GB1269697A - Preparation of cephalosporin compounds - Google Patents
Preparation of cephalosporin compoundsInfo
- Publication number
- GB1269697A GB1269697A GB42066/69A GB4206669A GB1269697A GB 1269697 A GB1269697 A GB 1269697A GB 42066/69 A GB42066/69 A GB 42066/69A GB 4206669 A GB4206669 A GB 4206669A GB 1269697 A GB1269697 A GB 1269697A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydrogen
- nitrogen
- aliphatic unsaturation
- ring
- bonded
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 6
- 229940124587 cephalosporin Drugs 0.000 title abstract 6
- -1 cephalosporin compounds Chemical class 0.000 title abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 8
- 229910052739 hydrogen Inorganic materials 0.000 abstract 8
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 7
- 150000001780 cephalosporins Chemical class 0.000 abstract 5
- 239000004215 Carbon black (E152) Substances 0.000 abstract 4
- 125000001931 aliphatic group Chemical group 0.000 abstract 4
- 229930195733 hydrocarbon Natural products 0.000 abstract 4
- 229910052757 nitrogen Inorganic materials 0.000 abstract 4
- 150000002430 hydrocarbons Chemical class 0.000 abstract 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- 125000004429 atom Chemical group 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 1
- NVIAYEIXYQCDAN-CLZZGJSISA-N 7beta-aminodeacetoxycephalosporanic acid Chemical compound S1CC(C)=C(C(O)=O)N2C(=O)[C@@H](N)[C@@H]12 NVIAYEIXYQCDAN-CLZZGJSISA-N 0.000 abstract 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000000010 aprotic solvent Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- FUBBGQLTSCSAON-PBFPGSCMSA-N cefaloglycin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)COC(=O)C)C(O)=O)=CC=CC=C1 FUBBGQLTSCSAON-PBFPGSCMSA-N 0.000 abstract 1
- 229950004030 cefaloglycin Drugs 0.000 abstract 1
- 229960000603 cefalotin Drugs 0.000 abstract 1
- ZAIPMKNFIOOWCQ-UEKVPHQBSA-N cephalexin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C)C(O)=O)=CC=CC=C1 ZAIPMKNFIOOWCQ-UEKVPHQBSA-N 0.000 abstract 1
- 229940106164 cephalexin Drugs 0.000 abstract 1
- VUFGUVLLDPOSBC-XRZFDKQNSA-M cephalothin sodium Chemical compound [Na+].N([C@H]1[C@@H]2N(C1=O)C(=C(CS2)COC(=O)C)C([O-])=O)C(=O)CC1=CC=CS1 VUFGUVLLDPOSBC-XRZFDKQNSA-M 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- FZHAPNGMFPVSLP-UHFFFAOYSA-N silanamine Chemical compound [SiH3]N FZHAPNGMFPVSLP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052710 silicon Inorganic materials 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75499268A | 1968-08-23 | 1968-08-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1269697A true GB1269697A (en) | 1972-04-06 |
Family
ID=25037254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB42066/69A Expired GB1269697A (en) | 1968-08-23 | 1969-08-22 | Preparation of cephalosporin compounds |
Country Status (15)
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4181656A (en) | 1976-01-15 | 1980-01-01 | Glaxo Group Limited | Manufacture of semi-synthetic penicillin antibiotics |
| US4182709A (en) * | 1976-01-15 | 1980-01-08 | Glaxo Group Limited | Manufacture of semi-synthetic penicillin antibiotics |
| CN103193799A (zh) * | 2013-03-29 | 2013-07-10 | 武汉回盛生物科技有限公司 | 一种硫酸头孢喹肟的化学合成方法 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1053313B (it) * | 1976-01-15 | 1981-08-31 | Ankerfarm Spa | Procedimento per produrre antibiotici semisintetici |
| IT1063088B (it) * | 1976-06-01 | 1985-02-11 | Dobfar Spa | Derivati azetidinonici e procedimento per la preparazione di cefalosporine |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE311519B (enrdf_load_stackoverflow) * | 1962-12-14 | 1969-06-16 | Astra Ab |
-
1969
- 1969-08-05 ZA ZA695612A patent/ZA695612B/xx unknown
- 1969-08-12 IL IL32815A patent/IL32815A/xx unknown
- 1969-08-15 IE IE1159/69A patent/IE33571B1/xx unknown
- 1969-08-20 DE DE19691942454 patent/DE1942454A1/de not_active Ceased
- 1969-08-21 SE SE6911604A patent/SE385898B/xx unknown
- 1969-08-21 BE BE737761D patent/BE737761A/xx not_active IP Right Cessation
- 1969-08-22 JP JP44066045A patent/JPS5127676B1/ja active Pending
- 1969-08-22 NL NLAANVRAGE6912811,A patent/NL168840C/xx not_active IP Right Cessation
- 1969-08-22 FR FR6928829A patent/FR2016284B1/fr not_active Expired
- 1969-08-22 CY CY795A patent/CY795A/xx unknown
- 1969-08-22 CH CH1281569A patent/CH531005A/de not_active IP Right Cessation
- 1969-08-22 GB GB42066/69A patent/GB1269697A/en not_active Expired
- 1969-08-22 AT AT1070971A patent/AT313472B/de active
-
1974
- 1974-03-25 HK HK172/76*UA patent/HK17276A/xx unknown
-
1975
- 1975-12-30 MY MY103/75A patent/MY7500103A/xx unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4181656A (en) | 1976-01-15 | 1980-01-01 | Glaxo Group Limited | Manufacture of semi-synthetic penicillin antibiotics |
| US4182709A (en) * | 1976-01-15 | 1980-01-08 | Glaxo Group Limited | Manufacture of semi-synthetic penicillin antibiotics |
| CN103193799A (zh) * | 2013-03-29 | 2013-07-10 | 武汉回盛生物科技有限公司 | 一种硫酸头孢喹肟的化学合成方法 |
| CN103193799B (zh) * | 2013-03-29 | 2015-08-12 | 武汉回盛生物科技有限公司 | 一种硫酸头孢喹肟的化学合成方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| IL32815A0 (en) | 1969-11-12 |
| NL168840C (nl) | 1982-05-17 |
| DE1942454A1 (de) | 1970-08-27 |
| FR2016284A1 (enrdf_load_stackoverflow) | 1970-05-08 |
| NL168840B (nl) | 1981-12-16 |
| ZA695612B (en) | 1971-03-31 |
| IL32815A (en) | 1974-06-30 |
| BE737761A (enrdf_load_stackoverflow) | 1970-02-23 |
| SE385898B (sv) | 1976-07-26 |
| JPS5127676B1 (enrdf_load_stackoverflow) | 1976-08-13 |
| FR2016284B1 (enrdf_load_stackoverflow) | 1974-02-01 |
| IE33571B1 (en) | 1974-08-21 |
| AT313472B (de) | 1974-02-25 |
| NL6912811A (enrdf_load_stackoverflow) | 1970-02-25 |
| HK17276A (en) | 1976-04-02 |
| CH531005A (de) | 1972-11-30 |
| CY795A (en) | 1976-12-01 |
| MY7500103A (en) | 1975-12-31 |
| IE33571L (en) | 1970-02-23 |
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