GB1439625A - Compositions for reducing blood cholesterol - Google Patents
Compositions for reducing blood cholesterolInfo
- Publication number
- GB1439625A GB1439625A GB4656473A GB4656473A GB1439625A GB 1439625 A GB1439625 A GB 1439625A GB 4656473 A GB4656473 A GB 4656473A GB 4656473 A GB4656473 A GB 4656473A GB 1439625 A GB1439625 A GB 1439625A
- Authority
- GB
- United Kingdom
- Prior art keywords
- represents hydrogen
- hydroxy
- compositions
- mixture
- blood cholesterol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 4
- 239000008280 blood Substances 0.000 title abstract 2
- 210000004369 blood Anatomy 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- KNHUKKLJHYUCFP-UHFFFAOYSA-N clofibrate Chemical compound CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 KNHUKKLJHYUCFP-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 101100188555 Arabidopsis thaliana OCT6 gene Proteins 0.000 abstract 1
- 239000004593 Epoxy Substances 0.000 abstract 1
- DWCSNWXARWMZTG-UHFFFAOYSA-N Trigonegenin A Natural products CC1C(C2(CCC3C4(C)CCC(O)C=C4CCC3C2C2)C)C2OC11CCC(C)CO1 DWCSNWXARWMZTG-UHFFFAOYSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 229960001214 clofibrate Drugs 0.000 abstract 1
- WQLVFSAGQJTQCK-VKROHFNGSA-N diosgenin Chemical compound O([C@@H]1[C@@H]([C@]2(CC[C@@H]3[C@@]4(C)CC[C@H](O)CC4=CC[C@H]3[C@@H]2C1)C)[C@@H]1C)[C@]11CC[C@@H](C)CO1 WQLVFSAGQJTQCK-VKROHFNGSA-N 0.000 abstract 1
- WQLVFSAGQJTQCK-UHFFFAOYSA-N diosgenin Natural products CC1C(C2(CCC3C4(C)CCC(O)CC4=CCC3C2C2)C)C2OC11CCC(C)CO1 WQLVFSAGQJTQCK-UHFFFAOYSA-N 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 150000003626 triacylglycerols Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA153,515A CA985172A (en) | 1972-10-06 | 1972-10-06 | Compositions and methods for reducing blood cholesterol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1439625A true GB1439625A (en) | 1976-06-16 |
Family
ID=4094630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4656473A Expired GB1439625A (en) | 1972-10-06 | 1973-10-05 | Compositions for reducing blood cholesterol |
Country Status (16)
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3838716A1 (de) * | 1988-11-15 | 1990-05-17 | Kanoldt Arzneimittel Gmbh | Arzneimittelzubereitung aus esterderivaten des hecogenins und dessen verwendung zur behandlung von benigner prostatahyperplasie |
| US6929807B1 (en) * | 1996-08-09 | 2005-08-16 | Mannatech, Inc. | Compositions of plant carbohydrates as dietary supplements |
| GB9923076D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| US20030118673A1 (en) * | 1998-03-26 | 2003-06-26 | Zongqin Xia | Smilagenin and anzurogenin-D for the treatment of alzheimer's disease |
| CN1198622C (zh) * | 1998-03-26 | 2005-04-27 | 植物药物公共有限公司 | 用于治疗阿尔茨海默病的甾类皂苷及其衍生物 |
| GB2347676A (en) * | 1999-03-08 | 2000-09-13 | Phytopharm Plc | Screening method |
| GB9923078D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| GB9923077D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| GB0000228D0 (en) * | 2000-01-06 | 2000-03-01 | Phytopharm Plc | Fluoro substituted sapogenins and their use |
| GB0107822D0 (en) * | 2001-03-28 | 2001-05-23 | Phytopharm Plc | Sapogenin derivatives their synthesis and use methods based upon their use |
| WO2003022287A1 (fr) * | 2001-08-24 | 2003-03-20 | Jilin Tianyao Science And Technology Co. Ltd. | UTILISATION DE 3β-HYDROXY-5-SPIROSTENE POUR PREVENIR OU TRAITER DES MALADIES OU DES ETATS CARDIO-VASCULAIRES, INHIBER DES TUMEURS ET REDUIRE LES LIPIDES SANGUINS |
| US20050130948A1 (en) * | 2002-03-27 | 2005-06-16 | Daryl Rees | Therapeutic methods and uses of sapogenins and their derivatives |
| CN102727501A (zh) * | 2002-03-27 | 2012-10-17 | 菲特法姆股份有限公司 | 皂角苷配基及其衍生物的用途 |
| AU2003231427A1 (en) * | 2002-04-15 | 2003-10-27 | Chengdu Di'ao Pharmaceutical Group Co., Ltd. | Compounds and preparation methods of carboxylate and monoester succinate derivative of diosgenin |
| GB0409567D0 (en) | 2004-04-28 | 2004-06-02 | Phytopharm Plc | Chemical compounds |
| US20090209489A1 (en) * | 2008-02-19 | 2009-08-20 | Roger Wayne Brown | Compositions for the treatment of diabetis, system PH disorders, high blood pressure, and a cancer marker system |
| US20090209486A1 (en) * | 2008-02-19 | 2009-08-20 | Roger Wayne Brown | Compositions of carbohydrates as dietary supplements |
| US20090209488A1 (en) * | 2008-02-19 | 2009-08-20 | Roger Wayne Brown | Compositions for the treatment of exercise induced asthma |
| US20090208588A1 (en) * | 2008-02-19 | 2009-08-20 | Roger Wayne Brown | GERD carbohydrate compositions |
| WO2012010896A1 (en) | 2010-07-20 | 2012-01-26 | Phytopharm Plc | Treatment of l-dopa, dopamine agonist and/or dopamine enhancer induced disorders |
| FR3133158A1 (fr) | 2022-03-04 | 2023-09-08 | Psa Automobiles Sa | Procédé de gestion énergetique d’une prise d’alimentation d’accessoire dans un véhicule automobile à l’arrêt |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE630211A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1962-03-28 |
-
1972
- 1972-10-06 CA CA153,515A patent/CA985172A/en not_active Expired
-
1973
- 1973-09-11 ZA ZA00737246A patent/ZA737246B/xx unknown
- 1973-09-17 US US398130A patent/US3890438A/en not_active Expired - Lifetime
- 1973-09-24 IE IE1698/73A patent/IE38274B1/xx unknown
- 1973-09-25 DE DE19732348176 patent/DE2348176A1/de active Pending
- 1973-10-01 IN IN2210/CAL/73A patent/IN138921B/en unknown
- 1973-10-02 NL NL7313519A patent/NL7313519A/xx not_active Application Discontinuation
- 1973-10-03 BE BE136318A patent/BE805634A/xx unknown
- 1973-10-04 HU HUAE394A patent/HU169814B/hu unknown
- 1973-10-05 FR FR7335748A patent/FR2201893B1/fr not_active Expired
- 1973-10-05 CS CS736877A patent/CS197387B1/cs unknown
- 1973-10-05 GB GB4656473A patent/GB1439625A/en not_active Expired
- 1973-10-05 ES ES419355A patent/ES419355A1/es not_active Expired
- 1973-10-05 SE SE7313618A patent/SE403886B/xx unknown
- 1973-10-05 DD DD173898A patent/DD106948A5/xx unknown
- 1973-10-08 AU AU61108/73A patent/AU477269B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE805634A (fr) | 1974-04-03 |
| CA985172A (en) | 1976-03-09 |
| SE403886B (sv) | 1978-09-11 |
| IE38274L (en) | 1974-04-06 |
| FR2201893A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-05-03 |
| HU169814B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-02-28 |
| ES419355A1 (es) | 1976-03-01 |
| DD106948A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-07-12 |
| FR2201893B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-09-09 |
| DE2348176A1 (de) | 1974-04-11 |
| CS197387B1 (en) | 1980-05-30 |
| NL7313519A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-04-09 |
| AU477269B2 (en) | 1976-10-21 |
| IN138921B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-04-17 |
| US3890438A (en) | 1975-06-17 |
| ZA737246B (en) | 1975-04-30 |
| IE38274B1 (en) | 1978-02-01 |
| AU6110873A (en) | 1975-04-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |