GB1397387A - Preparation of 2-alkylaminoalkyl 6-methyl-7-nitro- 1,2,3,4-tetrahydroquinolines - Google Patents
Preparation of 2-alkylaminoalkyl 6-methyl-7-nitro- 1,2,3,4-tetrahydroquinolinesInfo
- Publication number
- GB1397387A GB1397387A GB306873A GB306873A GB1397387A GB 1397387 A GB1397387 A GB 1397387A GB 306873 A GB306873 A GB 306873A GB 306873 A GB306873 A GB 306873A GB 1397387 A GB1397387 A GB 1397387A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- nitro
- tetrahydroquinolines
- compounds
- alkylaminoalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000006396 nitration reaction Methods 0.000 abstract 2
- GLIWLNLROCTMCK-UHFFFAOYSA-N (6-methyl-7-nitro-2-propan-2-yl-3,4-dihydro-2H-quinolin-1-yl)methanamine Chemical compound C(C)(C)C1N(C2=CC(=C(C=C2CC1)C)[N+](=O)[O-])CN GLIWLNLROCTMCK-UHFFFAOYSA-N 0.000 abstract 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000020176 deacylation Effects 0.000 abstract 1
- 238000005947 deacylation reaction Methods 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000002906 microbiologic effect Effects 0.000 abstract 1
- ZODDGFAZWTZOSI-UHFFFAOYSA-N nitric acid;sulfuric acid Chemical compound O[N+]([O-])=O.OS(O)(=O)=O ZODDGFAZWTZOSI-UHFFFAOYSA-N 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- HXJUTPCZVOIRIF-UHFFFAOYSA-N sulfolane Chemical compound O=S1(=O)CCCC1 HXJUTPCZVOIRIF-UHFFFAOYSA-N 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/28—Alcohols; Ethers thereof with halogen atoms or nitro radicals in positions 5, 6 or 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB306873A GB1397387A (en) | 1973-01-20 | 1973-01-20 | Preparation of 2-alkylaminoalkyl 6-methyl-7-nitro- 1,2,3,4-tetrahydroquinolines |
| JP13743673A JPS5429510B2 (enrdf_load_stackoverflow) | 1973-01-20 | 1973-12-11 | |
| NL7400700A NL159378B (nl) | 1973-01-20 | 1974-01-18 | Werkwijze voor het bereiden van 2-aminoalkyl-6-methyl-7-nitro-1,2,3,4-tetrahydrochinolinen, werkwijze voor het bereiden van een farmaceutisch preparaat, alsmede gevormd farmaceutisch preparaat. |
| CH71574A CH590843A5 (enrdf_load_stackoverflow) | 1973-01-20 | 1974-01-18 | |
| ES422465A ES422465A1 (es) | 1973-01-20 | 1974-01-19 | Procedimiento para preparar 2-amino-alquil-6-metil-7-nitro-1, 2, 3, 4 tetrahidroquinolinas. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB306873A GB1397387A (en) | 1973-01-20 | 1973-01-20 | Preparation of 2-alkylaminoalkyl 6-methyl-7-nitro- 1,2,3,4-tetrahydroquinolines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1397387A true GB1397387A (en) | 1975-06-11 |
Family
ID=9751399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB306873A Expired GB1397387A (en) | 1973-01-20 | 1973-01-20 | Preparation of 2-alkylaminoalkyl 6-methyl-7-nitro- 1,2,3,4-tetrahydroquinolines |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5429510B2 (enrdf_load_stackoverflow) |
| CH (1) | CH590843A5 (enrdf_load_stackoverflow) |
| ES (1) | ES422465A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1397387A (enrdf_load_stackoverflow) |
| NL (1) | NL159378B (enrdf_load_stackoverflow) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5056535A (enrdf_load_stackoverflow) * | 1973-09-21 | 1975-05-17 | ||
| JPS50160739A (enrdf_load_stackoverflow) * | 1974-06-18 | 1975-12-26 | ||
| JPS51138828A (en) * | 1975-05-26 | 1976-11-30 | Fujikura Ltd | Method of manufacturing separator for battery |
| FR2393815A1 (fr) * | 1977-06-07 | 1979-01-05 | Solvay | Procede pour la polymerisation en suspension aqueuse du chlorure de vinyle |
| DE19935692A1 (de) * | 1999-07-29 | 2001-02-01 | Merck Patent Gmbh | Nitrierung in einem statischen Mikromischer |
-
1973
- 1973-01-20 GB GB306873A patent/GB1397387A/en not_active Expired
- 1973-12-11 JP JP13743673A patent/JPS5429510B2/ja not_active Expired
-
1974
- 1974-01-18 NL NL7400700A patent/NL159378B/xx not_active IP Right Cessation
- 1974-01-18 CH CH71574A patent/CH590843A5/xx not_active IP Right Cessation
- 1974-01-19 ES ES422465A patent/ES422465A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH590843A5 (enrdf_load_stackoverflow) | 1977-08-31 |
| NL159378B (nl) | 1979-02-15 |
| JPS5429510B2 (enrdf_load_stackoverflow) | 1979-09-25 |
| NL7400700A (enrdf_load_stackoverflow) | 1974-07-23 |
| ES422465A1 (es) | 1976-05-01 |
| JPS5012092A (enrdf_load_stackoverflow) | 1975-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19940115 |