GB1510664A - Bone-seeking technetium-99m imidodiphosphonate complex - Google Patents
Bone-seeking technetium-99m imidodiphosphonate complexInfo
- Publication number
- GB1510664A GB1510664A GB41817/75A GB4181775A GB1510664A GB 1510664 A GB1510664 A GB 1510664A GB 41817/75 A GB41817/75 A GB 41817/75A GB 4181775 A GB4181775 A GB 4181775A GB 1510664 A GB1510664 A GB 1510664A
- Authority
- GB
- United Kingdom
- Prior art keywords
- complex
- imidodiphosphonate
- technetium
- imidodiphosphonic
- seeking
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GNGSOPFGGKKDQP-UHFFFAOYSA-N (phosphonoamino)phosphonic acid Chemical compound OP(O)(=O)NP(O)(O)=O GNGSOPFGGKKDQP-UHFFFAOYSA-N 0.000 title abstract 4
- GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 title abstract 2
- 229940056501 technetium 99m Drugs 0.000 title abstract 2
- 239000012216 imaging agent Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 239000000941 radioactive substance Substances 0.000 abstract 1
- IUTCEZPPWBHGIX-UHFFFAOYSA-N tin(2+) Chemical compound [Sn+2] IUTCEZPPWBHGIX-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/582,176 US3974268A (en) | 1975-05-30 | 1975-05-30 | Bone-seeking technetium-99m imidodiphosphonate complex |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1510664A true GB1510664A (en) | 1978-05-10 |
Family
ID=24328131
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB41817/75A Expired GB1510664A (en) | 1975-05-30 | 1975-10-13 | Bone-seeking technetium-99m imidodiphosphonate complex |
| GB25844/77A Expired GB1510665A (en) | 1975-05-30 | 1975-10-13 | Stannous imidodiphosphonate complex |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB25844/77A Expired GB1510665A (en) | 1975-05-30 | 1975-10-13 | Stannous imidodiphosphonate complex |
Country Status (5)
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3974268A (en) * | 1975-05-30 | 1976-08-10 | Research Corporation | Bone-seeking technetium-99m imidodiphosphonate complex |
| DE2543350C2 (de) * | 1975-09-29 | 1984-10-11 | Henkel KGaA, 4000 Düsseldorf | Präparate zur Herstellung von ↑9↑↑9↑↑m↑ Technetium-Radiodiagnostika |
| DE2543349C2 (de) * | 1975-09-29 | 1984-05-10 | Henkel KGaA, 4000 Düsseldorf | Preaparate zur herstellung von99m technetium-radiagnostica |
| CA1078731A (en) * | 1976-12-16 | 1980-06-03 | Charles E. Frosst And Co. | Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid) |
| US4897255A (en) * | 1985-01-14 | 1990-01-30 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
| US5175343A (en) * | 1985-01-14 | 1992-12-29 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
| JP2785025B2 (ja) * | 1985-03-19 | 1998-08-13 | ランデル・エル・ミルズ | 診断と選択的組織壊死を与える装置 |
| JPS61282931A (ja) * | 1985-06-10 | 1986-12-13 | Hitachi Ltd | 初期マイクロプログラム・ロ−ド方式 |
| US5202451A (en) * | 1988-02-17 | 1993-04-13 | Neorx Corporation | Anchimeric radiometal chelating compounds |
| US5089249A (en) * | 1988-06-10 | 1992-02-18 | Neorx Corporation | Conjugates for bone imaging and bone cancer therapy |
| US5202109A (en) * | 1988-06-10 | 1993-04-13 | Neorx Corporation | Conjugates for bone imaging and bone cancer therapy |
| JPH0255064U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1988-10-12 | 1990-04-20 | ||
| US5192526A (en) * | 1989-05-02 | 1993-03-09 | Mallinckrodt Medical, Inc. | Kit for preparation of rhenium therapeutic agents for bone cancer without purification |
| JPH031063A (ja) * | 1989-05-26 | 1991-01-07 | Toyo Eng Works Ltd | 人工降雪装置 |
| JP2003501488A (ja) * | 1999-06-11 | 2003-01-14 | ネオルックス コーポレイション | 骨髄抑制のための高投与量放射性核種錯体 |
| US7094885B2 (en) * | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
| US6548042B2 (en) * | 2000-08-07 | 2003-04-15 | Arstad Erik | Bis-phosphonate compounds |
| WO2002062398A2 (en) | 2001-01-08 | 2002-08-15 | Neorx Corporation | Radioactively labelled conjugates of phosphonates |
| US6776977B2 (en) * | 2001-01-09 | 2004-08-17 | Bristol-Myers Squibb Pharma Company | Polypodal chelants for metallopharmaceuticals |
