GB2072164B - 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivatives a process for the preparation of the derivatives and antitumor agents containing the derivatives - Google Patents

2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivatives a process for the preparation of the derivatives and antitumor agents containing the derivatives

Info

Publication number
GB2072164B
GB2072164B GB8104375A GB8104375A GB2072164B GB 2072164 B GB2072164 B GB 2072164B GB 8104375 A GB8104375 A GB 8104375A GB 8104375 A GB8104375 A GB 8104375A GB 2072164 B GB2072164 B GB 2072164B
Authority
GB
United Kingdom
Prior art keywords
derivatives
deoxy
alkylcarbonyl
preparation
fluorouridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8104375A
Other languages
English (en)
Other versions
GB2072164A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Funai Pharmaceutical Industries Ltd
Original Assignee
Funai Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1740880A external-priority patent/JPS56115799A/ja
Priority claimed from JP11210280A external-priority patent/JPS5735596A/ja
Priority claimed from JP55126776A external-priority patent/JPS5751000A/ja
Application filed by Funai Pharmaceutical Industries Ltd filed Critical Funai Pharmaceutical Industries Ltd
Publication of GB2072164A publication Critical patent/GB2072164A/en
Application granted granted Critical
Publication of GB2072164B publication Critical patent/GB2072164B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
GB8104375A 1980-02-15 1981-02-12 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivatives a process for the preparation of the derivatives and antitumor agents containing the derivatives Expired GB2072164B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1740880A JPS56115799A (en) 1980-02-15 1980-02-15 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivative, its preparation, and antitumor agnet containing the same
JP11210280A JPS5735596A (en) 1980-08-13 1980-08-13 Ester derivative of deoxyfluorouridine
JP55126776A JPS5751000A (en) 1980-09-11 1980-09-11 Ester derivative of alkoxybenzoyldeoxyfluorouridine

Publications (2)

Publication Number Publication Date
GB2072164A GB2072164A (en) 1981-09-30
GB2072164B true GB2072164B (en) 1983-12-21

Family

ID=27281812

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8104375A Expired GB2072164B (en) 1980-02-15 1981-02-12 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivatives a process for the preparation of the derivatives and antitumor agents containing the derivatives

Country Status (7)

Country Link
AT (1) AT374203B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH646715A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3105111A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8206550A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2476086A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2072164B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1210989B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0082668A1 (en) * 1981-12-18 1983-06-29 Beecham Group Plc 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections
CA1227794A (en) * 1983-05-23 1987-10-06 Jun-Ichi Yamashita 2'-deoxy-5- substituted uridine derivatives, processes for preparing the same and antitumor agent containing the same
US4864021A (en) * 1984-10-30 1989-09-05 Otsuka Pharmaceutical Co., Ltd. 5-fluorouracil derivatives
DE3588036T2 (de) * 1984-10-30 1995-11-16 Otsuka Pharma Co Ltd 5-Fluoruracilderivate.
ES2058073T3 (es) * 1986-04-30 1994-11-01 Otsuka Pharma Co Ltd Derivados de 5-fluorouracilo.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5924999B2 (ja) * 1978-06-10 1984-06-13 富山化学工業株式会社 新規な５−フルオロ−２′−デオキシ−β−ウリジン誘導体の製造法
JPS5535057A (en) * 1978-09-05 1980-03-11 Funai Corp 2'-deoxy-5-fluorouridine derivative, its preparation, and antitumor agent comprising it

Also Published As

Publication number Publication date
FR2476086A1 (fr) 1981-08-21
ES499443A0 (es) 1982-08-16
ES8206550A1 (es) 1982-08-16
DE3105111C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-08-12
DE3105111A1 (de) 1981-12-24
IT8119758A0 (it) 1981-02-13
CH646715A5 (de) 1984-12-14
ATA69181A (de) 1983-08-15
AT374203B (de) 1984-03-26
GB2072164A (en) 1981-09-30
FR2476086B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-01-06
IT1210989B (it) 1989-09-29

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19960212