GB1452231A - Method and apparatus for detecting and classifying nucleic acid particles - Google Patents

Method and apparatus for detecting and classifying nucleic acid particles

Info

Publication number
GB1452231A
GB1452231A GB2279074A GB2279074A GB1452231A GB 1452231 A GB1452231 A GB 1452231A GB 2279074 A GB2279074 A GB 2279074A GB 2279074 A GB2279074 A GB 2279074A GB 1452231 A GB1452231 A GB 1452231A
Authority
GB
United Kingdom
Prior art keywords
radiation
fluorescent
nucleic acid
filter
optics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2279074A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Block Engineering Inc
Original Assignee
Block Engineering Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Block Engineering Inc filed Critical Block Engineering Inc
Publication of GB1452231A publication Critical patent/GB1452231A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
GB2279074A 1973-07-02 1974-05-22 Method and apparatus for detecting and classifying nucleic acid particles Expired GB1452231A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US375807A US3872312A (en) 1973-07-02 1973-07-02 Method and apparatus for detecting and classifying nucleic acid particles

Publications (1)

Publication Number Publication Date
GB1452231A true GB1452231A (en) 1976-10-13

Family

ID=23482435

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2279074A Expired GB1452231A (en) 1973-07-02 1974-05-22 Method and apparatus for detecting and classifying nucleic acid particles

Country Status (9)

Country Link
US (1) US3872312A (https=)
JP (1) JPS5050093A (https=)
AU (1) AU476320B2 (https=)
CA (1) CA1002343A (https=)
CH (1) CH582882A5 (https=)
DE (1) DE2431203A1 (https=)
FR (1) FR2236180B1 (https=)
GB (1) GB1452231A (https=)
NL (1) NL7407776A (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2196734A (en) * 1986-09-30 1988-05-05 Astromed Ltd Multiple assaying technique

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571388A (en) * 1983-01-24 1986-02-18 Becton Dickinson And Company Detection of reticulocytes
NZ207393A (en) * 1983-08-05 1987-03-31 Neal Lloyd First Staining dna in living cells
SE455646B (sv) * 1984-10-22 1988-07-25 Radians Innova Ab Fluorescensanordning
US4707451A (en) * 1985-09-18 1987-11-17 Becton, Dickinson And Company Detection of reticulocytes
US4957870A (en) * 1985-11-01 1990-09-18 Becton, Dickinson And Company Detection of Reticulocytes, RNA and DNA
DE3677916D1 (de) * 1985-11-01 1991-04-11 Becton Dickinson Co Nachweis von retikulozyten.
US4883867A (en) * 1985-11-01 1989-11-28 Becton, Dickinson And Company Detection of reticulocytes, RNA or DNA
EP0359681B1 (en) * 1988-09-15 1995-11-08 The Board Of Trustees Of The University Of Arkansas Characterization of particles by modulated dynamic light scattering
US5350697A (en) * 1990-08-28 1994-09-27 Akzo N.V. Scattered light detection apparatus
US7241569B2 (en) * 1993-01-18 2007-07-10 Olympus Corporation Method and a device for the evaluation of biopolymer fitness
AU5884394A (en) * 1993-01-18 1994-08-15 Evotec Biosystems Gmbh Method and device for assessing the suitability of biopolymers
AU673245B2 (en) * 1993-02-01 1996-10-31 Seq, Ltd. Methods and apparatus for DNA sequencing
US5382512A (en) * 1993-08-23 1995-01-17 Chiron Corporation Assay device with captured particle reagent
IL113805A0 (en) * 1994-05-23 1995-08-31 Coulter Corp Detection of reticulocytes
US8685711B2 (en) 2004-09-28 2014-04-01 Singulex, Inc. Methods and compositions for highly sensitive detection of molecules
US9040305B2 (en) 2004-09-28 2015-05-26 Singulex, Inc. Method of analysis for determining a specific protein in blood samples using fluorescence spectrometry
CA2709217C (en) 2007-12-19 2021-01-05 Singulex, Inc. Scanning analyzer for single molecule detection and methods of use
EP3256850B1 (en) 2015-02-09 2025-07-09 Slingshot Biosciences, Inc. Hydrogel particles with tunable optical properties and methods for using the same
CN106769709B (zh) * 2016-12-08 2019-03-26 清华大学深圳研究生院 一种基于偏振散射特征的颗粒物形态测量方法和装置
US12546694B2 (en) * 2019-11-20 2026-02-10 University Of Florida Research Foundation, Incorporated Method and apparatus for detecting acidity of airborne particles
JP7759328B2 (ja) 2020-01-24 2025-10-23 スリングショット バイオサイエンシーズ， インコーポレイテッド 細胞様較正粒子のための組成物および方法
CA3177834A1 (en) 2020-05-04 2021-11-11 Jeffrey Kim Compositions and methods for passive optical barcoding for multiplexed assays
JP2024539956A (ja) 2021-10-29 2024-10-31 スリングショット バイオサイエンシーズ， インコーポレイテッド フィーダー細胞としておよび合成抗原提示細胞としてのヒドロゲル粒子
CN119907921A (zh) 2022-05-05 2025-04-29 弹弓生物科学公司 用于血液学的作为红细胞模拟物的工程化颗粒和含有工程化颗粒的组合物
AU2023280490A1 (en) 2022-06-02 2024-12-05 Slingshot Biosciences, Inc. Apoptotic cell mimic
EP4608872A2 (en) 2022-10-26 2025-09-03 Slingshot Biosciences, Inc. Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation
WO2025049609A1 (en) 2023-08-29 2025-03-06 Slingshot Biosciences, Inc. Cd34 stem cell mimics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3497690A (en) * 1967-09-21 1970-02-24 Bausch & Lomb Method and apparatus for classifying biological cells by measuring the size and fluorescent response thereof
US3657537A (en) * 1970-04-03 1972-04-18 Bausch & Lomb Computerized slit-scan cyto-fluorometer for automated cell recognition
US3864571A (en) * 1971-02-10 1975-02-04 Wheeler International Inc Method and Apparatus for Automatically, Identifying and Counting Various Cells in Body Fluids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2196734A (en) * 1986-09-30 1988-05-05 Astromed Ltd Multiple assaying technique

Also Published As

Publication number Publication date
FR2236180B1 (https=) 1979-03-16
CH582882A5 (https=) 1976-12-15
AU6954774A (en) 1975-12-04
JPS5050093A (https=) 1975-05-06
NL7407776A (nl) 1975-01-06
FR2236180A1 (https=) 1975-01-31
US3872312A (en) 1975-03-18
AU476320B2 (en) 1976-09-16
DE2431203A1 (de) 1975-01-23
CA1002343A (en) 1976-12-28

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee