GB1443923A - Sustained release compositions - Google Patents

Sustained release compositions

Info

Publication number
GB1443923A
GB1443923A GB2041272A GB2041272A GB1443923A GB 1443923 A GB1443923 A GB 1443923A GB 2041272 A GB2041272 A GB 2041272A GB 2041272 A GB2041272 A GB 2041272A GB 1443923 A GB1443923 A GB 1443923A
Authority
GB
United Kingdom
Prior art keywords
fatty acid
agents
active material
melting point
pharmaceutically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2041272A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB2041272A priority Critical patent/GB1443923A/en
Publication of GB1443923A publication Critical patent/GB1443923A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Abstract

1443923 Delayed and sustained release compositions M SHEPARD 16 July 1973 [2 May 1972] 20412/72 Heading A5B Delayed release pharmaceutictal compositions in dosage unit form comprises two or more portions of pharmaceutically active material, each of which is individually provided with a retardant coating comprising a different water-insoluble normally solid fatty acid, each of the fatty acids having a melting point above body temperature and each fatty acid having a different melting point to the other(s). The fatty acid may be a saturated fatty acid such as lauric, myristic, stearic, behenic, lignoceric, palmitic or aracadic acid. The composition may also contain a portion of pharmaceutically active material having a coating of fatty acid having a melting point below body temperature i.e. capric acid. The composition may be in the form of granules which may be contained in a sachet or gelatine capsule, or compressed together with a tablet lubricant. The pharmaceutically active material may be selected from herbs, antihistamines, antibiotics, cardiovascular agents, central nervous system depressants, central nervous system stimulants, enzymes, gastrointestinal agents, haematological agents, immunological agents, hormones, renal acting and oedema reducing agents, nutrients and/or skeletal muscle relaxants.
GB2041272A 1972-05-02 1972-05-02 Sustained release compositions Expired GB1443923A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2041272A GB1443923A (en) 1972-05-02 1972-05-02 Sustained release compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2041272A GB1443923A (en) 1972-05-02 1972-05-02 Sustained release compositions

Publications (1)

Publication Number Publication Date
GB1443923A true GB1443923A (en) 1976-07-28

Family

ID=10145532

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2041272A Expired GB1443923A (en) 1972-05-02 1972-05-02 Sustained release compositions

Country Status (1)

Country Link
GB (1) GB1443923A (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2361915A1 (en) * 1976-08-20 1978-03-17 Ciba Geigy Ag LONG-TERM PHARMACEUTICAL DOSAGE FORMS
FR2405066A1 (en) * 1977-05-25 1979-05-04 Commw Scient Ind Res Org RELEASE COMPOSITIONS FOR THE ADMINISTRATION OF THERAPEUTIC AGENTS TO RUMINANTS
DE2950463A1 (en) * 1978-12-15 1980-06-26 Lehner Ag BALINE ACID CONTAINING PHARMACEUTICAL PREPARATION WITH EXTENDED EFFECT
FR2477015A1 (en) * 1980-03-03 1981-09-04 Fabre Sa Pierre PHARMACEUTICAL COMPOSITION BASED ON ALKALOID OF RYE DARK WITH REGULATORY ACTIVITY ON VASCULAR TONUS
EP0040439A2 (en) * 1980-05-21 1981-11-25 Shionogi & Co., Ltd. Sustained-release granular preparations
EP0049143A2 (en) * 1980-09-30 1982-04-07 Takeda Chemical Industries, Ltd. Granules of sodium ascorbate and the production thereof
US4609542A (en) * 1978-12-22 1986-09-02 Elan Corporation, P.L.C. New pharmaceutical forms for administration of medicaments by oral route, with programmed release
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
WO1998035655A2 (en) * 1997-02-14 1998-08-20 Gödecke Aktiengesellschaft Method for separating active substances in solid pharmaceutical preparations
WO2006072424A1 (en) * 2005-01-03 2006-07-13 Nextpharma Gmbh PHARMACEUTICAL COMPOSITION FOR CONTROLLED RELEASE OF β-LACTAM ANTIBIOTICS IN COMBINATION WITH β-LACTAMASE INHIBITORS
NL2022082B1 (en) * 2018-11-28 2020-06-25 Univ Free State Transport vessels for facilitating trans-membrane transport

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2361915A1 (en) * 1976-08-20 1978-03-17 Ciba Geigy Ag LONG-TERM PHARMACEUTICAL DOSAGE FORMS
FR2405066A1 (en) * 1977-05-25 1979-05-04 Commw Scient Ind Res Org RELEASE COMPOSITIONS FOR THE ADMINISTRATION OF THERAPEUTIC AGENTS TO RUMINANTS
DE2950463A1 (en) * 1978-12-15 1980-06-26 Lehner Ag BALINE ACID CONTAINING PHARMACEUTICAL PREPARATION WITH EXTENDED EFFECT
US4609542A (en) * 1978-12-22 1986-09-02 Elan Corporation, P.L.C. New pharmaceutical forms for administration of medicaments by oral route, with programmed release
US4726951A (en) * 1978-12-22 1988-02-23 Elan Corporation P.L.C. New pharmaceutical forms for administration of medicaments by oral route, with programmed release
FR2477015A1 (en) * 1980-03-03 1981-09-04 Fabre Sa Pierre PHARMACEUTICAL COMPOSITION BASED ON ALKALOID OF RYE DARK WITH REGULATORY ACTIVITY ON VASCULAR TONUS
EP0036350A1 (en) * 1980-03-03 1981-09-23 Pierre Fabre Medicament Pharmaceutical composition having a regulatory effect on vascular tone
US4892738A (en) * 1980-05-21 1990-01-09 Shionogi & Co., Ltd. Sustained-release granular pharmaceutical preparations
EP0040439A3 (en) * 1980-05-21 1982-09-01 Shionogi & Co., Ltd. Sustained-release granular preparations
EP0040439A2 (en) * 1980-05-21 1981-11-25 Shionogi & Co., Ltd. Sustained-release granular preparations
EP0049143A3 (en) * 1980-09-30 1982-12-29 Takeda Chemical Industries, Ltd. Granules of sodium ascorbate and the production thereof
EP0049143A2 (en) * 1980-09-30 1982-04-07 Takeda Chemical Industries, Ltd. Granules of sodium ascorbate and the production thereof
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
WO1998035655A2 (en) * 1997-02-14 1998-08-20 Gödecke Aktiengesellschaft Method for separating active substances in solid pharmaceutical preparations
WO1998035655A3 (en) * 1997-02-14 1998-11-26 Goedecke Ag Method for separating active substances in solid pharmaceutical preparations
WO2006072424A1 (en) * 2005-01-03 2006-07-13 Nextpharma Gmbh PHARMACEUTICAL COMPOSITION FOR CONTROLLED RELEASE OF β-LACTAM ANTIBIOTICS IN COMBINATION WITH β-LACTAMASE INHIBITORS
NL2022082B1 (en) * 2018-11-28 2020-06-25 Univ Free State Transport vessels for facilitating trans-membrane transport

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee