GB1262971A - Stabilization of oestrogen-sulphate - Google Patents

Stabilization of oestrogen-sulphate

Info

Publication number
GB1262971A
GB1262971A GB1619069A GB1619069A GB1262971A GB 1262971 A GB1262971 A GB 1262971A GB 1619069 A GB1619069 A GB 1619069A GB 1619069 A GB1619069 A GB 1619069A GB 1262971 A GB1262971 A GB 1262971A
Authority
GB
United Kingdom
Prior art keywords
stabilization
oestrogen
sulphate
alkyl
zero
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1619069A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Laboratories Ltd
Original Assignee
Organon Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Laboratories Ltd filed Critical Organon Laboratories Ltd
Publication of GB1262971A publication Critical patent/GB1262971A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

Abstract

1,262,971. Stabilization of estrogen sulphates. ORGANON LABORATORIES Ltd. 27 March, 1969 [10 April, 1968], No. 16190/69. Heading C2U. Alkali metal sulphates of estrone, equilin and equilenin are stabilized by addition of amines of the formula wherein X is H, or C 1-6 alkyl or hydroxyalkyl, n is zero or 1, R 1 and R 2 are C 1-6 alkylene, and R 3 and R 4 are absent if n is zero or R 3 is H or C 1-6 alkyl and R 4 is H if n is 1. Stability may be further improved by addition of other substances such as calcium triphosphate and lactose.
GB1619069A 1968-04-10 1969-03-27 Stabilization of oestrogen-sulphate Expired GB1262971A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL6805153A NL6805153A (en) 1968-04-10 1968-04-10

Publications (1)

Publication Number Publication Date
GB1262971A true GB1262971A (en) 1972-02-09

Family

ID=19803313

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1619069A Expired GB1262971A (en) 1968-04-10 1969-03-27 Stabilization of oestrogen-sulphate

Country Status (6)

Country Link
BE (1) BE731328A (en)
DE (1) DE1918291A1 (en)
DK (1) DK122260B (en)
FR (1) FR2007431A1 (en)
GB (1) GB1262971A (en)
NL (1) NL6805153A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU621706B2 (en) * 1989-01-24 1992-03-19 Abbott Laboratories Stabilizing system for solid dosage forms
US5288717A (en) * 1992-02-26 1994-02-22 American Home Products Corporation Alkali metal 8,9-dehydroestrone sulfate esters
JP2005515222A (en) * 2002-01-08 2005-05-26 バー・ラボラトリーズ，インコーポレイテッド Synthesis of a mixture of sulfated estrogens using a sulfur trioxide complex

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3112577B1 (en) 2020-07-15 2022-07-15 Psa Automobiles Sa METHOD FOR DETERMINING THE IGNITION ADVANCE OF AN INTERNAL COMBUSTION ENGINE WITH CONTROL IGNITION

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU621706B2 (en) * 1989-01-24 1992-03-19 Abbott Laboratories Stabilizing system for solid dosage forms
US5288717A (en) * 1992-02-26 1994-02-22 American Home Products Corporation Alkali metal 8,9-dehydroestrone sulfate esters
JP2005515222A (en) * 2002-01-08 2005-05-26 バー・ラボラトリーズ，インコーポレイテッド Synthesis of a mixture of sulfated estrogens using a sulfur trioxide complex

Also Published As

Publication number Publication date
BE731328A (en) 1969-10-10
NL6805153A (en) 1969-10-14
FR2007431A1 (en) 1970-01-09
DE1918291A1 (en) 1969-10-23
DK122260B (en) 1972-02-14

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