GB1432834A - Detecting malignant cells - Google Patents
Detecting malignant cellsInfo
- Publication number
- GB1432834A GB1432834A GB1991173A GB1991173A GB1432834A GB 1432834 A GB1432834 A GB 1432834A GB 1991173 A GB1991173 A GB 1991173A GB 1991173 A GB1991173 A GB 1991173A GB 1432834 A GB1432834 A GB 1432834A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cells
- gallium
- fluorescence
- hydroxyquinoline
- light
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000003211 malignant effect Effects 0.000 title abstract 4
- GYHNNYVSQQEPJS-UHFFFAOYSA-N Gallium Chemical compound [Ga] GYHNNYVSQQEPJS-UHFFFAOYSA-N 0.000 abstract 7
- 229910052733 gallium Inorganic materials 0.000 abstract 7
- 230000002285 radioactive effect Effects 0.000 abstract 4
- 239000005725 8-Hydroxyquinoline Substances 0.000 abstract 3
- 150000002259 gallium compounds Chemical class 0.000 abstract 3
- 229960003540 oxyquinoline Drugs 0.000 abstract 3
- MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 abstract 3
- LGDFHDKSYGVKDC-UHFFFAOYSA-N 8-hydroxyquinoline-5-sulfonic acid Chemical compound C1=CN=C2C(O)=CC=C(S(O)(=O)=O)C2=C1 LGDFHDKSYGVKDC-UHFFFAOYSA-N 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000005284 excitation Effects 0.000 abstract 1
- 238000005286 illumination Methods 0.000 abstract 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 abstract 1
- 229910052753 mercury Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Physiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00247740A US3857033A (en) | 1972-04-26 | 1972-04-26 | Detecting malignant cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1432834A true GB1432834A (en) | 1976-04-22 |
Family
ID=22936175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1991173A Expired GB1432834A (en) | 1972-04-26 | 1973-04-26 | Detecting malignant cells |
Country Status (4)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL43224A (en) * | 1973-09-14 | 1979-07-25 | Yeda Res & Dev | Fluorescence polarization measurements |
| US4070576A (en) * | 1976-02-02 | 1978-01-24 | American Science & Engineering, Inc. | Detecting malignant cells |
| US4112301A (en) * | 1976-06-03 | 1978-09-05 | American Science And Engineering, Inc. | Moving particles suspended in a carrier fluid through a flow channel having an input end under gas pressure |
| US4044253A (en) * | 1976-06-04 | 1977-08-23 | The United States Of America As Represented By The Secretary Of The Air Force | Non-destructive inspection of composite and adhesively bonded structures |
| US6026174A (en) * | 1992-10-14 | 2000-02-15 | Accumed International, Inc. | System and method for automatically detecting malignant cells and cells having malignancy-associated changes |
| US6051393A (en) * | 1994-03-29 | 2000-04-18 | Jones; Sonja K. | Method of detecting malignant and pre-malignant conditions of the cervix, and test kits therefor |
| US20140242600A1 (en) * | 2011-06-08 | 2014-08-28 | The Board Of Trustees Of The Leland Stanford Junior University | Imaging the heterogeneous uptake of radiolabeled molecules in single living cells |
| US10175219B2 (en) | 2014-07-28 | 2019-01-08 | The Board Of Trustees Of The Leland Stanford Junior University | Method to sort cells on the basis of radionuclide uptake |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3497690A (en) * | 1967-09-21 | 1970-02-24 | Bausch & Lomb | Method and apparatus for classifying biological cells by measuring the size and fluorescent response thereof |
| US3673410A (en) * | 1969-06-25 | 1972-06-27 | John H Waite | Method of examination of cell samples using a radioactively tagged dye |
| US3678148A (en) * | 1969-06-26 | 1972-07-18 | Information Utilization Corp | Radioactive slide specimen analysis of and method of preparation |
| US3586859A (en) * | 1970-02-16 | 1971-06-22 | Irwin J Katz | Fluorescent cell viability counter |
-
1972
- 1972-04-26 US US00247740A patent/US3857033A/en not_active Expired - Lifetime
-
1973
- 1973-04-26 DE DE2321050A patent/DE2321050A1/de active Pending
- 1973-04-26 GB GB1991173A patent/GB1432834A/en not_active Expired
- 1973-04-26 FR FR7315202A patent/FR2182154B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2182154B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-08-19 |
| FR2182154A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-12-07 |
| DE2321050A1 (de) | 1973-11-08 |
| US3857033A (en) | 1974-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |