GB2000186A - Method of producing antibodies in vitro - Google Patents
Method of producing antibodies in vitroInfo
- Publication number
- GB2000186A GB2000186A GB7826758A GB7826758A GB2000186A GB 2000186 A GB2000186 A GB 2000186A GB 7826758 A GB7826758 A GB 7826758A GB 7826758 A GB7826758 A GB 7826758A GB 2000186 A GB2000186 A GB 2000186A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cells
- large amounts
- cell hybrids
- fused cell
- vitro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000338 in vitro Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 7
- 206010035226 Plasma cell myeloma Diseases 0.000 abstract 2
- 206010022000 influenza Diseases 0.000 abstract 2
- 201000000050 myeloid neoplasm Diseases 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 1
- 210000000628 antibody-producing cell Anatomy 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 210000004989 spleen cell Anatomy 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80685777A | 1977-06-15 | 1977-06-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB2000186A true GB2000186A (en) | 1979-01-04 |
Family
ID=25194989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7826758A Withdrawn GB2000186A (en) | 1977-06-15 | 1978-06-13 | Method of producing antibodies in vitro |
Country Status (19)
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0014519A3 (en) * | 1979-01-09 | 1981-01-07 | National Research Development Corporation | Cell lines, process for preparing them and process for producing antibodies |
| EP0038642A1 (en) * | 1980-04-09 | 1981-10-28 | National Research Development Corporation | A monoclonal antibody against hepatitis B and its production, a hybridoma producing the monoclonal antibody and compositions containing it, the propagation of the hybridoma and the monoclonal antibody for use as an antiviral agent against hepatitus B and in isolating hepatitus b surface antigen from a sample |
| EP0027657A3 (en) * | 1979-10-22 | 1981-10-28 | The Massachusetts General Hospital | Process for producing antibodies to hepatitis virus and cell lines therefor |
| US4608337A (en) * | 1980-11-07 | 1986-08-26 | The Wistar Institute | Human hybridomas and the production of human monoclonal antibodies by human hybridomas |
| US4883752A (en) * | 1984-10-26 | 1989-11-28 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Method for preparing monoclonal antibody to Hbsag |
| US5204095A (en) * | 1980-04-09 | 1993-04-20 | National Research Development Corporation | Monoclonal antibodies against hepatitis B virus |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2963410D1 (en) | 1978-08-10 | 1982-09-16 | Schering Ag | Process for obtaining murine immunglobulin-e antibodies, hybrid cell lines used in the process and the process for preparing them, application of the immunglobulin-e antibodies so obtained |
| NL185309C (nl) * | 1980-07-28 | 1990-03-01 | Akzo Nv | Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens. |
| JPS5825439B2 (ja) * | 1980-12-30 | 1983-05-27 | 株式会社林原生物化学研究所 | ヒト副甲状腺ホルモンの製造方法 |
| JPS609795B2 (ja) * | 1980-12-11 | 1985-03-13 | 株式会社林原生物化学研究所 | ヒト上皮細胞成長因子の製造方法 |
| JPS58500366A (ja) * | 1981-03-06 | 1983-03-10 | セルテツク リミテツド | 単一クロ−ン抗体 |
| AU567693B2 (en) * | 1982-09-30 | 1987-12-03 | University Of Rochester | Human monoclonal antibodies against bacterial toxins |
| JPH03271235A (ja) * | 1983-04-08 | 1991-12-03 | Kureha Chem Ind Co Ltd | 抗カンジダ菌抗体分泌ハイブリドーマ |
| JPS60104020A (ja) * | 1983-10-14 | 1985-06-08 | メルク エンド カムパニー インコーポレーテツド | Ａ型肝炎‐タンパク質サブユニツト抗原 |
| US4707442A (en) * | 1983-10-24 | 1987-11-17 | Board Of Regents, The University Of Texas System | Hybrid cell line producing monoclonal antibody cytolytic to Trichomonas vaginalis |
| US5053224A (en) * | 1983-11-07 | 1991-10-01 | Hilary Koprowski | Induction of antibody response to solid tumors with anti-idiotype antibodies |
| US4731237A (en) * | 1983-11-07 | 1988-03-15 | The Wistar Institute | Immune response to virus induced by anti-idiotype antibodies |
| NL8401221A (nl) * | 1984-04-16 | 1985-11-18 | Innovi Nv | Analytische toepassing van fagocyt-cellijnen. |
| JPS6140800A (ja) * | 1984-07-27 | 1986-02-27 | バイオテクノロジー アンド エクスペリメンタル リサーチ インコーポレーテツド | 電気細胞融合法を用いたモノクローナル抗体の製造方法 |
| JPS6181782A (ja) * | 1984-09-28 | 1986-04-25 | Teijin Ltd | 抗ウイルス・ヒト抗体を産生するマウス−ヒトハイブリド−マ及びその製造法並びにその使用方法 |
| EP0198086B1 (en) * | 1984-09-28 | 1991-01-16 | Teijin Limited | Mouse human hybridoma producing antivirus human antibody, process for its preparation, and antivirus human monoclonal antibody |
| JPS6226300A (ja) * | 1984-10-10 | 1987-02-04 | セントコ−・インコ−ポレ−テツド | Ｈｔｌｖ−３ｄｎａのクロ−ニングおよび発現 |
| GB8501473D0 (en) * | 1985-01-21 | 1985-02-20 | Pasteur Institut | Cloned dna sequences |
| JP2518607B2 (ja) * | 1985-08-29 | 1996-07-24 | 雪印乳業株式会社 | インフルエンザａ型ウイルスｈａ抗原に対するモノクロ―ナル抗体およびその作成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3423505A (en) * | 1964-10-31 | 1969-01-21 | Univ Toronto | Rabies vaccine and process for preparation thereof |
| US3585266A (en) * | 1969-02-24 | 1971-06-15 | Dow Chemical Co | Live rabies virus vaccine and method for the production thereof |
-
1978
- 1978-06-07 FI FI781818A patent/FI64952C/fi not_active IP Right Cessation
- 1978-06-07 ZA ZA00783261A patent/ZA783261B/xx unknown
- 1978-06-09 SE SE7806729A patent/SE7806729L/xx unknown
- 1978-06-12 FR FR7817545A patent/FR2394607A1/fr active Granted
- 1978-06-13 GB GB7826758A patent/GB2000186A/en not_active Withdrawn
- 1978-06-13 JP JP53071398A patent/JPS592276B2/ja not_active Expired
- 1978-06-13 ES ES470729A patent/ES470729A1/es not_active Expired
- 1978-06-14 AU AU37088/78A patent/AU525724B2/en not_active Expired
- 1978-06-14 CA CA305,453A patent/CA1103157A/en not_active Expired
- 1978-06-14 BE BE188549A patent/BE868099A/xx not_active IP Right Cessation
- 1978-06-14 DE DE19782826075 patent/DE2826075A1/de active Granted
- 1978-06-14 IT IT7824577A patent/IT1096742B/it active
- 1978-06-14 CH CH649278A patent/CH640735A5/de not_active IP Right Cessation
- 1978-06-14 NO NO782081A patent/NO782081L/no unknown
- 1978-06-14 IL IL54908A patent/IL54908A/xx unknown
- 1978-06-14 DK DK267378A patent/DK267378A/da not_active Application Discontinuation
- 1978-06-14 LU LU79812A patent/LU79812A1/de unknown
- 1978-06-15 PL PL20765278A patent/PL207652A1/xx unknown
- 1978-06-15 NL NL7806471A patent/NL7806471A/xx not_active Application Discontinuation
-
1982
- 1982-11-12 JP JP57198816A patent/JPS58101688A/ja active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0014519A3 (en) * | 1979-01-09 | 1981-01-07 | National Research Development Corporation | Cell lines, process for preparing them and process for producing antibodies |
| EP0027657A3 (en) * | 1979-10-22 | 1981-10-28 | The Massachusetts General Hospital | Process for producing antibodies to hepatitis virus and cell lines therefor |
| EP0038642A1 (en) * | 1980-04-09 | 1981-10-28 | National Research Development Corporation | A monoclonal antibody against hepatitis B and its production, a hybridoma producing the monoclonal antibody and compositions containing it, the propagation of the hybridoma and the monoclonal antibody for use as an antiviral agent against hepatitus B and in isolating hepatitus b surface antigen from a sample |
| EP0232921A3 (en) * | 1980-04-09 | 1987-10-07 | National Research Development Corporation | Monoclonal antibodies against hepatitis b virus |
| US5204095A (en) * | 1980-04-09 | 1993-04-20 | National Research Development Corporation | Monoclonal antibodies against hepatitis B virus |
| US4608337A (en) * | 1980-11-07 | 1986-08-26 | The Wistar Institute | Human hybridomas and the production of human monoclonal antibodies by human hybridomas |
| US4883752A (en) * | 1984-10-26 | 1989-11-28 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Method for preparing monoclonal antibody to Hbsag |
Also Published As
| Publication number | Publication date |
|---|---|
| IT1096742B (it) | 1985-08-26 |
| PL207652A1 (pl) | 1979-06-04 |
| IL54908A (en) | 1982-01-31 |
| AU3708878A (en) | 1979-12-20 |
| NO782081L (no) | 1978-12-15 |
| FR2394607A1 (fr) | 1979-01-12 |
| AU525724B2 (en) | 1982-11-25 |
| FI64952B (fi) | 1983-10-31 |
| CH640735A5 (de) | 1984-01-31 |
| FI64952C (fi) | 1984-02-10 |
| JPS58101688A (ja) | 1983-06-16 |
| DE2826075A1 (de) | 1979-02-15 |
| DK267378A (da) | 1978-12-16 |
| FI781818A7 (fi) | 1978-12-16 |
| CA1103157A (en) | 1981-06-16 |
| ES470729A1 (es) | 1979-01-16 |
| IT7824577A0 (it) | 1978-06-14 |
| BE868099A (fr) | 1978-10-02 |
| FR2394607B1 (enrdf_load_stackoverflow) | 1983-12-30 |
| DE2826075C2 (enrdf_load_stackoverflow) | 1987-08-06 |
| SE7806729L (sv) | 1978-12-16 |
| ZA783261B (en) | 1979-06-27 |
| LU79812A1 (de) | 1978-12-07 |
| IL54908A0 (en) | 1978-08-31 |
| JPS5417185A (en) | 1979-02-08 |
| JPS592276B2 (ja) | 1984-01-18 |
| NL7806471A (nl) | 1978-12-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB2000186A (en) | Method of producing antibodies in vitro | |
| DE3065072D1 (en) | Process for producing antibodies to hepatitis virus and cell lines therefor | |
| EP0014519A3 (en) | Cell lines, process for preparing them and process for producing antibodies | |
| DK95687A (da) | Fremgangsmaade til chargevis dyrkning af animalske celler | |
| EP0182467A3 (en) | Human hybridoma fusion partner for production of human monoclonal antibodies | |
| PH16656A (en) | Monoclonal antibody to human helper t cells and methods of preparing same | |
| PH16642A (en) | Complement-fixing monoclonal antibody to human t cells,and methods of preparing same | |
| DE3883803D1 (de) | Monoklonale Antikörper gegen melanoma-assoziierte Antigene, Hybridzellinien, die diese Antikörper produzieren, und ihre Verwendung. | |
| PT72143A (en) | Hybrid cell line for producing complement-fixing monoclonal antibody to human supressor t cells antibody and methods | |
| IE46215L (en) | Gamma-globulins, immune nucleic acids and immune dialysates. | |
| PT71814B (en) | Hybrid cell line for producing monoclonal antibody to human cytotoxic and supressor t cells antibody and methods | |
| NO159887C (no) | Monoklonalt antistoff. | |
| YU43224B (en) | Method of obtaining monoclonal antibodies | |
| ES8106552A1 (es) | Un procedimiento para la propagacion del virus de la hepati-tis a humana | |
| GB2021754B (en) | Method and instalaltion for production and distribution ofthermal energy with compensated transfers to the geothermal table | |
| ES496445A0 (es) | Un metodo de preparacion de antigeno superficial de la hepa-titis b | |
| KR850006705A (ko) | 항파상풍항체 생산 인체-인체 하이브리도마의 제조방법 | |
| DE2963410D1 (en) | Process for obtaining murine immunglobulin-e antibodies, hybrid cell lines used in the process and the process for preparing them, application of the immunglobulin-e antibodies so obtained | |
| KR860009125A (ko) | 모노클로날 항체의 제조 방법 | |
| JPS643199A (en) | Monoclonal antibody | |
| ZA805743B (en) | Hybrid cell line for producing monoclonal antibody to human cytotoxic and supressor t cells, antibody, and methods | |
| SE8401946D0 (sv) | Antibody to human prostate cancer | |
| HRP940809B1 (en) | Hybrid cell line for producing complement-fixing monoclonal antibody to human t cells, antibody and methods | |
| HRP940822B1 (en) | Hybrid cell line for producing complement-fixing monoclonal antibody to human supressor t cells, antibody and methods | |
| JPS53112532A (en) | Preparation of heat collecting plate for sunbeams |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |