GB2418921A - Antimicrobial polymers - Google Patents

Antimicrobial polymers Download PDF

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Publication number
GB2418921A
GB2418921A GB0602026A GB0602026A GB2418921A GB 2418921 A GB2418921 A GB 2418921A GB 0602026 A GB0602026 A GB 0602026A GB 0602026 A GB0602026 A GB 0602026A GB 2418921 A GB2418921 A GB 2418921A
Authority
GB
United Kingdom
Prior art keywords
present
production
antimicrobial
antimicrobial polymers
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0602026A
Other versions
GB2418921B (en
GB0602026D0 (en
Inventor
Robert Engel
Jaimelee Iolani Cohen
Karin Melkonian
Paul William Watt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethicon Inc
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Publication of GB0602026D0 publication Critical patent/GB0602026D0/en
Publication of GB2418921A publication Critical patent/GB2418921A/en
Application granted granted Critical
Publication of GB2418921B publication Critical patent/GB2418921B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02Amines; Quaternary ammonium compounds
    • A01N33/12Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • A01N43/32Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms six-membered rings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/34Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-halogen bonds; Phosphonium salts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/36Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus as a ring member
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/02Sulfur; Selenium; Tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/46Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00Preparation of cellulose ethers
    • C08B11/02Alkyl or cycloalkyl ethers
    • C08B11/04Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
    • C08B11/10Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals substituted with acid radicals
    • C08B11/12Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals substituted with acid radicals substituted with carboxylic radicals, e.g. carboxymethylcellulose [CMC]
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10Esters
    • C08F220/34Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/14Esterification
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/44Preparation of metal salts or ammonium salts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A61L2300/208Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents

Abstract

The present invention is concerned with providing antimicrobial compounds and processes for the production thereof More particularly, the present invention provides antimicrobial polymeric materials comprising a polymer linked to a positively charged moiety via a carboxyl group. The present invention also provides processes for the production of such antimicrobial compounds and uses therefor.

Description

GB 2418921 A continuation (72) Inventor(s): (56) cont Robert Engel
Macromolecular Symposia, February 2003, J JaimeLee lolani Cohen Lukaszczyk et al, "Synthesis and evaluation of Ka fin M elkonian cat ion ic and cat ionogenic polymeric sorbents for Paul William Watt removing surfactants from aqueous solutions", pages 247-256.
(74) Agent and/or Address for Service:
Carpmaels & Ransford (58) Field of Search by ISA:
43 Bloomsbury Square, LONDON, INTCLA01N, A61K, A61L, C08B, C08F WC1A ERA, United Kingdom Other: EPO-lnternal, CHEM ABS Data, PAJ, WPI Data, INSPEC, BIOSIS, COMPINDEX
GB0602026A 2003-08-12 2004-08-12 Antimicrobial polymers Expired - Fee Related GB2418921B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0318896A GB2404920A (en) 2003-08-12 2003-08-12 Antimicrobial polymer
PCT/GB2004/003465 WO2005016972A1 (en) 2003-08-12 2004-08-12 Antimicrobial polymers

Publications (3)

Publication Number Publication Date
GB0602026D0 GB0602026D0 (en) 2006-03-15
GB2418921A true GB2418921A (en) 2006-04-12
GB2418921B GB2418921B (en) 2008-03-12

Family

ID=28052355

Family Applications (2)

Application Number Title Priority Date Filing Date
GB0318896A Withdrawn GB2404920A (en) 2003-08-12 2003-08-12 Antimicrobial polymer
GB0602026A Expired - Fee Related GB2418921B (en) 2003-08-12 2004-08-12 Antimicrobial polymers

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB0318896A Withdrawn GB2404920A (en) 2003-08-12 2003-08-12 Antimicrobial polymer

Country Status (3)

Country Link
US (1) US20080269451A1 (en)
GB (2) GB2404920A (en)
WO (1) WO2005016972A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2433263A (en) * 2005-12-15 2007-06-20 Ethicon Inc Antimicrobial polyurethane foam
KR20090087867A (en) * 2006-08-30 2009-08-18 리서치 파운데이션 오브 더 시티 유니버시티 오브 뉴욕 Antimicrobial compositions
US7919480B2 (en) 2007-05-03 2011-04-05 Ethicon, Inc. Polymers having covalently bound antibiotic agents
JP2010529228A (en) 2007-05-30 2010-08-26 リサーチ・ファウンデーション・オブ・ザ・シティー・ユニヴァーシティー・オブ・ニュー・ヨーク Embedding antibiotics in solid polymers
WO2011075734A2 (en) * 2009-12-18 2011-06-23 Research Foundation Of The City University Of New York Manufacture of antimicrobial nylon, poly(meth)acrylates, and poly(meth)acrylamides
CN102010482A (en) * 2010-11-02 2011-04-13 中国农业科学院农业环境与可持续发展研究所 Method for preparing super-strong water-absorbing water-retaining agent
CN103044612B (en) * 2012-10-26 2014-12-10 华南农业大学 Organic nano antibacterial agent containing N<+1> as well as preparation method and application of organic nano antibacterial agent
GB201301618D0 (en) * 2013-01-30 2013-03-13 Ge Healthcare Uk Ltd Solid medium for the storage of Biological Material
US20150209386A1 (en) * 2014-10-24 2015-07-30 The Cupron Corporation Copper Containing Materials for Treating Wounds, Burns and Other Skin Conditions
CN106084133B (en) * 2016-06-15 2018-09-14 东北林业大学 A kind of synthetic method of biocidal property high hydroscopic resin
EP3551159A4 (en) * 2016-10-17 2020-06-03 Medcura, Inc. Materials comprising hydrophobically-modified biopolymer
US20210077249A1 (en) * 2018-01-31 2021-03-18 KeraMed, Inc. Antimicrobial Polymer for Use in Ophthalmic implants

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WO2003086477A2 (en) * 2002-04-05 2003-10-23 Research Foundation Of The City University Of New York Antimicrobial surfaces
EP1430915A1 (en) * 2002-12-19 2004-06-23 Ethicon, Inc. Cationic alkyd polyesters for medical applications

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US6114484A (en) * 1998-11-16 2000-09-05 Nalco Chemical Company Polymers for chemical treatment and precipitation of soluble metal cyanide and oxoanion compounds from waste water
WO2003086477A2 (en) * 2002-04-05 2003-10-23 Research Foundation Of The City University Of New York Antimicrobial surfaces
EP1430915A1 (en) * 2002-12-19 2004-06-23 Ethicon, Inc. Cationic alkyd polyesters for medical applications

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Carbohydrate Polymers Vol. 52, No. 1, April 2003, H Ronghua et al, "Preparation and in vitro anticoagulant and its quarterized derivatives", pages 19-24. *
Carbohydrate Research Vol. 337, 2002, T Abel et al, "Preparation and investigation of antibacterial carbohydrate-based surfaces". *
Macromolecular Symposia, February 2003, J Lukaszczyk et al, "Synthesis and evaluation of cationic and cationogenic polymeric sorbents for removing surfactants from aqueous solutions", pages 247-256. *
Polymers for Advanced Technologies Vol. 11, No. 8-12, August 2000, A Magnani et al, "Novel polysaccharide hydrogels: characterization and properties", pages 488-495. *

Also Published As

Publication number Publication date
WO2005016972A1 (en) 2005-02-24
GB2418921B (en) 2008-03-12
US20080269451A1 (en) 2008-10-30
GB0602026D0 (en) 2006-03-15
GB0318896D0 (en) 2003-09-17
GB2404920A (en) 2005-02-16

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Effective date: 20120812

732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)

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