GB1538284A - 2-oxo-imidazolidine(-yl-carbonyl or thiocarbonylamino)-acetamido penicillins and cephalosporins - Google Patents

2-oxo-imidazolidine(-yl-carbonyl or thiocarbonylamino)-acetamido penicillins and cephalosporins

Info

Publication number
GB1538284A
GB1538284A GB2584476A GB2584476A GB1538284A GB 1538284 A GB1538284 A GB 1538284A GB 2584476 A GB2584476 A GB 2584476A GB 2584476 A GB2584476 A GB 2584476A GB 1538284 A GB1538284 A GB 1538284A
Authority
GB
Grant status
Application
Patent type
Prior art keywords
compounds
formula
acid
obtained
used
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2584476A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom
    • C07D233/38One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of products other than chlorine, adipic acid, caprolactam, or chlorodifluoromethane, e.g. bulk or fine chemicals or pharmaceuticals
    • Y02P20/55Synthetic design, e.g. reducing the use of auxiliary or protecting groups

Abstract

The title compounds correspond to the formula I; the symbols used are defined in Claim 1. The compounds are obtained by acylation of the optionally silylated amino group of the antibiotic derivatives of the formula II with a derivative of a carboxylic acid or thiocarboxylic acid of the formula III to form a -CE-NH linkage (E = oxygen or sulphur). Protective groups which are present are subsequently eliminated, and the beta -lactam compounds are finally obtained as free acids or as non-toxic salts. The compounds belong to the penicillin and cephalosporin series and can accordingly be used as antibiotics and as animal feed additives. They have a broad spectrum of action while being well tolerated. <IMAGE>
GB2584476A 1975-06-24 1976-06-22 2-oxo-imidazolidine(-yl-carbonyl or thiocarbonylamino)-acetamido penicillins and cephalosporins Expired GB1538284A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE19752528078 DE2528078A1 (en) 1975-06-24 1975-06-24 Alpha-(imidazolidinone carbonylamino) penicillins - and cephalosporins, antibacterials useful e.g. as feed additives
DE19752548663 DE2548663A1 (en) 1975-10-30 1975-10-30 Alpha-(imidazolidinone carbonylamino) penicillins - and cephalosporins, antibacterials useful e.g. as feed additives

Publications (1)

Publication Number Publication Date
GB1538284A true true GB1538284A (en) 1979-01-17

Family

ID=25769060

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2584476A Expired GB1538284A (en) 1975-06-24 1976-06-22 2-oxo-imidazolidine(-yl-carbonyl or thiocarbonylamino)-acetamido penicillins and cephalosporins

Country Status (8)

Country Link
JP (1) JPS525789A (en)
DK (1) DK281276A (en)
ES (1) ES449140A1 (en)
FI (1) FI761807A (en)
FR (1) FR2316940B1 (en)
GB (1) GB1538284A (en)
LU (1) LU75217A1 (en)
NL (1) NL7606789A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6234512Y2 (en) * 1982-11-30 1987-09-03

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2407715C2 (en) * 1974-02-18 1982-12-02 Bayer Ag, 5090 Leverkusen, De
GB1508064A (en) * 1974-05-09 1978-04-19 Toyama Chemical Co Ltd Amino acid derivatives

Also Published As

Publication number Publication date Type
NL7606789A (en) 1976-12-28 application
FR2316940B1 (en) 1978-12-15 grant
ES449140A1 (en) 1977-07-16 application
DK281276A (en) 1976-12-25 application
JPS525789A (en) 1977-01-17 application
FR2316940A1 (en) 1977-02-04 application
FI761807A (en) 1976-12-25 application
LU75217A1 (en) 1977-03-15 application

Similar Documents

Publication Publication Date Title
US4008246A (en) Aminothiazole derivatives
US3708479A (en) Acyloxymethyl esters of alpha-ureidocyclo-hexadie nylalkylene-cephalosporins
GB1073530A (en) Process for the preparation of cephalosporins
GB1342241A (en) Cephalosporin compounds
US3345368A (en) Substituted 7-acetylamino cephalosporanic acids
JPS6041682A (en) Novel cephalosporin compound and its preparation
US3741962A (en) Alpha-thioureidocephalosporanic acid compounds
FR2191556A5 (en) N-Acylampicillins - with broad-spectrum antibacterial activity prepd. by acylation with naphthyridine carboxylic acids
GB1492528A (en) Pyrazinyl piperazine derivatives
US3993646A (en) Process for the ring expansion of penicillins to cephalosporin compounds
JPS5732290A (en) Novel penicillin derivative and its preparation
US3297692A (en) 7-alkylmercaptoacetamidocephalosporanic acid
GB1067965A (en) Penicillins, esters, amides and salts thereof
US4357331A (en) 7αMethoxycephalosporin derivatives
EP0025857A1 (en) Organic sulfoxides having a latent allyl group, process for preparing the same and pharmaceutical antibacterial composition comprising the same
US4160830A (en) Cephalosporins
GB1250611A (en)
US4342758A (en) Allylsulfoxide enzyme inhibitors
US4065619A (en) 7-(α-Sulfoacylamido)cephalosporins
JPS6011490A (en) Beta-lactam derivative
US3454557A (en) 6-(alpha-guanidino acylamino)-penicillanic acid compounds
Nagarajan et al. 3-Cephen chromophore
GB1508071A (en) Cephalosporins and process for producing the same
JPS6251688A (en) Novel cephalosporin compound
GB1081093A (en) Improvements in or relating to 6-[d(-)-alpha-(amino-phenylacetamido)]-penicillanic acid derivatives

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee