GB1358893A - Triazole derivatives their preparation and compositions containing them - Google Patents
Triazole derivatives their preparation and compositions containing themInfo
- Publication number
- GB1358893A GB1358893A GB4375471A GB4375471A GB1358893A GB 1358893 A GB1358893 A GB 1358893A GB 4375471 A GB4375471 A GB 4375471A GB 4375471 A GB4375471 A GB 4375471A GB 1358893 A GB1358893 A GB 1358893A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- alkyl
- hydrogen atom
- optionally
- pyridyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title 1
- 229940042055 systemic antimycotics triazole derivative Drugs 0.000 title 1
- 150000001204 N-oxides Chemical class 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000004076 pyridyl group Chemical group 0.000 abstract 3
- 150000000178 1,2,4-triazoles Chemical class 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- NSPMIYGKQJPBQR-UHFFFAOYSA-N 4H-1,2,4-triazole Chemical compound C=1N=CNN=1 NSPMIYGKQJPBQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000005115 alkyl carbamoyl group Chemical group 0.000 abstract 1
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 125000006383 alkylpyridyl group Chemical group 0.000 abstract 1
- 230000002961 anti-hyperuricemic effect Effects 0.000 abstract 1
- 230000002959 anti-hypotensive effect Effects 0.000 abstract 1
- 229960002708 antigout preparations Drugs 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 230000002252 carbamoylating effect Effects 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000005344 pyridylmethyl group Chemical group [H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- -1 sulphamoyl Chemical group 0.000 abstract 1
- 150000003852 triazoles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Slide Fasteners (AREA)
- Details Of Garments (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7578570A | 1970-09-25 | 1970-09-25 | |
| DE2216829A DE2216829A1 (de) | 1970-09-25 | 1972-04-07 | Reissverschluss |
| US26968472A | 1972-07-07 | 1972-07-07 | |
| US05/529,151 US4011218A (en) | 1970-09-25 | 1974-12-03 | 1,2,4-triazoles |
| US54356375A | 1975-01-23 | 1975-01-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1358893A true GB1358893A (en) | 1974-07-03 |
Family
ID=27510246
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4375471A Expired GB1358893A (en) | 1970-09-25 | 1971-09-20 | Triazole derivatives their preparation and compositions containing them |
| GB1623073A Expired GB1415563A (en) | 1970-09-25 | 1973-04-05 | Sliding clasp fasteners |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1623073A Expired GB1415563A (en) | 1970-09-25 | 1973-04-05 | Sliding clasp fasteners |
Country Status (9)
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5104884A (en) * | 1985-05-07 | 1992-04-14 | Alkaloida Vegyeszeti Gyar | Triazolyl quinoline derivatives |
| US6191136B1 (en) | 1997-11-07 | 2001-02-20 | Johns Hopkins University | Methods for treatment of disorders of cardiac contractility |
| CN102186827A (zh) * | 2008-09-04 | 2011-09-14 | 亚德生化公司 | 调节尿酸含量的化合物、组合物及其使用方法 |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7112373A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1970-09-25 | 1972-03-28 | ||
| US3882134A (en) * | 1973-05-21 | 1975-05-06 | Merck & Co Inc | 1-Substituted-3,5-dipyridyl-1,2,4-triazoles |
| US4104393A (en) * | 1976-04-02 | 1978-08-01 | Merck & Co., Inc. | 1,3,5-Trisubstituted-1,2,4-triazole compounds |
| US4137733A (en) * | 1976-05-20 | 1979-02-06 | Optilon W. Erich Heilmann Gmbh | Slide-fastener-stringer half with knitted-in coupling elements and method of making same |
| DE2622529B2 (de) * | 1976-05-20 | 1979-08-02 | Optilon W. Erich Heilmann Gmbh, Cham (Schweiz) | Reißverschluß |
| DE2745496A1 (de) * | 1977-10-10 | 1979-05-17 | Bayer Ag | Neue 1-n-substituierte 1.4-dihydropyridazine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| US4256887A (en) * | 1978-04-06 | 1981-03-17 | Merck & Co., Inc. | 1,2,4-Triazoles and a method for their preparation |
| AT376423B (de) * | 1978-04-26 | 1984-11-26 | Glaxo Group Ltd | Verfahren zur herstellung von neuen 1,2,4triazolderivaten |
| US4276297A (en) * | 1979-06-18 | 1981-06-30 | Pfizer Inc. | Pyridylaminotriazole therapeutic agents |
| US4400516A (en) * | 1979-10-15 | 1983-08-23 | The Dow Chemical Co. | Heterocyclic substituted triazole-3-ol compounds |
| DE3026487C1 (de) * | 1980-07-12 | 1984-08-02 | Optilon W. Erich Heilmann GmbH, Cham | Reissverschluss mit gewirkten Tragbaendern und darin eingewirkten Verschlussgliederreihen |
| DE3026448A1 (de) * | 1980-07-12 | 1982-02-04 | Bayer Ag, 5090 Leverkusen | Antitumoral wirkende mittel |
| US4338453A (en) * | 1980-09-17 | 1982-07-06 | The Upjohn Company | Aminoalkyl-1,2,4-triazoles |
| DE3439450A1 (de) * | 1984-10-27 | 1986-05-07 | Boehringer Ingelheim KG, 6507 Ingelheim | 1,2,4-triazolo-carbamate und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel |
| DE3514450A1 (de) * | 1985-04-22 | 1986-10-23 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von imidaten sowie neue arylsubstituierte imidate |
| DE3634162A1 (de) * | 1986-10-07 | 1988-04-21 | Ries Gmbh Bekleidungsverschlus | Reissverschluss und verfahren zu dessen herstellung |
| EP0385100A1 (de) * | 1989-02-25 | 1990-09-05 | Opti Patent-, Forschungs- und Fabrikations-AG | Reissverschluss mit zwei schraubenwendelförmigen Verschlussgliederreihen aus Kunststoffmonofilament |
| DE3905933A1 (de) * | 1989-02-25 | 1990-09-06 | Opti Patent Forschung Fab | Reissverschluss mit zwei schraubenwendelfoermigen verschlussgliederreihen aus kunststoffmonofilament |
| DE3905934A1 (de) * | 1989-02-25 | 1990-09-06 | Opti Patent Forschung Fab | Reissverschluss mit zwei schraubenwendelfoermigen verschlussgliederreihen aus kunststoffmonofilament |
| SE465448B (sv) * | 1990-01-31 | 1991-09-16 | Eng Tex Ab | Foer arbetsklaeder avsett inlaegg, som skydd mot kedjesaag |
| JPH05262764A (ja) * | 1992-01-24 | 1993-10-12 | Morishita Roussel Kk | １−アリール−２−（１ｈ−１，２，４−トリアゾー ル−１−イル）エタノール誘導体 |
| JP3217846B2 (ja) * | 1992-03-04 | 2001-10-15 | クミアイ化学工業株式会社 | トリアゾール誘導体及び殺虫剤 |
| US5482951A (en) * | 1992-05-29 | 1996-01-09 | Kumiai Chemical Industry Co., Ltd. | Triazole derivatives as well as insecticide and acaricide |
| TW226993B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1992-05-29 | 1994-07-21 | Kumiai Chemical Industry Co | |
| TW324158U (en) * | 1994-06-23 | 1998-01-01 | Ykk Corp | Knit slide fastener |
| JP3398828B2 (ja) * | 1994-06-23 | 2003-04-21 | ワイケイケイ株式会社 | 編込みスライドファスナー |
| JP3407165B2 (ja) * | 1995-05-18 | 2003-05-19 | ワイケイケイ株式会社 | 編込みスライドファスナー |
| US5502986A (en) * | 1995-06-21 | 1996-04-02 | Ykk Corporation | Knit slide fastener |
| JP3587673B2 (ja) * | 1997-12-26 | 2004-11-10 | Ｙｋｋ株式会社 | 編込みスライドファスナー |
| US6544785B1 (en) * | 1998-09-14 | 2003-04-08 | Mount Sinai School Of Medicine Of New York University | Helper-free rescue of recombinant negative strand RNA viruses |
| US6413992B1 (en) * | 1998-10-23 | 2002-07-02 | Dow Agrosciences Llc | 3-(substituted pyridyl)-1,2,4-triazole compounds |
| US6413997B1 (en) | 1998-10-23 | 2002-07-02 | Dow Agrosciences Llc | 3-(substituted phenyl)-5-(substituted heterocyclyl)-1,2,4-triazole compounds |
| JP3552947B2 (ja) * | 1999-04-30 | 2004-08-11 | Ｙｋｋ株式会社 | 編込みスライドファスナー |
| CN1561340B (zh) * | 2002-01-28 | 2012-05-23 | 株式会社富士药品 | 1,2,4-三唑类化合物 |
| JP4450758B2 (ja) * | 2005-03-25 | 2010-04-14 | Ｙｋｋ株式会社 | 編込みスライドファスナー |
| KR101411806B1 (ko) | 2007-11-27 | 2014-06-24 | 아디아 바이오사이언스즈 인크. | 신규한 화합물 및 조성물과 사용 방법 |
| US8242154B2 (en) | 2008-09-04 | 2012-08-14 | Ardea Biosciences, Inc. | Compounds, compositions and methods of using same for modulating uric acid levels |
| AU2014208964B2 (en) | 2013-01-23 | 2016-09-01 | Astrazeneca Ab | Chemical compounds |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1092359A (fr) * | 1952-10-06 | 1955-04-20 | May & Baker Ltd | Nouveaux composés hétérocycliques et leur préparation |
| FR1238943A (fr) * | 1958-08-19 | 1960-08-19 | Basf Ag | Procédé pour la production de triazoles-1-2-4 disubstitués en 3-5 |
| US3236853A (en) * | 1962-07-19 | 1966-02-22 | Hoechst Ag | Triazolidines and process for preparing them |
| US3308131A (en) * | 1962-12-06 | 1967-03-07 | Du Pont | Tertiary carbamyl triazoles |
| US3435115A (en) * | 1964-12-15 | 1969-03-25 | Pfizer & Co C | Lipid regulation with 5-(pyridyl) tetrazole derivatives |
| US3515723A (en) * | 1967-11-14 | 1970-06-02 | Merck & Co Inc | 2 - (5 - amino - 1h - 1,2,4 - triazol - 3 - yl)- 3-aminopyrazines and processes for their preparation |
| GB1242048A (en) * | 1969-06-03 | 1971-08-11 | Lightning Fasteners Ltd | Sliding clasp fastener stringers |
| US3651666A (en) * | 1970-06-29 | 1972-03-28 | Lightning Fasteners Ltd | Sliding clasp fastener stringers |
| US3657904A (en) * | 1970-07-06 | 1972-04-25 | Lightning Fasteners Ltd | Sliding clasp fastener stringers |
| NL7112373A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1970-09-25 | 1972-03-28 | ||
| NL7112372A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1970-09-25 | 1972-03-28 | ||
| US3879404A (en) * | 1972-07-07 | 1975-04-22 | John J Baldwin | Certain 5-(pyridyl)-3(phenyl)-1,2,4-triazoles |
-
1971
- 1971-09-08 NL NL7112373A patent/NL7112373A/xx not_active Application Discontinuation
- 1971-09-14 CA CA122,845,A patent/CA950463A/en not_active Expired
- 1971-09-20 GB GB4375471A patent/GB1358893A/en not_active Expired
- 1971-09-24 DE DE19712147794 patent/DE2147794A1/de not_active Ceased
- 1971-09-24 FR FR7134442A patent/FR2107984B1/fr not_active Expired
- 1971-09-24 CH CH1392271A patent/CH562813A5/xx not_active IP Right Cessation
-
1972
- 1972-03-22 BE BE781055A patent/BE781055A/xx unknown
- 1972-04-07 DE DE2216829A patent/DE2216829A1/de active Pending
-
1973
- 1973-04-05 GB GB1623073A patent/GB1415563A/en not_active Expired
- 1973-04-06 AU AU54226/73A patent/AU475491B2/en not_active Expired
- 1973-04-06 FR FR7312464A patent/FR2179222B1/fr not_active Expired
- 1973-04-09 US US349005A patent/US3864945A/en not_active Expired - Lifetime
-
1974
- 1974-12-03 US US05/529,151 patent/US4011218A/en not_active Expired - Lifetime
-
1976
- 1976-09-13 US US05/722,968 patent/US4071518A/en not_active Expired - Lifetime
- 1976-11-09 US US05/740,290 patent/US4102889A/en not_active Expired - Lifetime
-
1978
- 1978-02-21 US US05/879,530 patent/US4156085A/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5104884A (en) * | 1985-05-07 | 1992-04-14 | Alkaloida Vegyeszeti Gyar | Triazolyl quinoline derivatives |
| US6191136B1 (en) | 1997-11-07 | 2001-02-20 | Johns Hopkins University | Methods for treatment of disorders of cardiac contractility |
| US6569862B1 (en) | 1997-11-07 | 2003-05-27 | Johns Hopkins University | Methods for treatment of disorders of cardiac contractility |
| CN102186827A (zh) * | 2008-09-04 | 2011-09-14 | 亚德生化公司 | 调节尿酸含量的化合物、组合物及其使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU475491B2 (en) | 1976-08-26 |
| CA950463A (en) | 1974-07-02 |
| CH562813A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-06-13 |
| AU3342771A (en) | 1973-03-22 |
| FR2179222A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-11-16 |
| FR2179222B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-11-12 |
| US4156085A (en) | 1979-05-22 |
| NL7112373A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-03-28 |
| GB1415563A (en) | 1975-11-26 |
| FR2107984A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-05-12 |
| US3864945A (en) | 1975-02-11 |
| AU5422673A (en) | 1974-10-10 |
| US4071518A (en) | 1978-01-31 |
| DE2147794A1 (de) | 1972-03-30 |
| BE781055A (fr) | 1972-09-22 |
| US4011218A (en) | 1977-03-08 |
| DE2216829A1 (de) | 1973-10-18 |
| FR2107984B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-08-01 |
| US4102889A (en) | 1978-07-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |