GB1465661A - Stilbene derivatives - Google Patents
Stilbene derivativesInfo
- Publication number
- GB1465661A GB1465661A GB2539075A GB2539075A GB1465661A GB 1465661 A GB1465661 A GB 1465661A GB 2539075 A GB2539075 A GB 2539075A GB 2539075 A GB2539075 A GB 2539075A GB 1465661 A GB1465661 A GB 1465661A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- prepared
- alkyl
- viii
- hydrolysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/194—Radicals derived from thio- or thiono carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/794—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring
- C07C49/796—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/42—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP49081299A JPS5111748A (en) | 1974-07-16 | 1974-07-16 | Suchirubenjudotaino seizoho |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1465661A true GB1465661A (en) | 1977-02-23 |
Family
ID=13742501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2539075A Expired GB1465661A (en) | 1974-07-16 | 1975-06-13 | Stilbene derivatives |
Country Status (12)
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4684744A (en) * | 1984-03-27 | 1987-08-04 | Ciga-Geiby Corporation | Stilbene derivatives |
| EP0150166B1 (en) * | 1984-01-19 | 1988-07-20 | Pharmacia Ab | Novel arylacitic acid derivatives |
| WO2001042231A3 (en) * | 1999-12-06 | 2001-11-01 | Welichem Biotech Inc | Polyhydroxystilbenes and stilbene oxides as antisoriatic agents and protein kinase inhibitors |
| WO2003043625A1 (en) * | 2001-11-20 | 2003-05-30 | Dompe S.P.A. | 2-aryl-propionic acids and pharmaceutical compositions containing them |
| US7321050B2 (en) | 1999-12-06 | 2008-01-22 | Welichem Biotech Inc. | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues |
| EP1216980A4 (en) * | 1999-10-01 | 2010-12-08 | Eisai R&D Man Co Ltd | CARBOXYLIC ACID DERIVATIVES AND MEDICAMENTS CONTAINING THE SAME |
| US10426743B2 (en) | 2015-05-21 | 2019-10-01 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
| US10647649B2 (en) | 2017-11-10 | 2020-05-12 | Dermavant Sciences GmbH | Process for preparing tapinarof |
| US11497718B2 (en) | 2018-11-13 | 2022-11-15 | Dermavant Sciences GmbH | Use of tapinarof for the treatment of atopic dermatitis |
| US11617724B2 (en) | 2015-05-21 | 2023-04-04 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2832213A1 (de) * | 1978-07-21 | 1980-01-31 | Bayer Ag | Stilbenderivate, verfahren zu ihrer herstellung und ihre verwendung als insektizide |
| DE2944428C2 (de) * | 1979-11-03 | 1984-08-30 | Trützschler GmbH & Co KG, 4050 Mönchengladbach | Vorrichtung zur Produktionssteuerung und Bandregulierung einer Karde |
| FR2492815A1 (fr) * | 1980-10-23 | 1982-04-30 | Sori Soc Rech Ind | Nouveau derive d'acide cinnamoyl-cinnamique, son procede de preparation et son application en therapeutique |
-
1974
- 1974-07-16 JP JP49081299A patent/JPS5111748A/ja active Granted
-
1975
- 1975-01-01 AR AR259394A patent/AR205387A1/es active
- 1975-06-13 GB GB2539075A patent/GB1465661A/en not_active Expired
- 1975-06-17 AU AU82152/75A patent/AU470771B2/en not_active Expired
- 1975-06-26 PH PH17515A patent/PH11312A/en unknown
- 1975-07-01 NL NL7507803A patent/NL7507803A/xx not_active Application Discontinuation
- 1975-07-14 DE DE19752531456 patent/DE2531456A1/de not_active Withdrawn
- 1975-07-15 FR FR7522113A patent/FR2278332A1/fr active Granted
- 1975-07-15 CA CA231,559A patent/CA1053257A/en not_active Expired
- 1975-07-15 CH CH921275A patent/CH610582A5/xx not_active IP Right Cessation
- 1975-07-15 SE SE7508074A patent/SE409452B/xx unknown
- 1975-07-15 ES ES439430A patent/ES439430A1/es not_active Expired
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0150166B1 (en) * | 1984-01-19 | 1988-07-20 | Pharmacia Ab | Novel arylacitic acid derivatives |
| US4684744A (en) * | 1984-03-27 | 1987-08-04 | Ciga-Geiby Corporation | Stilbene derivatives |
| EP1216980A4 (en) * | 1999-10-01 | 2010-12-08 | Eisai R&D Man Co Ltd | CARBOXYLIC ACID DERIVATIVES AND MEDICAMENTS CONTAINING THE SAME |
| WO2001042231A3 (en) * | 1999-12-06 | 2001-11-01 | Welichem Biotech Inc | Polyhydroxystilbenes and stilbene oxides as antisoriatic agents and protein kinase inhibitors |
| US7321050B2 (en) | 1999-12-06 | 2008-01-22 | Welichem Biotech Inc. | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues |
| WO2003043625A1 (en) * | 2001-11-20 | 2003-05-30 | Dompe S.P.A. | 2-aryl-propionic acids and pharmaceutical compositions containing them |
| AU2002352052B2 (en) * | 2001-11-20 | 2008-09-04 | Dompe' Farmaceutici S.P.A. | 2-Aryl-propionic acids and pharmaceutical compositions containing them |
| US8063242B2 (en) | 2001-11-20 | 2011-11-22 | Dompe Pha.R.Ma S.P.A. | 2-aryl-propionic acids and pharmaceutical compositions containing them |
| US10426743B2 (en) | 2015-05-21 | 2019-10-01 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
| US11458108B2 (en) | 2015-05-21 | 2022-10-04 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
| US11612573B2 (en) | 2015-05-21 | 2023-03-28 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
| US11617724B2 (en) | 2015-05-21 | 2023-04-04 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
| US11622945B2 (en) | 2015-05-21 | 2023-04-11 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
| US10647649B2 (en) | 2017-11-10 | 2020-05-12 | Dermavant Sciences GmbH | Process for preparing tapinarof |
| US10961175B2 (en) | 2017-11-10 | 2021-03-30 | Dermavant Sciences GmbH | Process for preparing tapinarof |
| US11597692B2 (en) | 2017-11-10 | 2023-03-07 | Dermavant Sciences GmbH | Process for preparing tapinarof |
| US12275696B2 (en) | 2017-11-10 | 2025-04-15 | Dermavant Sciences GmbH | Process for preparing tapinarof |
| US11497718B2 (en) | 2018-11-13 | 2022-11-15 | Dermavant Sciences GmbH | Use of tapinarof for the treatment of atopic dermatitis |
| US11938099B2 (en) | 2018-11-13 | 2024-03-26 | Dermavant Sciences GmbH | Use of tapinarof for the treatment of atopic dermatitis |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5227B2 (enrdf_load_stackoverflow) | 1977-01-05 |
| AU8215275A (en) | 1976-03-25 |
| CA1053257A (en) | 1979-04-24 |
| NL7507803A (nl) | 1976-01-20 |
| FR2278332B1 (enrdf_load_stackoverflow) | 1980-05-16 |
| PH11312A (en) | 1977-11-02 |
| ES439430A1 (es) | 1977-02-01 |
| AU470771B2 (en) | 1976-03-25 |
| CH610582A5 (en) | 1979-04-30 |
| SE7508074L (sv) | 1976-01-19 |
| AR205387A1 (es) | 1976-04-30 |
| JPS5111748A (en) | 1976-01-30 |
| DE2531456A1 (de) | 1976-02-05 |
| FR2278332A1 (fr) | 1976-02-13 |
| SE409452B (sv) | 1979-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |