is absorbable or dissolvable in the body comprises a disposable cassette including a liquid container and a flexible chamber containing gas, chamber being formed as a loop (6). Located in the loop chamber (6) is a foam generating mesh (8). In use, liquid is introduced into the chamber and then the cassette is inserted into a pumping machine where it is engaged by a peristaltic pump which circulates the contents of the loop chamber (6) through the mesh (8), thus creating foam. When a steady state is reached, foam may be withdrawn using a syringe via either a port (3) or septum.
GB0910182A 2006-12-21 2007-12-21 Method and apparatus for producing foam Active GB2456998B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0625649A GB0625649D0 (en) 2006-12-21 2006-12-21 Method and apparatus for producing foam
EP06026562A EP1935605A1 (en) 2006-12-21 2006-12-21 Method and apparatus for producing foam
PCT/GB2007/004943 WO2008075080A1 (en) 2006-12-21 2007-12-21 Device and method for producing therapeutic foam

Publications (3)

Publication Number Publication Date
GB0910182D0 GB0910182D0 (en) 2009-07-29
GB2456998A true GB2456998A (en) 2009-08-05
GB2456998B GB2456998B (en) 2011-09-28

Family

ID=39204700

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0910182A Active GB2456998B (en) 2006-12-21 2007-12-21 Method and apparatus for producing foam

Country Status (17)

Country Link
US (2) US8235935B2 (en)
EP (2) EP2125322B1 (en)
JP (1) JP5069753B2 (en)
KR (1) KR101547610B1 (en)
CN (1) CN102950695B (en)
AU (1) AU2007336023B2 (en)
CA (1) CA2672834C (en)
CY (1) CY1114009T1 (en)
DE (1) DE112007003084T5 (en)
DK (1) DK2125322T3 (en)
ES (1) ES2402904T3 (en)
GB (1) GB2456998B (en)
HK (2) HK1137164A1 (en)
PL (1) PL2125322T3 (en)
PT (1) PT2125322E (en)
SI (1) SI2125322T1 (en)
WO (1) WO2008075080A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1436029A4 (en) * 2001-09-24 2009-12-30 Scott Lab Inc Methods and apparatuses for assuring quality and safety of drug administration and medical products and kits
US9526846B2 (en) 2009-08-19 2016-12-27 Safety Syringes, Inc. Patient-contact activated needle stick safety device
CN101870153B (en) * 2010-06-22 2012-12-19 青岛鑫三利冷箱技术有限公司 Refrigerated container insulating layer small-area outdoor foaming preheating holding device
US9861736B2 (en) * 2013-05-31 2018-01-09 Fenwal, Inc. Methods for extracting platelet-rich plasma for therapeutic injection
EP2962681A1 (en) * 2014-07-03 2016-01-06 Swiss VX Venentherapie und Forschung GmbH Devices and methods for injectable vascular sclerofoams using a carrier made of human blood and uses thereof
EP3170549A1 (en) * 2015-11-17 2017-05-24 Enrique Roche Rebollo Methods, devices, systems and kits for preparing compositions for care and repair of varicose veins
GB201611778D0 (en) * 2016-07-06 2016-08-17 Provensis Ltd Method and device for producing foam
GB201612925D0 (en) * 2016-07-26 2016-09-07 Provensis Ltd Method and device for generating injectable foam
FR3067910B1 (en) * 2017-06-23 2021-06-18 Seb Sa APPARATUS FOR MANUFACTURING A PERSONALIZED COSMETIC PRODUCT
WO2019241014A1 (en) 2018-06-14 2019-12-19 Curium Us Llc Evacuation/fill station for radioactive fluid container production
CN112584919B (en) * 2018-08-21 2023-08-25 巴塞罗那血管设备有限责任公司 Preparation method, device, system and kit of varicose vein repair composition
CN112454710B (en) * 2020-11-28 2022-06-10 深圳海源恒业高新材料科技研发有限公司 Rubber banburying processing equipment based on green

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1589306A (en) * 1978-05-24 1981-05-13 Grace W R Ltd Method and apparatus for mixing polyurethane foam
EP0091312A2 (en) * 1982-04-06 1983-10-12 Baxter Travenol Laboratories, Inc. Apparatus and method for mixing separately stored components
EP1647255A2 (en) * 2004-10-13 2006-04-19 Pentaferte Spa Method for preparing sclerosing foams and medical device for implementing said method
WO2006120461A1 (en) * 2005-05-13 2006-11-16 Btg International Limited Preparation of therapeutic foam

