GB2159625A - Test monitor - Google Patents

Test monitor Download PDF

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Publication number
GB2159625A
GB2159625A GB08513611A GB8513611A GB2159625A GB 2159625 A GB2159625 A GB 2159625A GB 08513611 A GB08513611 A GB 08513611A GB 8513611 A GB8513611 A GB 8513611A GB 2159625 A GB2159625 A GB 2159625A
Authority
GB
United Kingdom
Prior art keywords
microprocessor
means
signals
input
monitoring apparatus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB08513611A
Other versions
GB2159625B (en
GB8513611D0 (en
Inventor
Peter Eric Krebs
Original Assignee
Peter Eric Krebs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB848413830A priority Critical patent/GB8413830D0/en
Application filed by Peter Eric Krebs filed Critical Peter Eric Krebs
Publication of GB8513611D0 publication Critical patent/GB8513611D0/en
Publication of GB2159625A publication Critical patent/GB2159625A/en
Application granted granted Critical
Publication of GB2159625B publication Critical patent/GB2159625B/en
Application status is Expired legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H15/00ICT specially adapted for medical reports, e.g. generation or transmission thereof
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation

Abstract

Microprocessor-controlled electronic monitoring apparatus comprising means for sensing conditions of a test to be monitored, such as blood glucose tests comprises a microprocessor (10), means (12) for storing control information and instructions for the microprocessor to compare test- dependent input signals (via 18, 16) against control information and produce test result signals, and means (14) for presenting those test result signals in a manner intelligible to the user. A further store (22) is provided for information signals input (via 20) the apparatus in connection with specific test monitoring operations by the user, and the first-mentioned means (12) for storing further includes instructions for use by the microprocessor of such input information signals. <IMAGE>

Description

SPECIFICATION Test monitor The invention is described specifically in relation to monitor-type equipment for making medical-type tests, actually for blood glucose level, but is believed to have more general application to portable or occasionally used equipment of a micro-electric nature utilising a microprocessor for control purposes and wherein certain parameters are preset at production or otherwise prior to end-use, and where there may be advantage in or need for the end-user being able to modify same and /or save on subsidiary set-up or conditioning procedures that would obtain for the user for at least some period of time and number of uses of the equipment and/or reduce any requirement for record keeping. In general, of course, such parameters or other information result from end-use and are of more than purely transient or "one-off" value.

In the above-mentioned specific application to blood glucose monitoring, primary concern is with equipment for home use by patients, typically diabetics, using so-called "dry strip" techniques. Such strips sensitised for response to application of a small blood sample, say from a finger-prick, in a manner detectable by optically, usually by reflection from the strip in a suitable sensor station, are available from different sources with different characteristics, e.g. from Boehringer Mannheim and Ames. The specific equipment of immediate interest can cope with such different strips, but, further and importantly, also with variations from batch to batch of strips from the same source in order to achieve and maintain good accuracy.In practice, a calibration procedure is provided using test strips of known characteristics and it would be useful to be able to avoid recalibration at each equipment use, at least for strips from the same batch. There is also an everpresent desirability for the user to keep and consult a record of previous results of using the monitor.

According to this invention there is provided microprocessor-controlled electronic monitoring apparatus comprising means for sensing conditions of a test to be monitored and providing input signals for the microprocessor, means for storing control information and instructions for the microprocessor to compare said input signals against said control information and produce test result signals and means for presenting those test result signals in a manner intelligible to the user, wherein a further store is provided for information signals input the apparatus in connection with specific test monitoring operations by the user, and the first-mentioned means for storing further includes instructions for use by the microprocessor of such input information signals.

Thus, in preferred embodiments of this invention, provision is made for so-called nonvolatile storage of user-originating information, i.e. separately from the basic microelectric components usually comprising a microprocessor a program-and-parameter store of permanent type (PROM or ROM), input, control and display or other output means, all interconnected with the microprocessor for appropriate entry and use of the contents of the non-volatile storage, usually under control of some extended capability installed in the basic program-and-parameter store.

In effect, in terms of contemporary developments in micro-electronics, such provision can be achieved readily using a single additional circuit unit or chip of the now-available nonvolatile RAM type, or even low-power RAM, e.g. of CMOS type, backed by a small battery, i.e. effectively non-volatile. Any necessary additional control entry means, such as pushbutton or other pressure- or skin-sensitive switches or further-level operation of existing entry means, is, of course, readily provided.

It is particularly advantageous to incorporate into a microprocessor-based blood glucose monitor hereof just such a non-volatile store affording retention and use of data comprising user-originating calibration parameters and results of the last n readings of the monitor, if not also modifiers or replacements for basic parameters.

The basic parameters of blood glucose monitors of this invention concern response time of the strip (actually longer for Boehringer Mannheim's than for Ame's) and the actual level of response as seen by the optical system at the strip station. The preferred monitor has count-down facilities to indicate the response time, actually giving audible indication of expiry, i.e. when it is appropriate to take a reading, typically at insertion and then after wiping the strip.

A system hereof is, in fact, shown in block diagram outline format in the accompanying drawings. There, a microprocessor chip 10 will be connected on a printed circuit board with a permanent program-and-basic parameter store 12 (PROM or ROM), a display 14 of LED or LCD type (typically 3-digits), an analog-to-digital converter 16 fed from an optical strip-sensing station 18 (typically of reflection measuring type), an operator-actuatable control input key pad 20 (typically three push-buttons), and, specifically for the purposes of this invention, an effectively nonvolatile RAM chip 22.

It is practical for the read-only store 12 to have control programs and parameters in the form of a basic correlation or function-law between reflection signal levels and corresponding glucose level and relative to "nominal" calibration results (typically for high and low levels at test strips), and a correction algorithm in relation to "actual" calibration results in relation to how they differ from "nominal". Hitherto the "actual" calibration results and the "real" test results would have resided only in the microprocessor 10.Now, however, they can be written to the nonvolatile store 22, say (for the "real" test results) on an automatic "stack" type basis (to hold last n readings), controlled by further "housekeeping" program routines of the store 12, i.e. additional to normally-resident timing, display control, equipment set-up, calibration, etc. routines.

It will thus be evident that the last-made calibration results can be held and used automatically, and that a diary of the last n readings can be held and called up for sequential display as desired. Moreover, it should be further evident that input means could even be provided, or serve, for entering alternatives to the basic correlation or function-law, which could lead to much-enhanced versatility of our monitor additional to greater ease of user-operation.

Having thus described the drawing, and now returning to the aforementioned basic parameters including correlations, it is believed that suitable dry strips will allow application to other than human blood glucose monitoring for diabetics, for example to measure glucose levels in milk, water or vegetables, to monitor animals for some glucoselevel affecting condition like pregnancy, even to monitor such things as haemoglobin, etc.

in connection with portable medical laboratory equipment of particular application and interest in the so-called third world.

Claims (8)

1. Microprocessor-controlled electronic monitoring apparatus comprising means for sensing conditions of a test to be monitored and providing input signals for the microprocessor, means for storing control information and instructions for the microprocessor to compare said input signals against said control information and produce test result signals and means for presenting those test result signals in a manner intellegible to the user, wherein a further store is provided for information signals input the apparatus in connection with specific test monitoring operations by the user, and the first-mentioned means for storing further includes instructions for use by the microprocessor of such input information signals.
2. Microprocessor-controlled electronic monitoring apparatus according to claim 1 comprising user-operable means for inputting control and/or information signals including said input information signals.
3. Microprocessor-controlled electronic monitoring apparatus according to claim 1 or claim 2, wherein the means for presenting comprises visual display means controlled by the microprocessor automatically and/or at user command.
4. Microprocessor-controlled electronic monitoring apparatus according to any preceding claim, wherein the input information signals include selected prior result signals.
5. Microprocessor-controlled electronic monitoring apparatus according to claim 4, wherein said selected prior result signals are for the last n operations of the apparatus.
6. Microprocessor-controlled electronic monitoring apparatus according to any preceding claim, wherein the first-mentioned means for storing comprises a semi-conductor memory device of read-only type and the further means for storing comprises a semiconductor memory device of effectively nonvolatile writable type.
7. Microprocessor-controlled electronic monitoring apparatus according to any preceding claim constituting a blood glucose monitor using strips sensitised for response to small blood samples with such response optically sensable by said means for sensing and the further means for storing includes at least user-input designation of type of strip used and results from a test strip for calibration purposes.
8. Microprocessor-controlled electronic monitoring apparatus substantially as herein described with reference to and as shown in the accompanying drawing.
GB8513611A 1984-05-31 1985-05-30 Glucose test monitor Expired GB2159625B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB848413830A GB8413830D0 (en) 1984-05-31 1984-05-31 Blood glucose monitor

Publications (3)

Publication Number Publication Date
GB8513611D0 GB8513611D0 (en) 1985-07-03
GB2159625A true GB2159625A (en) 1985-12-04
GB2159625B GB2159625B (en) 1989-06-21

Family

ID=10561725

Family Applications (2)

Application Number Title Priority Date Filing Date
GB848413830A Pending GB8413830D0 (en) 1984-05-31 1984-05-31 Blood glucose monitor
GB8513611A Expired GB2159625B (en) 1984-05-31 1985-05-30 Glucose test monitor

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB848413830A Pending GB8413830D0 (en) 1984-05-31 1984-05-31 Blood glucose monitor

Country Status (2)

Country Link
AU (1) AU4304885A (en)
GB (2) GB8413830D0 (en)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0275390A1 (en) * 1987-01-03 1988-07-27 Institut für Diabetestechnologie Gemeinnützige Forschungs - und Entwicklungsgesellschaft mbH Implantable electrochemical sensor
GB2204124A (en) * 1987-04-04 1988-11-02 Martin Robert Kent Blood sample monitoring device
EP0462466A2 (en) * 1990-06-20 1991-12-27 Bayer Corporation Portable electronic logbook and method of storing and displaying data
EP0637808A2 (en) * 1993-07-27 1995-02-08 Bayer Corporation Buttonless memory system for an electronic measurement device
US5506600A (en) * 1988-10-28 1996-04-09 Canon Kabushiki Kaisha Driving apparatus
WO1999005966A1 (en) * 1997-08-01 1999-02-11 Hypoguard Limited Device for testing analyte concentration in a fluid
EP1172653A1 (en) * 2000-02-18 2002-01-16 ARKRAY, Inc. Inspection chip for sensor measuring instrument
EP1267708A2 (en) * 2000-03-29 2003-01-02 The University of Virginia Patent Foundation Method, system, and computer program product for the evaluation of glycemic control in diabetes from self-monitoring data
USD611151S1 (en) 2008-06-10 2010-03-02 Lifescan Scotland, Ltd. Test meter
USD611372S1 (en) 2008-09-19 2010-03-09 Lifescan Scotland Limited Analyte test meter
USD611489S1 (en) 2008-07-25 2010-03-09 Lifescan, Inc. User interface display for a glucose meter
USD611853S1 (en) 2008-03-21 2010-03-16 Lifescan Scotland Limited Analyte test meter
USD612275S1 (en) 2008-03-21 2010-03-23 Lifescan Scotland, Ltd. Analyte test meter
USD612274S1 (en) 2008-01-18 2010-03-23 Lifescan Scotland, Ltd. User interface in an analyte meter
USD615431S1 (en) 2008-03-21 2010-05-11 Lifescan Scotland Limited Analyte test meter
US8538703B2 (en) 2002-08-13 2013-09-17 University Of Virginia Patent Foundation Method, system, and computer program product for the processing of self-monitoring blood glucose(SMBG)data to enhance diabetic self-management
US8917184B2 (en) 2008-03-21 2014-12-23 Lifescan Scotland Limited Analyte testing method and system

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2017903A (en) * 1978-03-31 1979-10-10 Bosch F Van Den Spectroscopic analysis
GB2024418A (en) * 1978-06-30 1980-01-09 Hycel Inc Automatic chemical kinetic and end-point analysis
GB2040038A (en) * 1978-11-28 1980-08-20 Hell R Dr Ing Gmbh Methods and circuit for the recognition of colours
US4313735A (en) * 1979-08-22 1982-02-02 Hitachi, Ltd. Automatic chemical analyzing method and apparatus
WO1983000065A1 (en) * 1981-06-24 1983-01-06 Price, Gerald, W. Automatic tracking system for a second derivative spectrometer
GB2102647A (en) * 1980-11-24 1983-02-02 Oximetrix Signal filter method and apparatus
GB2128736A (en) * 1982-10-21 1984-05-02 Exxon Resources Canada Apparatus and method for determining the hydrogen content of a substance
GB2135770A (en) * 1982-12-27 1984-09-05 Shimadzu Corp Spectrophotometer

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2017903A (en) * 1978-03-31 1979-10-10 Bosch F Van Den Spectroscopic analysis
GB2024418A (en) * 1978-06-30 1980-01-09 Hycel Inc Automatic chemical kinetic and end-point analysis
GB2040038A (en) * 1978-11-28 1980-08-20 Hell R Dr Ing Gmbh Methods and circuit for the recognition of colours
US4313735A (en) * 1979-08-22 1982-02-02 Hitachi, Ltd. Automatic chemical analyzing method and apparatus
GB2102647A (en) * 1980-11-24 1983-02-02 Oximetrix Signal filter method and apparatus
WO1983000065A1 (en) * 1981-06-24 1983-01-06 Price, Gerald, W. Automatic tracking system for a second derivative spectrometer
GB2128736A (en) * 1982-10-21 1984-05-02 Exxon Resources Canada Apparatus and method for determining the hydrogen content of a substance
GB2135770A (en) * 1982-12-27 1984-09-05 Shimadzu Corp Spectrophotometer

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4919141A (en) * 1987-01-03 1990-04-24 Institute fur Diabetestechnologie Gemeinnutzige Forschungs- und Entwicklungsgesellschaft mbH Implantable electrochemical sensor
EP0275390A1 (en) * 1987-01-03 1988-07-27 Institut für Diabetestechnologie Gemeinnützige Forschungs - und Entwicklungsgesellschaft mbH Implantable electrochemical sensor
GB2204124A (en) * 1987-04-04 1988-11-02 Martin Robert Kent Blood sample monitoring device
US5506600A (en) * 1988-10-28 1996-04-09 Canon Kabushiki Kaisha Driving apparatus
EP0462466A2 (en) * 1990-06-20 1991-12-27 Bayer Corporation Portable electronic logbook and method of storing and displaying data
EP0462466A3 (en) * 1990-06-20 1993-01-13 Miles Inc. Portable electronic logbook and method of storing and displaying data
EP0637808A3 (en) * 1993-07-27 1996-04-03 Miles Inc Buttonless memory system for an electronic measurement device.
EP0637808A2 (en) * 1993-07-27 1995-02-08 Bayer Corporation Buttonless memory system for an electronic measurement device
WO1999005966A1 (en) * 1997-08-01 1999-02-11 Hypoguard Limited Device for testing analyte concentration in a fluid
US6792791B2 (en) 2000-02-18 2004-09-21 Matsushita Electric Industrial Co., Ltd. Inspection chip for sensor measuring instrument
EP1172653A1 (en) * 2000-02-18 2002-01-16 ARKRAY, Inc. Inspection chip for sensor measuring instrument
EP1172653A4 (en) * 2000-02-18 2003-07-16 Matsushita Electric Ind Co Ltd Inspection chip for sensor measuring instrument
US7874985B2 (en) 2000-03-29 2011-01-25 University Of Virginia Patent Foundation Method, system, and computer program product for the evaluation of glycemic control in diabetes from self-monitoring data
JP2003528330A (en) * 2000-03-29 2003-09-24 ユニバーシテイ・オブ・バージニア・パテント・フアウンデーシヨン How to evaluate the glycemic control of diabetes from self-monitoring data, system and computer program product
EP1267708A2 (en) * 2000-03-29 2003-01-02 The University of Virginia Patent Foundation Method, system, and computer program product for the evaluation of glycemic control in diabetes from self-monitoring data
CN100448392C (en) 2000-03-29 2009-01-07 弗吉尼亚大学专利基金会 Method, system and computer program product for the evaluation of glycemic control in diabetes from self-monitoring data
JP4891511B2 (en) * 2000-03-29 2012-03-07 ユニバーシテイ・オブ・バージニア・パテント・フアウンデーシヨン How to evaluate the glycemic control of diabetes from self-monitoring data, system and computer program product
EP1267708A4 (en) * 2000-03-29 2006-04-12 Univ Virginia Method, system, and computer program product for the evaluation of glycemic control in diabetes from self-monitoring data
US8538703B2 (en) 2002-08-13 2013-09-17 University Of Virginia Patent Foundation Method, system, and computer program product for the processing of self-monitoring blood glucose(SMBG)data to enhance diabetic self-management
USD612274S1 (en) 2008-01-18 2010-03-23 Lifescan Scotland, Ltd. User interface in an analyte meter
USD612279S1 (en) 2008-01-18 2010-03-23 Lifescan Scotland Limited User interface in an analyte meter
USD611853S1 (en) 2008-03-21 2010-03-16 Lifescan Scotland Limited Analyte test meter
USD615431S1 (en) 2008-03-21 2010-05-11 Lifescan Scotland Limited Analyte test meter
USD612275S1 (en) 2008-03-21 2010-03-23 Lifescan Scotland, Ltd. Analyte test meter
US8917184B2 (en) 2008-03-21 2014-12-23 Lifescan Scotland Limited Analyte testing method and system
US9626480B2 (en) 2008-03-21 2017-04-18 Lifescan Scotland Limited Analyte testing method and system
USD611151S1 (en) 2008-06-10 2010-03-02 Lifescan Scotland, Ltd. Test meter
USD611489S1 (en) 2008-07-25 2010-03-09 Lifescan, Inc. User interface display for a glucose meter
USD611372S1 (en) 2008-09-19 2010-03-09 Lifescan Scotland Limited Analyte test meter

Also Published As

Publication number Publication date
GB8413830D0 (en) 1984-07-04
AU4304885A (en) 1985-12-05
GB2159625B (en) 1989-06-21
GB8513611D0 (en) 1985-07-03

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Legal Events

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PCNP Patent ceased through non-payment of renewal fee

Effective date: 19920530