GB2188915A - Tablets - Google Patents

Tablets Download PDF

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Publication number
GB2188915A
GB2188915A GB08608602A GB8608602A GB2188915A GB 2188915 A GB2188915 A GB 2188915A GB 08608602 A GB08608602 A GB 08608602A GB 8608602 A GB8608602 A GB 8608602A GB 2188915 A GB2188915 A GB 2188915A
Authority
GB
United Kingdom
Prior art keywords
salt
tablets
particles
caking agent
tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB08608602A
Other versions
GB2188915B (en
GB8608602D0 (en
Inventor
Alan John Shipman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
British Salt Ltd
Original Assignee
British Salt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Salt Ltd filed Critical British Salt Ltd
Priority to GB8608602A priority Critical patent/GB2188915B/en
Publication of GB8608602D0 publication Critical patent/GB8608602D0/en
Publication of GB2188915A publication Critical patent/GB2188915A/en
Application granted granted Critical
Publication of GB2188915B publication Critical patent/GB2188915B/en
Expired legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01DCOMPOUNDS OF ALKALI METALS, i.e. LITHIUM, SODIUM, POTASSIUM, RUBIDIUM, CAESIUM, OR FRANCIUM
    • C01D3/00Halides of sodium, potassium or alkali metals in general
    • C01D3/22Preparation in the form of granules, pieces, or other shaped products
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01DCOMPOUNDS OF ALKALI METALS, i.e. LITHIUM, SODIUM, POTASSIUM, RUBIDIUM, CAESIUM, OR FRANCIUM
    • C01D3/00Halides of sodium, potassium or alkali metals in general
    • C01D3/26Preventing the absorption of moisture or caking of the crystals

Abstract

Tablets, pellets, blocks formed of particles of common salt or other crystallisable material can be produced without a tendency to disintegrate, even when an anti-caking agent is included in the material being tabletted, by moistening the tablet and then drying it, or by moistening the particles either just before or during the tabletting and then drying.

Description

SPECIFICATION Tablets This invention relates to tablets, pellets, blocks and the like (hereinafter referred to as "tablets") of salt or other crystalline material which may be of organic or inorganic nature. More particularly, though not exclusively, the present invention relates to tablets consisting of or comprising common salt (sodium chloride).
Common salt tablets are currently used for medicinal and culinary purposes. They are also used in water softening and, in the form of blocks, are used for animal licks. The function of such tablets is to enable controlled release or dissolving of the salt without premature disintegration of the tablet. For example, in the water softening field, it is undesirable for the salt tablet to disintegrate because the fine salt particles resulting from disintegration of the tablet can cause undue wear and sticking of automatic valves in the water softening system and does not lead to effective utilization of the salt.
It is common practice to include an anti-caking agent in salt in orderto maintain it in afree-running condition. In this way, handling, storage and transportof salt isfacilitated. Withoutthe provision of an anti-caking agent, the saltforms into solid lumps, which is highly undesirable, However, it has heretofore been impossible to form tablets having the required coherence (i.e. lackofatendencyto disintegrate) using salt containing an anti-caking agent. Thus, it has been the practice to form tablets from salt which does not contain an anti-caking agent, with all the attendant difficulties in handling, transport and storage.
Most surprisingly, we have now found thattablets having the required coherence can be produced from salt containing anti-caking agent if, afterthe tablet has been formed, it is moistened and then dried.
Thus, according to one aspect of the present invention, there is provided a method of manufacturing tablets (as herein defined) of particles of salt or other crystallisable material, comprising the steps of compacting such particles to form tablets, moistening the tablets, and then removing the moisture therefrom.
In an alternative embodiment, the salt is moistened slightly either just before or during the tabletting operation and is then dried. The moistened salt may be in the form of commercially available undried salt typically having a water content of about 2.5% Although the mechanism is not yet fully understood, it is believed that moistening ofthe tablet serves to dissolve a small proportion of the material at the surface of the particles and that, after removal of the moisture, bridges of salt or other crystalline material are established which extend between the particles in order to hold such particles in a coherent state, thus overcoming the effect of the anti-caking agent.
Thus, according to another aspect of the present invention,there is provided a tablet (as herein defined) of particles of salt or other crystallisable material, wherein the particles are held together in a coherent state within the tablet by bridges of said material which extend between the particles.
Whilstthe present invention is particularly concerned with tablets formed of salt or other crystallisable material which also contain an anti-caking agent, it will be appreqiated that the concept of the present invention can also be applied to tablets formed ofsaltorothercrystallisable material which do not contain an anti-caking agent if it is desired to improve furtherthe coherence of a tablet containing no anti-caking agent.
Typical anti-caking agents for common salt are aluminosilicatesofsodium or potassium, magnesium carbonate and sodium or potassium salts of carboxylic acid such as citric acid, oleic acid, stearic acid and palmitic acid, and the present invention is applicable to tablets containing such caking agents. In particular, however, the present invention is applicable to tablets formed of salt containing the hexacyanoferrate II salt of sodium or potassium, which is the most common anti-caking agent for common salt. The anti-caking agent is usally provided in the salt at a concentration in the range of 5 to 15 ppm by weight to provide the necesssaryanti-caking properties.
During the moistening step, the tablets can be moistened with water, either in the form of fine spray or droplets, or by briefly immersing thetablets in water. Alternatively,thetablets may be moistened with a solution of salt or other crystallisable material, e.g brine. Any concentration of solution up to a saturated solution may be used. The amount of liquid required is not critical, butwe have found that quite a light moistening of the surface ofthetablet appears to be sufficient. If it is desired to introduce other materials, such as trace elements, into the tablet, then these can be introduced conveniently by incorporating them into the solution used to moisten the tablets. For example, trace elements may be advantageously incorporated into the tablets when such areintheform of animal licks.
After moistening, the tablets are dried essentially to remove the added moisture. Drying can be effected by raising the temperature in an oven to a temperature typically between 1 000C and 200"C for a period of time to effect drying. Alternatively, the moistened tablets can be dried in a microwave oven.
In a particular example of the present invention, tablets are formed in a tabletting machine, (e.g a COLTON 31 STATION DOUBLE ROTATORY TABLET PRESS) using salt having a particle size distribution such that 2.5% of the particles are retained on an 850 micron sieve, 70% are retained on a 300 micron sieve and 99.9% are retained on a 75 micron sieve. The salt contains 5to 5 ppm by weight of sodium hexacyanoferrate II as an anti-caking agent and is better than 99.9% by weight pure sodium chloride.
Thetabletting machine produces tablets having a diameter of 5to 30 millimetres (in this example 25 mm) and athickness of 5to 20 mm (in this example 12 mm) but the tablet dimensions are not critical to the invention. After moistening the tablets with a fine water spray, the tablets are then dried in an oven at 1 70 C for 2 minutes. The resultanttablets are found to be coherent in use in that they do not disintegrate when immersed in water and this is believed to be due to bridges of salt which are formed between the salt particles within the tablet.

Claims (8)

1. A method of manufacturing tablets (as herein defined) of particles of salt or other crystallisable material, comprising the steps of compacting such particles to form tablets, moistening the tablets, and then removing the moisture therefrom.
2. A modification of the method as claimed in claim 1, wherein the salt is moistened slightly either just before or during the tabletting opeation and is then dried.
3. A method as claimed in claim 2, wherein the moistened salt is in the form of undried salttypically having a water content of about 2.5%.
4. A method as claimed in any preceding claim, wherein said tablets also contain an anti-caking agent.
5. Atablet (as herein defined) of particles of salt or other crystallisable material, wherein the particles are held together in a coherent state within the tablet by bridges of said material which extend between the particles.
6. Atablet as claimed in claim 5, which also contains an anti-caking agent.
7. A method as claimed in claim 1, substantially as hereinbefore described.
8. Atabletwhen produced bya method as claimed in anyone of claims 1 to 4 or claim 7.
GB8608602A 1986-04-09 1986-04-09 Tablets Expired GB2188915B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB8608602A GB2188915B (en) 1986-04-09 1986-04-09 Tablets

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8608602A GB2188915B (en) 1986-04-09 1986-04-09 Tablets

Publications (3)

Publication Number Publication Date
GB8608602D0 GB8608602D0 (en) 1986-05-14
GB2188915A true GB2188915A (en) 1987-10-14
GB2188915B GB2188915B (en) 1989-11-22

Family

ID=10595902

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8608602A Expired GB2188915B (en) 1986-04-09 1986-04-09 Tablets

Country Status (1)

Country Link
GB (1) GB2188915B (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0998921A1 (en) * 1998-09-22 2000-05-10 Sato Pharmaceutical Co., Ltd. Method and apparatus for manufacturing tablet capable of quick disintegration in oral cavity
FR2786760A1 (en) * 1998-12-07 2000-06-09 Solvay CYLINDRICAL PELLET OF AGGLOMERATED SALT
WO2000073208A1 (en) * 1999-05-27 2000-12-07 Akzo Nobel N.V. Pressed products of non-caking salt
US6491964B1 (en) 1999-05-27 2002-12-10 Akzo Nobel N.V. Pressed products of non-caking salt and process of making
EP1769682A1 (en) * 2004-07-02 2007-04-04 Meiji Dairies Corporation Solid milk and method of producing the same
CN101437404B (en) * 2005-12-28 2012-07-04 株式会社明治 Solid milk and method of making the same
WO2013001052A1 (en) 2011-06-30 2013-01-03 Eurotab Method for manufacturing soluble coffee tablets
DE102020124503A1 (en) 2020-09-21 2022-03-24 Showerplus Entwicklungs- Und Vertriebsgesellschaft Mbh Pressed shaped body and applicator for receiving such a shaped body

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB911130A (en) * 1959-11-10 1962-11-21 Dominion Tar & Chemical Co Salt production
GB1384384A (en) * 1971-08-27 1975-02-19 Ici Ltd Agglomeration of soluble particles
GB2104882A (en) * 1981-08-28 1983-03-16 Coal Ind Briquette for smelting process and method of its production

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB911130A (en) * 1959-11-10 1962-11-21 Dominion Tar & Chemical Co Salt production
GB1384384A (en) * 1971-08-27 1975-02-19 Ici Ltd Agglomeration of soluble particles
GB2104882A (en) * 1981-08-28 1983-03-16 Coal Ind Briquette for smelting process and method of its production

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
THE THEORY AND PRACTICE OF INDUSTRIAL PHARMACY LACKMAN LIEBERMAN & KANIG 2ND EDITION PAGES 321-358 *

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0998921A1 (en) * 1998-09-22 2000-05-10 Sato Pharmaceutical Co., Ltd. Method and apparatus for manufacturing tablet capable of quick disintegration in oral cavity
US6316026B1 (en) 1998-09-22 2001-11-13 Sato Pharmaceutical Co., Ltd. Method and apparatus for manufacturing tablet capable of quick disintegration in oral cavity
FR2786760A1 (en) * 1998-12-07 2000-06-09 Solvay CYLINDRICAL PELLET OF AGGLOMERATED SALT
EP1008554A1 (en) * 1998-12-07 2000-06-14 SOLVAY & Cie (Société Anonyme) Cylindrical pastille of agglomerated salt
WO2000073208A1 (en) * 1999-05-27 2000-12-07 Akzo Nobel N.V. Pressed products of non-caking salt
US6491964B1 (en) 1999-05-27 2002-12-10 Akzo Nobel N.V. Pressed products of non-caking salt and process of making
AU2005260485B2 (en) * 2004-07-02 2010-12-02 Meiji Dairies Corporation Solid milk and method of producing the same
EP1769682A4 (en) * 2004-07-02 2010-08-25 Meiji Dairies Corp Solid milk and method of producing the same
EP1769682A1 (en) * 2004-07-02 2007-04-04 Meiji Dairies Corporation Solid milk and method of producing the same
CN1980576B (en) * 2004-07-02 2012-07-18 株式会社明治 Solid milk and method of producing the same
US8828471B2 (en) 2004-07-02 2014-09-09 Meiji Co., Ltd. Method for manufacturing solid milk
CN101437404B (en) * 2005-12-28 2012-07-04 株式会社明治 Solid milk and method of making the same
US9635869B2 (en) 2005-12-28 2017-05-02 Meiji Co., Ltd. Solid milk and method of making the same
WO2013001052A1 (en) 2011-06-30 2013-01-03 Eurotab Method for manufacturing soluble coffee tablets
EP2725920B1 (en) * 2011-06-30 2016-03-16 Eurotab Method for manufacturing soluble coffee tablets
DE102020124503A1 (en) 2020-09-21 2022-03-24 Showerplus Entwicklungs- Und Vertriebsgesellschaft Mbh Pressed shaped body and applicator for receiving such a shaped body
EP3984518A1 (en) 2020-09-21 2022-04-20 Showerplus Entwicklungs- und Vertriebsgesellschaft mbH Pressed moulding and applicator for holding such a moulding

Also Published As

Publication number Publication date
GB8608602D0 (en) 1986-05-14
GB2188915B (en) 1989-11-22

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20010409