GB1465661A - Stilbene derivatives - Google Patents

Stilbene derivatives

Info

Publication number
GB1465661A
GB1465661A GB2539075A GB2539075A GB1465661A GB 1465661 A GB1465661 A GB 1465661A GB 2539075 A GB2539075 A GB 2539075A GB 2539075 A GB2539075 A GB 2539075A GB 1465661 A GB1465661 A GB 1465661A
Authority
GB
United Kingdom
Prior art keywords
compounds
prepared
alkyl
viii
hydrolysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2539075A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of GB1465661A publication Critical patent/GB1465661A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/194Radicals derived from thio- or thiono carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/794Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring
    • C07C49/796Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/42Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C57/60Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB2539075A 1974-07-16 1975-06-13 Stilbene derivatives Expired GB1465661A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49081299A JPS5111748A (en) 1974-07-16 1974-07-16 Suchirubenjudotaino seizoho

Publications (1)

Publication Number Publication Date
GB1465661A true GB1465661A (en) 1977-02-23

Family

ID=13742501

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2539075A Expired GB1465661A (en) 1974-07-16 1975-06-13 Stilbene derivatives

Country Status (12)

Country Link
JP (1) JPS5111748A (enrdf_load_stackoverflow)
AR (1) AR205387A1 (enrdf_load_stackoverflow)
AU (1) AU470771B2 (enrdf_load_stackoverflow)
CA (1) CA1053257A (enrdf_load_stackoverflow)
CH (1) CH610582A5 (enrdf_load_stackoverflow)
DE (1) DE2531456A1 (enrdf_load_stackoverflow)
ES (1) ES439430A1 (enrdf_load_stackoverflow)
FR (1) FR2278332A1 (enrdf_load_stackoverflow)
GB (1) GB1465661A (enrdf_load_stackoverflow)
NL (1) NL7507803A (enrdf_load_stackoverflow)
PH (1) PH11312A (enrdf_load_stackoverflow)
SE (1) SE409452B (enrdf_load_stackoverflow)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684744A (en) * 1984-03-27 1987-08-04 Ciga-Geiby Corporation Stilbene derivatives
EP0150166B1 (en) * 1984-01-19 1988-07-20 Pharmacia Ab Novel arylacitic acid derivatives
WO2001042231A3 (en) * 1999-12-06 2001-11-01 Welichem Biotech Inc Polyhydroxystilbenes and stilbene oxides as antisoriatic agents and protein kinase inhibitors
WO2003043625A1 (en) * 2001-11-20 2003-05-30 Dompe S.P.A. 2-aryl-propionic acids and pharmaceutical compositions containing them
US7321050B2 (en) 1999-12-06 2008-01-22 Welichem Biotech Inc. Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues
EP1216980A4 (en) * 1999-10-01 2010-12-08 Eisai R&D Man Co Ltd CARBOXYLIC ACID DERIVATIVES AND MEDICAMENTS CONTAINING THE SAME
US10426743B2 (en) 2015-05-21 2019-10-01 Dermavant Sciences GmbH Topical pharmaceutical compositions
US10647649B2 (en) 2017-11-10 2020-05-12 Dermavant Sciences GmbH Process for preparing tapinarof
US11497718B2 (en) 2018-11-13 2022-11-15 Dermavant Sciences GmbH Use of tapinarof for the treatment of atopic dermatitis
US11617724B2 (en) 2015-05-21 2023-04-04 Dermavant Sciences GmbH Topical pharmaceutical compositions

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2832213A1 (de) * 1978-07-21 1980-01-31 Bayer Ag Stilbenderivate, verfahren zu ihrer herstellung und ihre verwendung als insektizide
DE2944428C2 (de) * 1979-11-03 1984-08-30 Trützschler GmbH & Co KG, 4050 Mönchengladbach Vorrichtung zur Produktionssteuerung und Bandregulierung einer Karde
FR2492815A1 (fr) * 1980-10-23 1982-04-30 Sori Soc Rech Ind Nouveau derive d'acide cinnamoyl-cinnamique, son procede de preparation et son application en therapeutique

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0150166B1 (en) * 1984-01-19 1988-07-20 Pharmacia Ab Novel arylacitic acid derivatives
US4684744A (en) * 1984-03-27 1987-08-04 Ciga-Geiby Corporation Stilbene derivatives
EP1216980A4 (en) * 1999-10-01 2010-12-08 Eisai R&D Man Co Ltd CARBOXYLIC ACID DERIVATIVES AND MEDICAMENTS CONTAINING THE SAME
WO2001042231A3 (en) * 1999-12-06 2001-11-01 Welichem Biotech Inc Polyhydroxystilbenes and stilbene oxides as antisoriatic agents and protein kinase inhibitors
US7321050B2 (en) 1999-12-06 2008-01-22 Welichem Biotech Inc. Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues
WO2003043625A1 (en) * 2001-11-20 2003-05-30 Dompe S.P.A. 2-aryl-propionic acids and pharmaceutical compositions containing them
AU2002352052B2 (en) * 2001-11-20 2008-09-04 Dompe' Farmaceutici S.P.A. 2-Aryl-propionic acids and pharmaceutical compositions containing them
US8063242B2 (en) 2001-11-20 2011-11-22 Dompe Pha.R.Ma S.P.A. 2-aryl-propionic acids and pharmaceutical compositions containing them
US10426743B2 (en) 2015-05-21 2019-10-01 Dermavant Sciences GmbH Topical pharmaceutical compositions
US11458108B2 (en) 2015-05-21 2022-10-04 Dermavant Sciences GmbH Topical pharmaceutical compositions
US11612573B2 (en) 2015-05-21 2023-03-28 Dermavant Sciences GmbH Topical pharmaceutical compositions
US11617724B2 (en) 2015-05-21 2023-04-04 Dermavant Sciences GmbH Topical pharmaceutical compositions
US11622945B2 (en) 2015-05-21 2023-04-11 Dermavant Sciences GmbH Topical pharmaceutical compositions
US10647649B2 (en) 2017-11-10 2020-05-12 Dermavant Sciences GmbH Process for preparing tapinarof
US10961175B2 (en) 2017-11-10 2021-03-30 Dermavant Sciences GmbH Process for preparing tapinarof
US11597692B2 (en) 2017-11-10 2023-03-07 Dermavant Sciences GmbH Process for preparing tapinarof
US12275696B2 (en) 2017-11-10 2025-04-15 Dermavant Sciences GmbH Process for preparing tapinarof
US11497718B2 (en) 2018-11-13 2022-11-15 Dermavant Sciences GmbH Use of tapinarof for the treatment of atopic dermatitis
US11938099B2 (en) 2018-11-13 2024-03-26 Dermavant Sciences GmbH Use of tapinarof for the treatment of atopic dermatitis

Also Published As

Publication number Publication date
JPS5227B2 (enrdf_load_stackoverflow) 1977-01-05
AU8215275A (en) 1976-03-25
CA1053257A (en) 1979-04-24
NL7507803A (nl) 1976-01-20
FR2278332B1 (enrdf_load_stackoverflow) 1980-05-16
PH11312A (en) 1977-11-02
ES439430A1 (es) 1977-02-01
AU470771B2 (en) 1976-03-25
CH610582A5 (en) 1979-04-30
SE7508074L (sv) 1976-01-19
AR205387A1 (es) 1976-04-30
JPS5111748A (en) 1976-01-30
DE2531456A1 (de) 1976-02-05
FR2278332A1 (fr) 1976-02-13
SE409452B (sv) 1979-08-20

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee