GB1253831A - 9alpha,21-DIHALOPREGNANE COMPOUNDS - Google Patents

9alpha,21-DIHALOPREGNANE COMPOUNDS

Info

Publication number
GB1253831A
GB1253831A GB3100/68A GB310068A GB1253831A GB 1253831 A GB1253831 A GB 1253831A GB 3100/68 A GB3100/68 A GB 3100/68A GB 310068 A GB310068 A GB 310068A GB 1253831 A GB1253831 A GB 1253831A
Authority
GB
United Kingdom
Prior art keywords
dihalopregnane
9alpha
compounds
alkanoyl
jan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3100/68A
Other languages
English (en)
Inventor
Joseph Elks
Gordon Hanley Phillips
Peter John May
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Priority to GB3100/68A priority Critical patent/GB1253831A/en
Priority to CA040,409A priority patent/CA952900A/en
Priority to FR6900781A priority patent/FR2000443A1/fr
Priority to NL6900795A priority patent/NL6900795A/xx
Priority to IE70/69A priority patent/IE33204B1/xx
Priority to BR205681/69A priority patent/BR6905681D0/pt
Priority to DE19691902340 priority patent/DE1902340C3/de
Priority to DK26769AA priority patent/DK126500B/da
Priority to NO205/69A priority patent/NO132100C/no
Priority to ES362679A priority patent/ES362679A1/es
Priority to IL31447A priority patent/IL31447A/en
Priority to CH116472A priority patent/CH564563A5/xx
Priority to BE727109D priority patent/BE727109A/xx
Priority to CH77569A priority patent/CH564035A5/xx
Priority to SE00710/69A priority patent/SE350035B/xx
Priority to US00044565A priority patent/US3721687A/en
Publication of GB1253831A publication Critical patent/GB1253831A/en
Priority to NLAANVRAGE7811738,A priority patent/NL170421C/xx
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/20—Light-tight connections for movable optical elements
    • G02B7/22—Extensible connections, e.g. bellows

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Moulds For Moulding Plastics Or The Like (AREA)
GB3100/68A 1968-01-19 1968-01-19 9alpha,21-DIHALOPREGNANE COMPOUNDS Expired GB1253831A (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
GB3100/68A GB1253831A (en) 1968-01-19 1968-01-19 9alpha,21-DIHALOPREGNANE COMPOUNDS
CA040,409A CA952900A (en) 1968-01-19 1969-01-17 Anti-inflammatory steroids of the pregnane series and processes for their preparation
FR6900781A FR2000443A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1968-01-19 1969-01-17
NL6900795A NL6900795A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1968-01-19 1969-01-17
IE70/69A IE33204B1 (en) 1968-01-19 1969-01-17 "9alpha, 21-dihalopregnane compounds"
BR205681/69A BR6905681D0 (pt) 1968-01-19 1969-01-17 Processo de preparacao de compostos esteroides da serie do preguano
DE19691902340 DE1902340C3 (de) 1968-01-19 1969-01-17 21-Halogen-17alpha-monoester-pregnal,4-dien-3,20-dion-Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen
DK26769AA DK126500B (da) 1968-01-19 1969-01-17 Analogifremgangsmåde til fremstilling af 11-oxygenerede 9α,21-dihalogen-17α-alkanoyloxy-pregn-4-en-3,20-dioner.
ES362679A ES362679A1 (es) 1968-01-19 1969-01-18 Un procedimiento para la preparacion de nuevos esteroides anti-inflamatorios, de la serie del pregnano.
NO205/69A NO132100C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1968-01-19 1969-01-18
IL31447A IL31447A (en) 1968-01-19 1969-01-19 Anti-inflammatory 9,21 dihalo-17-alkanoyloxy-3,20-dioxo-delta4 and delta1,4 steroids of the pregnane series
CH116472A CH564563A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1968-01-19 1969-01-20
BE727109D BE727109A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1968-01-19 1969-01-20
CH77569A CH564035A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1968-01-19 1969-01-20
SE00710/69A SE350035B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1968-01-19 1969-01-20
US00044565A US3721687A (en) 1968-01-19 1970-06-08 3-keto-delta 4-9alpha-halo-11-oxygenated-16-methyl or methylene-17alpha-acyloxy-20-keto-21-halo pregnenes
NLAANVRAGE7811738,A NL170421C (nl) 1968-01-19 1978-11-30 Werkwijze voor het bereiden van een geneesmiddel tegen ontstekingen, alsmede het aldus verkregen gevormde geneesmiddel en een werkwijze voor het bereiden van verbindingen geschikt voor gebruik bij de bereiding van een zodanig geneesmiddel.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3100/68A GB1253831A (en) 1968-01-19 1968-01-19 9alpha,21-DIHALOPREGNANE COMPOUNDS

Publications (1)

Publication Number Publication Date
GB1253831A true GB1253831A (en) 1971-11-17

Family

ID=9751941

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3100/68A Expired GB1253831A (en) 1968-01-19 1968-01-19 9alpha,21-DIHALOPREGNANE COMPOUNDS

Country Status (14)

Country Link
US (1) US3721687A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE727109A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR6905681D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA952900A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (2) CH564035A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK126500B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES362679A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2000443A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1253831A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE33204B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL31447A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL6900795A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO132100C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE350035B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4377575A (en) * 1978-04-25 1983-03-22 Hoechst Aktiengesellschaft Corticoid-17-(alkyl carbonates) and process for their manufacture

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1429184A (en) * 1972-04-20 1976-03-24 Allen & Hanburys Ltd Physically anti-inflammatory steroids for use in aerosols
US4044126A (en) * 1972-04-20 1977-08-23 Allen & Hanburys Limited Steroidal aerosol compositions and process for the preparation thereof
US4154748A (en) * 1978-01-20 1979-05-15 The Upjohn Company Phosphate catalyzed acylation of steroidal tertiary alcohols
US4336200A (en) * 1980-01-31 1982-06-22 The Upjohn Company 17α-Acyloxy-5β-corticoids
DE3260474D1 (en) * 1981-02-02 1984-09-06 Schering Corp Aromatic heterocyclic esters of steroids, their preparation and pharmaceutical compositions containing them
IT1194178B (it) * 1983-03-29 1988-09-14 Ricerche Steroidi Sirs Spa Soc Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti
ES2078175B1 (es) * 1993-12-31 1996-10-16 Cusi Lab Formulacion farmaceutica conteniendo clobetasona y tobramicina y sus aplicaciones.
US20040022741A1 (en) * 2001-06-15 2004-02-05 Crutchfield Charles E. Topical steroid spray
US20090304603A1 (en) * 2001-06-15 2009-12-10 Cuticeuticals, Inc. Topical steroid spray with botanic seed oils
CA2537185A1 (en) * 2003-08-29 2005-03-10 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-iv
EP1694655A2 (en) * 2003-11-26 2006-08-30 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
WO2007031838A1 (en) 2005-09-16 2007-03-22 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
US20090054382A1 (en) * 2005-10-19 2009-02-26 Abhijit Ray Compositions of phosphodiesterase type iv inhibitors
JP2009512676A (ja) 2005-10-19 2009-03-26 ランバクシー ラボラトリーズ リミテッド ムスカリン性受容体アンタゴニストの医薬組成物
US20100029728A1 (en) * 2006-09-22 2010-02-04 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
AU2007298549A1 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-IV
EP1958947A1 (en) 2007-02-15 2008-08-20 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type 4
CN103497185A (zh) * 2007-03-14 2014-01-08 兰贝克赛实验室有限公司 用作磷酸二酯酶抑制剂的吡唑并(3,4-b)吡啶衍生物
EP2124943A1 (en) * 2007-03-14 2009-12-02 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b]pyridine derivatives as phosphodiesterase inhibitors
US8796248B2 (en) 2007-10-05 2014-08-05 Nektar Therapeutics Oligomer-corticosteroid conjugates
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
CN101812107B (zh) * 2010-04-20 2013-05-01 浙江仙居仙乐药业有限公司 一种合成丙酸氯倍他索的方法
US8900626B2 (en) 2011-06-20 2014-12-02 Senju Usa, Inc. Transdermal drug delivery system and method of using the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4377575A (en) * 1978-04-25 1983-03-22 Hoechst Aktiengesellschaft Corticoid-17-(alkyl carbonates) and process for their manufacture

Also Published As

Publication number Publication date
CA952900A (en) 1974-08-13
US3721687A (en) 1973-03-20
IL31447A (en) 1973-11-28
ES362679A1 (es) 1971-02-01
DE1902340B2 (de) 1977-06-08
IE33204B1 (en) 1974-04-17
NO132100C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-09-17
DK126500B (da) 1973-07-23
BR6905681D0 (pt) 1973-02-08
IE33204L (en) 1969-07-19
DE1902340A1 (de) 1969-09-11
IL31447A0 (en) 1969-03-27
BE727109A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-07-22
SE350035B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1972-10-16
FR2000443A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-09-05
NO132100B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-06-09
NL6900795A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-07-22
CH564563A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-07-31
CH564035A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-07-15

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