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57206447A (en) * 1981-06-12 1982-12-17 Terumo Corp Plastic container receiving liquid drug pasturized with high pressure steam and production thereof
EP0082465A1 (en) * 1981-12-23 1983-06-29 Ramisch Kleinewefers GmbH Apparatus for feeding foam to a coating device
US5174285A (en) * 1990-01-08 1992-12-29 Lake Shore Medical Development Partners Ltd. Localized heat transfer device
CN2075540U (en) * 1990-08-04 1991-04-24 周长根 Foam jet vertical generating device
US5066428A (en) * 1990-08-08 1991-11-19 Rusmar Incorporated Foam generating apparatus
CN1023881C (en) * 1991-10-24 1994-03-02 苏彦 Bubble generator and its use
ES2068151B1 (en) 1993-06-23 1995-11-16 Cabrera Garrido Juan INJECTABLE MICROS FOAM FOR SCLEROSIS.
GB9912356D0 (en) 1999-05-26 1999-07-28 Btg Int Ltd Generation of microfoam
US6547063B1 (en) 2000-10-10 2003-04-15 The Procter & Gamble Company Article for the delivery of foam products
EP1266682B1 (en) 2001-06-11 2004-01-28 Filtertek B.V. Combination filter device
GB0300586D0 (en) 2003-01-10 2003-02-12 Btg Int Ltd Therapeutic microfoam
PL223344B1 (en) 2003-11-17 2016-10-31 Btg Int Ltd Therapeutic foam
GB0327957D0 (en) * 2003-12-03 2004-01-07 Btg Int Ltd Apparatus for delivering foam
EP1814650A1 (en) 2004-10-29 2007-08-08 Koninklijke Philips Electronics N.V. Apparatus and method for the production of ultrasound contrasts agents
GB0509819D0 (en) 2005-05-13 2005-06-22 Btg Int Ltd Therapeutic foam
EP1901712B1 (en) 2005-05-13 2012-06-20 BTG International Limited Therapeutic sclerosing foam made preferably from xenon
JP5587531B2 (en) * 2007-07-19 2014-09-10 ノードソン コーポレーション Slot nozzle assembly, slot coat gun, and method for extruding foamable melt into wide strip

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1589306A (en) * 1978-05-24 1981-05-13 Grace W R Ltd Method and apparatus for mixing polyurethane foam
EP0091312A2 (en) * 1982-04-06 1983-10-12 Baxter Travenol Laboratories, Inc. Apparatus and method for mixing separately stored components
EP1647255A2 (en) * 2004-10-13 2006-04-19 Pentaferte Spa Method for preparing sclerosing foams and medical device for implementing said method
WO2006120461A1 (en) * 2005-05-13 2006-11-16 Btg International Limited Preparation of therapeutic foam

Also Published As

Publication number Publication date
US8235935B2 (en) 2012-08-07
GB2456998B (en) 2011-09-28
EP2452797A2 (en) 2012-05-16
PT2125322E (en) 2013-06-04
GB0910182D0 (en) 2009-07-29
ES2402904T3 (en) 2013-05-10
EP2452797A3 (en) 2013-10-09
KR101547610B1 (en) 2015-08-26
CN102950695A (en) 2013-03-06
JP2010512899A (en) 2010-04-30
JP5069753B2 (en) 2012-11-07
PL2125322T3 (en) 2013-08-30
US20120273977A1 (en) 2012-11-01
CY1114009T1 (en) 2016-07-27
DK2125322T3 (en) 2013-04-02
AU2007336023B2 (en) 2013-07-04
CN102950695B (en) 2015-05-27
US20100099778A1 (en) 2010-04-22
KR20090102820A (en) 2009-09-30
WO2008075080A1 (en) 2008-06-26
CA2672834C (en) 2015-04-21
HK1182994A1 (en) 2013-12-13
HK1137164A1 (en) 2010-07-23
EP2125322B1 (en) 2013-03-06
EP2125322A1 (en) 2009-12-02
DE112007003084T5 (en) 2009-10-29
AU2007336023A1 (en) 2008-06-26
US8517975B2 (en) 2013-08-27
SI2125322T1 (en) 2013-07-31
CA2672834A1 (en) 2008-06-26

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