GB2407814A - Clopidogrel - Google Patents

Clopidogrel Download PDF

Info

Publication number
GB2407814A
GB2407814A GB0504151A GB0504151A GB2407814A GB 2407814 A GB2407814 A GB 2407814A GB 0504151 A GB0504151 A GB 0504151A GB 0504151 A GB0504151 A GB 0504151A GB 2407814 A GB2407814 A GB 2407814A
Authority
GB
United Kingdom
Prior art keywords
clopidogrel
pharmaceutically acceptable
acceptable salt
amorphous form
wc1v
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB0504151A
Other versions
GB0504151D0 (en
Inventor
Dharmaraj Ramachandra Rao
Rajendra Narayanrao Kankan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cipla Ltd
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd filed Critical Cipla Ltd
Publication of GB0504151D0 publication Critical patent/GB0504151D0/en
Publication of GB2407814A publication Critical patent/GB2407814A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Clopidogrel, or a pharmaceutically acceptable salt thereof in an amorphous form.

Description

GB 2407814 A continuation (74) Agent and/or Address for Service: A A
Thornton & Co 235 High Holborn, LONDON, WC1V 7LE, United Kingdom
GB0504151A 2002-09-19 2003-09-16 Clopidogrel Withdrawn GB2407814A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0221788A GB2393181A (en) 2002-09-19 2002-09-19 Amorphous clopidogrel
PCT/GB2003/003988 WO2004026879A1 (en) 2002-09-19 2003-09-16 Clopidogrel

Publications (2)

Publication Number Publication Date
GB0504151D0 GB0504151D0 (en) 2005-04-06
GB2407814A true GB2407814A (en) 2005-05-11

Family

ID=9944408

Family Applications (2)

Application Number Title Priority Date Filing Date
GB0221788A Withdrawn GB2393181A (en) 2002-09-19 2002-09-19 Amorphous clopidogrel
GB0504151A Withdrawn GB2407814A (en) 2002-09-19 2003-09-16 Clopidogrel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB0221788A Withdrawn GB2393181A (en) 2002-09-19 2002-09-19 Amorphous clopidogrel

Country Status (6)

Country Link
KR (1) KR20050071495A (en)
AU (1) AU2003269140A1 (en)
DE (1) DE10393290T5 (en)
GB (2) GB2393181A (en)
RU (1) RU2005110917A (en)
WO (1) WO2004026879A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005070464A2 (en) * 2004-01-21 2005-08-04 Biofarma Ilac Sanayi Ve Ticaret A.S. A tablet formulation of clopidogrel bisulphate
BRPI0418726A (en) * 2004-04-09 2007-09-11 Hanmi Pharm Ind Co Ltd crystalline clopidogrel naphthalenesulfonate or hydrate thereof, method for their preparation and pharmaceutical composition containing the same
WO2005117866A1 (en) * 2004-06-01 2005-12-15 Ivax Pharmaceuticals S.R.O. Amorphous clopidogrel hydrochloride and its antithrombotic use
GB0418580D0 (en) * 2004-08-21 2004-09-22 Ivax Pharmaceuticals Sro Clopidogrel salt
WO2006074066A1 (en) * 2004-12-30 2006-07-13 Nektar Therapeutics Non-crystalline formulation comprising clopidogrel
KR20070009851A (en) * 2005-07-14 2007-01-19 씨제이 주식회사 Pharmaceutical compositions containing clopidogrel bisulfate
DE102005060690B4 (en) * 2005-12-15 2008-09-25 Capsulution Nanoscience Ag Salts of clopidogrel with polyanions and their use in the preparation of pharmaceutical formulations
JP2009532462A (en) * 2006-04-05 2009-09-10 カディラ・ヘルスケア・リミテッド Modified release clopidogrel formulation
SI22383A (en) * 2006-09-22 2008-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto New procedure of synthesis of klopidogrel and new form of its pharmaceutically acceptable salts
EP1970054A3 (en) * 2007-03-14 2009-06-03 Ranbaxy Laboratories Limited Clopidogrel tablets
ATE530172T1 (en) 2008-02-26 2011-11-15 Lesvi Laboratorios Sl PHARMACEUTICAL FORMULATIONS CONTAINING CLOPIDOGREL
EP2107061A1 (en) 2008-04-02 2009-10-07 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of optically enriched clopidogrel
CN102358743A (en) * 2011-11-05 2012-02-22 江南大学 Simple method for preparing amorphous clopidogrel hydrosulphate
CN102443010A (en) * 2011-11-05 2012-05-09 江南大学 Method for preparing amorphous clopidogrel hydrogen sulfate
HUP1400294A2 (en) 2014-06-13 2015-12-28 Skillpharm Kft Novel application of clopidogrel
CN105218559A (en) * 2015-10-21 2016-01-06 云南省药物研究所 A kind of stable non-crystalline state bisulfate clopidogrel mixture

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284277B1 (en) * 1995-11-03 2001-09-04 Sanofi-Synthelabo Stable freeze-dried pharmaceutical formulation
WO2003051362A2 (en) * 2001-12-18 2003-06-26 Teva Pharmaceutical Industries Ltd. Polymorphs of clopidogrel hydrogensulfate

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284277B1 (en) * 1995-11-03 2001-09-04 Sanofi-Synthelabo Stable freeze-dried pharmaceutical formulation
WO2003051362A2 (en) * 2001-12-18 2003-06-26 Teva Pharmaceutical Industries Ltd. Polymorphs of clopidogrel hydrogensulfate

Also Published As

Publication number Publication date
KR20050071495A (en) 2005-07-07
GB2393181A (en) 2004-03-24
GB0504151D0 (en) 2005-04-06
RU2005110917A (en) 2006-01-20
AU2003269140A1 (en) 2004-04-08
DE10393290T5 (en) 2005-09-29
WO2004026879A1 (en) 2004-04-01
GB0221788D0 (en) 2002-10-30

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)