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Creams useful for treating psoriasis,exzema and lichen planus

Abstract

Topical applied creams for alleviating chronic skin disorders comprise mixtures of hydrolysed Ghee (butterfat) and extracts from Trifla, Terminalia chebula and belerica, Phyllanthus embelica, Melia azadirecta and Tenospora cordifolia.

Classifications

A61Q17/00 Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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GB2274058A

United Kingdom

Inventor
Eladevi Shah
Current Assignee
Individual

Worldwide applications
1992 GB GB

Application GB9224754A events
1997-06-25
Application granted
Anticipated expiration
Expired - Fee Related

Description

INNOVATION BASED ON HERBAL COMPOSITIONS These innovative products are going to be effective cure for chronic skin disorders and also for many stress related problems.
This invention is potentially powerful in diminishing the severity of the immunae response and it also maintains the achieved healthy status for quite a longer period without any side effects.
The composition provides an antihistaminic agent, an adrenocortical stimulant a cortisol protecting agent and an anti-inflammatory agent.
So, it breaks the cycle of pruritus - inflammation and inflammation - pruritus and results into faster healing of chronic skin problems like psoriasis, eczema and lichen planus.
Creams are made lanolin free. GHEE is used for the preparation of creams. GHEE is a totally fat product of dairy.
EtioPathology of Eczema and Psoriasis According to Ayurvedic science the very first cause of eczema and psoriasis is impurity of blood. Here impurity of bloods means altered immunae response and imbalance of adrenocortical axis and may be antigen antibody reaction.
It is also explained that "Virudha Aahar Vihar" it means the types of food which cannot go together if eaten by negligency. "Vihar" means life style (disturbed sleep, late nights, lead their life with irritated mood).
"Asat Aachar Vicar it means wrong deeds and wrong thoughts.
This herbal composition is meant for physical and mental wellbeing of the patients.
In the books of Ayurveda in all eighteen different types of acute and chronic skin conditions are described which include erysepalas, cellulitis, leucoderma, neurodermat it is, weeping eczema, lichenified eczema, psoriasis, lupus erythematosus etc. And also different combinations of the herbs are shown for above mentioned conditions.
The skin is, of course vulnerable to the effects of physical agents and chemical agents. The major function of skin is to preserve the constituents and compositions of the body contents.
The chemical composition and structure are significantly different in certain skin diseases such as psoriasis. The epidermis contains a constantly renewing cell population. In human the transit time from mitosis within the viable epidermis is on the urder of 12 to 14 days and within the stratum corneum about 15 days, for a total of about 28 days.
In psoriasis, however, it may be as short as 6 days. It has been found out that the proposed herbal compositions bring back the altered mechanisms to normal by altering the above specified transit time.
Herbal composition in the form of decoction given orally as well as given topically (in the form of ointment or cream) both synergetically help to reduce the inflammation and the severity of the immunae response.
There is possibility of transferring decoction into tablets form by using modern technologies.
HERBAL COMPOSITIONS AND MANAGEMENTS OF PSORIASIS ECZEMA AND LICHEN PLANUS The composition of the decoction for the first week of treatment: One teabag contains: Names Of The Herbs Weight in Grams Centratherum Anthelminticum (Fruit) 20 grams Trifla (Fruit) 10 grams Phyllantus Embelica Terminalia Chebula ) equal parts Terminalia Belerica Trikatu 10 grams Zingiber Officinalis ) (Root) Piper Longum ) (Fruit) equal parts Piper Nigrum ) (Fruit) Method: Above mentioned ingredients should be powdered and put into teabag by modern technology. The patient should be advised to prepare the fresh decoction every day. Every day early in the morning one teabag should be dropped in 150 ml of boiling water and then it should be covered with a lid. Keep it for 10 minutes and then it is divided into 3 parts. Each part to be taken 3 times a day.
Does - one tea bag for one day for an adult 70 kg weight. For adolescent the same dose. For children 6-7 years half the dose.
Effect: For relief of irritation and itching cycle - this is the most important composition.
It also relieves Urticaria (acute condition). For Urticaria the does could be 2 teabags per day divided into 6 parts in a day, repeated every 3 hours.
The composition for the management of psoriasis, eczema and Lichen planus for the second week of treatment: One teabag contains: Name Of The Herbs Weiaht in Grams Centratherum Anthelminticum (Fruit) 10 grams Trifla (Fruit) Phyllanthus Embelica Terminalia Chebula ) equal parts 10 grams Terminalia Belerica Hemidesmus Indicus (Roots) 1 gram Rubia Cordifolia (Roots) 2 gram Tinospora Cordifolia (Stem) 0.5 gram Berberis Aristata (Roots) 0.5 gram Curcuma Longa (Roots) 2.5 gram Smilex China (Roots) 1 gram Melia Azardiracta (Bark) 0.5 gram Glycerrhiza Glabra (Stem) 1 gram Picrorrhyza Curroa (Stem) 1 gram Method: - Above mentioned ingredients should be powdered and put into teabag by modern technology.
The patient should be advised to prepare the fresh decoction every day. Every day early in the morning one teabag should be dropped into 150 ml of boiling water and then it should be covered with a lid. Keep it for 10 minutes and then it is divided into 3 parts. Each part to be taken 3 times a day.
Dose - one teabag for one day for an adult of 70 kg weight.
For adolescent the same dose.
Effect: - For relief of accumulated stress and inflammation - this is the most important composition. Remains helpful in diabetic, hypertensive patients also.
And this composition could be continued for six weeks according to necessity.
It is also helpful to relieve Urticaria and neurodermatitis which are often seen frequently. No contraindications to pregnant ladies.
COMPOSITION FOR NIGHT CREAM MEANT FOR PSORIASIS INGREDIENTS: Name of The Herbs Weight in Grams Curcuma longa 15 Grams Curcuma Aromatica 15 Grams Berberis Aristata 15 Grams Terminalia Chebula 10 Grams Phyllanthus Embelica 10 Grams Terminalia Belerica 10 Grams Method: All the ingredients to be powdered and by adding boiled, cooled water make into fine paste. Now patient should to be advised not to throw away the contents of the teabags which were used for decoction. That means the patient should preserve the contents in a clean vessel and at night should mix this with small amount of above mentioned paste.
And that mixture can apply onto all psoriatic patches.
Effect: It is a good anti-inflammatory agent. Most useful in psoriatic arthropathy also.
Caution: Patient should be warned about the staining of the bed covers.
HERBAL COMPOSITIONS FOR THE PREPARATION OF THE CREAM FOR PSORIASIS. ECZENA AND LICHEN PLANUS Ingredients:- Amount Ghee 3 kg Water (Boiled and Cooled) 1 kg Decoction of Centratherum Anthelminticum 400 ml (400 ml water + 40 gram Centratherum Anthelminticum) Decoction of Trifla 200 ml (200 ml water + 20 gram Trifla) Decoction of Berberis Aristata 100 ml (100 ml water + 10 gram Berberis Aristata) Fresh Juice of Phyllanthus Embelica 200 ml Decoction of Melia Azardiracta 100 ml (100 ml water + 250 grams of leaves) Method: In a clean stainless steel vessel Hydrolysis of Ghee should be done with one Litre of water. Then after two to three days again further hydrolysis should be done with decoction of Centratherum Anthelminticum. Then after two to three days again further hydrolysis should be done with decoction of Trifla. Then after two to three days further hydrolysis should be done with fresh juice of Phyllanthus Embelica. Then after two to three days again further hydrolysis should be done with decoction of Melia Azardiracta (leaves). The cream becomes ready when it becomes unable to accimilate any extra amount of liquid.
For those psoriatic patients who are on methotraxate and wants to give in their creams decoction or powder of psorala coryhifolialinn can be added.
Effect: Relief of dryness, inflammation, irritation, rashes, papules, abrasions, discolouration faster than many other creams.
Caution: Though it is the cream made up of Ghee yet it should not be taken by mouth and kept out of reach of children.
Formula for Coffee Pharmaceutical preparation expected to be helpful in stress related problems and blessings for those who are in desperate need of a cup of coffee for their keep going.
It is now recognised that behaviourial depression is a fairly common consequence of stress (Solomon et al, 1985).
It is also evident that the animal's ability to cope with the stress largely influences the neurochemical consequences of stress. It is also recognised that exposure of living beings to inescapable and severe stress leads to depletion of central nor adrenaline and serotonin (Anisman et al, 1985) postulated to be the cause of endogenous depression.
A cup of ordinary coffee brings freshness when you wake up, but is definitely harmful when it is taken without milk and sugar off and on for keep going.
The innovative product contains 25% of coffee seeds 25% of cardamon seeds 50% of mixture of following herbs.
The names of the proposed herbs are: (a) Withenia Somnifera Dunal (Roots) (Indian Ginseng) (b) Asperagus Racemosus (Roots) (c) Tinospora Cordifolia (Stem) (d) Hemidesmus Indicus (Roots) 10 grams of the innovative coffee will contain 2,5 grams of coffee seeds 2.5 grams of cardamon seeds 2 grams of Hemidesmus Indicus 1 gram of Withenia Somnifera 1 gram of Asperagus Racemosus 1 gram of Tinospora Cordifolia.
This 10 grams is meant for one cup of coffee once a day only.
This pharmaceutical product will be blessings to human beings. By changing the lifestyle and release of maximum amount of overwhelming stress and we will be able to see tremendous changes in the world social, economical and psychological. And also stress induced gastric ulcers will be definitely healed.
HERBAL COMPOSITION FOR THE PREPARATION OF THE FOUNDATION CREAM FOR ANY HUMAN BEINGS INGREDIENTS: Amount Ghee 3 kg Water Boiled and Cooled 2 litre Decoction of Jasminum Florum (leaves) 1 litre (200 grams leaves) Sandalwood Powder 10 grams Sandalwood Oil 30 ml or Rose Oil 30 ml Method: Hydrolysis of Ghee is done with water and then done with decoction of Jasminum Florum. When complete trituration is over, may be for 6-7 hours then add Sandalwood Oil and again do trituration at the end add the Sandalwood Powder. Mix properly.
Effect: This Foundation Cream is meant for the protection of the skin from such deleterious effects of physical and chemical agents.
(Black people as well as many ladies, they use lightening agents for their make-up. Sometimes their skin become excessively damaged.) So this foundation cream may be used as an only cream or as a foundation cream. This is also for Infantile Eczema, skin care for diabetic patients, skin burnt due to overdoing of suntanning. For nappy rash in children it can be mixed with castor oil and zinc ointment. This can be for skincare of elderly people. This is a very soothing agent for postherpetic dermatitis. This should be helpful for any sort of newrodermatitis.
Cauton: Though it is the cream made up of Ghee yet it should not be taken by mouth and kept out of reach of children.

