GB1583034A - Coating pharmaceutical cores - Google Patents
Coating pharmaceutical cores Download PDFInfo
- Publication number
- GB1583034A GB1583034A GB1258477A GB1258477A GB1583034A GB 1583034 A GB1583034 A GB 1583034A GB 1258477 A GB1258477 A GB 1258477A GB 1258477 A GB1258477 A GB 1258477A GB 1583034 A GB1583034 A GB 1583034A
- Authority
- GB
- United Kingdom
- Prior art keywords
- copolymer
- weight
- coating
- water
- aqueous solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000576 coating method Methods 0.000 title claims description 30
- 239000011248 coating agent Substances 0.000 title claims description 22
- 229920001577 copolymer Polymers 0.000 claims abstract description 33
- 239000007864 aqueous solution Substances 0.000 claims abstract description 19
- 239000008199 coating composition Substances 0.000 claims abstract description 10
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims abstract description 9
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 38
- 238000000034 method Methods 0.000 claims description 32
- 229910021529 ammonia Inorganic materials 0.000 claims description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- LDHQCZJRKDOVOX-NSCUHMNNSA-N crotonic acid Chemical compound C\C=C\C(O)=O LDHQCZJRKDOVOX-NSCUHMNNSA-N 0.000 claims description 13
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims description 11
- LDHQCZJRKDOVOX-UHFFFAOYSA-N trans-crotonic acid Natural products CC=CC(O)=O LDHQCZJRKDOVOX-UHFFFAOYSA-N 0.000 claims description 11
- 229920000642 polymer Polymers 0.000 claims description 10
- 238000005507 spraying Methods 0.000 claims description 9
- 238000009501 film coating Methods 0.000 claims description 7
- 239000007888 film coating Substances 0.000 claims description 7
- 229920003176 water-insoluble polymer Polymers 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 4
- 229920003169 water-soluble polymer Polymers 0.000 claims description 4
- 239000000178 monomer Substances 0.000 abstract description 2
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract description 2
- 229920002554 vinyl polymer Polymers 0.000 abstract description 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000002762 monocarboxylic acid derivatives Chemical class 0.000 abstract 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- 239000000725 suspension Substances 0.000 description 8
- 239000006185 dispersion Substances 0.000 description 4
- 239000000454 talc Substances 0.000 description 4
- 229910052623 talc Inorganic materials 0.000 description 4
- 239000004408 titanium dioxide Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 3
- 239000000049 pigment Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000002585 base Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 210000004051 gastric juice Anatomy 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 239000003125 aqueous solvent Substances 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000012674 dispersion polymerization Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 230000020477 pH reduction Effects 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229940068918 polyethylene glycol 400 Drugs 0.000 description 1
- 239000003505 polymerization initiator Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762612889 DE2612889B1 (de) | 1976-03-26 | 1976-03-26 | UEberzugsmittel fuer Arzneiformlinge |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1583034A true GB1583034A (en) | 1981-01-21 |
Family
ID=5973492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1258477A Expired GB1583034A (en) | 1976-03-26 | 1977-03-25 | Coating pharmaceutical cores |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS52117415A (enrdf_load_stackoverflow) |
| CH (1) | CH631620A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2612889B1 (enrdf_load_stackoverflow) |
| FR (1) | FR2345145A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1583034A (enrdf_load_stackoverflow) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4556552A (en) * | 1983-09-19 | 1985-12-03 | Colorcon, Inc. | Enteric film-coating compositions |
| CH666405A5 (de) * | 1985-06-24 | 1988-07-29 | Ciba Geigy Ag | Feste, haltbare darreichungsformen mit elastischem filmueberzug. |
| DE19709532A1 (de) * | 1997-03-10 | 1998-09-17 | Basf Ag | Verwendung von redispergierbaren Polymerpulvern oder Polymergranulaten zum Überziehen von pharmazeutischen oder agrochemischen Darreichungsformen |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE644759C (de) * | 1932-11-23 | 1937-05-12 | I G Farbenindustrie Akt Ges | Verfahren zum UEberziehen von Arzneiformen mit gegen Magensaeure und Magenfermente bestaendigen UEberzuegen |
| DE859931C (de) * | 1944-05-24 | 1952-12-18 | Roehm & Haas G M B H | Galenische Praeparate |
| NL297357A (enrdf_load_stackoverflow) * | 1962-08-31 | |||
| DE2031871C3 (de) * | 1970-06-27 | 1974-06-27 | Roehm Gmbh, 6100 Darmstadt | Überzugsmasse für Arzneiformen |
| BE785702A (fr) * | 1971-07-14 | 1972-10-16 | Roehm Gmbh | Produits de revetement de formes medicamenteuses et leur utilisation |
| FR2211213B1 (enrdf_load_stackoverflow) * | 1972-12-26 | 1976-04-23 | Montagne Noire Prod Chim | |
| JPS517116A (en) * | 1974-06-11 | 1976-01-21 | Shinetsu Chemical Co | Choyoseihifukuyakuzaino seizohoho |
-
1976
- 1976-03-26 DE DE19762612889 patent/DE2612889B1/de active Granted
-
1977
- 1977-03-22 FR FR7708470A patent/FR2345145A1/fr active Granted
- 1977-03-23 CH CH369977A patent/CH631620A5/de not_active IP Right Cessation
- 1977-03-25 GB GB1258477A patent/GB1583034A/en not_active Expired
- 1977-03-26 JP JP3283077A patent/JPS52117415A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2345145B1 (enrdf_load_stackoverflow) | 1981-10-23 |
| DE2612889C2 (enrdf_load_stackoverflow) | 1978-05-03 |
| FR2345145A1 (fr) | 1977-10-21 |
| DE2612889B1 (de) | 1977-09-01 |
| JPS52117415A (en) | 1977-10-01 |
| CH631620A5 (en) | 1982-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4140982B2 (ja) | 薬剤形状物用被覆剤及び結合剤及び薬剤形状物 | |
| EP0058765B1 (de) | In Magensaft lösliche oder quellbare Überzugsmasse und ihre Verwendung in einem Verfahren zum Überziehen von Arzneiformen | |
| US4462839A (en) | Enteric coating for pharmaceutical dosage forms | |
| EP0545209B1 (de) | Redispergierbares Dispersionspulver aus N-Vinylpyrrolidon-Vinylacetat-Copolymerisat, dessen Herstellung und Verwendung | |
| US4421881A (en) | Nitrocellulose lacquer composition containing gelatin and acrylic copolymers | |
| HUT61790A (en) | Film forming product suitqble for coating solid forms and process for producing same | |
| DE2135073C3 (de) | Überzugsmittel für Arzneiformen | |
| HU204188B (en) | Process for coating pharmaceutical products | |
| DE69600226T2 (de) | Wässrige Zubereitung zur Plege und/oder Fixierung von Haaren enthaltend ein im wässrigen Milieu lösliches oder dispergierbares filmbildendes Acryloligomer sowie deren Verwendungen | |
| HU203968B (en) | Aqueous dispersions for coating drug forms | |
| NL178883B (nl) | Werkwijze voor het bereiden van een bekledingspreparaat, alsmede bekleed voorwerp verkregen onder toepassing van een dergelijk preparaat. | |
| DD207150A5 (de) | Verfahren zum ueberziehen von arzneiformen mittels eines in wasser dispergierten ueberzugsmittels | |
| EP0181515A2 (de) | Verfahren zur Herstellung einer wässrigen Überzugsmitteldispersion und ihre Verwendung zum Überziehen von Arzneimitteln | |
| CZ297271B6 (cs) | Suchá povlaková hmota pro výrobu filmu zabranujícímu prístupu vlhkosti, zpusob a tvorba povlaku | |
| KR100192154B1 (ko) | Ph-민감성 중합체로 활성 성분을 코우팅하는 방법 | |
| US3275518A (en) | Tablet coating | |
| GB1583034A (en) | Coating pharmaceutical cores | |
| DE69325501T2 (de) | Nagellack | |
| US10113050B2 (en) | Powdery or granulated composition comprising a copolymer, a dicarboxylic acid and a fatty monocarboxylic acid | |
| Chang et al. | Preparation and evaluation of shellac pseudolatex as an aqueous enteric coating system for pellets | |
| EP0061348A1 (en) | Nitrocellulose lacquer composition containing gelatin and acrylic copolymers | |
| EP0787480A1 (de) | Kosmetische Mittel, die sulfonatgruppentragende Polyamide enthalten | |
| DE2316561A1 (de) | Vinylestercopolymerisate und ihre verwendung in haarfestigern | |
| JPS611624A (ja) | 医薬製剤の被覆法 | |
| US4456628A (en) | Process for film-coating a particulate solid, and emulsions for conducting the process |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
| 746 | Register noted 'licences of right' (sect. 46/1977) | ||
| 747B | Proceeding under sect. 47(1) patents act 1977 | ||
| 747C | Notice that the entry in the register 'licence of right' was cancelled (sect. 47/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19930325 |