GB182986A - Manufacture of amino-derivatives of hydrogenated cinchona alkaloids and their derivatives - Google Patents

Manufacture of amino-derivatives of hydrogenated cinchona alkaloids and their derivatives

Info

Publication number
GB182986A
GB182986A GB1300421A GB1300421A GB182986A GB 182986 A GB182986 A GB 182986A GB 1300421 A GB1300421 A GB 1300421A GB 1300421 A GB1300421 A GB 1300421A GB 182986 A GB182986 A GB 182986A
Authority
GB
United Kingdom
Prior art keywords
derivatives
amino
hydrogenated
manufacture
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1300421A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MAXIMILIAN NIERENSTEIN
Tronox Pigment UK Ltd
Original Assignee
MAXIMILIAN NIERENSTEIN
Cristal Pigment UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MAXIMILIAN NIERENSTEIN, Cristal Pigment UK Ltd filed Critical MAXIMILIAN NIERENSTEIN
Priority to GB1300421A priority Critical patent/GB182986A/en
Publication of GB182986A publication Critical patent/GB182986A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Amino derivatives of hydrocinchona alkaloids are obtained by reducing the corresponding nitro compounds in neutral or nearly neutral solution. Suitable reducing-agents are metals in the presence of a solution of a salt, for example zinc or iron in presence of ammonium sulphate, tin and an ammonium salt, and hydrogen sulphide; the nitro compound may be dissolved in alcohol, or dissolved in water as a salt. In an example nitrohydroquinine hydrochloride is reduced with iron filings and ammonium sulphate solution at 100 DEG C.
GB1300421A 1921-05-06 1921-05-06 Manufacture of amino-derivatives of hydrogenated cinchona alkaloids and their derivatives Expired GB182986A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1300421A GB182986A (en) 1921-05-06 1921-05-06 Manufacture of amino-derivatives of hydrogenated cinchona alkaloids and their derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1300421A GB182986A (en) 1921-05-06 1921-05-06 Manufacture of amino-derivatives of hydrogenated cinchona alkaloids and their derivatives

Publications (1)

Publication Number Publication Date
GB182986A true GB182986A (en) 1922-07-20

Family

ID=10015059

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1300421A Expired GB182986A (en) 1921-05-06 1921-05-06 Manufacture of amino-derivatives of hydrogenated cinchona alkaloids and their derivatives

Country Status (1)

Country Link
GB (1) GB182986A (en)

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