GB1416271A - Psychopharmacologically active peptides - Google Patents
Psychopharmacologically active peptidesInfo
- Publication number
- GB1416271A GB1416271A GB621973A GB621973A GB1416271A GB 1416271 A GB1416271 A GB 1416271A GB 621973 A GB621973 A GB 621973A GB 621973 A GB621973 A GB 621973A GB 1416271 A GB1416271 A GB 1416271A
- Authority
- GB
- United Kingdom
- Prior art keywords
- butoxycarbonyl
- methionine
- tert
- nitroarginyl
- tertbutoxycarbonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- -1 succinimido ester Chemical class 0.000 abstract 3
- KKJLMWHWMXENCQ-AWEZNQCLSA-N (2S)-5-(diaminomethylideneamino)-N-[2-(1H-indol-3-yl)ethyl]-2-nitramidopentanamide Chemical compound [N+](=O)([O-])N[C@@H](CCCNC(N)=N)C(=O)NCCC1=CNC2=CC=CC=C12 KKJLMWHWMXENCQ-AWEZNQCLSA-N 0.000 abstract 1
- IMUSLIHRIYOHEV-ZETCQYMHSA-N (2s)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoic acid Chemical compound CSCC[C@@H](C(O)=O)NC(=O)OC(C)(C)C IMUSLIHRIYOHEV-ZETCQYMHSA-N 0.000 abstract 1
- FVSDTYGQCVACMH-ISJKBYAMSA-N (2s)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfinylbutanoic acid Chemical compound CS(=O)CC[C@@H](C(O)=O)NC(=O)OC(C)(C)C FVSDTYGQCVACMH-ISJKBYAMSA-N 0.000 abstract 1
- SZXBQTSZISFIAO-ZETCQYMHSA-N (2s)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid Chemical compound CC(C)[C@@H](C(O)=O)NC(=O)OC(C)(C)C SZXBQTSZISFIAO-ZETCQYMHSA-N 0.000 abstract 1
- DCUQRNAKJBVFDN-ZETCQYMHSA-N (2s)-5-(diaminomethylideneazaniumyl)-2-[(2-methylpropan-2-yl)oxycarbonyl-nitroamino]pentanoate Chemical compound CC(C)(C)OC(=O)N([N+]([O-])=O)[C@H](C(O)=O)CCCNC(N)=N DCUQRNAKJBVFDN-ZETCQYMHSA-N 0.000 abstract 1
- QVHJQCGUWFKTSE-UHFFFAOYSA-N 2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid Chemical compound OC(=O)C(C)NC(=O)OC(C)(C)C QVHJQCGUWFKTSE-UHFFFAOYSA-N 0.000 abstract 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 abstract 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- 229930195722 L-methionine Natural products 0.000 abstract 1
- QEFRNWWLZKMPFJ-YGVKFDHGSA-N L-methionine S-oxide Chemical compound CS(=O)CC[C@H](N)C(O)=O QEFRNWWLZKMPFJ-YGVKFDHGSA-N 0.000 abstract 1
- QEFRNWWLZKMPFJ-UHFFFAOYSA-N L-methionine sulphoxide Natural products CS(=O)CCC(N)C(O)=O QEFRNWWLZKMPFJ-UHFFFAOYSA-N 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000003862 amino acid derivatives Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229960004452 methionine Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- APJYDQYYACXCRM-UHFFFAOYSA-N tryptamine Chemical compound C1=CC=C2C(CCN)=CNC2=C1 APJYDQYYACXCRM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/695—Corticotropin [ACTH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7202278A NL7202278A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-02-22 | 1972-02-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1416271A true GB1416271A (en) | 1975-12-03 |
Family
ID=19815436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB621973A Expired GB1416271A (en) | 1972-02-22 | 1973-02-08 | Psychopharmacologically active peptides |
Country Status (12)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7607684A (nl) * | 1976-07-12 | 1978-01-16 | Akzo Nv | Werkwijze ter bereiding van nieuwe peptiden en peptide-derivaten en de toepassing hiervan. |
| US4623715A (en) * | 1984-10-22 | 1986-11-18 | Hoechst Aktiengeselleschaft | Novel peptides which are active on the central nervous system and have an action on the cholinergic system |
| AU583578B2 (en) * | 1984-12-14 | 1989-05-04 | Australian Commercial Research & Development Limited | Amino acid and peptide inhibitors of human leucocytic elastase |
| US5462927A (en) * | 1985-04-30 | 1995-10-31 | The Administrators Of The Tulane Educational Fund | Peptides aiding nerve regeneration |
| JP2525798B2 (ja) * | 1987-03-12 | 1996-08-21 | 第一製薬株式会社 | ペプチド誘導体 |
| WO1993000922A1 (en) * | 1991-07-01 | 1993-01-21 | The Administrators Of The Tulane Educational Fund | Peptides aiding nerve regeneration |
| WO2003006620A2 (en) * | 2001-07-11 | 2003-01-23 | Palatin Technologies, Inc. | Linear and cyclic melanocortin receptor-specific peptides |
| US7176279B2 (en) * | 2000-06-28 | 2007-02-13 | Palatin Technologies, Inc. | Cyclic peptide compositions and methods for treatment of sexual dysfunction |
| US6579968B1 (en) * | 1999-06-29 | 2003-06-17 | Palatin Technologies, Inc. | Compositions and methods for treatment of sexual dysfunction |
| ATE375792T1 (de) * | 2000-08-25 | 2007-11-15 | Res Corp Technologies Inc | Verwendung von antikonvulsiven aminosäure zur behandlung von migräne |
| US6974187B2 (en) * | 2004-01-28 | 2005-12-13 | Tachi-S Co., Ltd. | Vehicle seat structure |
| DK1751273T3 (da) * | 2004-04-08 | 2011-05-02 | Astellas Pharma Inc | Forbindelse WS727713 |
| AU2005231034B2 (en) * | 2004-04-08 | 2010-04-08 | Telsar Pharma Inc. | Compound WS727713 |
| DK2560486T3 (en) | 2010-04-21 | 2019-02-04 | Signature Therapeutics Inc | COMPOSITIONS COMPREHENSIVE ENZYM-TENDABLE AMPHETAMINE PRODRUGS AND ITS INHIBITORS |
| US11590209B2 (en) | 2020-01-21 | 2023-02-28 | Palatin Technologies, Inc. | Use of bremelanotide in patients with controlled hypertension |
| AU2021382158B2 (en) * | 2020-11-18 | 2024-08-01 | Mind Medicine, Inc. | Mdma prodrugs to assist psychotherapy |
| MX2024003466A (es) | 2021-09-29 | 2024-06-04 | Ensysce Biosciences Inc | Profarmacos de metadona escindibles por enzimas y metodos de uso de los mismos. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1302396A (fr) * | 1961-03-10 | 1962-08-31 | Ciba Geigy | Procédés de préparation de nouveaux heptapeptides de formule l-alpha-[mercaptoalcoyl (inférieur)]-alpha-amino-acétyl-l-glutaminyl-l-histidyl-l-phényl alanyl-l-alpha-[amino-alcoyl (inférieur)]-alpha-amino-acétyl-l-tryptophyl glycine |
| NL278010A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1961-05-04 | 1900-01-01 | ||
| NL6509727A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1965-07-28 | 1967-01-30 | ||
| GB1230472A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1967-07-10 | 1971-05-05 |
-
0
- BE BE795788D patent/BE795788A/xx unknown
-
1972
- 1972-02-22 NL NL7202278A patent/NL7202278A/xx unknown
-
1973
- 1973-02-06 ZA ZA730839A patent/ZA73839B/xx unknown
- 1973-02-08 GB GB621973A patent/GB1416271A/en not_active Expired
- 1973-02-08 AU AU51979/73A patent/AU471298B2/en not_active Expired
- 1973-02-12 US US00331945A patent/US3853836A/en not_active Expired - Lifetime
- 1973-02-20 DE DE19732308362 patent/DE2308362A1/de active Pending
- 1973-02-20 HU HUAO351A patent/HU168890B/hu unknown
- 1973-02-21 JP JP48021120A patent/JPS4896586A/ja active Pending
- 1973-02-21 CH CH245873A patent/CH585192A5/xx not_active IP Right Cessation
- 1973-02-21 CA CA164,274A patent/CA1030953A/en not_active Expired
- 1973-02-22 FR FR7306338A patent/FR2181759B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU471298B2 (en) | 1976-04-15 |
| DE2308362A1 (de) | 1973-09-06 |
| ZA73839B (en) | 1973-11-28 |
| BE795788A (nl) | 1973-08-22 |
| JPS4896586A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-12-10 |
| AU5197973A (en) | 1974-08-08 |
| CH585192A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-02-28 |
| HU168890B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-08-28 |
| CA1030953A (en) | 1978-05-09 |
| FR2181759B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-09-03 |
| NL7202278A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-08-24 |
| FR2181759A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-12-07 |
| US3853836A (en) | 1974-12-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |