GB1282308A - New thiadiazolyl-ureas, their production and composition containing same - Google Patents
New thiadiazolyl-ureas, their production and composition containing sameInfo
- Publication number
- GB1282308A GB1282308A GB35803/69A GB3580369A GB1282308A GB 1282308 A GB1282308 A GB 1282308A GB 35803/69 A GB35803/69 A GB 35803/69A GB 3580369 A GB3580369 A GB 3580369A GB 1282308 A GB1282308 A GB 1282308A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbon atoms
- aliphatic
- ureas
- triazines
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000001931 aliphatic group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001735 carboxylic acids Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 230000002363 herbicidal effect Effects 0.000 abstract 2
- 239000004009 herbicide Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 2
- 229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 2
- -1 uracils Chemical class 0.000 abstract 2
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000007933 aliphatic carboxylic acids Chemical class 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001559 benzoic acids Chemical class 0.000 abstract 1
- 235000013877 carbamide Nutrition 0.000 abstract 1
- 229940112021 centrally acting muscle relaxants carbamic acid ester Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004891 diazines Chemical class 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229940042795 hydrazides for tuberculosis treatment Drugs 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical class OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 abstract 1
- ISYCTVJTNGTOOM-UHFFFAOYSA-N thiadiazole;urea Chemical class NC(N)=O.C1=CSN=N1 ISYCTVJTNGTOOM-UHFFFAOYSA-N 0.000 abstract 1
- 150000003560 thiocarbamic acids Chemical class 0.000 abstract 1
- 150000003852 triazoles Chemical class 0.000 abstract 1
- 150000003672 ureas Chemical class 0.000 abstract 1
- JOYRKODLDBILNP-UHFFFAOYSA-N urethane group Chemical group NC(=O)OCC JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/36—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1069168A CH498859A (de) | 1968-07-17 | 1968-07-17 | Verfahren zur Herstellung von Thiadiazolyl-harnstoffen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1282308A true GB1282308A (en) | 1972-07-19 |
Family
ID=4365813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB35803/69A Expired GB1282308A (en) | 1968-07-17 | 1969-07-16 | New thiadiazolyl-ureas, their production and composition containing same |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS5440610B1 (instruction) |
| AT (1) | AT291668B (instruction) |
| BE (1) | BE736171A (instruction) |
| BG (1) | BG16312A3 (instruction) |
| CH (2) | CH498859A (instruction) |
| CS (1) | CS157651B2 (instruction) |
| DE (1) | DE1936241A1 (instruction) |
| DK (1) | DK139357B (instruction) |
| ES (4) | ES369572A1 (instruction) |
| FR (1) | FR2013116A1 (instruction) |
| GB (1) | GB1282308A (instruction) |
| IL (1) | IL32632A (instruction) |
| NL (1) | NL6910940A (instruction) |
| PL (1) | PL80180B1 (instruction) |
| RO (1) | RO61084A (instruction) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007006814A1 (en) * | 2005-07-14 | 2007-01-18 | Novo Nordisk A/S | Urea glucokinase activators |
| US7582769B2 (en) | 2005-07-08 | 2009-09-01 | Novo Nordisk A/S | Dicycloalkyl urea glucokinase activators |
| US7598391B2 (en) | 2004-01-06 | 2009-10-06 | Novo Nordisk A/S | Heteroaryl-ureas and their use as glucokinase activators |
| US7897628B2 (en) | 2002-06-27 | 2011-03-01 | Novo Nordisk A/S | Aryl carbonyl derivatives as therapeutic agents |
| US7999114B2 (en) | 2005-07-08 | 2011-08-16 | Novo Nordisk A/S | Dicycloalkylcarbamoyl ureas as glucokinase activators |
| US8138185B2 (en) | 2007-01-09 | 2012-03-20 | Novo Nordisk A/S | Urea glucokinase activators |
| US8318778B2 (en) | 2007-01-11 | 2012-11-27 | Novo Nordisk A/S | Urea glucokinase activators |
| US11833136B2 (en) | 2018-06-12 | 2023-12-05 | Vtv Therapeutics Llc | Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs |
| US12391658B2 (en) | 2020-02-18 | 2025-08-19 | Vtv Therapeutics Llc | Sulfoxide and sulfone glucokinase activators and methods of use thereof |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH498859A (de) * | 1968-07-17 | 1970-11-15 | Agripat Sa | Verfahren zur Herstellung von Thiadiazolyl-harnstoffen |
| DE2059328C2 (de) * | 1970-11-24 | 1984-02-23 | Schering AG, 1000 Berlin und 4709 Bergkamen | 1,1,3-Trimethyl-3-(5-äthylsulfinyl-1,3,4-thiadiazol-2-YL)-harnstoff |
| DE2044442C2 (de) * | 1970-09-03 | 1983-11-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | 1,1,3-Trimethyl-3-(-5-Äthylsulfonyl-1,3,4-Thiadiazol-2-yl)-Harnstoff mit herbizider Wirkung |
| DE2719810A1 (de) | 1977-04-28 | 1978-11-02 | Schering Ag | 1,2,3-thiadiazolin-2-id-derivate, verfahren zur herstellung dieser verbindungen sowie diese enthaltende mittel mit wachstumsregulatorischer wirkung fuer pflanzen |
| DE3151017A1 (de) * | 1981-12-23 | 1983-06-30 | W. Antpöhler GmbH & Co KG, 4795 Delbrück | Maschine zum schneiden von teigstraengen in scheiben und verfahren zur gebaeckherstellung unter verwendung der maschine |
| DE19542721A1 (de) * | 1995-11-16 | 1997-05-22 | Sgl Technik Gmbh | Verfahren zur Herstellen von Formkörpern aus Kunststoff-Füllstoff-Mischungen mit einem hohen Gehalt an Füllstoffen |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1670925B2 (de) * | 1967-09-19 | 1977-03-10 | Bayer Ag, 5090 Leverkusen | 1,3,4-thiadiazolylharnstoffe |
| GB1195672A (en) * | 1968-02-01 | 1970-06-17 | Mobil Oil Corp | Novel Urea Derivatives and Herbicides containing the same |
| CH498859A (de) * | 1968-07-17 | 1970-11-15 | Agripat Sa | Verfahren zur Herstellung von Thiadiazolyl-harnstoffen |
| CH521711A (de) * | 1968-12-23 | 1972-04-30 | Bayer Ag | Herbizides Mittel |
| GB1290223A (instruction) * | 1969-04-21 | 1972-09-20 |
-
1968
- 1968-07-17 CH CH1069168A patent/CH498859A/de not_active IP Right Cessation
- 1968-07-17 CH CH1288770A patent/CH502762A/de not_active IP Right Cessation
-
1969
- 1969-07-14 DK DK380269AA patent/DK139357B/da unknown
- 1969-07-16 IL IL32632A patent/IL32632A/en unknown
- 1969-07-16 ES ES369572A patent/ES369572A1/es not_active Expired
- 1969-07-16 FR FR6924179A patent/FR2013116A1/fr not_active Withdrawn
- 1969-07-16 AT AT683269A patent/AT291668B/de not_active IP Right Cessation
- 1969-07-16 DE DE19691936241 patent/DE1936241A1/de active Pending
- 1969-07-16 ES ES369570A patent/ES369570A1/es not_active Expired
- 1969-07-16 BG BG012671A patent/BG16312A3/bg unknown
- 1969-07-16 GB GB35803/69A patent/GB1282308A/en not_active Expired
- 1969-07-16 ES ES369569A patent/ES369569A1/es not_active Expired
- 1969-07-16 NL NL6910940A patent/NL6910940A/xx not_active Application Discontinuation
- 1969-07-16 BE BE736171A patent/BE736171A/xx unknown
- 1969-07-16 JP JP5603969A patent/JPS5440610B1/ja active Pending
- 1969-07-16 PL PL1969134858A patent/PL80180B1/pl unknown
- 1969-07-16 RO RO60545A patent/RO61084A/ro unknown
- 1969-07-16 ES ES369571A patent/ES369571A1/es not_active Expired
- 1969-07-16 CS CS502869A patent/CS157651B2/cs unknown
Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8063081B2 (en) * | 2002-06-27 | 2011-11-22 | Novo Nordisk A/S | Aryl carbonyl derivatives as therapeutic agents |
| US7897628B2 (en) | 2002-06-27 | 2011-03-01 | Novo Nordisk A/S | Aryl carbonyl derivatives as therapeutic agents |
| US7598391B2 (en) | 2004-01-06 | 2009-10-06 | Novo Nordisk A/S | Heteroaryl-ureas and their use as glucokinase activators |
| US7851636B2 (en) | 2004-01-06 | 2010-12-14 | Novo Nordisk A/S | Heteroaryl-ureas and their use as glucokinase activators |
| US7872139B2 (en) | 2004-01-06 | 2011-01-18 | Novo Nordisk A/S | Heteroaryl-ureas and their use as glucokinase activators |
| USRE45183E1 (en) | 2004-01-06 | 2014-10-07 | Novo Nordisk A/S | Heteroaryl-ureas and their use as glucokinase activators |
| US8263634B2 (en) | 2004-01-06 | 2012-09-11 | Novo Nordisk A/S | Heteroaryl-ureas and their use as glucokinase activators |
| US7582769B2 (en) | 2005-07-08 | 2009-09-01 | Novo Nordisk A/S | Dicycloalkyl urea glucokinase activators |
| US7999114B2 (en) | 2005-07-08 | 2011-08-16 | Novo Nordisk A/S | Dicycloalkylcarbamoyl ureas as glucokinase activators |
| RU2443691C2 (ru) * | 2005-07-14 | 2012-02-27 | Транстех Фарма, Инк. | Мочевинные активаторы глюкокиназы |
| WO2007006814A1 (en) * | 2005-07-14 | 2007-01-18 | Novo Nordisk A/S | Urea glucokinase activators |
| AU2006268589B2 (en) * | 2005-07-14 | 2011-09-29 | Vtv Therapeutics Llc | Urea glucokinase activators |
| CN101263131B (zh) * | 2005-07-14 | 2013-04-24 | 特兰斯特克药品公司 | 脲葡糖激酶活化剂 |
| US8586614B2 (en) | 2005-07-14 | 2013-11-19 | Novo Nordisk A/S | Urea glucokinase activators |
| US7884210B2 (en) | 2005-07-14 | 2011-02-08 | Novo Nordisk A/S | Ureido-thiazole glucokinase activators |
| US8138185B2 (en) | 2007-01-09 | 2012-03-20 | Novo Nordisk A/S | Urea glucokinase activators |
| US8318778B2 (en) | 2007-01-11 | 2012-11-27 | Novo Nordisk A/S | Urea glucokinase activators |
| US8362049B2 (en) | 2007-01-11 | 2013-01-29 | Novo Nordisk A/S | Urea glucokinase activators |
| US11833136B2 (en) | 2018-06-12 | 2023-12-05 | Vtv Therapeutics Llc | Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs |
| US11974989B2 (en) | 2018-06-12 | 2024-05-07 | Vtv Therapeutics Llc | Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs |
| US12391658B2 (en) | 2020-02-18 | 2025-08-19 | Vtv Therapeutics Llc | Sulfoxide and sulfone glucokinase activators and methods of use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| BG16312A3 (bg) | 1972-08-20 |
| CH498859A (de) | 1970-11-15 |
| NL6910940A (instruction) | 1970-01-20 |
| DK139357B (da) | 1979-02-05 |
| ES369570A1 (es) | 1971-06-01 |
| ES369571A1 (es) | 1971-06-01 |
| DK139357C (instruction) | 1979-07-16 |
| JPS5440610B1 (instruction) | 1979-12-04 |
| BE736171A (instruction) | 1970-01-16 |
| FR2013116A1 (instruction) | 1970-03-27 |
| ES369569A1 (es) | 1971-06-01 |
| IL32632A (en) | 1973-03-30 |
| ES369572A1 (es) | 1971-06-01 |
| PL80180B1 (instruction) | 1975-08-30 |
| AT291668B (de) | 1971-07-26 |
| IL32632A0 (en) | 1969-09-25 |
| RO61084A (instruction) | 1976-10-15 |
| DE1936241A1 (de) | 1970-02-12 |
| CS157651B2 (instruction) | 1974-09-16 |
| CH502762A (de) | 1971-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 48S | Specification amended (sect. 8/1949) | ||
| SPA | Amended specification published | ||
| PCNP | Patent ceased through non-payment of renewal fee |