Claims (20)
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  1. CLAIMS:
    A process for the preparation of the cream for treating skin diseases comprises: (1) Hydrolysis of ghee with very important herbs as ingredients.
    In this process enough care is taken to ensure the harmony of all ingredients.
    Glycerrhiza and Curcuma longa has opposing action.
    Curcuma is a drying agent where as Glycerrhiza controls the over drying effect.
    Curcuma longa is keratolytic, anti-infective mild bactericidal, anti-inflammatory agent, mild anti-histaminic agent.
    When Curcuma longa joined with Centratherum anthelminticum and Berberis aristata and Trifla, it becomes Powerful anti-histaminic and more powerful anti-inflammatory agent. So this combination remains into action meant for both dry skin as well as weeping skin abrasions, discolouration of the skin, papules etc. Single combination for many different conditions and five different combinations for a single disease in a different state.
    This is a process claim plus most effective ingredients claim.
    (2) The Innovative product is in the form of Herbal cream which has preventative and curatative both types of aspects.
    (3) This Innovative process of preparation of creams is a little bit complicated - in other words the preparation requires many precautions during the process - even then easily manageable.
    (4) In this Innovative process of preparation of creams each and every ingredient takes active part and enough care is taken throughout the whole process to maintain harmony. Here each and every ingredient maintains the synergism and remains equally powerful thereby it results into the most effective product with profound results.
    (5) These Innovative products when used for curatative purposes, it is most effective or beneficial in chronic skin disorders, such as Eczema, Psoriasis, and Lichen planus, abrasion, discolouration.
    (6) Preparing the powder and subjecting the powder of said herbs to decoction with closed vessel, so volatile gases and essential oils are preserved.
    (7) The Combination of Tannins and other alkaloids remains helpful in maintaining the normal texture of the skin. Here Texture means normal thickness of all the dermis and epidermis.
    Management Claims: (8) Taking into consideration a etiopathology and lifestyle of the patients of chronic skin disorders.
    All combinations in the form of decoction, creams or coffee, they are meant for relief of stess: as well as they have Anti-Histaminic effects Anti-Inflammatory effects Adrenocortical stimulations Cortisol preservation Keratolytic agent Controlling the overdrying action Controlling the over secretory action Anti-Infective agents Anti-fungal agents Herbal Coffee is meant for changing in lifestyle and release of stress and release of stress is meant for breaking of the cycle of irritation pruritus inflammation - inflammation pruritus irritation.
    Herbal Creams for biodynamic massage proves to be more effective in cortisol preservation. Decoction to be taken orally is for purification of blood and helping in altering the immunae response.
    (9) During the first week of treatment, more powerful anti-histaminic agents are used.
    (10) During the second week of treatment, mixture of anti-histaminic and anti-inflammatory agents are used.
    (11) During the third week of treatment, and afterwards the combination remains the same, but you can increase the dose if necessary.
    (12) No contraindication for diabetic or hypertensive or pregnant woman patients.
    (13) These creams are applied on face also.
    Product Claims: (14) In the pharmaceutical composition of the Coffee by adding other ingredients side effects of the Coffee itself are minimised.
    Hemidesmus indilus imparts wonderful flavour cardamon has also its own flavour.
    So good compliance of the patients.
    All the ingredients remain helpful synergetically in relief of accumulated stress and also altered psychoimmunology of the patients is brought back to near normal condition.
    The balance between sympathetic and parasympathetic systems is well maintained.
    Physicians of traditional Aywrveda use nearly 40 to
    45 ingredients in one item. Here in these products only very important ones are selected and still harmonious effects are achieved. Decoction provides antihistaminic, adrenocortical stimulant and cortisol preserving agents also.
    Creams:- claims process and product together. By hydrolysis of Ghee with many decoctions many triglyaside pockets are formed. So each and every ingredient could remain together as well as separate in the cream that means each can impart its own effects without opposition.
    Cream itself is capable of providing Vitamin A, Vitamin D and Vitamin C all are important for the protection of all the layers of skin. LANOLIN FREE PRODUCTS.
    Amendments to the claims have been filed as follows 1. A composition for use in ameliorating skin disorders and/or promoting general health, which composition comprises herbal extracts derived from at least two of: Centratherium anthelminticum, Phvllanthus emblica, Hemidesmus indicus, Tinospora cordifolia and Curcuma lonaa; the herbal extracts being dispersed in a suitable carrier for topical application or being in the form of a dry powder for the preparation of a potable decoction.
  2. 2. A composition as claimed in claim 1, which comprises herbal extracts derived from two or more of: Centratherium anthelminticum, Phvllanthus emblica, and Curcuma lonqa.
  3. 3. A composition as claimed in claim 1, 2 or 3, which comprises extracts of Phvllanthus emblica, Terminalia chebula and Terminalia belerica.
  4. 4. A composition as claimed in claim 1, wherein the composition is formulated as an ointment or cream for topical application.
  5. 5. A composition as claimed in claim 1, wherein the composition is formulated in the manner of a teabag.
  6. 6. A composition as claimed in claim 1, wherein the composition is formulated in tablet form.
  7. 7. A composition as claimed in claim 2, wherein the herbal extracts are dispersed in ghee.
  8. 8. A composition as claimed in any preceding claim, which further comprises herbal extracts derived from Berberis aristata.
  9. 9. A composition as claimed in any preceding claim, which further comprises herbal extracts derived from Zinaiber officinalis.
  10. 10. A composition as claimed in any preceding claim, which further comprises herbal extracts derived from Piper lonaum.
  11. 11. A composition as claimed in any preceding claim, which further comprises herbal extracts derived from Piner niarum.
  12. 12. A composition as claimed in any preceding claim, which further comprises herbal extracts derived from Rubia cordifolia.
  13. 13. A composition as claimed in any preceding claim, which further comprises herbal extracts derived from Smilex china.
  14. 14. A composition as claimed in any preceding claim, which further comprises herbal extracts derived from Melia azardiracta.
  15. 15. A composition as claimed in any preceding claim, which further comprises herbal extracts derived from Glycerhiza glabra.
  16. 16. A composition as claimed in any preceding claim, which further comprises herbal extracts derived from Picrorhiza curroa.
  17. 17. A composition as claimed in any preceding claim, which further comprises herbal extracts derived from Curcuma aromatica.
  18. 18. A composition as claimed in any preceding claim, which further comprises herbal extracts derived from Asparaaus racemosus.
  19. 19. A composition as claimed in any preceding claim, which further comprises coffee.
  20. 20. A composition as claimed in any preceding claim, which further comprises cardamon seeds.