| WO2021032784A1 (en) | 2019-08-19 | 2021-02-25 | Nuclear Research And Consultancy Group | Platinum isotope combined with bone-targeting agents for use in anticancer drugs |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3125412A (en) * | 1964-03-17 | Process ok the manufacture of alkali | ||
| DE1015777B (de) * | 1956-10-16 | 1957-09-19 | Benckiser Gmbh Joh A | Verfahren zur Herstellung von Phosphamprodukten |
| US3735001A (en) * | 1972-05-24 | 1973-05-22 | Atomic Energy Commission | Technetium bone scanning medium |
| US3974268A (en) * | 1975-05-30 | 1976-08-10 | Research Corporation | Bone-seeking technetium-99m imidodiphosphonate complex |
-
1975
- 1975-05-30 US US05/582,176 patent/US3974268A/en not_active Expired - Lifetime
- 1975-10-13 GB GB41817/75A patent/GB1510664A/en not_active Expired
- 1975-10-13 GB GB25844/77A patent/GB1510665A/en not_active Expired
- 1975-10-23 DE DE2547376A patent/DE2547376C2/de not_active Expired
- 1975-10-23 DE DE2560627A patent/DE2560627C2/de not_active Expired
- 1975-10-28 JP JP50129763A patent/JPS5835487B2/ja not_active Expired
- 1975-11-14 CA CA 239651 patent/CA1069914A/en not_active Expired
-
1982
- 1982-10-18 JP JP57182666A patent/JPS58113137A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS51144737A (en) | 1976-12-13 |
| US3974268A (en) | 1976-08-10 |
| GB1510665A (en) | 1978-05-10 |
| CA1069914A (en) | 1980-01-15 |
| DE2547376C2 (de) | 1987-01-29 |
| DE2560627C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1987-08-06 |
| JPS5835487B2 (ja) | 1983-08-03 |
| JPS58113137A (ja) | 1983-07-05 |
| JPS6140652B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1986-09-10 |
| DE2547376A1 (de) | 1976-12-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1510664A (en) | Bone-seeking technetium-99m imidodiphosphonate complex | |
| HU912011D0 (en) | Radioactive medical preparations and process for their production and portioning | |
| GB1489330A (en) | Stable diagnostic reagents | |
| US3961038A (en) | Process for the manufacture of injectable preparations of Tc99m and/or In113m and apparatus for carrying out the process | |
| FR2285857B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| GB1530106A (en) | Stannous pyrophosphate technetium-99m compositions | |
| JPS5569517A (en) | Labelling preparation for labelling of erythrocytes with radio-active technetium | |
| GB1541070A (en) | Stable radiographic scanning agents | |
| PH20604A (en) | Improvements in or relating to indanyl derivatives and pharmaceutical preparations containing them | |
| GB1318813A (en) | Radio-active labelled albumin preparation | |
| GB1469075A (en) | Method of tagging vehicular substances with 99mm technetium | |
| JPS5750928A (en) | Diagnostic agent for scanning bone | |
| GB1535847A (en) | Technetium-99m labelled tin colloid for body scanning | |
| JPS52105222A (en) | Stabilized alcoholic solution of reducible salt composition for making radioactive isotope indication scanning agent technetium 999m colloid for liver scanning and method of making same | |
| ES375358A1 (es) | Un procedimiento para preparar un coloide de azufre y tec- necio 99m. | |
| US3928552A (en) | Hepato-biliary radiopharmaceutical comprising 2-mercaptoisobutyric acid chelating reduced technetium-99m | |
| GB1320626A (en) | Radioactive labelled preparations | |
| GB1361988A (en) | Technetium-99m generators | |
| GB1404252A (en) | 99m-technetium labelled tin colloid radiopharmaceuticals | |
| GB1429549A (en) | Bone-seeking technetium-99m complex | |
| GB1303761A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| JPS5759816A (en) | Production of radioactive medicine composition based on technetium-99m and drug therefor | |
| GB1453291A (en) | Radiactive generator with permeable closure | |
| GB1435295A (en) | Bone seeking technetium-99m complex | |
| Marchi et al. | Technetium complexes with ligands of pharmacological interest |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |