GB1469430A - Daunomycin derivatives - Google Patents
Daunomycin derivativesInfo
- Publication number
- GB1469430A GB1469430A GB5579674A GB5579674A GB1469430A GB 1469430 A GB1469430 A GB 1469430A GB 5579674 A GB5579674 A GB 5579674A GB 5579674 A GB5579674 A GB 5579674A GB 1469430 A GB1469430 A GB 1469430A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- dec
- formula
- compound
- daunomycin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical class O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5579674A GB1469430A (en) | 1974-12-24 | 1974-12-24 | Daunomycin derivatives |
| US05/637,170 US4024224A (en) | 1974-12-24 | 1975-12-03 | 14-Aminodaunomycins, their preparation and use |
| DE2557537A DE2557537C3 (de) | 1974-12-24 | 1975-12-19 | Daunomycinderivate, Verfahren zu deren Herstellung und pharmazeutisches Mittel |
| FR7539329A FR2295756A1 (fr) | 1974-12-24 | 1975-12-22 | Nouveaux derives de daunomycine et leur procede de preparation |
| JP50153214A JPS5840558B2 (ja) | 1974-12-24 | 1975-12-22 | ダウノマイシンユウドウタイノセイホウ |
| HU75FA984A HU173853B (hu) | 1974-12-24 | 1975-12-22 | Sposob poluchenija proizvodnykh daunomicina |
| CH1672375A CH602784A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-12-24 | 1975-12-23 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5579674A GB1469430A (en) | 1974-12-24 | 1974-12-24 | Daunomycin derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1469430A true GB1469430A (en) | 1977-04-06 |
Family
ID=10474914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5579674A Expired GB1469430A (en) | 1974-12-24 | 1974-12-24 | Daunomycin derivatives |
Country Status (7)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES444380A1 (es) * | 1976-01-16 | 1977-06-16 | Gosalvez Mario | Un procedimiento para preparar derivados metalicos antraci- clinicos. |
| GB1518390A (en) * | 1976-03-30 | 1978-07-19 | Farmaceutici Italia | Doxorubicin thioesters |
| RU977462C (ru) | 1980-03-24 | 1995-06-27 | Отделение Института химической физики АН СССР | 13-(1-оксил-2,2,6,6-тетраметилпиперилиденил-4)гидразон рубомицина хлоргидрат с парамагнитным центром, проявляющий противоопухолевую активность, и способ его получения |
| GB9416007D0 (en) * | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Anthracyclinone derivatives |
| US10907145B2 (en) * | 2017-03-08 | 2021-02-02 | Arizona Board Of Regents On Behalf Of Arizona State University | Chemotherapeutic drug-conjugated resins and their preferential binding of methylated DNA |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3133912A (en) * | 1957-03-14 | 1964-05-19 | Benckiser Gmbh Joh A | Reaction product of amino carbohy-drates with therapeutically effective amino compounds |
| US3037015A (en) * | 1958-07-19 | 1962-05-29 | Benckiser Gmbh Joh A | Therapeutically valuable compounds and process of producing same |
| US3957755A (en) * | 1967-10-18 | 1976-05-18 | Rhone-Poulenc S.A. | Naphthacene derivatives |
| US3803124A (en) * | 1968-04-12 | 1974-04-09 | Farmaceutici It Soc | Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives |
-
1974
- 1974-12-24 GB GB5579674A patent/GB1469430A/en not_active Expired
-
1975
- 1975-12-03 US US05/637,170 patent/US4024224A/en not_active Expired - Lifetime
- 1975-12-19 DE DE2557537A patent/DE2557537C3/de not_active Expired
- 1975-12-22 FR FR7539329A patent/FR2295756A1/fr active Granted
- 1975-12-22 JP JP50153214A patent/JPS5840558B2/ja not_active Expired
- 1975-12-22 HU HU75FA984A patent/HU173853B/hu not_active IP Right Cessation
- 1975-12-23 CH CH1672375A patent/CH602784A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2557537C3 (de) | 1979-10-11 |
| CH602784A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-08-15 |
| HU173853B (hu) | 1979-09-28 |
| JPS5840558B2 (ja) | 1983-09-06 |
| DE2557537A1 (de) | 1976-07-08 |
| DE2557537B2 (de) | 1979-02-15 |
| FR2295756A1 (fr) | 1976-07-23 |
| JPS51125268A (en) | 1976-11-01 |
| US4024224A (en) | 1977-05-17 |
| FR2295756B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-07-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1345880A (en) | Pyridazine derivatives | |
| GB1351501A (en) | Adenosine derivatives and the production thereof | |
| GB1450010A (en) | Preparation of triamino pyrimidine n-oxides | |
| GB1488692A (en) | Pyrazolo(3,4,6)quinolines | |
| GB1417030A (en) | Lactamimide derivatives | |
| GB1456627A (en) | Pyridobenzodiazepinones | |
| GB1411583A (en) | Aminophenyl-substituted alkyl-heterocyclic derivatives and processes for producing them | |
| GB1469430A (en) | Daunomycin derivatives | |
| GB1367785A (en) | 2-substituted adenosine derivatives and the production thereof | |
| GB1439724A (en) | Berbine derivatives and pharmaceutical compositions containing them | |
| GB1477302A (en) | Triazolo-isoindole and triazolo-isoquinoline derivatives and their manufacture and uses | |
| GB1084150A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| GB1511006A (en) | Pyrazolopyridines | |
| GB1469006A (en) | 2-phenylhydrazinothiazolines or-thiazines and a process for the preparation thereof | |
| GB1394791A (en) | Diphenylalkyllactamimide derivatives | |
| GB1501149A (en) | Isocarbostyril derivatives | |
| GB1514225A (en) | Paracetamol derivatives | |
| GB1338459A (en) | Flavanone derivatives and process for inhibiting growth of microorganisms using such compounds | |
| GB1299566A (en) | Bis-basic ethers of 2,6- and 2,7-dihydroxyanthraquinones | |
| GB1254270A (en) | Benzoxazepine derivatives | |
| GB1392007A (en) | Cycloalkylthiazoles | |
| GB1184826A (en) | Substituted Aryloxy Hydroxy Amines | |
| GB1394184A (en) | 4,5-dihydropyridazine-3 2h- ones | |
| GB1508222A (en) | Derivatives of pyrazolopyridines | |
| GB1472344A (en) | Methylene dibenzocycloheptanes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |