GB2362105A - Aciclovir compositions containing dimethicone - Google Patents

Aciclovir compositions containing dimethicone

Info

Publication number
GB2362105A
GB2362105A GB0117795A GB0117795A GB2362105A GB 2362105 A GB2362105 A GB 2362105A GB 0117795 A GB0117795 A GB 0117795A GB 0117795 A GB0117795 A GB 0117795A GB 2362105 A GB2362105 A GB 2362105A
Authority
GB
United Kingdom
Prior art keywords
aciclovir
compositions containing
water
containing dimethicone
dimethicone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0117795A
Other versions
GB0117795D0 (en
GB2362105B (en
Inventor
Parbinder Singh Cheema
David Gower
Andrew David Mounter
Timothy Giles Sabey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10845017&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB2362105(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of GB0117795D0 publication Critical patent/GB0117795D0/en
Publication of GB2362105A publication Critical patent/GB2362105A/en
Application granted granted Critical
Publication of GB2362105B publication Critical patent/GB2362105B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Abstract

There is provided an oil-in-water topical pharmaceutical formulation comprising a continuous aqueous phase comprising water, solubilised aciclovir and at least 30 % by weight of a water miscible polyhydric alcohol, with a dispersed oil phase and dimethicone.
GB0117795A 1998-12-23 1999-12-21 Aciclovir compositions containing dimethicone Expired - Lifetime GB2362105B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9828620.6A GB9828620D0 (en) 1998-12-23 1998-12-23 Medicaments
PCT/EP1999/010155 WO2000038695A2 (en) 1998-12-23 1999-12-21 Aciclovir compositions containing dimethicone

Publications (3)

Publication Number Publication Date
GB0117795D0 GB0117795D0 (en) 2001-09-12
GB2362105A true GB2362105A (en) 2001-11-14
GB2362105B GB2362105B (en) 2003-06-18

Family

ID=10845017

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB9828620.6A Ceased GB9828620D0 (en) 1998-12-23 1998-12-23 Medicaments
GB0117795A Expired - Lifetime GB2362105B (en) 1998-12-23 1999-12-21 Aciclovir compositions containing dimethicone

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB9828620.6A Ceased GB9828620D0 (en) 1998-12-23 1998-12-23 Medicaments

Country Status (27)

Country Link
EP (1) EP1140117B1 (en)
JP (1) JP4145493B2 (en)
KR (1) KR100707329B1 (en)
CN (2) CN100415237C (en)
AR (1) AR021993A1 (en)
AT (1) ATE236644T1 (en)
AU (1) AU768989B2 (en)
BR (1) BR9916524A (en)
CA (1) CA2356895A1 (en)
CZ (1) CZ295770B6 (en)
DE (2) DE29924428U1 (en)
DK (1) DK1140117T3 (en)
ES (1) ES2196910T3 (en)
GB (2) GB9828620D0 (en)
HK (2) HK1039275A1 (en)
HU (1) HU230542B1 (en)
IL (2) IL143833A0 (en)
NO (1) NO322090B1 (en)
NZ (1) NZ512457A (en)
PE (1) PE20001351A1 (en)
PL (1) PL196629B1 (en)
PT (1) PT1140117E (en)
SI (1) SI1140117T1 (en)
TR (1) TR200102482T2 (en)
TW (1) TW585768B (en)
WO (1) WO2000038695A2 (en)
ZA (1) ZA200105071B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2005824A1 (en) † 2007-06-21 2008-12-24 Bayer CropScience AG Active agent suspensions in glycerine
BRPI0914454A2 (en) * 2008-10-21 2015-10-27 Novodermix Internat Ltd "composition for the treatment of epithelial tissue"
EP2672956A1 (en) * 2011-02-10 2013-12-18 Moberg Pharma AB Novel formulations for dermal, transdermal and mucosal use 1
WO2015082172A1 (en) * 2013-12-03 2015-06-11 Zzip Ag Polydimethylsiloxane for the treatment of viral infections

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044543A1 (en) * 1980-07-18 1982-01-27 The Wellcome Foundation Limited Topical formulations of 9-(2-hydroxyethoxymethyl) guanine
EP0394928A1 (en) * 1989-04-24 1990-10-31 Syntex (U.S.A.) Inc. Topical antiviral pharmaceutical composition containing a nonionic surfactant
WO1993000905A1 (en) * 1991-07-11 1993-01-21 Smithkline Beecham Plc Tropical composition containing penciclovir
EP0719540A1 (en) * 1994-12-15 1996-07-03 Centre International De Recherches Dermatologiques Galderma (C.I.R.D. Galderma) Cosmetic or dermatological water-in-oil emulsion with high hydroxyacids content
EP0755675A1 (en) * 1995-07-28 1997-01-29 L'oreal Dermatological and/or pharmaceutical composition, process of preparation and utilization

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044543A1 (en) * 1980-07-18 1982-01-27 The Wellcome Foundation Limited Topical formulations of 9-(2-hydroxyethoxymethyl) guanine
EP0394928A1 (en) * 1989-04-24 1990-10-31 Syntex (U.S.A.) Inc. Topical antiviral pharmaceutical composition containing a nonionic surfactant
WO1993000905A1 (en) * 1991-07-11 1993-01-21 Smithkline Beecham Plc Tropical composition containing penciclovir
EP0719540A1 (en) * 1994-12-15 1996-07-03 Centre International De Recherches Dermatologiques Galderma (C.I.R.D. Galderma) Cosmetic or dermatological water-in-oil emulsion with high hydroxyacids content
EP0755675A1 (en) * 1995-07-28 1997-01-29 L'oreal Dermatological and/or pharmaceutical composition, process of preparation and utilization

Also Published As

Publication number Publication date
AR021993A1 (en) 2002-09-04
CN1334737A (en) 2002-02-06
CN1191834C (en) 2005-03-09
KR20010099932A (en) 2001-11-09
EP1140117B1 (en) 2003-04-09
GB9828620D0 (en) 1999-02-17
PL196629B1 (en) 2008-01-31
PT1140117E (en) 2003-08-29
NO322090B1 (en) 2006-08-14
DK1140117T3 (en) 2003-07-21
DE29924428U1 (en) 2003-08-28
CA2356895A1 (en) 2000-07-06
HUP0104594A2 (en) 2002-06-29
IL143833A0 (en) 2002-04-21
HK1067548A1 (en) 2005-04-15
PL349505A1 (en) 2002-07-29
JP2002542149A (en) 2002-12-10
SI1140117T1 (en) 2003-12-31
AU768989B2 (en) 2004-01-15
KR100707329B1 (en) 2007-04-13
NZ512457A (en) 2003-10-31
NO20013103L (en) 2001-08-20
CN100415237C (en) 2008-09-03
TR200102482T2 (en) 2003-03-21
NO20013103D0 (en) 2001-06-21
EP1140117A2 (en) 2001-10-10
IL143833A (en) 2006-12-31
AU2099700A (en) 2000-07-31
DE69906796D1 (en) 2003-05-15
BR9916524A (en) 2001-10-02
GB0117795D0 (en) 2001-09-12
ATE236644T1 (en) 2003-04-15
HU230542B1 (en) 2016-11-28
ES2196910T3 (en) 2003-12-16
TW585768B (en) 2004-05-01
CZ20012332A3 (en) 2001-12-12
CN1539421A (en) 2004-10-27
JP4145493B2 (en) 2008-09-03
WO2000038695A3 (en) 2000-10-26
HK1039275A1 (en) 2002-04-19
CZ295770B6 (en) 2005-11-16
GB2362105B (en) 2003-06-18
DE69906796T2 (en) 2004-01-29
WO2000038695A2 (en) 2000-07-06
HUP0104594A3 (en) 2002-12-28
PE20001351A1 (en) 2000-12-14
ZA200105071B (en) 2002-09-20

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Expiry date: 20191220