GB2086937B - Production of human monoclonal antibodies by human hybridomas - Google Patents

Production of human monoclonal antibodies by human hybridomas

Info

Publication number
GB2086937B
GB2086937B GB8133387A GB8133387A GB2086937B GB 2086937 B GB2086937 B GB 2086937B GB 8133387 A GB8133387 A GB 8133387A GB 8133387 A GB8133387 A GB 8133387A GB 2086937 B GB2086937 B GB 2086937B
Authority
GB
United Kingdom
Prior art keywords
human
production
monoclonal antibodies
hybridomas
human monoclonal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8133387A
Other languages
English (en)
Other versions
GB2086937A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WILSTAR INST
Original Assignee
WILSTAR INST
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WILSTAR INST filed Critical WILSTAR INST
Publication of GB2086937A publication Critical patent/GB2086937A/en
Application granted granted Critical
Publication of GB2086937B publication Critical patent/GB2086937B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GB8133387A 1980-11-07 1981-11-05 Production of human monoclonal antibodies by human hybridomas Expired GB2086937B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20483280A 1980-11-07 1980-11-07

Publications (2)

Publication Number Publication Date
GB2086937A GB2086937A (en) 1982-05-19
GB2086937B true GB2086937B (en) 1985-05-30

Family

ID=22759633

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8133387A Expired GB2086937B (en) 1980-11-07 1981-11-05 Production of human monoclonal antibodies by human hybridomas

Country Status (12)

Country Link
JP (1) JPS57126424A (enrdf_load_stackoverflow)
AT (1) AT380898B (enrdf_load_stackoverflow)
AU (1) AU548738B2 (enrdf_load_stackoverflow)
BE (1) BE891003A (enrdf_load_stackoverflow)
CA (1) CA1198066A (enrdf_load_stackoverflow)
CH (1) CH658070A5 (enrdf_load_stackoverflow)
DE (1) DE3144181A1 (enrdf_load_stackoverflow)
FR (1) FR2493865A1 (enrdf_load_stackoverflow)
GB (1) GB2086937B (enrdf_load_stackoverflow)
IT (1) IT1140050B (enrdf_load_stackoverflow)
NZ (1) NZ198851A (enrdf_load_stackoverflow)
SE (1) SE460907B (enrdf_load_stackoverflow)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1200484A (en) * 1981-12-08 1986-02-11 Medical University Of South Carolina Human monoclonal antibodies and lymphokines
US4618577A (en) * 1983-02-09 1986-10-21 The Regents Of The University Of California Human-human hybridoma, CLNH5
JPS58201994A (ja) * 1982-05-21 1983-11-25 Hideaki Hagiwara 抗原特異的ヒト免疫グロブリンの生産方法
CA1247538A (en) * 1982-05-21 1988-12-28 Mark C. Glassy Human-human hybridomas for solid tumors
JPS58205773A (ja) * 1982-05-27 1983-11-30 Canon Inc インクジエツトプリンタ
EP0096839B1 (en) * 1982-06-09 1989-01-25 Asahi Kasei Kogyo Kabushiki Kaisha Method for producing human antibody
US4744982A (en) * 1982-08-24 1988-05-17 Hunter Kenneth W Human monoclonal antibody reactive with polyribosylribitol phosphate
US4689299A (en) * 1982-09-30 1987-08-25 University Of Rochester Human monoclonal antibodies against bacterial toxins
AU567693B2 (en) 1982-09-30 1987-12-03 University Of Rochester Human monoclonal antibodies against bacterial toxins
IL70686A (en) * 1983-01-20 1988-07-31 Suntory Ltd Mutant tumor cell lines for use in the preparation of hybridomas and the hybridomas obtained therefrom
US4613576A (en) * 1983-03-09 1986-09-23 Sloan-Kettering Institute For Cancer Research Human monoclonal antibodies to cancer cells
US4693966A (en) * 1983-03-11 1987-09-15 Sloan-Kettering Institute For Cancer Research Human monoclonal antibodies from lymphocytes of patients with malignant melanoma
CA1218947A (en) * 1983-04-06 1987-03-10 Pearl M.J. Chen Human hybrid cell lines
JPS6133125A (ja) * 1984-07-25 1986-02-17 Morinaga & Co Ltd ヒト単クロ−ン性抗肺ガン細胞抗体
JPS61104796A (ja) * 1984-10-26 1986-05-23 Chemo Sero Therapeut Res Inst モノクロ−ナル抗体の製造方法
US4677070A (en) * 1985-04-26 1987-06-30 Cetus Corporation Pseudomonas aeruginosa exotoxin A antibodies, their preparation and use
EP0239102A3 (en) * 1986-03-28 1989-07-12 Tsuji, Kimiyoshi Process for the formation of human-human hybridoma
AU3432389A (en) * 1988-04-07 1989-11-03 Farmitalia Carlo Erba S.R.L. Human monoclonal antibodies against rabies virus
CA2002067A1 (en) 1988-11-09 1990-05-09 Tamotsu Fukuda Parent cell line for producing human hybridomas
US5750106A (en) * 1993-01-28 1998-05-12 Novartis Ag Human monoclonal antibodies to cytomegalovirus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies

Also Published As

Publication number Publication date
GB2086937A (en) 1982-05-19
FR2493865A1 (fr) 1982-05-14
JPS57126424A (en) 1982-08-06
CH658070A5 (fr) 1986-10-15
ATA476381A (de) 1985-12-15
CA1198066A (en) 1985-12-17
AU548738B2 (en) 1986-01-02
FR2493865B1 (enrdf_load_stackoverflow) 1984-12-14
BE891003A (fr) 1982-03-01
SE460907B (sv) 1989-12-04
NZ198851A (en) 1984-07-31
DE3144181A1 (de) 1982-09-09
IT1140050B (it) 1986-09-24
AT380898B (de) 1986-07-25
SE8106528L (sv) 1982-05-08
AU7716781A (en) 1982-05-13
IT8124862A0 (it) 1981-11-04

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19931105